the 17th international conference on biomedical ... 2019_scientific programme.pdf · organisations...

PROGRAMME

The 17th International Conference on Biomedical Engineering

ICBME 2019The 17th International Conference on Biomedical Engineering9 – 12 December 2019, NUS Engineering, Singapore

www.icbme.org

Jointly organised by: Endorsed by:

2 | The 17th International Conference on Biomedical Engineering The 17th International Conference on Biomedical Engineering | 3

FOREWORD Dear colleagues and friends,

It is with great pride that we welcome you to the 17th International Conference on Biomedical Engineering (ICBME) 2019. Organised jointly by the Department of Biomedical Engineering of the National University of Singapore (NUS) and the Biomedical Engineering Society of Singapore (BES), ICBME 2019 aims to foster greater collaborations amongst experts, researchers, practitioners and students to further strengthen interactions and exchanges of information and knowledge in the field of biomedical engineering.

The ICBME series has attracted a greater number of participants at every meeting organised since its inaugural conference in 1983. This year, we are heartened to have received close to 400 papers from 26 countries and expect some 400 participants to discuss important trends and opportunities in the biomedical engineering sector over the next four days whilst enjoying your stay in this cosmopolitan city.

The Scientific Committee is immensely grateful to have the participation from an impressive roster of highly respected and esteemed speakers to lead the scientific programme. With more than 60 lectures, special symposia and thematic sessions combined, the scientific programme is testimony to the interdisciplinary nature of this field and we hope this platform continues to allow our fellow colleagues to showcase as well as keep abreast of the exciting developments in this meeting.

In addition to the exciting programme line up, ICBME 2019 also features the NUS Engineering Industry Day as part of the programme. Themed “Future Health Technology”, this unique half-day programme gathers industry partners, government agencies and academia to discuss and develop a strategic plan to drive healthtech innovation and enterprise in Singapore and beyond. We warmly welcome all delegates and faculty to visit our showcase of exciting technologies in Biofabrication, Bioimaging, Biosensors and Medical Robotics and explore potential collaborations.

On behalf of the Organising and Scientific Committees, we thank our delegates, speakers, exhibitors, sponsors and supporting organisations for making ICBME 2019 another successful meeting. Our continued partnership is what keeps the science of our field moving.

We wish you a fruitful meeting and memorable time here in Singapore.

Yours sincerely,

Prof. Chwee Teck LimChair17th ICBME Organising Committee

Prof. Hwa Liang LeoScientific Committee Chair17th ICBME Scientific Committee

ACKNOWLEDGMENTS We wish to thank the following supporting organisations and societies who, through their support, have helped make this Conference possible:

Organised by Endorsed by

Supported by

Held in Supported by

4 | The 17th International Conference on Biomedical Engineering

Table of Contents

FOREWORD ........................................................................................................................................................................ 2

ACKNOWLEDGMENTS ................................................................................................................................................... 3

TABLE OF CONTENTS .................................................................................................................................................... 4

ABOUT ICBME CONFERENCE SERIES .................................................................................................................... 6

ORGANISERS ....................................................................................................................................................................... 7

LOCAL ORGANISING COMMITTEE ............................................................................................................................ 8

INTERNATIONAL ADVISORY PANEL ........................................................................................................................ 9

INTERNATIONAL SCIENTIFIC COMMITTEE ........................................................................................................... 9

LOCAL SCIENTIFIC COMMITTEE ................................................................................................................................ 11

THEMES AND TOPICS ...................................................................................................................................................... 12

CONFERENCE LECTURE SPEAKERS ........................................................................................................................ 13

PLENARY SPEAKERS ....................................................................................................................................................... 13

KEYNOTE SPEAKERS ....................................................................................................................................................... 14

SPECIAL SYMPOSIA .......................................................................................................................................................... 17

GENERAL INFORMATION .............................................................................................................................................. 20

VENUE FLOOR PLAN ....................................................................................................................................................... 22

PROGRAMME-AT-A-GLANCE ....................................................................................................................................... 24

SCIENTIFIC PROGRAMME .............................................................................................................................................. 28

THE ICBME 2019ABSTRACT BOOK

IS ONLINE!Scan the QR code to download!

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ABOUT ICBME CONFERENCE SERIESThe ICBME is a series of international conference in biomedical engineering held in Singapore. Our past conferences have been successful in attracting over 600 participants from more than 30 countries.

Biomedical engineering is applied in most aspects of our healthcare ecosystem. From electronic health records to artificial intelligence, diagnostic tools to therapeutics, rehabilitative to regenerative treatments, the work of biomedical engineers is evident. Biomedical engineers work at the intersection of engineering, life sciences and healthcare. The engineers use principles from applied science including mechanical, electrical, chemical and computer engineering together with physical sciences including physics, chemistry and mathematics to apply them to biology and medicine. Applying such concepts to the human body is very much the same concepts that go into building and programming a machine. The goal is to better understand, replace or fix a target system to ultimately improve the quality of healthcare.

With this understanding, we have created this conference to o£er a single platform for individuals and organisations working in the biomedical engineering related fields to gather and network with each other in so doing create the catalyst for future development of biomedical engineering in Asia.

The 17th International Conference on Biomedical Engineering is endorsed by the International Federation for Medical and Biological Engineering (IFMBE).

ORGANISERS

Biomedical Engineering Society (Singapore)The Biomedical Engineering Society (Singapore) had its humble beginning in 1991, when a group of doctors and engineers who had been working together on biomedical engineering research projects decided to form a society to promote the field of Biomedical Engineering in Singapore.

The Founding President was Prof Kamal Bose an Orthopaedic Surgeon with a passion for interdisciplinary collaboration. He steered the Society during its early years and set the sight for academic excellence in biomedical engineering. He left a lasting legacy of successful conferences on biomedical engineering organised by the Society. Prof Chew Yong Tian succeeded Prof Bose as the second President of BES. Prof Chew, a Mechanical Engineer led the Society to greater heights. The conferences organised by the Society achieved international status.

In view of BES’ academic strength and its association to the various tertiary institutions, BES set up a Student Chapter in 2009. The Student Chapter organises the BES’ Scientific Meetings with participation of students from Junior Colleges, Polytechnics and Universities. BES launched the Industry Chapter on the 12th November 2011 as part of its 20th Anniversary Celebration.

Apart from creating these two synergistic platforms to address human capital development for the biomedical industry locally and regionally, BES is also well connected around the world. BES is a¦liated to the International Federation of Medical and Biological Engineering (IFMBE) since 1994. It allows the Society to plug into 65 sister societies around the world, boasting a total membership of 120,000 biomedical engineers.

For more information on the Society, please visit http://www.bes.org.sg/.

National University of Singapore, Faculty of Engineering, Department of Biomedical EngineeringThe NUS’ Department of Biomedical Engineering is a University Department which was established in 2002. Our talented academic sta£ has varied background in engineering, life sciences and medicine. Many of whom has joint appointments with either the YLL School of Medicine, Faculty of Science, Faculty of Engineering, Mechanobiology Institute or A*STAR Research Institutes. This is a reflection of the multidisciplinary and integrative approach taken in bioengineering research and education.

Broadly speaking, the core research expertise available in the department include Biomaterials, Biomechanics, Bionanotechnology, Biosignal Processing, Biosensors, Biomicrofluidics, Computational Methods with application in areas of Tissue Engineering, Therapeutic Delivery Systems, Biomedical Imaging and Instrumentation, and Medical Devices, to name a few.

The undergraduate programme, while designed to provide students with strong fundamental and broad based learning in engineering and life sciences, its approach is integrative and students are exposed to clinical applications as well. There is strong emphasis in engineering design in the curriculum. In fact, students have a choice to enroll in the Design-Centric Curriculum (DCC) under the theme “Engineering in Medicine”. In the final year, students are required to take on individual research projects.

Outstanding undergraduate students can enrol in the accelerated programme, the Global Engineering Programme (GEP) leading to the award of two degrees in 4 years, i.e. a Bachelor of Engineering (B.Eng.) at NUS and for those who qualify for admission to a top partner university, a Master degree in Engineering. An excellent PhD graduate programme is also available to train graduate students in multidisciplinary bioengineering research. Highly competitive research scholarships are o£ered to students that demonstrate potential in research.

For more information on the institution, please visit http://www.bioeng.nus.edu.sg/.


LOCAL ORGANISING COMMITTEEChair Chwee Teck Lim National University of Singapore

Co-Chair Dean Ho National University of Singapore

Secretary Alberto Corrias National University of Singapore

Treasurer Martin Buist National University of Singapore

Past Chair James Goh National University of Singapore

Scientific Chair Hwa Liang Leo National University of Singapore

Scientific Co-Chair Raye Yeow National University of Singapore

Technical & Social Visits Peck Ha Tan Ngee Ann Polytechnic

Anle Lin Biomedical Engineering Society (Singapore)

Sponsorship Sierin Lim Nanyang Technological University of Singapore

Publicity Siew Lok Toh National University of Singapore

Early Career Programme Han Wei Hou Nanyang Technological University of Singapore

Javier Gomez Fernandez Singapore University of Technology and Design

Venue & Logistics Chueh Loo Poh National University of Singapore Tony Kanchanawong National University of Singapore

INTERNATIONAL ADVISORY PANEL

INTERNATIONAL SCIENTIFIC COMMITTEE

Yoshinobu Baba Nagoya University

Zhenan Bao Stanford University

Dominique Barthes-Biesel University of Compiegne

Shu Chien University of California, San Diego

David Elad Tel Aviv University

Yubo Fan Beihang University

Gerhard Holzapfel Graz University of Technology

Peter Hunter University of Auckland

Roger Kamm Massachusetts Institute of Technology

Takehiko Kitamori University of Tokyo

Geert Schmid-Schobein University of California, San Diego

Michael Shuler Cornell University

Fong-Chin Su National Cheng Kung University

Mitsuo Umezu Waseda University

David Weitz Harvard University

Taiji Adachi Kyoto University Kang-Ping Lin Chung Yuan Christian University

Rashid Bashir University of Illinois Urbana-Champaign Mian Long Institute of Mechanics, Chinese Academy of Sciences

Anthony Bull Imperial College London Nigel Lovell University of New South Wales

Dennis Discher University of Pennsylvania Ratko Magjarevic University of Zagreb

Cheng Dong Penn State University

Josep Samitier Marti Institute for Bioengineering of Catalonia

Ross Ethier Georgia Institute of Technology Takeo Matsumoto Nagoya University

Amit Gefen Tel Aviv University Leandro Pecchia University of Warwick

Guy Genin Washington University at St Louis Beth Pruitt University of California, Santa Barbara

Justin Gooding University of New South Wales Heinz Redl Ludwig Boltzmann Institute


Farshid Guilak Washington University at St Louis John A. Rogers Northwestern University

X. Edward Guo Columbia University Ichiro Sakuma University of Tokyo

Amy Herr University of California, Berkeley Vivek Shenoy University of Pennsylvania

Walter Herzog University of Calgary Masahiro Sokabe Nagoya University

Marie-Christine Ho Ba Tho University of Technology of Compiegne Yu Sun University of Toronto

