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Cells"Long ago it became evident that the key to every biological problem must finally be sought in the cell; for every living organism is, or at some time, has been a cell."E.B. Wilson
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The Cell Theory
The cell theory united plant and animal sciences by recognizing that the cell is the fundamental component of all living organisms, from orchids and earthworms to human beings.
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But what is a cell?
An enclosurel Boundary
l Interior regionlHereditary
store
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Contributors to the Cell Theory:
§ Robert Hooke (named cells)
§ Anton Van Leeuwenhoek (saw microorganisms)
§ Robert Brown (discovered the nucleus)
§ Matthias Schleiden (plants are made of cells)
§ Theodor Schwann (animals are made of cells)
§ Rudolf Virchow (cells come from cells)
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Robert Hooke 1635~1703
In 1665The first person to
see and name cells.
He examined (dead) cork bark with a primitive microscope
Saw little cubicles which he called cells (cell = room, cubicle).
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Anton van Leeuwenhoek(1632~1723)
Investigated the natural world using experimental methods supported by the evidence of the senses.
He made with his own hand certain most excellent lenses…
He invented the microscope……
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And saw wondrouscreatures
Spirogyra…described by Leeuwenhoek
"Passing just lately over this lake, . . . and examining this water next day, I found floating therein divers earthy particles, and some green streaks, spirally wound serpent-wise, and orderly arranged, after the manner of the copper or tin worms, which distillers use to cool their liquors as they distil over. The whole circumference of each of these streaks was about the thickness of a hair of one's head. . . all consisted of very small green globules joined together: and there were very many small green globules as well."
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Robert Brown
Robert Brown reported the existence of nucleus in 1831.
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Matthias Jacob Schleiden(solicitor & botanist 1804 ~ 1881).
Founder of the cell theory.Plants were aggregates of "fully
individualized, independent, separate being, namely the cells themselves."
Author of Basic Scientific Botany, the definitive textbook on botany at the middle of the 19th century.
Promoted commercial production of microscopes
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Theodor Schwann(1810 - 1882).
Noticed nucleated units in animal tissue.
After discussions with Schleiden concluded that animals were composed of cells.
Did experiments that challenged Spontaneous Generation.
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Rudolf Virchowpathologist (1858)
Omnis cellula e cellula" (where a cell arises, there a cell
must previously have existed).
First to state the cell theory:
"Every animal appears as a sum of vital units, each of which bears in itself the complete characteristics of life."
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The Cell Theory
w All living things are composed of cells and cell products.
w The cell is the smallest unit of life.w Living creatures come from the
growth and division of single cells.
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Cells Come in Different Shapes
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Nostoc and Amoeba and Neurons
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Diatom & Mouse Hair
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Cells Come in Different Sizes
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Ostrich eggs are the biggest cells.
Most cells can only be seen with a microscope.
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Microscopes:
Types of MicroscopesLight Microscope
Phase~Contrast MicroscopeScanning Electron
MicroscopeTransmission Electron
Microscope
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Basic Cell Types
ProkaryoticSimple StructureSmallCell MembraneCytoplasmRibosomesNO ORGANELLES
Naked DNA
Eukaryotic Complex StructureSmall to LargeCell MembraneCytoplasm Ribosomes on membranesMembrane-Bound OrganellesNucleus contains DNA
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Prokaryotic Cells
Simple Structure: Membrane, Cytoplasm, Ribosomes, and Naked DNA
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Prokaryotic Cells
Archeabacteria EubacteriaCyanobacteria
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More Eubacteria
Lactobacillus Nitrosomas E. coli
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A Basic Eukaryotic Cell
Note the complex
inner structure
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Eukaryotic Cell
AmoebaAmorphous shape & pseudopods
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Sperm and Eggs
Small Motile Cells
Large Sessile Cells
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Red Blood Cells
Small cells without a nucleus. Filled with hemoglobin for oxygen transport throughout the body
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Plant and Animal Cells
Cell Membrane Cell Membrane &Cell Wall
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Cell Membrane
The fluid mosaic model: Phospholipids with embedded proteins.
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Cytoplasm
Cell substanceFilled with solids,liquids,
organelles, cytoskeletal support fibers & inner network of membranes.
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Nucleus
The Nucleus: Control Center of the Cell2003/2004Cells: The Basic Units of Life32
Mitochondria
Cell Powerhouse: Site of Cellular RespirationC6H12O6 + O2 ? CO2 + H2O
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Endoplasmic Reticulum
Rough & Smooth Endoplasmic Reticulum
Protein Synthesis Lipid Synthesis
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Golgi Apparatus
A system of sacs and vesicles in the cytoplasm
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Chloroplasts
Chloroplasts : Site of PhotosynthesisCO2 + H2O ? C6H12O6 + O2
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Central Vacuole
Characteristic of a Plant Cell
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Cytoskeleton
Rat Smooth Muscle Cells: Actin & Myosin
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Flagella & Cilia
Trypanosome
Trypanosome Euglena Tracheal Cells
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Sources
¢ http://www.ucmp.berkeley.edu/history/leeuwenhoek.html
¢ http://www.clovis.cc.nm.us/ms/adkinsj/biol113/Lectures/history_of_biology.htm
¢ http://buglady.clc.uc.edu/biology/bio104/hist_sci.htm
¢ http://www.avonmaitland.on.ca/GDCI/mains/stu-proj/science/1996/3a/cells/enrich/ryan/index.htm
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§ http://members.aol.com/Poobah78/biology.html
§ http://www.nih.gov/nigms/news/science_ed/whatcell.html
§ http://biology.lsa.umich.edu/~www/bio100/lec4/index.htm§ http://www.umanitoba.ca/faculties/medicine/units/history/lesion/lesion10
.html
§ http://www.nceas.ucsb.edu/~alroy/lefa/Virchow.html
§ http://ostracon.biologie.uni-kl.de/b_online/e01/schleide.htm§ http://wwwihm.nlm.nih.gov/
§ http://www.biology.arizona.edu/cell_bio/tutorials/pev/main.html