the cell cycle year 12 biology c9. draw a circle to the left hand side of the page
DESCRIPTION
Divide the circle into four sectionsTRANSCRIPT
![Page 1: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/1.jpg)
The Cell Cycle
Year 12 Biology C9
![Page 2: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/2.jpg)
Draw a circle to the left hand side of the page
![Page 3: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/3.jpg)
Divide the circle into four sections
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Divide the right-hand quarter into fourths.
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Label the quarters
G1 Phase
S Phase
G2 Phase
M
Phase
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Label the phases of M-phase (Mitosis)
G1 Phase
S Phase
G2 Phase
M
Phase
Prophase
Metaphase
AnaphaseTelophase
![Page 7: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/7.jpg)
Add details of each phase of mitosis.
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
![Page 8: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/8.jpg)
Add details of each phase of mitosis.
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
![Page 9: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/9.jpg)
Add details of each phase of mitosis.
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
![Page 10: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/10.jpg)
Add details of each phase of mitosis.
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
![Page 11: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/11.jpg)
![Page 12: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/12.jpg)
Add details of each phase of the cell cycle
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
![Page 13: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/13.jpg)
Add details of each phase of the cell cycle
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
![Page 14: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/14.jpg)
Add details of each phase of the cell cycle
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
![Page 15: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/15.jpg)
Add details of each phase of the cell cycle
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
![Page 16: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/16.jpg)
Add checkpoints
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
Check for DNA Damage
Cell big enough?
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Add checkpoints
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
Check for DNA SynthesisCell size
Check for DNA Damage
Cell big enough?
![Page 18: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/18.jpg)
Add checkpoints
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
Check for DNA SynthesisCell size
Check for DNA Damage
Cell big enough?
![Page 19: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/19.jpg)
Add checkpoints
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
Check for DNA SynthesisCell size
Hold to break down cyclins
Check for DNA Damage
Cell big enough?
![Page 20: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/20.jpg)
Add checkpoints
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
Check for DNA SynthesisCell size
Pause to break down cyclins
Check for DNA Damage
Cell big enough?
![Page 21: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/21.jpg)
Add checkpoints
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
Check for DNA SynthesisCell size
Pause to break down cyclins
Check for DNA Damage
Cell big enough?
![Page 22: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/22.jpg)
Add external growth factors…
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
Mitosis promoting factor (e.g. hormone)
Nucleus
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Nucleus makes internal regulators..
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
Mitosis promoting factor (e.g. hormone)
Nucleus
Kinase Cyclin
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Nucleus makes internal regulators..
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
Mitosis promoting factor (e.g. hormone)
Nucleus
CDK complex
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CDKs build up…
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
CDK complex
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CDKs build up…
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
CDK complex
![Page 27: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/27.jpg)
CDKs build up…
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
CDK complex
![Page 28: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/28.jpg)
CDKs build up…
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
CDK complex
![Page 29: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/29.jpg)
CDKs build up…
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
CDK complex
![Page 30: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/30.jpg)
CDKs start to break down…
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
CDK complex
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CDKs start to break down…
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
CDK complex
![Page 32: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/32.jpg)
Only when all CDK has broken down can the cell proceed to Metaphase…
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
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G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
Only when all CDK has broken down can the cell proceed to Metaphase…
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G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
G0 phase
At telophase the cell can go into G0 phase (and remain there) or continue on to the cell cycle…
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G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
G0 phase
Differentiation
The cell may then become differentiated into any one of the 200 body cells in humans..
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Role of inhibitors…•p27blocks the build up of CDK complex during G1 and prevents movement to S phase
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
CDK complexp27
![Page 37: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page](https://reader035.vdocument.in/reader035/viewer/2022062401/5a4d1b327f8b9ab05999b957/html5/thumbnails/37.jpg)
Role of inhibitors…•p27blocks the build up of CDK complex during G1 and prevents movement to S phase•p53 stops cell cycle at any point if DNA is damaged.
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
CDK complexp53
p53
p53
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Role of inhibitors…If mutations occur to inhibitors – cancer may result i.e. uncontrolled cell cycle.
G1 Phase
S Phase
G2 Phase
Prophase
Metaphase
AnaphaseTelophase
Cell growth
Energy
Organelles
DNA Synthesis
Cell Growth
Energy
CDK complex