tannins drugs
TRANSCRIPT
CATECHU
Synonyms – Pale catechu, gambier,
kattha
Biological source – It consists of the dried
aqueous extract prepared from the
leaves of Uncaria gambier
Family - Rubiaceae
Chemical constituents –
It contains tannins like catechins and
catechu tannic acid
It contains flavonoids like quercetin and
fluorescent substances Gambier
fluorescein.
It also contains catechu- red, pyrogallol,
fixed oil and waxes
Uses –
Used as an astringent
Used in the treatment of diarrhoea
Used in the preparation of lozenges
BLACK CATECHU
Biological source –
It consists of the dried aqueous extract
prepared from heart wood of Acacia
catechu and Acacia chundra
Family - Leguminosae
Chemical constituents –
It contains tannins like catechins and
catechu tannic acid
It contains flavonoids like quercetin.
Others like Catechu- red and gum
Uses –
Used as an astringent, used in diarrhoea
Used as a cooling and digestive agent
CHEMICAL TESTS FOR CATECHU
1. Gambir Fluorescin test-
Alcoholic extract of drug, few drops of
sodium hydroxide mix and add
petroleum ether, shake and kept aside
for few minutes – petroleum ether layer
shows green fluorescence ( + ve for pale
catechu due Gambir Fluorescin )
2. Match stick test ( Catechins test) –
A match stick is dipped in aqueous plant
extract , dried near burner and
moistened with Hcl. On warming near
flame , the match stick wood turns pink
or red due to the formation of
phloroglucinol.
3. Vanillin – Hydrochloric acid test –
Test solution and few drops of Vanillin –
Hydrochloric acid reagent – A red or pink is
formed due the formation of phloroglucinol.
4. Chlorophyll test -
Powdered drug is heated with chloroform on
a water bath for 1-2 minutes .The organic
layer is filtered in a china dish and
evaporated on the water bath– green
residue
TANNIC ACID
Biological source –
It is obtained from the nutgalls. Galls are
vegetable outgrowths found on the young
twigs of Quercus infectoria
Family - Fagaceae
Tannic acid is a hydrolysable tannin and
yields Gallic acid and glucose on hydrolysis
Uses –
Used as an astringent
Used externally in the treatment of burns
Used as an antidote for alkaloid
poisoning
NUTGALL Synonym – Turkey galls
Biological source – Galls are the pathological
outgrowths formed on the twigs of the oak
tree Quercus infectoria
Family - Fagaceae
Chemical constituents – 40-60% of tannic
acid
Uses- Used as an astringent, used in the
manufacture of tannic acid
QUESTIONS –
Define tannins and explain various methods of estimation of
tannins.10 M
Write a note on general properties and method of isolation of
tannins. 10M
Write the source, active constituents and uses of Catechu and
Nutgall.5M
Explain the different types of tannins with examples.5M
Write a note on Goldbeaters’ test and its significances.5M
Write a note on estimation of Hydrolysable tannins.5M
Give the chemical tests for the identification of Catechu
and Tannic acid.5M
Give an account of Catechu.5M
What are tannins? Give general chemical tests to identify
them.5M
Define Tannins. How will you differentiate True tannins
from pseudo tannins ? 5M
Write in brief about Nut gall. 2M
Chemical tests for the identification of tannins.2M
What is tannic acid and give its uses.2M
Gambir- Flurorescin test and its significances.2M
Define Pseudo- tannins and give examples. 2M