I-Ming Hsing Hong Kong University of Science and Technology Shoji Takeuchi University of Tokyo

Dietmar Hutmacher Queensland University of Technology Swee Hin Teoh Nanyang Technological University of Singapore

Taeghwan Hyeon Seoul National University Raymond Tong Chinese University of Hong Kong

Fatimah Ibrahim University of Malaya Nitish Thakor National University of Singapore

Takuji Ishikawa Tohoku University Jaw-Lin Wang National Taiwan University

Timo Jämsä University of Oulu Justin Cooper-White University of Queensland

Shankar Krishnan Wenworth University Ed X. Wu University of Hong Kong

Ernesto Iadanza University of Florence Younan Xia Georgia Institute of Technology

Piotr Ladyzynski Nalecz Institute of Biocybernetics and Biomedical Engineering Guang-Zhong Yang Imperial College London

Abraham Lee University of California, Irvine Leslie Yeo RMIT University

Peter Lee University of Melbourne Yong Ping Zheng Hong Kong Polytechnic University

Song Li University of California, Los Angeles Polona Žnidaršic Plazl University of Ljubljana

Feng-Huei Lin National Taiwan University

LOCAL SCIENTIFIC COMMITTEE

Hwa Liang Leo National University of Singapore

Kanyi Pu Nanyang Technological University of Singapore

Raye Yeow National University of Singapore

Anqi Qiu National University of Singapore

Ali Asgar Bhagat National University of Singapore

Hongliang Ren National University of Singapore

Chia-Hung Chen National University of Singapore

Vinicius Rosa National University of Singapore

Nanguang Chen National University of Singapore

Huilin Shao National University of Singapore

Peng Chen Nanyang Technological University of Singapore

Nguyen Vinh Tan Institute of High Performance Computing, A*STAR

Xiaodong Chen Nanyang Technological University of Singapore

Lay Poh Tan Nanyang Technological University of Singapore

Lih Feng Cheow National University of Singapore

Dalton Chor Yong Tay Nanyang Technological University of Singapore

Sing Yian Chew Nanyang Technological University of Singapore

Benjamin Tee National University of Singapore

Keng Hwee Chiam Institute of High Performance Computing, A*STAR

Yi-Chin Toh National University of Singapore

Desmond Chong Singapore Institute of Technology

Dieter Trau National University of Singapore

Mark Chong Nanyang Technological University of Singapore

Zhiping Wang Singapore Institute of Manufacturing Technology, A*STAR

Chee Kong Chui National University of Singapore

Yoke Rung Wong National Heart Centre

Fangsen Cui Institute of High Performance Computing, A*STAR

Chen Jie Xu Nanyang Technological University of Singapore

Eliza Fong National University of Singapore

Choon Hwai Yap National University of Singapore

John Ho National University of Singapore

Ai Ye Singapore University of Technology and Design

Zhiwei Huang National University of Singapore

Joo Chuan Yeo National University of Singapore

James Chen Yong Kah National University of Singapore

Haoyong Yu National University of Singapore

Sangho Kim National University of Singapore

Toyama Yusuke National University of Singapore

Vincent Lee National University of Singapore

Yong Zhang National University of Singapore

Jun Li National University of Singapore

Wenting Zhao National University of Singapore

Yansong Miao Nanyang Technological University of Singapore

Liang Zhong National Heart Centre

Kee Woei Ng Nanyang Technological University of Singapore


THEMES AND TOPICS

A: BioImaging & BioSignals1. Biomedical imaging2. Medical physics3. Biomedical instrumentation4. Biosignal processing

B: Bio-Micro/Nanotechnologies1. Biosensors2. BioMEMs3. Microfluidics & Lab-on-Chip 4. Multi-scale devices & systems5. Nanobiotechnology

C: BioRobotics & Medical Devices1. Computer-assisted surgery 2. Medical robotics 3. Rehabilitation engineering & assistive

technology 4. Exoskeletal & wearable devices5. Smart sensors6. Soft robotics

D: Biomaterials & Regenerative Medicine1. Artificial organs2. Biomaterials 3. Controlled drug delivery 4. Pharmaceutics 5. Tissue engineering 6. Bioprinting

E: BioMechanics & Mechanobiology1. Cardiovascular mechanics2. Cell and molecular mechanics3. Organ and tissue mechanics4. Orthopaedic biomechanics 5. Mechanobiology6. Sports biomechanics & human performance

F: Engineering/Synthetic Biology1. Cell-free synthetic biology2. Engineering synthetic ecosystems3. Microbial production of drugs4. Artificial cells5. Synthetic viruses6. Genetic engineering7. Artificial photosynthesis8. Computational designs9. Tools and techniques

G: Neuroengineering & Neurotechnology1. Neuroimaging2. Brain-machine interfaces3. Advanced brain monitoring4. Innovations in neurotechnology

H: Big Data, Healthcare Analytics & AI1. Telemedicine and healthcare2. Data mining and machine learning3. Cybersecurity4. Bioinformatics & digital medicine5. Clinical decision support systems6. AI in healthcare7. Personalised medicine

I: Bioelectronics & Electroceuticals1. Bioelectronic devices and applications2. Emerging characterization techniques, Devices

and materials3. Cell-material interface in natural systems

J: Computational Modeling1. Musculoskeletal2. Soft tissue3. Electro-physiology4. Biofluids

K: Clinical Engineering1. Health technology assessment2. Health technology management3. Clinical engineering4. Human factors

L: Biomedical Engineering Education1. Disruptive technology for education2. Innovations in biomedical engineering

education3. BioDesign in the BME curriculum

M: Human Disease Diagnosis & Therapy1. Diagnostics2. Therapeutics3. Immunotherapy4. Immuno-engineering5. Liquid biopsy6. Precision medicine

CONFERENCE LECTURE SPEAKERS

PLENARY SPEAKERS

Monday, 9 December

Time and Venue Session and Speaker

0930 - 1015Lecture Theatre 7A

Nanogenerators for Powering Implantable Medical Devices and Self-powered Sensors

Zhong Lin WangGeorgia Institute of Technology; Beijing Institute of Nanoenergy and NanosystemsChinese Academy of Sciences

Wednesday, 11 December


Materials in the Flatland

Sir Konstantin NovoselovNobel Prize in Physics, 2010National University of Singapore

Monday, 9 December



Plenary Lecture 1Nanobiodevices, Quantum Technology, and AI for Precision Medicine and Future Healthcare

Yoshinobu BabaNagoya University

Tuesday, 10 December


Plenary Lecture 2Microfluidic Precision Medicine – Processing the Minimal Representative Unit for Top-down Diagnostics and Bottom-up Treatment

Abraham LeeUniversity of California, Irvine


Plenary Lecture 3Frontiers of Biorobotics and Bionics Science and Engineering

Paolo DarioThe BioRobotics Institute, Scuola Superiore Sant’Anna



Plenary Lecture 4Reflections on Muscle Contraction

Walter HerzogUniversity of Calgary


PLENARY SPEAKERS

KEYNOTE SPEAKERS

Thursday, 12 December



Plenary Lecture 5AI and Data-Driven Support for Prevention, Intervention, and Cure in Healthcare

Beng Chin OoiNational University of Singapore

Monday, 9 December



Session 1.1: Cell Mechanics 1Mechanosensitive Ion Channels Play a Crucial Role in Substrate Rigidity Sensing in Mesenchymal Stem Cells

Masahiro SokabeNagoya University Graduate School of Medicine

1045 - 1115Engineering Auditorium

Session 1.2: 3D Bioprinting and Regenerative Medicine3D Bioprinting for Tissue and Tissue Model Fabrication

Y. Shrike ZhangHarvard Medical School

1045 - 1115Rm EA-02-11

Session 1.3: Smart DevicesWearable Sweat Sensors for Personalized Health Monitoring

Wei GaoCalifornia Institute of Technology

1045 - 1115Rm EA-06-03

Session 1.4: Human Disease Diagnosis & Therapy 1Nucleic Acid Based Bioengineering and Organic Electrochemical Transistor Based Flexible Bioelectronics

I-Ming HsingHong Kong University of Science and Technology

1045 - 1115Rm EA-06-05

Special Symposium 2: BioelectronicsWearable Sensors and Nanogenerators for Healthcare Applications

Chengkuo Vincent LeeNational University of Singapore


Session 1.5: Cell Mechanics 2Single Cell Biosensors for Dynamic Multigene Analysis in Complex Tissue Environments

Pak Kin WongPenn State University

1400 - 1430Rm EA-02-11

Session 1.7: Soft Robotics 1Soft Robotics in Biomedical Applications

Cecilia LaschiThe BioRobotics Institute, Scuola Superiore Sant’Anna

KEYNOTE SPEAKERS

Monday, 9 December


1400 - 1430Rm EA-06-05

Special Symposium 4: MechanobiologyCryoprotectant Enables Structural Control of Porous Sca©olds for Exploration of Cellular Mechano-Responsiveness in 3D

Yanan DuTsinghua University


Session 1.9: Cell Mechanics 3Electrostatic Switching of Nuclear Basket Conformations Provides a Potential Mechanism for Nuclear Mechanotransduction

Guy GeninWashington University in St Louis


Session 1.9: Cell Mechanics 3 Engineering of Cell Mechanical Microenvironment

Feng XuXi’An Jiaotong University

1600 - 1630Rm EA-06-03

Session 1.12: BME EducationDesigning a Medical Imaging and Optics Track in an Undergraduate Biomedical Engineering Program

Shankar KrishnanWentworth Institute of Technology

1630 - 1700Rm EA-06-03

Session 1.12: BME EducationBiomedical Engineering Education Program for Graduate Students at TWins, Waseda University

Mitsuo UmezuWaseda University

1600 - 1630Rm EA-06-04

Special Symposium 5: Wearable Sensing TechnologyStretchable Gold Nanowire Electrode – A New Wearable Electrochemical Biosensing Platform

Wenlong ChengMonash University

1630 - 1700Rm EA-06-04

Special Symposium 5: Wearable Sensing TechnologySkin – The Ultimate Window to Your Health

Zee UptonInstitute of Medical Biology

1600 - 1630Rm EA-06-05

Special Symposium 6: ExosomesExosomes and Mimetic Technologies for Therapeutics

Yong Song GhoPohang University of Science and Technology




0830 - 0900Rm EA-06-03

Session 2.4: Bio-Micro / Nanotechnologies 2Design and Fabrication Methods of Micro/Nanofluidics for Biomedical Applications: Example for Cytokine Analysis from Single Living B Cell

Takehiko KitamoriThe University of Tokyo

0830 - 0900Rm EA-06-04

Special Symposium 7: Cardiac Mechanics 1Patient Specific Factors Governing the Success of Trans-Catheter Aortic Valves

Lakshmi DasiThe Ohio State University



Session 3.1: Cardiovascular Biomechanics 1Multi-Level Modelling of Thrombolysis in Ischemic Stroke

Xiao Yun XuImperial College London

1045 - 1115Rm EA-06-03

Session 3.4: Bio-Micro / Nanotechnologies 3Gas-Phase Biosensors (Bio-Sni©er & Sni©-Cam) for Human Volatile Chemicals

