Team IMACIntegrative Medicine and Cancer

Peter FrechetteStephanie GalanieKevin GuAnna HungSarah KimKelsey Merrick

Krupa Nataraj

Jessica Nooralian

Mihir PatelJessica StevensVivian WangAlbert Zhou

Mentor: Dr. Mark Kantor

Introduction

Cancer – a leading cause of death

Complementary and Alternative Medicine (CAM)

Many patients seek alternative treatments

CAM is still largely unexplored

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Literature Review

The use of CAM Ingestible herbal supplements Reasons for CAM use

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Objective

To investigate the use and perceptions of herbal dietary supplements among a group of female breast cancer survivors and test the effects and safety of the most commonly used herbal dietary supplements.

Methodology (Mixed-Method Design)

Questionnaire (descriptive, quantitative/qualitative)

Laboratory work (experimental, quantitative)

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Survey Purpose

To understand patients’ uses/perceptions of herbal dietary supplements Most commonly used Frequency Perceived efficacy/safety Reasons for use Sources of information

Questionnaire - Example

Sampling Frame Options

George Washington University Medical Center Paper survey

Georgetown University Paper survey

BreastCancer.Net News Online survey

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Survey Analysis

Frequency and statistical correlation Limitations

Sampling error Response error Non-response error

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Lab Work

Dr. Tom Wang Agricultural Research Service; Diet, Genetics,

and Immunology (USDA) Effects – Proliferation and Cell Cycle

Dr. Tom Flynn Center for Food Safety and Applied Nutrition;

Department of Toxicology (FDA) Safety – Liver Toxicity

Conclusion

Objective Investigate the use and perceptions of

herbal dietary supplements of female breast cancer survivors and test the effects and safety of the most commonly used herbal dietary supplements

Publication in scholarly journal

Contribution to literature

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Timeline (I)

Spring 2008

• Thesis proposal

• Obtain IRB approval

• Develop and pilot survey

• Design laboratory experiments

• Create team website

Fall 2008

• Administer surveys

• Outline thesis

• Draft literature review for thesis

• Fall colloquia

• Begin lab research

Spring 2009

• Finish survey data collection

•Organize survey data

• Draft chapters 1, 2, and 3 of thesis

• Undergraduate Research Day

• Continue lab research

Timeline (II)

Fall 2009

• Complete survey data analysis

• Draft chapters 4 and 5

• Draft presentation for thesis conference

• Five experts for conference panel

• Finish lab data collection and analysis

Spring 2010

•Submit final team information

•Finish thesis

•Thesis conference

•Submit final thesis for publication

Budget

Surveying costs Online advertisement or

printing Statistician consultation fees

Laboratory costs Supplements Cell line media

Future conferences

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Acknowledgements

Dr. Kantor, Team Mentor

Dr. Tom Wang

Dr. Tom Flynn

Dr. Gordon Willis

Dr. James Wallace

Dr. Rebecca Thomas

Courtenay Barrett

Thank You.

Questions?