the cart fund coins for alzheimer’s research trust a project of rotary clubs of southeast us
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The CART Fund Coins for Alzheimer’s Research Trust A project of Rotary Clubs of Southeast US. Rotary International District 7570. My Classmate Governor Byron (07-08) and lovely wife Kathy. Introduced by Assistant Governor Mary Miller. In Governor Byron’s - PowerPoint PPT PresentationTRANSCRIPT
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The CART FundCoins for Alzheimer’s Research Trust
A project of Rotary Clubs of Southeast US
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Rotary International District 7570
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My Classmate Governor Byron (07-08) and lovely wife Kathy
Introduced by Assistant Governor Mary Miller
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In Governor Byron’sDecember 2007 Newsletter, this photo and caption
appeared together.
Youth Exchange from page 1
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What we will cover today•What is Alzheimer’s
disease?•How does Alzheimer’s
affect the brain?•What is CART?•CART History
•Example CART Research Grants
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Alzheimer’s DiseaseWhat you need to know
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Alzheimer’s (AHLZ-high-merz) disease is brain failure
-a progressive brain disorder that gradually destroys
brain cells and affects a person's memory, ability to learn, make judgments,
communicate, and carry out basic daily activities.
Alzheimer’s is not normal aging. It is a progressive, fatal disease,
the cause is unknown and it has no cure.
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New meanings for familiar Words* Sun-downing
* Wandering
*Elopement
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Alzheimer’s Disease: From Basic Research to Disease Cure
The CART Fund Columbia, SC
May 7, 2008
Sanjay W. PimplikarCleveland Clinic
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We do not know for sure!
Amyloid hypothesis
What causes AD?
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Alzheimer’s destroys brain cells
There are 100 billion nerve cells, or neurons, creating a branching network.
Signals traveling through the neuron forest form memories, thoughts and feelings.
Alzheimer’s destroys neurons, thus also destroying memories, thoughts, impulse control, personality, etc
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Aβ
AICD
AD
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Alzheimer’s causes the brain to shrink
(due to the death of neurons)
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History of CART.
In October 1995, the Sumter, S.C., Rotary Club initiated the effort to prove
CART works by conducting an eight month testing program which was highly
successfulJuly 1996: District 7770 in South Carolina adopted CART as a project.
April 1999: Our first grant of $100,000 is made to Emory University's Alzheimer's Research
Center under the leadership of Dr. Allan Levey. AFAR (American Federation for Aging Research).
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History of CART(cont)
.
In the 18 months from January 1999 until June 2000, 10 more Rotary districts of the Carolinas and Georgia adopt CART as a project. The first
Board of Directors meeting was held in November 2000, bylaws were adopted. They state that
100% of donated funds must go to Research!!
Each district that joins the CART program has two representatives on the board and two votes.
The District Chair and the DGN
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11District Team Training Seminar
Zones 33 & 34
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Success to date: $3.5m
11District Team Training Seminar
Zones 33 & 34
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11District Team Training Seminar
Zones 33 & 34
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This is how we are related
11District Team Training Seminar
Zones 33 & 34
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1999 Emory University: Allan I. Levey, M.D. Ph.D. and Jim Lau
2001 Case Western Reserve University: Karl Herrup, Ph.D. and Gary Landreth
2003 University of Pennsylvania: John Q. Trojanowski, M.D. Ph.D.
History of CART Awards
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2006 University of Texas Medical Branch: Claudio Soto, Ph.D.
2007 Mayo Clinic Jacksonville: Todd E. Golde, M.D., Ph.D.
2008 The Cleveland Clinic: Sanjay W. Pimplikar, Ph.D.
2009: Mayo Clinic, Jacksonville, Fl: Dr. Malcom LeissringS, Ph.D.
History of CART Awards
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2010 University of Kentucky: Paul Murphy, M.D.$250,000
2010 University of Wisconsin-Madison: Dr. Luigi Puglieli, Ph. D.
$150,0002010 University of Pennsylvania:
Dr. Kurt Brunden, Ph.D.$50,000
History of CART Awards
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2011 University of Pennsylvania:Dr. Kurt Brunden
$250,000 2011 Case Western:
Dr. Gary Landreth$100,000
2011 Mass GeneralDr. Brad Hyman $50,000
History of CART Awards
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2012 Dr. Maya Koronyo-HamaouiCedars Sinai, Oakland, CA.
$250,000
2012 University of WashingtonDr. Valarie Daggett, Ph. D.
$100,000
History of CART Awards
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How devastating is AD on a personal level. We lose
contact with the individual that we knew.•How do we know what
they are thinking and feeling?
•How do they see themselves?
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1967
1996
1996
19971997
1998
1999
2000
William Utermohlen: Self portraits
“..depict sadness, anxiety, resignation, feeling of feebleness and shame.”(NY Times, Oct 24, 2006)
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You can help!! Lets find the cause, and find the
cure/prevention for this dreaded disease!!