Kohji MitsubayashiTokyo Medical and Dental University

1045 - 1115Rm EA-06-05

Special Symposium 9: Cardiac Mechanics 2Applicability of an Embryonic Vascular Growth Model in Pediatric Cardiovascular Surgeries

Kerem PekkanKoc University

1400 - 1430Engineering Auditorium

Session 3.7: Clinical Engineering 1CE-IT Alarm Management Technology to Improve Alarm Fatigue and Precision Nursing Based on Physiological Monitor Signals

Kang-Ping LinChung-Yuan Christian University

1400 - 1430Rm EA-06-03

Session 3.9: Bio-Micro / Nanotechnologies 4Go with the Flow

Oliver HaydenTechnical University of Munich

1600 - 1630Rm EA-06-03

Session 3.14Bio-Micro/ Nanotechnologies 5Microfluidics for Synthesis and Screening of Nanoscale Drug Carriers

Xingyu JiangSouthern University of Science and Technology

KEYNOTE SPEAKERS KEYNOTE SPEAKERS

SPECIAL SYMPOSIA



1045 - 1100Rm EA-02-11

Session 4.3: Neuroengineering / NeurotechnologyClimbing-Inspired Twining Electrodes and Buckled-Based3D Bioelectrodes for Peripheral Neuromodulation

Xue FengTsinghua University

Monday, 9 December

Time and Venue Symposium Chairperson(s)

1045 - 1215Rm EA-06-04

Symposium 1Rehabilitation Robotics

Raye YeowNational University of Singapore

Haoyong YuNational University of Singapore

1045 - 1215Rm EA-06-05

Symposium 2Bioelectronics

John HoNational University of Singapore

1400 - 1530Rm EA-06-04

Symposium 3Biomedical Nanotechnology

James KahNational University of Singapore

1400 - 1530Rm EA-06-05

Symposium 4Mechanobiology

Guy GeninWashington University in St Louis

1600 - 1730Rm EA-06-04

Symposium 5Wearable Sensing Technology

Benjamin TeeNational University of SingaporeJoo Chuan YeoNational University of Singapore

1600 - 1730Rm EA-06-05

Symposium 6Exosomes

Huilin ShaoNational University of Singapore

Wojtek ChrzanowskiThe University of Sydney Nano Institute


0830 - 1000Rm EA-06-04

Symposium 7Cardiac Mechanics 1

Choon Hwai YapNational University of Singapore

0830 - 1000Rm EA-06-05

Symposium 8Reproductive Bioengineering 1


David EladTel Aviv University


SPECIAL SYMPOSIA


Time and Venue Symposium Chairperson(s)

1045 - 1215Rm EA-06-05

Symposium 9Cardiac Mechanics 2


1400 - 1530Rm EA-06-05

Symposium 10Reproductive Bioengineering 2


David EladTel Aviv University

1600 - 1730 Rm EA-06-04

Symposium 11Surgical Robotics

Hongliang Ren National University of Singapore

1600 - 1730Rm EA-06-05

Symposium 12Organ-on-Chip

Ben MaozTel Aviv University

Danny Ben-ZviInstitute of Medical Research Israel-Canada The Hebrew University-Hadassah Medical School, Jerusalem


1045 - 1215Rm EA-06-05

Symposium 13Liquid Biopsy for Disease Diagnosis

Ali Asgar Saleem BhagatNational University of Singapore

Han Wei HouNanyang Technological University of Singapore

NUS ENGINEERING INDUSTRY DAY: FUTURE HEALTH TECHNOLOGYCo-organised with the Singapore Health Technologies Consortium (HealthTEC)

It is our great pleasure to invite you to this year’s NUS Engineering Industry Day. Building on last year’s Industry Day, the theme for this year is “Future Health Technology”. We will be bringing together partners from industry, government agencies and academia to discuss and develop strategic plan to drive Healthtech innovation and enterprise in Singapore.

The year’s event is specially held in conjunction with the 17th International Conference on Biomedical Engineering. As such, we are honoured to have Prof Abraham Lee (UCI) and Prof Paolo Dario (Scuola Superiore Sant’Anna) as Plenary Lecture speakers. Together with our local panellists, they will be able to examine pertinent issues regarding Future Health Technology. You are invited to visit our showcase of exciting technologies in Biofabrication, BioImagine, Biosensors and Medical Robotics and explore potential collaborations with NUS Engineering.

All registered ICBME delegates are invited to attend the NUS Engineering Industry Day.

Time Programme

1000 Event Registration and Refreshments

1030 Welcome by Thean Voon Yew, AaronDean of Faculty of Engineering, NUS

1045 Plenary Lecture 1:Abraham LeeSamueli School of Engineering, University of California, Irvine

1115 Plenary Lecture 2:Paolo DarioBiomedical Robotics and Director of the BioRobotics Institute,Sant’Anna School of Advanced Studies

1145 Panel Discussion:Overcoming the Healthcare Challenges of Our Time with Next Generation Engineering

Panellists:1. Abraham Lee

Samueli School of Engineering, University of California, Irvine

2. Paolo Dario Biomedical Robotics and Director of the BioRobotics Institute, Sant’Anna School of Advanced Studies

3. Erik Trip General Manager, BIOTRONIK Asia Pacific Pte Ltd, Singapore

4. Sandeep Chalke Managing Director, Chalk Consultancy Pvt. Ltd

5. Siew Hwa Ong Director & Chief Scientist, Acumen Research Laboratories Pte Ltd

Moderator:Dean HoProfessor and Head, Department of Biomedical Engineering

1230 Lunch and Exhibition

Programme


GENERAL INFORMATIONConference VenueNational University of SingaporeFaculty of EngineeringBlock EA, 9 Engineering Drive 1Singapore 117575

Registration Hours Registration counters are located at the Foyer on Level 1, and opening hours are as follows:

BadgeUpon registration, you will receive your badge and conference materials. It is mandatory that participants wear their badges at all times at the conference venue.

LanguageThe o¦cial language of the Conference is English. No translation will be provided.

Internet AccessComplimentary WIFI is available within the Conference venue. It is designed for web browsing and checking web-based email and not designed for accessing VPN or downloading of large files. To connect to the WIFI network, please follow the steps below:

1. Under Wi-Fi networks, select “NUS_Guest”2. In your browser, click on “Event Login”3. Enter U4P52C for the Wi-Fi Pin and the verification code shown and click ‘I agree to the terms of use and

proceed’.

Lunch and Co©ee BreaksLunch and co£ee breaks are served daily at the Foyer on Level 1. Please refer to the Scientific Programme for the time of each break.

Speakers’ Ready RoomAll speakers and presenters are requested to proceed to the Speakers’ Ready Room (Level 2, Rm EA 02-14) to submit your PowerPoint slide presentations. Please note that all presentation files should be submitted at least 4 hours prior to your session.

Date Opening Hours (Hrs)

Monday, 9 December 0800 - 1700

Tuesday, 10 December 0800 - 1700

Wednesday, 11 December 0800 - 1700

Thursday, 12 December 0800 - 1700

Date Opening Hours (Hrs)





GENERAL INFORMATIONPoster PresentationPosters are presented at the Foyer on Level 2 throughout the Conference. Poster judging sessions will take place during lunch on 9 December and 11 December. Poster authors are encouraged to stand by their posters during this period.

Poster authors are to note the poster set-up and dismantling schedule below. Kindly remove your posters within the specific dismantling period. Posters that are not removed on time will be disposed without further notice.

Certificates of Attendance and PresentationCertificates of Attendance are available for collection at the registration counters located on Level 1 from Tuesday, 10 December 2019, 1400 hrs onwards.

Authors may collect their Certificates of Presentation from the Speakers’ Ready Room (Level 2, Rm EA-02-14) from Tuesday, 10 December 2019, 1400 hrs onwards.

Welcome Reception, 9 December 2019All faculty and registered delegates are invited to join us for an evening of networking, drinks and light refreshments to kick o£ ICBME 2019 from 1730 - 1900 hrs. Admission is by conference badge only.

Lab Tours, 10 December 2019Delegates are welcome to join tours to the following labs on the afternoon of Tuesday, 10 December:1. Mechanobiology Institute & MechanoBioEngineering Lab2. Institute for Health Innovation and Technology (iHealthTech)3. Centre for Additive Manufacturing4. Advanced Robotics Centre

Please approach our registration sta£ for more information and to sign up.

Gala Dinner, 11 December 2019 (Ticketed Event)We invite all delegates to an evening of excellent food, fine wine, great company and conversations at the ICBME 2019 Gala Dinner on Wednesday, 11 December 2019 from 1830 - 2130 hrs. This highly-anticipated networking event will be held at Faber Peak Singapore - the only top-of-hill event location in Singapore with a bird’s eye view of the harbour, Sentosa and the city skyline.

Please note that admission is strictly by ticket only. Limited tickets are available for sale at the registration counter, on a first-come-first-served basis. Ticket sale closes at 1400 hrs on 9 December 2019. Please note that only cash payment is accepted onsite.

Complimentary shuttle service to and fro Faber Peak Singapore will be provided. Please check with our sta£ at the registration counter for the shuttle service schedule.

Liability and InsuranceThe Conference Organisers and Secretariat cannot accept liability for personal accidents or loss of or damage to private property of participant and accompanying persons. Participants are advised to take up their own travel and health insurance for their trip.

Conference SecretariatFor post-Conference enquiries and information, please contact the Conference Secretariat at [email protected].

