Surpporting information

Selective cytotoxic eremophilane-type sesquiterpenes from Penicillium

citreonigrum

Wei-Hua Yuana,b*, Masuo Gotob, Kan-Yen Hsiehb,c, Bo Yuana, Yu Zhaob,

Susan L Morris-Natschkeb, Kuo-Hsiung Leeb,d*

a) Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province,

Jiangsu Normal University, Xuzhou 221116, China.

b) Natural Product Research Laboratories, UNC Eshelman School of Pharmacy,

University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7568, USA.

c) Natural Products Research Institute, Kaohsiung Medical University, Kaohsiung,

Taiwan.

d) Chinese Medicine Research and Development Center, China Medical University

and Hospital, Taichung, Taiwan.

*Corresponding authors. Email: khlee@unc.edu (KHL), whyuan@jsnu.edu.cn (WHY).

Figure S1. 1H NMR spectra of 1 (in CDCl3, 400MHz).

Figure S2. 13C NMR spectra of 1 (in CDCl3, 100MHz).

Figure S3. COSY spectra of 1 (in CDCl3).

Figure S4. HMQC spectra of 1 (in CDCl3).

Figure S5. HMBC spectra of 1 (in CDCl3).

Figure S6. IR (KBr) spectra of 1.

Figure S7. UV (MeOH) spectra of 1.

Figure S8. 1H NMR spectra of 2 (in CDCl3, 400MHz).

Figure S9. 13C NMR spectra of 2 (in CDCl3, 100MHz).

Figure S10. HMQC spectra of 2 (in CDCl3).

Figure S11. COSY spectra of 2 (in CDCl3).

Figure S12. HMBC spectra of 2 (in CDCl3).