CORRECTION Temporal patterns of cytokine and apoptosis-related

gene expression in spinal cords of the G93A-SOD1

mouse model of amyotrophic lateral sclerosis

Kenneth Hensley,*,� Robert A. Floyd,*,� Brian Gordon,� Shenyun Mou,*Quentin N. Pye,* Charles Stewart,* Melinda West* and Kelly Williamson*

*Free Radical Biology and Aging Research Program, and �Laboratory Animal Resource Center,

Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA

�Oklahoma Center for Neuroscience, University of Oklahoma Health Science Center, Oklahoma City,

Oklahoma, USA

Several asterisks indicating statistical significance were omitted from Table 2 of the above article (J. Neurochem. 80,

pp. 365–374). The amended Table 2 is reproduced below. Please also note the value for IFNc(M) in column 2 is 122 ± 4*.

Table 2 Summary of quantitative RPA data

80 days

% change

relative to

non-Tg mice

120 days

% change

relative to

wt-hSOD mice

non-Tg

mice

Cytokines

IL1a 217 ± 22* 397 ± 10* 294 ± 17*

IL1b 178 ± 18* 760 ± 27* 183 ± 18*

IL1RA 355 ± 20* 2085 ± 13* 415 ± 14*

IL6 ND 155 ± 5* ND

IL10(M) 133 ± 21 117 ± 6 127 ± 18

IL10(L) 115 ± 6 – 93 ± 7

IL12-p35 235 ± 15* 135 ± 8* 131 ± 19

IL18 158 ± 20* 99 ± 3 107 ± 7

MIF 116 ± 3* 73 ± 3* 89 ± 7

IFNc(M) 112 ± 5 122 ± 4* 119 ± 8

IFNc(L) 118 ± 12 – ND

IL2 ND – 90 ± 7

IL3 ND – 99 ± 9

IL4 ND – 123 ± 9

IL5 118 ± 22 – 95 ± 7

IL15 118 ± 6 – 80 ± 6

Caspases

caspase 1 91 ± 13 290 ± 6* 275 ± 14*

caspase 2 104 ± 5 136 ± 3* 106 ± 12

caspase 3 104 ± 5 207 ± 2* 120 ± 20

caspase 6 101 ± 8 228 ± 3* 145 ± 18*

Table 2 (Continued)

80 days

% change

relative to

non-Tg mice

120 days

% change

relative to

wt-hSOD mice

non-Tg

mice

caspase 7 112 ± 18 241 ± 5* 147 ± 9*

caspase 8 101 ± 12 420 ± 4* 204 ± 21*

caspase 11 88 ± 25 461 ± 6* 228 ± 7*

caspase 12 99 ± 16 668 ± 6* 286 ± 8*

Death receptors

caspase 8 159 ± 17* 364 ± 12* 280 ± 7*

Fas 66 ± 16 269 ± 6* 420 ± 4*

FasL 90 ± 10 95 ± 11 147 ± 6*

FADD 150 ± 8* 145 ± 5* 119 ± 3*

FAF 118 ± 7 109 ± 9 82 ± 2*

FAP 136 ± 13 92 ± 7 90 ± 2

TNFR-p55 164 ± 6* 357 ± 5* 333 ± 5*

TRAIL 51 ± 17* 100 ± 7 92 ± 4

TRADD 107 ± 4 100 ± 3 ND

RIP 115 ± 6 173 ± 7* 174 ± 6*

Values obtained from G93A-SOD1 mice are expressed as a relative

percentage to the mean value obtained from non-Tg or wt-SOD1 mice

at each age. Error estimates refer to the SEM; n ¼ 5–7 per group;

*p < 0.05 by individual t-tests. ND, below detection limits; (M), denotes

value obtained from monokine probe set; (L) denotes value from lym-

phokine probe set. Omissions indicate no data collected.

Journal of Neurochemistry, 2002, 82, 1570

1570 � 2002 International Society for Neurochemistry, Journal of Neurochemistry, 82, 1570