Date Set-up Period (Hrs) Dismantling Period (Hrs)






VENUE FLOOR PLAN ATBLOCK EA, FACULTY OF ENGINEERING, NUS

Block EA Level 1, NUS, Faculty of Engineering

Activity Location

Registration Level 1, Foyer

Lunch and Co£ee Breaks Level 1, Foyer

Posters Level 2

Exhibition Showcase Level 1, Foyer

Speakers Room Level 2, Rm EA-02-14

Opening and Closing Ceremony Level 1, Lecture Theatre 7A

Plenary Lectures Level 1, Lecture Theatre 7A

Oral Sessions & Symposia Level 1, Lecture Theatre 7ALevel 1, Engineering AuditoriumLevel 2, Rm EA-02-11Level 6, Rms EA-06-03 / 04 / 05

Young Investigators Awards 2019 Level 2, Rm EA-02-11

Engineering

AuditoriumICBME 2019

Santec Corporation

Springer

Polaris Science Pte Ltd

HealthTEC

World Congress 2021 / BES / IFMBE

12345

Lift Lobby

Lift Lobby

Oral Sessions& Symposia:

Rm EA-06-05


Rm EA-06-04


Rm EA-06-03

VENUE FLOOR PLAN ATBLOCK EA, FACULTY OF ENGINEERING, NUSBlock EA Level 2, NUS,Faculty of Engineering

Block EA Level 6, NUS,Faculty of Engineering

SpeakersRoom:

Rm EA-02-14

Oral Sessions &Symposia:

Rm EA-02-11

Lift Lobby

Lift Lobby

Posters


PROGRAMME-AT-A-GLANCETIME MONDAY, 9 DECEMBER, Day 1

VENUE LECTURE THEATRE 7A

ENGINEERING AUDITORIUM EA-02-11 EA-06-03 EA-06-04 EA-06-05

0800-

0900

RegistrationLevel 1, Foyer

0900-

0930

Opening Ceremony & AddressLecture Theatre 7A

0930-

1015

Conference Lecture 1Zhong Lin Wang

Session Chair: James GohLecture Theatre 7A

1015-

1045

Co£ee BreakLevel 1, Foyer

1045-

1215Session 1.1

Cell Mechanics 1

Session 1.23D Bioprinting & Regenerative

Medicine

Session 1.3 Smart Devices

Session 1.4Human Disease

Diagnosis & Therapy 1

Special Symposium 1: Rehabilitation

Robotics

Special Symposium 2: Bioelectronics

1215-

1315

Lunch (Poster Viewing & Judging)Foyer, Levels 1 & 2

1315-

1400

Plenary Lecture 1Yoshinobu Baba

Session Chair: Siew Lok TohLecture Theatre 7A

1400-

1530Session 1.5

Cell Mechanics 2

Session 1.6Biomaterials & Regenerative

Medicine

Session 1.7Soft Robotics 1

Session 1.8Human Disease

Diagnosis & Therapy 2

Special Symposium 3:

Biomedical Nanotechnology


Mechanobiology

1530-

1600


1600-

1730Session 1.9

Cell Mechanics 3Session 1.10

Soft Robotics 2

Session 1.11 Bio-Micro/

Nanotechnologies 1

Session 1.12 BME Education


Wearable Sensing Technology


Exosomes

1730-

1900

Welcome ReceptionNUS Engineering

End of Day 1

PROGRAMME-AT-A-GLANCETIME TUESDAY, 10 DECEMBER, Day 2



0800-

0830


0830-

1000

Session 2.1Sports & Clinical Biomechanics

Session 2.2Computational &

Modeling 1

Session 2.3Young

Investigator Awards

Session 2.4Bio-Micro/

Nanotechnologies 2


Cardiac Mechanics 1

Special Symposium 8:Reproductive

Bioengineering 1

1000-

1030


1030-

1045

NUS Engineering Industry DayOpening Remarks by Aaron TheanDean, Faculty of Engineering, NUS

Lecture Theatre 7A

1045-

1130

Plenary Lecture 2Abraham Lee

Session Chair: Leo Hwa LiangLecture Theatre 7A

1130-

1215

Plenary Lecture 3Paolo Dario

Session Chair: Raye YeowLecture Theatre 7A

1215-

1300

Panel Session:Future Health Technology

Lecture Theatre 7A

1300-

1400

Lunch (Poster Viewing)Foyer, Levels 1 & 2

1400-

1730Lab Tours

1900 End of Day 2


PROGRAMME-AT-A-GLANCETIME WEDNESDAY, 11 DECEMBER, Day 3



0800-

0930


0930-

1015

Conference Lecture 2Sir Konstantin Novoselov

Session Chair: Chwee Teck LimLecture Theatre 7A

1015-

1045


1045-

1215

Session 3.1Cardiovascular Biomechanics 1

Session 3.2Computational &

Modeling 2

Session 3.3Wearable Robotics


Nanotechnologies 3

Session 3.5Bioimaging & Biosignals 1


Cardiac Mechanics 2

1215-

1315

Lunch (Poster Viewing & Judging)Foyer, Levels 1 & 2

1315-

1400

Plenary Lecture 4Walter Herzog

Session Chair: James GohLecture Theatre 7A

1400-

1530


Session 3.7Clinical

Engineering 1

Session 3.8Prosthetics &

Assistive Devices


Nanotechnologies 4


Special Symposium 10: Reproductive

Bioengineering 2

1530-

1600


1600-

1730


Session 3.12Clinical

Engineering 2

Session 3.13Surgical &

Therapeutic Devices


Nanotechnologies 5


Surgical Robotics

Special Symposium 12: Organ-on-Chip

1730-

2030

Gala DinnerFaber Peak Singapore

End of Day 3

PROGRAMME-AT-A-GLANCETIME THURSDAY, 12 DECEMBER, Day 4



0800-

0930


0930-

1015

Plenary Lecture 5Beng Chin Ooi

Session Chair: Martin BuistLecture Theatre 7A

1015-

1045


1045-

1215


Session 4.2Bioelectronics & Electroceuticals

Session 4.3Neuroengineering/Neurotechnology

Session 4.4Big Data,

Healthcare Analytics & AI

Session 4.5Musculoskeletal Biomechanics


Liquid Biopsy for Disease Diagnosis

1215-

1300

Closing Ceremony & Award PresentationLecture Theatre 7A

1300-

1400

Farewell LunchFoyer, Level 1

End of Conference


TIME MONDAY, 9 DECEMBER, Day 1

VENUE LECTURE THEATRE 7A ENGINEERING AUDITORIUM EA-02-11 EA-06-03 EA-06-04 EA-06-05

0800 - 0900 Registration

0900 - 0930 Opening Ceremony & AddressLecture Theatre 7A

0930 - 1015 Conference Lecture 1Nanogenerators for Powering Implantable Medical Devices and Self-powered Sensors Zhong Lin WangGeorgia Institute of Technology; Beijing Institute of Nanoenergy and NanosystemsChinese Academy of Sciences Session Chair: James GohLecture Theatre 7A

1015 - 1045 Co£ee Break

1045 - 1215Session 1.1Cell Mechanics 1

Session Chairs:Masahiro SokabeNagoya University Graduate School of MedicineKazuaki NagayamaIbaraki University

1045 - 1115KEYNOTE Mechanosensitive Ion Channels Play a Crucial Role in Substrate Rigidity Sensing in Mesenchymal Stem CellsMasahiro SokabeNagoya University Graduate School of Medicine

1115 - 1130Cyclic Stretch-Induced Mechanical Stress to the Cell Nucleus Improves the Ultraviolet Radiation Resistance in CellsKazuaki NagayamaIbaraki University

1130 - 1145Identifying Cell Mechanical Changes in Cancer InvasionHuabing YinUniversity of Glasgow

1145 - 1200Hydrostatic Pressure Induces Magnitude-Dependent Changes in Endothelial Cell BehaviorDaisuke YoshinoTohoku University

Session 1.23D Bioprinting & Regenerative Medicine

Session Chairs:Y. Shrike ZhangHarvard Medical SchoolAthina MarkakiUniversity of Cambridge

1045 - 1115KEYNOTE 3D Bioprinting for Tissue and Tissue Model FabricationY. Shrike ZhangHarvard Medical School

1115 - 1130Hierarchical 3D Printable Vascular Networks for Tissue EngineeringAthina MarkakiUniversity of Cambridge

1130 - 1145Generation of Vascular Invasion Model of Colorectal Cancer with the Three-Dimensional Culture MethodKiminori YanagisawaGraduate School of Medicine, Osaka University

1145 - 1200Bioprinting of Human Endometrial Stem Cell (eMSC) on 3D Melt Electrospun Meshes Induce Anti-Inflammatory Response Following Tissue Regeneration in a Mouse ModelKallyanashis PaulMonash University

1200 - 1215Stereolithography (SLA) 3D Printed Templates for Engineering Perfusable Biomimetic Vasculatures in Alginate-Gelatin HydrogelTerry ChingSingapore University of Technology and Design

Session 1.3 Smart Devices

Session Chairs:Wei GaoCalifornia Institute of TechnologyAaron Raymond SeeSouthern Taiwan University of Science and Technology

1045 - 1115KEYNOTE Wearable Sweat Sensors for Personalized Health MonitoringWei GaoCalifornia Institute of Technology

1115 - 1130Obstacle Detector and Qibla Finder for Visually Impaired Muslim CommunityAaron Raymond SeeSouthern Taiwan University of Science and Technology

1130 - 1145Development of Wearable Device for Blood Pressure Estimation Based on Pulse Rate Measurement: Feasibility StudySoshi KuroeTohoku University

1145 - 1200Smart Landmark Navigation Cane for People with Visual Impairment (PVI)Wai Ming KongNanyang Polytechnic

Session 1.4Human Disease Diagnosis & Therapy 1

Session Chairs:I-Ming HsingHong Kong University of Science and TechnologyJasvinder SinghUniversity of Alabama at Birmingham

1045 - 1115KEYNOTE Nucleic Acid Based Bioengineering and Organic Electrochemical Transistor Based Flexible BioelectronicsI-Ming HsingHong Kong University of Science and Technology

1115 - 1130Lupus A©ects Total Hip Arthroplasty OutcomesJasvinder SinghUniversity of Alabama at Birmingham

1130 - 1145Adopting a Three-Dimensional Beads Array Design for Quick Isolation of Circulating Tumor CellsSung-Chi TsaiLifecode Biotech Co., Ltd.

1145 - 1200Cryocompression for Preventing Chemotherapy-Induced Peripheral NeuropathyAishwarya BandlaNational University of Singapore

1200 - 1215Prediction of Evolving ReadmissionRisk in Heart Failure Using MultivariateClinical Time Series DataPavitra KrishnaswamyInstitute for Infocomm Research

Special Symposium 1:Rehabilitation Robotics

Session Chairs:Raye Yeow National University of Singapore Haoyong Yu National University of Singapore

1045 - 1100Robot-Assisted Therapy Improves Task and Motor Performance in the Upper Extremities of Chronic Stroke PatientsHsiu-Yun HsuNational Cheng Kung University

1100 - 1115Toward the Smart Soft Robotic Hand for Stroke RehabilitationZheng LiChinese University of Hong Kong

1115 - 1130A©ordable Assistive Devices for Movement DisabilitySujatha SrinivasanIndian Institute of Technology Madras

1130 - 1145EsoGlove - Soft Robotics for Hand RehabilitationChen Hua,Raye YeowNational University of Singapore

1145 - 1200Rehabilitation RoboticsVincent CrocherUniversity of Melbourne

1200 - 1215A Robotic Platform Integrated with FES for Gait RehabilitationHaoyong YuNational University of Singapore

Special Symposium 2:Bioelectronics

Session Chair:John Ho National University of Singapore

1045 - 1115KEYNOTEWearable Sensors and Nanogenerators for Healthcare ApplicationsChengkuo Vincent LeeNational University of Singapore

1115 - 1130Wireless Technologies for Bioelectronic Therapies and DiagnosticsJohn HoNational University of Singapore

1130 - 1145Soft, Wireless and Battery Free Sensors and Photonics for Broad Application in the Assessment and Stimulation of Biological SystemsPhilipp GutrufUniversity of Arizona

1145 - 1200Applications of Wireless Technology for BiomedicineSanghoek KimKyung Hee University

1200 - 12153D Printing of Functional Electronics and Ingestible Biomedical DevicesYong Lin KongUniversity of Utah

1215 - 1230Body Area Network: Connecting Things Together Around the Human BodyJerald YooNational University of Singapore

1215 - 1315 Lunch (Poster Viewing & Judging)

SCIENTIFIC PROGRAMME




1315 - 1400 Plenary Lecture 1Nanobiodevices, Quantum Technology, and AI for Precision Medicine and Future Healthcare Yoshinobu BabaNagoya University Session Chair: Toh Siew LokLecture Theatre 7A

1400 - 1530 Session 1.5 Cell Mechanics 2

Session Chairs:Pak Kin WongPenn State UniversityJyothsna VasudevanSingapore University of Technology and Design

1400 - 1430KEYNOTE Single Cell Biosensors for Dynamic Multigene Analysis in Complex Tissue EnvironmentsPak Kin WongPenn State University

1430 - 1445Production of Extracellular Matrix Mimic with Tunable Sti©ness and Its Use for Cancer-On-a-Chip ApplicationsJyothsna VasudevanSingapore University of Technology and Design

1445 - 1500Increased Hydrostatic Pressure A©ects Vascular Endothelial Cell BehaviorSatomi HiroseTohoku University

1500 - 1515Emerging Oscillation in Confined Collective Cell Motion Due to Geometry-Defined PolarizationJing YuNanyang Technological University of Singapore

1515 - 1530Initial Metastatic Pattern of Three-Dimensional Bladder Multicellular Tumor Spheroid at Heterogeneous Matrix InterfaceTing-Yuan TuNational Cheng Kung University

Session 1.6Biomaterials & Regenerative Medicine

Session Chairs:Liren WangShanghai Sixth People’s HospitalHuyen PhanThe University of Sydney

1400 - 1415Application of Umbilical Cord for Tendon RegenerationLiren WangShanghai Sixth People’s Hospital

1415 - 1430Extracellular Vesicles as the Next Generation TherapeuticsHuyen PhanThe University of Sydney

1430 - 1445Comparative in Vivo Evaluation of Perivascular Silk Fibroin Microneedle Meshes for Inhibiting Neointima FormationJiyong LeeYonsei University

1445 - 1500Influence of Surface Modification of Polystyrene Using Spectrum-Controlled UV Radiation on Mouse Embryonic Stem Cell CultureYuma YamanoiKeio University


Session Chairs:Cecilia LaschiScuola Superiore Sant’AnnaBenjamin AngNational University of Singapore

1400 - 1430KEYNOTE Soft Robotics in Biomedical ApplicationsCecilia LaschiScuola Superiore Sant’Anna

1430 - 14453D Printed Soft Pneumatic Actuators with Intent Sensing for Hand Rehabilitative ExoskeletonsBenjamin AngNational University of Singapore

1445 - 1500Novel Autonomous Magnetic Actuated Endoscope for Single Port SurgeryTruman ChengThe Chinese University of Hong Kong

1500 - 1515Sensorized Soft Hands for Enhanced Grasping ApplicationsMay KhinNational University of Singapore

Session 1.8Human Disease Diagnosis & Therapy 2

Session Chairs:Nicholas, Rui Yuan HoAgency for Science, Technology and ResearchHoward DoongLifecode Biotech Co., Ltd.

1400 - 1415Modular DNA-Enzyme Switches for Sensitive, Equipment-Free, and Visual Molecular DiagnosticsNicholas, Rui Yuan HoAgency for Science, Technology and Research

1415 - 1430Using a Pneumatic Microfluidic Chip with Enhanced 3D Mixing Capability to Increase the Isolation and Capture E¯ciency of Circulating Tumor CellsHoward DoongLifecode Biotech Co., Ltd.

1430 - 1445Subtyping of Circulating Exosome-Bound Amyloid B Reflects Brain Plaque DepositionCarine LimInstitute for Health Innovation & Technology

1445 - 1500A Path toward Safer Chelation Therapy: Developing a Wearable Microscale-Based Ex Vivo Device for the Removal of Toxic Excess Iron from PlasmaJad ToumaOregon State University

1500 - 1515A Real Time Analysis of PPG Signal to Measure the Hemoglobin ConcentrationShankarnath SuthakaranUniversity of Ruhuna

Special Symposium 3:Biomedical Nanotechnology

Session Chair:James Kah National University of Singapore

1400 - 1415Engineering Nanoplasmonic Materials for Optofluidic Biosensors towards Personalized MedicinePengyu ChenAuburn University

1415 - 1430Amyloidosis Mitigation – a New Frontier at the Bio-Nano InterfacePu Chun KeMonash University; Fudan University

1430 - 1445Metal Nanoparticle Radiosensitization for Improving RadiotherapyIvan KempsonUniversity of South Australia

1445 - 1500Sensing While Heating in a CellMadoka SuzukiOsaka University

1500 - 1515Acoustic Enhancement of Intracellular Delivery for Ex Vivo Autologous Cell TherapeuticsLeslie YeoRoyal Melbourne Institute of Technology (RMIT)

1515 - 1530Peptide Modification of Ferritin Nanocages for Intracellular Cholesterol Reduction in AtherosclerosisSamyukta RavishankarNanyang Technological University of Singapore

Special Symposium 4:Mechanobiology

Session Chair:Guy Genin Washington University in St Louis

1400 - 1430KEYNOTE Cryoprotectant Enables Structural Control of Porous Sca©olds for Exploration of Cellular Mechano-Responsiveness in 3DYanan DuTsinghua University

1430 - 1445Myosin-Independent Regulation of Wavy Cell Structure and Nuclear Strain TransferPen-Hsiu Grace ChaoNational Taiwan University

1445 - 1500Thermal-Disrupting Interface Inducing Survival Dichotomy of Bacteria and Host Cells for Accurate Topical Antibacterial TherapyBenhui HuNanjing Medical University

1500 - 1515Hypertension Meets Osteoarthritis: A Revisit to Vascular AetiologyChunyi WenHong Kong Polytechnic University

1530 - 1600 Co£ee Break





1600 - 1730 Session 1.9Cell Mechanics 3

Session Chairs:Guy GeninWashington University In St LouisFeng XuXi’An Jiaotong University

1600 - 1630KEYNOTE Electrostatic Switching of Nuclear Basket Conformations Provides a Potential Mechanism for Nuclear MechanotransductionGuy GeninWashington University In St Louis

1630 - 1700KEYNOTE Engineering of Cell Mechanical MicroenvironmentFeng XuXi’An Jiaotong University

1700 - 1715Segmentation of Endothelial Cell Growth in a Swirling Well Plate Allows Investigation of the Shear-Dependent Release of Soluble MediatorsKuin Tian PangImperial College London

1715 - 1730E©ect of Static Compression on Invasion Process of Malignant Melanoma Cells Within in Vitro Three-Dimensional Culture.Takashi MorikuraKeio University


Session Chairs:Ajinkya BhatNational University of SingaporeAhmed Khalil KhanNational University of Singapore

1600 - 1615 Mechanical Programming of Soft Pneumatic Actuators Using Embedded EndostructuresAjinkya BhatNational University of Singapore

1615 - 1630 Design, Fabrication and Characterization of a Modular Soft Robotic Arm with 3 Degrees of Freedom Ahmed Khalil KhanNational University of Singapore

1630 - 1645 Shape Shifting Actuators with Controllable Constraints Chao-Yu ChenNational University of Singapore

1645 - 1700 A Novel Modular Soft Robotic Arm towards Assisting Activities of Daily LivingXinquan Liang National University of Singapore

1700 - 1715 Multifunctional Soft Robots Based on Durian Thorn-Inspired Actuators Luis Carlos Hernandez Barraza National University of Singapore

Session 1.11Bio-Micro/Nanotechnologies 1

Session Chairs:Noah Riandiputra SundahNational University of SingaporeTomohiro SekiguchiShibaura Institute of Technology

1600 - 1615DNA Sequence-Topology Assembly for Multiplexed Profiling (STAMP) of Subcellular Protein DistributionNoah Riandiputra SundahNational University of Singapore

1615 - 1630Smooth Microfluidic Media Recirculation Using Sinusoidal Peristaltic Action of Refreshable Braille Actuator ArrayTomohiro SekiguchiShibaura Institute of Technology

1630 - 1645Microfluidic Perfusion Array: Applications in Oral Mucosal Drug Permeation StudiesGiridharan MunirajNational University of Singapore

Session 1.12BME Education

Session Chairs:Shankar KrishnanWentworth Institute of TechnologyMitsuo UmezuWaseda University

1600 - 1630KEYNOTEDesigning a Medical Imaging and Optics Track in an Undergraduate Biomedical Engineering Program Shankar KrishnanWentworth Institute of Technology

1630 - 1700KEYNOTE Biomedical Engineering Education Program for Graduate Students at TWins, Waseda UniversityMitsuo UmezuWaseda University

1700 - 1715Internet of Things Education for Applications in Medicine and Healthcare Ratko MagjarevicUniversity of Zagreb

1715 - 1730Driving Healthcare Innovation, the SUTD WayXiaojuan KhooSingapore University of Technology and Design

Special Symposium 5:Wearable Sensing Technology

Session Chairs:Benjamin Tee National University of Singapore Joo Chuan Yeo National University of Singapore

1600 - 1630 KEYNOTE Stretchable Gold Nanowire Electrode – a New Wearable Electrochemical Biosensing PlatformWenlong ChengMonash University

1630 - 1700 KEYNOTE Skin – The Ultimate Window to Your Health Zee UptonInstitute of Medical Biology

1700 - 1715 Multi-Physical Modelling of Soft PDMS- Liquid Metal Interdigitated Capacitors Sensor Zhuangjian Liu Institute of High Performance Computing

1715 - 1730Stretchable Smart Device Using Liquid-State ElectronicsHiroki Ota YokohamaNational University

Special Symposium 6:Exosomes

Session Chairs:Huilin Shao National University of Singapore Wojtek Chrzanowski The University of Sydney Nano Institute

1600 - 1630KEYNOTE Exosomes and Mimetic Technologies for TherapeuticsYong Song GhoPohang University of Science and Technology

1630 - 1645Extracellular Vesicles in Cross Species Communication and Cancer ProgressionSuresh MathivananLa Trobe University Australia

1645 - 1700High-Fidelity, Nanoscale Characterization of Extracellular VesiclesWojciech ChrzanowskiThe University of Sydney

1700 - 1715Label-Free Isolation of Circulating Exosomes from Whole Blood Using Centrifugal ForcesHan Wei HouNanyang Technological University of Singapore

1715 - 1730MSC Exosome for Cell-Free Regenerative Joint Therapy: Escalating towards Clinical ApplicationWei Seong TohNational University of Singapore

1730 - 1745Nanosensor Technologies for Molecular Analyses of Circulating ExosomesHuilin ShaoNational University of Singapore

1730 - 1900 Welcome Reception

End of Day 1



TIME TUESDAY, 10 DECEMBER, Day 2

VENUE LECTURE THEATRE 7A ENGINEERING AUDITORIUM EA-02-11 EA-06-03 EA-06-04 EA-06-050800 - 0830 Registration0830 - 1000 Session 2.1

Sports & Clinical Biomechanics

Session Chairs:Kentaro TakahashiKanto Gakuin UniversityMinato KawaguchiKanto Gakuin University

0830 - 0845Biomedical Signal Analysis of “Nihon Kendo Kata”Kentaro TakahashiKanto Gakuin University

0845 - 0900Analysis of Respiration Pattern and Frontal Brain Activity During the Aiming Period in Rifle ShootingMinato KawaguchiKanto Gakuin University

0900 - 0915Analysis of the Muscle Activity and the 3-Direction Force During the Constant Work Rate PedalingAtsushi IwashitaYamato University

0915 - 0930Influence of Compressive Preloading on Range of Motion and Endplate Stresses in the Cervical Spine During Flexion/ExtensionSrikanth SrinivasanVit University, Chennai Campus

Session 2.2Computational & Modeling 1

Session Chairs:Desmond Y.R. ChongSingapore Institute of TechnologyLingyun ZhangBeijing University of Technology

0830 - 0845Biomechanical Analysis of Bone-Prosthesis Interface Micromotion for Cementless Talar Component Fixation in Preventing Aseptic Loosening FailureDesmond Y.R. ChongSingapore Institute of Technology

0845 - 0900Identifying Hip Fracture-Related Critical “Weak-Links” Within the Femur by in Vivo microMRI-Based Finite Element AnalysisLingyun ZhangBeijing University of Technology

0900 - 0915Dynamic 3D Imaging of Articular Cartilage under Repetitive Compression Measured by Phase-Contrast X-Ray CTTakako OsawaKindai University

0915 - 0930An Inverse Finite Element Method to Measure In-Vivo Biomechanical Properties of Human IrisSatish Kumar PandaNational University of Singapore

Session 2.3Young Investigator Awards

Session Chairs:Viveka KalidasanNational University of SingaporeKento YamagishiWaseda University

0830 - 0845Wirelessly Responsive and Highly Pliant Sutures for Post-Operative Wound MonitoringViveka KalidasanNational University of Singapore

0845 - 0900Tissue-Adhesive and Wireless Light-Emitting Device for Photodynamic Cancer TherapyKento YamagishiWaseda University

0900 - 0915Mechanical Loading Promotes the Expansion of Primitive Osteoprogenitors and Organizes Matrix and Vascular Morphology in Long Bone DefectsChao LiuSouthern University of Science and Technology

0915 - 0930Wireless Biosensing System for Simplified Salivary Uric Acid Self-CheckYuki IkemotoMeiji University

0930 - 0945CLeONs: Contact Lens-Coated Oxygen Nanosensors for Rapid pO2 Sensing in the Post Lens-Tear FilmThanuja MySiddaganga Institute of Technology, Tumkur

Session 2.4Bio-Micro/ Nanotechnologies 2

Session Chairs:Takehiko KitamoriThe University of TokyoYoshitaka NakanishiKumamoto University

0830 - 0900KEYNOTE Design and Fabrication Methods of Micro/Nanofluidics for Biomedical Applications: Example for Cytokine Analysis from Single Living B CellTakehiko KitamoriThe University of Tokyo

0900 - 0915Three-Dimensional Multiscale Surface Processing Methods to Create Bio-Inspired SurfaceYoshitaka NakanishiKumamoto University

0915 - 0930Controlled Oxygen Tension Regulates Vascular Endothelial Cell Migration through P21-Activated Kinase SignalingYugo TabataTohoku University

0930 - 0945LEGO®-Like Modular Magnetic Digital Microfluidics with Programmable Liquid Path for Bioanalytical AssaysPojchanun KanitthamniyomNanyang Technological University of Singapore

0945 - 1000Computational Fluid Dynamics Modeling for Lateral Migration of Extracellular Vesicles in Spiral Inertial MicrofluidicsSheng Yuan LeongNanyang Technological University of Singapore

Special Symposium 7:Cardiac Mechanics 1

Session Chair:Choon Hwai Yap National University of Singapore

0830 - 0900KEYNOTE Patient Specific Factors Governing the Success of Trans-Catheter Aortic ValvesLakshmi DasiThe Ohio State University

0900 - 0915Development of a Magnetically Levitated Extra-Corporeal Ventricular Assist Device in ChinaPo-Lin HsuMagassist Inc.

0915 - 0930Electromechanical Modelling of the Left Ventricle to Investigate Mechanisms of Myocardial Infarct ExtensionChin Neng LeongUniversity of Malaya

Special Symposium 8:Reproductive Bioengineering 1


0830 - 0845Oviduct-on-Chip Platform for in Vitro Bovine Embryo ProductionSéverine Le GacUniversity of Twente

0845 - 0900Mimicking Uterine to Culture Mouse EmbryosQi GuInstitute of Zoology

0900 - 0915Feeding Baby in Utero: An Imaging and Computational Modelling Study of How Uterine Artery Blood Flow Impacts Placental FunctionAlys ClarkUniversity of Auckland

0915 - 0930Analysis of the Placenta Biomechanical Characteristics for Detection of Intrauterine Growth RestrictionChoon Hwai YapNational University of Singapore

0930 - 0945Bioengineered Cell Based Nanostructured Strategies in Urogynecology: New Era in ProlapseShayanti MukherjeeHudson Institute of Medical Research

1000 - 1030 Co£ee Break1030 - 1045 NUS Engineering Industry Day:

Opening Remarks by Aaron TheanDean, Faculty of Engineering, NUSLecture Theatre 7A

1045 - 1130 Plenary Lecture 2Microfluidic Precision Medicine – Processing the Minimal Representative Unit for Top-down Diagnostics and Bottom-up TreatmentAbraham LeeUniversity of California, Irvine Session Chair: Hwa Liang LeoLecture Theatre 7A

1130 - 1215 Plenary Lecture 3Frontiers of Biorobotics and Bionics Science and EngineeringPaolo DarioSant’Anna School of Advanced Studies ItalySession Chair: Raye YeowLecture Theatre 7A

1215 - 1300 Panel Session:Future Health TechnologyLecture Theatre 7A

1300 - 1400 Lunch

1400 - 1730 Lab Tours

End of Day 2



TIME WEDNESDAY, 11 DECEMBER, Day 3

VENUE LECTURE THEATRE 7A ENGINEERING AUDITORIUM EA-02-11 EA-06-03 EA-06-04 EA-06-050800 - 0930 Registration

0930 - 1015 Conference Lecture 2Materials in the FlatlandSir Konstantin NovoselovNobel Prize in Physics, 2010National University of Singapore Session Chair: Chwee Teck LimLecture Theatre 7A

1015 - 1045 Co£ee Break1045 - 1215 Session 3.1

Cardiovascular Biomechanics 1

Session Chairs:Xiao XuImperial College LondonKyehan RheeMyongji University

1045 - 1115KEYNOTE Multi-Level Modelling of Thrombolysis in Ischemic StrokeXiao XuImperial College London

1115 - 1130E©ects of Viscoelastic Property of Atherosclerotic Plaque on Wall Motion Using Artery PhantomsKyehan RheeMyongji University

1130 - 1145Finite Element Simulation of the Mitral Heart Valve ClosureKamran HassaniIslamic Azad University,Science and Research Branch

1145 - 1200Impact of Superhydrophobicity on Prosthetic Valve Hemodynamics and TurbulenceHoda HatoumThe Ohio State University

1200 - 1215Ex Vivo Assessment of Right Ventricular Hemodynamics After Bicuspidization Repair to Treat Severe Functional Tricuspid Regurgitation: A Stereo-Scopic PIV StudyMabel Yen Ngoc NguyenNational University of Singapore

Session 3.2Computational & Modeling 2

Session Chairs:Karthic AnbalakanNational University of SingaporeYoke Yin FooNational University of Singapore

1045 - 1100Determining the E¯cacy of Drug Coated Balloon Therapy through In-Silico ModellingKarthic AnbalakanNational University of Singapore

1100 - 1115Understanding the Flow Patterns of Beating Embryonic Heart via Computational Fluid Dynamics SimulationYoke Yin FooNational University of Singapore

1115 - 1130Construction of Predictive Model of Patency in Venous Graft Based on Image Feature of Anastomotic Wall Shear Stress under Coronary Artery Bypass GraftBoyan MaoBeijing University of Technology

1130 - 1145A Numerical Study on the Aerodynamic Characteristics of Newborn with Severe Congenital LaryngomalaciaJuanya ShenShanghai Children’S Medical Center, Shanghai Jiao Tong University School of Medicine

1145 - 1200A Multi-Dimensional Approach to Investigate the E©ects of the Physiological Properties on the Aortic DissectionHamed KeramatiNational University of Singapore

1200 - 1215Development of Robust Amphiphilic Coating for Drug Coated BalloonHan Wei TohNational Heart Centre Singapore

1215 - 1230Electromechanics of Gastrointestinal Smooth MuscleSatish Kumar PandaNational University of Singapore

Session 3.3Wearable Robotics

Session Chairs:Nicholas ChengNational University of SingaporeTiana Miller-JacksonNational University of Singapore

1045 - 1100Assistive Soft Robotic Glove Stroke Rehabilitation Using EEG-Based Motor Imagery Brain-Computer Interface for Elderly Stroke PatientsNicholas ChengNational University of Singapore

1100 - 1115Development of a Soft Wearable Robotic Device for Gait AssistanceTiana Miller-JacksonNational University of Singapore

1115 - 1130Self-Wearing Glove with Bidirectional ActuatorsAzmall FraiszudeenAdvanced Robotics Centre/ National University of Singapore

1130 - 1145Towards Full Fabric Robotic Exoskeletons for the ShoulderRainier NatividadNational University of Singapore

1145 - 1200Application of Novel Graphite Flex Sensors in Closed-Loop Angle Feedback on a Soft Robotic Glove for Stroke RehabilitationAaron GohNational University of Singapore

1200 - 1215Clinical Trials for E¯cacy of Ankle Mobilization Using Soft Robotic Device for Immobile Stroke PatientsFan-Zhe LowNational University of Singapore


Session Chairs:Kohji MitsubayashiTokyo Medical and Dental UniversityMasaki YamaguchiShinshu University

1045 - 1115KEYNOTE Gas-Phase Biosensors (Bio-Sni©er & Sni©-Cam) for Human Volatile ChemicalsKohji MitsubayashiTokyo Medical and Dental University

1115 - 1130Reaction Area-Enhanced Fibers Used for Knitting Based-BiosensorMasaki YamaguchiShinshu University

1130 - 1145On-Surface Antibody Immobilization and Rapid Immunoassay on a Microfluidic Chip.Adelina SmirnovaThe University of Tokyo

1145 - 1200Colorimetric Analysis of Hemoglobin on Laser Printed Microfluidic Paper-Based Analytical Devices (µPADs)Shizhao James NgSingapore University of Technology and Design

1200 - 1215MoS2-MWCNT Based Fluorometric Nanosensor for Exosome Detection and QuantificationMahnoush TayebiSingapore University of Technology and Design


Session Chairs:Yanling ChiA*STARYuxuan ZhouNanjing Medical University

1045 - 1100Tumor Localization in Ultrasound-Guided Liver RFA on SwineYanling ChiA*STAR

1100 - 1115A Data-Driven Algorithm for Interpretation of Surface Electromyograms During Functional Electrical Stimulation with Time Varient ParametersYuxuan ZhouNanjing Medical University

1115 - 1130Automatic Detection of Malignant Cells from Cervical Cancer Cytodiagnosis ImagesToshiyuki TanakaKeio University

1130 - 1145Classification of B-Cell Acute Lymphoblastic Leukemia Microscopic Images Using Crow Search AlgorithmBharanidharan NBannari Amman Institute of Technology

1145 - 1200Continuous vs. Discrete Decoding of Movement Intentions - Which Is Better for Control? Rosa So Institute for Infocomm Research

1200 - 1215Brain Activity Indexing via Network ClusteringYongcheng Yao The Chinese University of Hong Kong

Special Symposium 9:Cardiac Mechanics 2


1045 - 1115KEYNOTE Applicability of an Embryonic Vascular Growth Model in Paediatric Cardiovascular SurgeriesKerem PekkanKoc University

1115 - 1130Left Atrial Structure and Strains in Heart Failure with Reduced and Preserved Ejection FractionLiang ZhongNational Heart Centre Singapore, Duke-NUS Medical School

1130 - 1145Numerical Hemodynamics Models for Leaflet Thrombosis Estimation Post Valve-In-Valve ImplantationGil MaromTel Aviv University

1145 - 1200Hemodynamic E©ects of Conduit on Systemic-to-Pulmonary Shunt: A Numerical Study Using Virtual DesignJinlong LiuShanghai Children’S Medical Center, Shanghai Jiao Tong University School of Medicine

1200 - 1215Mechanical Environment in the Left Atrial Ligated Whole Embryonic Heart at HH25 and Comparison to Growth at HH28.Sheldon HoNational University of Singapore

1215 - 1315 Lunch (Poster Viewing & Judging)




VENUE LECTURE THEATRE 7A ENGINEERING AUDITORIUM EA-02-11 EA-06-03 EA-06-04 EA-06-051315 - 1400 Plenary Lecture 4

Reflections on Muscle ContractionWalter HerzogUniversity of CalgarySession Chair: James GohLecture Theatre 7A

1400 - 1530 Session 3.6Cardiovascular Biomechanics 2

Session Chairs:Yu ZhengNational University of SingaporeHadi WiputraNational University of Singapore

1400 - 1415Enforcing Incompressibility in Myocardium Motion Estimation from Ultrasound Images Using an Add-on Regularization LayerYu ZhengNational University of Singapore

1415 - 1430Cardiac Motion Estimation from Noisy Medical ImagesHadi WiputraNational University of Singapore

1430 - 1445Numerical Analysis for the Influence of Heart Disease on the Blood Flow Field in Left Ventricle: Influence of Mitral RegurgitationTsuyoshi TakadaTohoku University

1445 - 1500Development of Blood Vessel Model Made of Polyvinyl Alcohol Hydrogel Embedded with Flexible Pressure Distribution Sensor for in Vitro Evaluation of Endovascular DevicesTakeshi MoriwakiHirosaki University

1500 - 1515A Patient-Specific Hemodynamic Analysis of Modified Blalock-Taussig Shunt: with and Without Ligation of the Patent Ductus ArteriosusJiwen XiongShanghai Children’S Medical Center, Shanghai Jiao Tong University School of Medicine

1515 - 1530Hemodynamic Characteristics of the Pulmonary Artery in the Child with Pulmonary Hypertension Related to Congenital Heart Disease: A Numerical Study by Computational Fluid DynamicsLiping WangShanghai Children’S Medical Center, Shanghai Jiao Tong University School of Medicine

Session 3.7Clinical Engineering 1

Session Chairs:Kang-Ping LinChung-Yuan Christian UniversitySeng Sing TanNanyang Polytechnic

1400 - 1430KEYNOTE CE-IT Alarm Management Technology to Improve Alarm Fatigue and Precision Nursing Based on Physiological Monitor SignalsKang-Ping LinChung-Yuan Christian University

1430 - 1445Pilot Study -- Portable Evaporative Cooling System for Exercise-Induced HyperthermiaSeng Sing TanNanyang Polytechnic

1445 - 1500Development of a Hospitalized-Patient Monitoring System Using Medical Radar for Continuously and Remotely Monitors of Respiratory RateGuanghao SunThe University of Electro-Communications

1500 - 1515Usefulness of Ozone Water for Preventing Infection in Home CareKoichi UmimotoOsaka Electro-Communication University

Session 3.8Prosthetics & Assistive Devices

Session Chairs:Paula SilvaSUTD-MIT IDCLin MengTianjin University

1400 - 1415A New Approach for the Design of AFOsPaula SilvaSUTD-MIT IDC

1415 - 1430A Practical Gait Feedback System for Wearable Drop Foot Correction DevicesLin MengTianjin University

1430 - 1445Prototype of Measurement System for Clothing Pressures in the Spinal OrthosisSakamoto KojiKyusyu Institute of Technology

1445 - 1500A Low-Cost Force Myography Sensor for Upper Limb Prosthesis ApplicationAlok PrakashIndian Institute of Technology, Banaras Hindu University, Varanasi, India

1500 - 1515Development of a Novel Rollator with an Active Driving Chest Pad to Achieve the E©ectiveness of Walk AssitanceJian HuangKindai University


Session Chairs:Oliver HaydenTechnical University of MunichKenichi FunamotoTohoku University

1400 - 1430KEYNOTE Go with the FlowOliver HaydenTechnical University of Munich

1430 - 1445Oxygen-Dependent Migration of Breast Cancer Cell Is Altered by Cell-Cell Interaction with Vascular Endothelial CellsKenichi FunamotoTohoku University

1445 - 1500A Pump-Free Tricellular Blood-Brain Barrier On-a-Chip Model to Understand Barrier Property and Evaluate Drug ResponseYu FangSIMTECH

1500 - 1515Microscale-Based, Lamina-Plate Extracorporeal Blood Processing: A Platform for Advancing Personalized Medical TherapeuticsMatthew CoblynOregon State University

1515 - 1530 Large-Scale Integrated Platform for Digital Mass Culture of Adherent Cells Dae-Hyeong Kim Seoul National University


Session Chairs:Takeshi ShimotoFukuoka Institute of TechnologyKartik BalachandranUniversity of Arkansas

1400 - 1415Analysis of the Spheroid Morphological Characteristics Using Pseudo-Color Image ProcessingTakeshi ShimotoFukuoka Institute of Technology

1415 - 1430Two Photon Excited Fluorescence Microscopy Metrics Are Sensitive to Early Phenotypic Changes in Calcific Aortic Valve Disease in Vitro and Ex VivoKartik BalachandranUniversity of Arkansas

1430 - 1445Raman Signal Noise Removal Using Dual-Tree Complex Wavelet TransformTaresh Sarvesh SharanIndian Institute of Technology (BHU)

1445 - 1500Respiratory Motion Simulation of Lung by Deformable Image Registration and InterpolationJing ZouThe Chinese University of Hong Kong

1500 - 1515Development of Three-Dimensional Ultrasonic-Measurement-Integrated Blood Flow Analysis System : Analysis of Unsteady Flow in Flow Phantom in Geometry Reconstructed from Ultrasound MeasurementHirose KudoTohoku University

1515 - 1530fMRI-BOLD Response in Rat Brain Against Direct Motor Cortical Stimulation Zonghao Xin The University of Tokyo

Special Symposium 10:Reproductive Bioengineering 2


1400 - 1415Time-Dependent Material Properties of Mouse Cervical Tissue During PregnancyNicole LeeColumbia University

1415 - 1430Biaxial Active and Passive Mechanical Properties of Fibulin-5 Deficient Mice VaginaGabrielle ClarkTulane University

1430 - 1445The Fiber Architecture and Anisotropic Material Properties of the Human UterusShuyang FangColumbia University

1445 - 1500Role of Elastic Fibers in the Biaxial Passive and Active Properties of the Murine VaginaGabrielle ClarkTulane University

1500 - 1515Characterization of Biaxial Biomechanical Properties of Human Post-Menopausal Uterosacral Ligament – Importance of Collagen on Biomechanical AnisotropyElvis DansoTulane University

1515 - 1530Investigations Into the Biomechanics of the Cervical CerclageAlexa BaumerThe George Washington University

1530 - 1600 Co£ee Break




VENUE LECTURE THEATRE 7A ENGINEERING AUDITORIUM EA-02-11 EA-06-03 EA-06-04 EA-06-051600 - 1730 Session 3.11


Session Chairs:Jaryl NgNational Heart Centre SingaporeIan WongBrown University

1600 - 1615TAP vs DKC Stenting Technique: An Evaluation of Double Stenting Bifurcation Technique Thrombogenicity Using Metallic DES in an in Vitro Left Main Bifurcation ModelJaryl NgNational Heart Centre Singapore

1615 - 1630Collective Migration and the Epithelial-Mesenchymal Transition in Engineered MicroenvironmentsIan WongBrown University

1630 - 1645E©ect of Thin-Strut BRS vs Metallic DES on Stent Expansion in a Lesion ModelJaryl NgNational Heart Centre Singapore

1645 - 1700Virtual Operation of Chordae Transposition for Anterior Mitral Leaflet ProlapseHyunggun KimSungkyunkwan University

1700 - 1715Development of a Covered Stent to Reduce Membrane InfoldingGideon KumarInstitute of High Performance Computing

Session 3.12Clinical Engineering 2

Session Chairs:Ulrich BetzUniversity Medical Center of The Johannes Gutenberg University Mainz GermanyRyota ItoWaseda University

1600 - 1615Analysis of Human Body Motion: towards Comprehensive Pattern Recognition Techniques in the Processing of Measuring DataUlrich BetzUniversity Medical Center of The Johannes Gutenberg University Mainz Germany

1615 - 1630Development of Calcification Models for Investigating Fracturing Performances of Coronary Lesion Modification DevicesRyota ItoWaseda University

1630 - 1645Flow Inside Large Cerebral Aneurysm Models After the Deployment of “Flow Diverter” Stent: Influence of the Location of Aneurysms at the Internal Carotid ArteryKoichi HoshinoWaseda University

1645 - 1700What Evaluation Is Appropriate for Regulatory Use of Pediatric Medical Devices?Sara TakahashiWaseda University

Session 3.13Surgical & Therapeutic Devices

Session Chairs:Karupppasamy SubburajSingapore University of Technology and DesignKarupppasamy SubburajSingapore University of Technology and Design

1600 - 1615Design and Development of Multi-Directional Needle Stabilizer System for Image-Guided Biopsy ProceduresKarupppasamy SubburajSingapore University of Technology and Design

1615 - 1630RETRAB: A Novel Abduction and Traction Device for Reduction of Shoulder DislocationKarupppasamy SubburajSingapore University of Technology and Design

1630 - 1645Development of Surgical Navigation System Predicts and Visualizes Brain-Function Positions in an Awake Surgery for GliomaYuta NambuFuture University Hakodate

1645 - 1700Design and Development of a Hand-Held Automated Guidewire Threading Device for Endovascular InterventionsKarupppasamy SubburajSingapore University of Technology and Design

1700 - 1715Extracorporeal Treatment of Hyperuricemia via Enzymatic Functionalized Microchannel PlatePlatforms: Experiment and ModelingJaturavit PantakitcharoenkulOregon State University

1715 - 1730Design and Development of Safety Systems to Reduce Guidewire Retention in Central Venous Catheterization ProcedureKarupppasamy SubburajSingapore University of Technology and Design


Session Chairs:Xingyu JiangSouthern University of Science and TechnologyBastien VenzacUniversity of Twente

1600 - 1630KEYNOTE Microfluidics for Synthesis and Screening of Nanoscale Drug CarriersXingyu JiangSouthern University of Science and Technology

1630 - 1645Ex-Vivo Culture of Testis and Epididymis Tissues in a Microfluidic DeviceBastien VenzacUniversity of Twente

1645 - 1700Vascular Endothelial Responses to Fluid Flow under Hypoxic ConditionNaoyuki TakahashiTohoku University

1700 - 1715Detachable Acoustophoretic System for Fluorescence-Activated Sorting at Single Droplet LevelPeixian LiSingapore University of Technology and Design

1715 - 1730Microengineered Artery-on-a-Chip for Study of Diabetic VasculopathyChengxun SuNanyang Technological University of Singapore

Special Symposium 11: Surgical Robotics

Session Chair:Hongliang Ren National University of Singapore

1600 - 1615 Robotic Intervention Utilizing Bioengineering Based Therapeutic MethodsIchiro Sakuma University of Tokyo

1615 - 1630Augmented Reality for Orthopeadic SurgeryJaesung Hong Daegu Gyeongbuk Institute of Science and Technology

1630 - 1645 Medical Robot Link Architecture Connected to Smart Cyber Operating Theater (SCOT) Ken Masamune Tokyo Women’s Medical University

1645 - 1700 Transluminal Robotics with Delicate Continuum and Context Awareness Hongliang Ren National University of Singapore

1700 - 1715 Robot-Assisted Interventions under Intra-Operative MRI-Based Guidance Ka-Wai Kwok University of Hong Kong

1715 - 1730 Biomimetic Wrinkled MXene Pressure Sensors towards Collision-Aware Robots Catherine Cai National University of Singapore

Special Symposium 12:Organ-on-Chip

Session Chairs:Ben Maoz Tel Aviv University Danny Ben-Zvi Institute of Medical Research Israel- Canada The Hebrew University-Hadassah Medical School, Jerusalem

1600 - 1615 Development of 3D Cell Constructs with Perfusable Vascular Networks Generated from iPSC-Derived Endothelial Cells Yu-Suke Torisawa Kyoto University

1615 - 1630 Patient-Specific Stem Cell-Based Blood Brain Barrier-on-Chip Platform Enables Predictive Personalized Medicine Applications Gad Vatine Ben Gurion University of The Negev

1630 - 1645 Organs-on-a-Chip: A New Tool for the Study of Human Physiology Ben M. Maoz Tel Aviv University

1645 - 1700 Drug Delivery Devices and Organ Chip Devices for Ophthalmologic Applications Hirokazu Kaji Tohoku University

1700 - 1715Intestine-Chip: A Human iPSC-Derived Microfluidic Chip Model for Studying Inflammatory Bowel Disease Michael J. Workman Cedars-Sinai Medical Center

1715 - 1730 Bariatric Surgeries as a Discovery Platform for Metabolic Diseases and Basic Biology Danny Ben-Zvi The Hebrew University of Jerusalem

1730 - 2030 Gala DinnerFaber Peak Singapore

End of Day 3



TIME THURSDAY, 12 DECEMBER, Day 4

VENUE LECTURE THEATRE 7A ENGINEERING AUDITORIUM EA-02-11 EA-06-03 EA-06-04 EA-06-050800 - 0930 Registration0930 - 1015 Plenary Lecture 5

AI and Data-Driven Support for Prevention, Intervention, and Cure in HealthcareBeng Chin OoiNational University of Singapore Session Chair: Martin BuistLecture Theatre 7A

1015 - 1045 Co£ee Break1045 - 1215 Session 4.1


Session Chairs:Yusuke TsubokoWaseda UniversityKazuma NakamuraWaseda Univercity

1045 - 1100Development of a Mechanical Simulator of the Systemic and Coronary Circulation for Hemodynamic Evaluation of Transcatheter Aortic Valve ReplacementYusuke TsubokoWaseda University

1100 - 1115Fabrication of Dissecting Aortic Aneurysm Model and Visualization of Flow in False Lumen Before and After Placing the Stent GraftKazuma NakamuraWaseda Univercity

1115 - 1130Experimental Investigation of the Influence of Stent Design on Jailed Struts and Stent Malapposition Using a Left Main Coronary Artery ModelKaito MatsubaraWaseda University

1130 - 1145Application of Class-E Amplifier to Transcutaneous Energy Transmission System for a Totally Implantable Artificial Heart -Comparison of Resonance Circuit and Rectifier Mode-Masatoshi SondaTokyo University of Science

1145 - 1200Blood Flow Interactions in Aorta - Pulmonary Artery SystemTakahisa YamamotoNational Institute of Technology, Gifu College

1200 - 1215A Minimally-Occlusive Cu© Method Utilizing Ultrasound Vascular Imaging for Stress-Free Blood Pressure Measurement: An Implementation of Machine Learning to Improve the Measurement Precision.Kazunori UemuraNational Cerebral and Cardiovascular Center

Session 4.2Bioelectronics & Electroceuticals

Session Chairs:Chih-Wei PengTaipei Medical UniversityPingqiang CaiNanyang Technological University of Singapore

1045 - 1100Development of a Novel Implantable Bladder Pressure SensorChih-Wei PengTaipei Medical University

1100 - 1115Correlating Electromechanical Patterns with Hand Gestures Based on Cytoadhesion-Inspired Hybrid ElectrodesPingqiang CaiNanyang Technological University of Singapore

1115 - 1130Highly Stretchable and Tissue-Adhesive Near-Field-Communication (NFC) Patch DevicesKento YamagishiSingapore University of Technology and Design

1130 - 1145An Update Algorithm for On-Line Monitoring Cardiac Output System Based on Pulse Wave ContourQiwen YuZhejiang University

1145 - 1200Relationship Between Lipid Accumulation and Electrical Characteristics of 3T3-L1 Cells under Three-Dimensional Culture ConditionDaiki ZemmyoKeio University

1200 - 1215Spatially Selective Pelvic Nerve Neuromodulation for Functional Mapping of Visceral NervesMarlena RaczkowskaNational University of Singapore

Session 4.3Neuroengineering/ Neurotechnology

Session Chairs:Xue FengTsinghua UniversityChuanchu WangInstitute for Infocomm Research

1045 - 1100KEYNOTE Climbing-Inspired Twining Electrodes and Buckled-Based3D Bioelectrodes for Peripheral NeuromodulationXue FengTsinghua University

1100 - 1115NeuroWiz – a Software System to Acquire, Preprocess and Visualize Wide-Band Neural DataChuanchu WangInstitute for Infocomm Research

1115 - 1130An Electroencephalography-Based Brain-Computer Interface System with Immersive Virtual Reality Using Android Mobile Device for A©ective Computing StudiesZheng Yang ChinInstitute for Infocomm Research, Agency for Science Tecnhology and Research

1130 - 1145LANDSCAPE: An MRI-Based Project for Computational NeuromodulationHanna LuThe Chinese University of Hong Kong

1145 - 1200Short-Term Neuromuscular Electrical Stimulation Increased Corticomuscular Coherence of the HealthyRui XuTianjin University

Session 4.4Big Data, Healthcare Analytics & AI

Session Chairs:Junhua ZhangYunnan UniversityMing Lun OngNational University of Singapore

1045 - 1100Skeletal Bone Age Assessment in Radiographs Based on Convolutional Neural NetworksJunhua ZhangYunnan University

1100 - 1115Actionable Machine Learning Using Electronic Health RecordsMing Lun OngNational University of Singapore

1115 - 1130Machine Learning Improves Early Prediction of Low Birth Weight and Reveals Unexpected PredictorShier Nee SawAgency for Science Technology and Research (A*STAR)

1130 - 1145Deep Learning Based Prediction of Colorectal Cancer Recurrence and SurvivalDanliang HoNational University of Singapore

1145 - 1200Unsupervised Deep Learning for Automated Fundus Image Quality Assessment in Retinopathy of PrematurityPavitra KrishnaswamyInstitute for Infocomm Research

1200 - 1215Choroid Segmentation in Optical Coherence Tomography Images Using Deep LearningRuchir SrivastavaInstitute for Infocomm Research

1215 - 1230Evaluation of Federated Deep Learning Approaches on Multi-Centre Clinical ImagesIvan Ho MienInstitute for Infocomm Research

Session 4.5Musculoskeletal Biomechanics

Session Chairs:Kamran HassaniScience and Research Branch,Islamic Azad UniversityRui MoShanghai Jiao Tong University, China

1045 - 1100Fluid-Structure Interaction Analysis of the Optic Nerve Head in GlaucomaKamran HassaniScience and Research Branch,Islamic Azad University

1100 - 1115Study on the Estimation of Whole Weight-Bearing Based on Local Force MeasurementRui MoShanghai Jiao Tong University, China

1115 - 1130A Trial of Quantification of Mastication by AccelerationKonishi YutoButsuryo of College Osala

1130 - 1145TSC1mKO Kyphosis Mice Model – Can Muscle Loss Induce Intervertebral Disc Degeneration?Wing Moon Raymond LamNational Univeristy of Singapore

1145 - 1200Mechanical Characterizations of Metallic Sca©olds Fabricated by Selective Laser Melting Processes for Bone Tissue EngineeringXue WangNational University of Singapore

1200 - 1215Analysis of Fatigue Behavior in Forearm Muscle Based on Evaluation of Muscular Endurance Characteristics Using Force MyographyTatsuya IgarashiHirosaki University

Special Symposium 13:Liquid Biopsy for Disease Diagnosis

Session Chairs:Ali Asgar Saleem Bhagat National University of SingaporeHan Wei Hou Nanyang Technological University of Singapore

1045 - 1100Cancer-Specific Metabolic Profiles of Circulating Tumor Cells on Live Single-Cell Mass SpectrometryKazufumi HondaNational Cancer Center Research Institute

1100 - 1115Evaluation of Combinatorial Therapies Using a Preclinical Microfluidic ModelBee Luan KhooCity University of Hong Kong

1115 - 1130Centrifugal Microfluidic Technology for Circulating Tumor CellsMinseok S. KimDaegu Gyeongbuk Institute of Science and Technology

1130 - 1145Single Cell-Based Diagnosis of Liquid Biopsies with Extremely Low Cellularity Using DEPArray TechnologyTong Seng LimMenarini Biomarkers Singapore

1215 - 1300 Closing Ceremony & Award PresentationLecture Theatre 7A

1300 - 1400 Farewell Lunch

End of Conference



NOTES NOTES

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