the cestodes (tape worm)
DESCRIPTION
The Cestodes (tape worm). Nematode trematode. common features of Class Cestoda. 1. Adult worm is flattened ribbon-like 2. Body wall: Tegument and subtegument; and no body cavity. body wall construction :. substantia corticalis : - PowerPoint PPT PresentationTRANSCRIPT
![Page 1: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/1.jpg)
The Cestodes (tape worm)
![Page 2: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/2.jpg)
Nematode trematode
![Page 3: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/3.jpg)
![Page 4: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/4.jpg)
common features of Class Cestoda
1. Adult worm is flattened ribbon-like
2. Body wall: Tegument and
subtegument;
and no body cavity.
![Page 5: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/5.jpg)
body wall construction:substantia corticalis:microvilli 、 cytomere 、 basal membrane①scratch intestinal mucosa②conduce(to)attachment③expand surface area of absorption ④possess sensory function⑤to resist digestion
subcutaneous stratum:annuliform muscle、 vertical muscle、oblique musclehelp the proglottid Slipping and falling off
![Page 6: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/6.jpg)
3.The body is composed of a head, neck an
d segmented strobilus ( 链体 ). The head ha
s suckers, rostellum ( 顶突 ) and hooklets o
r sucking grooves. The neck is the budding
zone from which segments are formed. The
strobilus consists of immature, mature and
pregnant proglottides.
![Page 7: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/7.jpg)
Strobila (链体 ):( 1 ) Scolex (头节 ) - equipped with organs of attachment: suckers, hooks, grooves.( 2 ) Neck (颈部) - germinal portion (3) Proglottids (节片 ) - immature, mature, gravid( 孕节 ).
![Page 8: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/8.jpg)
4. They are hermaphroditic. There is a set of female and male reproductive organs in every mature proglottid.
![Page 9: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/9.jpg)
5. Digestive tract is absent. Nutrition is absorbed by villi of body surface.
Nematode trematode
![Page 10: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/10.jpg)
6. They are biohelminths. Intermediate hosts are indispensable.7. All adult worms parasitize digestive tracts of mammals.
![Page 11: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/11.jpg)
8. The developing stages in intermediate hosts are called metacestode ( 中绦期 ), such as cysticercus ( 囊尾蚴 ), hydatid cyst ( 棘球蚴 ), cysticercoid ( 似囊尾蚴 ), procercoid ( 原尾蚴) , plerocercoid (裂头蚴) .
![Page 12: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/12.jpg)
PHYSIOLOGY AND PATHOGENESIS: 1. Surface absorption capabilities. 2. Highly developed reproductive functions. 3. Anaerobic metabolism (无氧代谢 ).
![Page 13: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/13.jpg)
PHYSIOLOGY AND PATHOGENESIS: (2) 4. No external environment development. 5. All species are parasitic. 6. Pathogenic stage may be adult or the larvae.
![Page 14: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/14.jpg)
Tapeworms are classified into two orders: (1).Cyclophyllidea ( 圆叶目 ): The head is spherical with suckers, hooklets. The uterus has no opening. One intermediate host is required. The eggs contain an oncosphere ( 六钩蚴 ). They are medically important, such as Taenia solium ( 链状带绦虫 ), Taenia saginata ( 肥胖带绦虫 ) and Echinococcus granulosus ( 细粒棘球绦虫 ).
![Page 15: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/15.jpg)
Cyclophyllidea (圆叶目 )
![Page 16: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/16.jpg)
(2). Pseudophyllidea (假叶目 ): The head is spear-like with sucking grooves. The uterus has an opening. Two or more intermediate hosts are required. The eggs contain a coracidium (钩球蚴) and have to get into water to develop. Human being occasionally get infection. This worms include Spirometra mansoni (曼氏迭宫绦虫) and Diphyllobothrium latum (阔节裂头绦虫) .
![Page 17: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/17.jpg)
Pseudophyllidea (假叶目 ):
![Page 18: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/18.jpg)
Cyclophyllidea (圆叶目 )
Pseudophyllidea (假叶目 ):
![Page 19: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/19.jpg)
Taenia solium(pork tapeworm)
Adult worms live in human small intestin
e causing taeniasis (绦虫病 ). The larval stag
e (Cysticercus cellulose 猪囊尾蚴 ) lives in p
ig or human tissues causing human cysticer
cosis(囊尾蚴病或囊虫病) .
![Page 20: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/20.jpg)
GENERAL INTRODUCTION:1. Worldwide distribution.2. Large tapeworm.
3. Taenia solium: Laval infection cause serious clinical disease --- CYSTICERCOSIS.
![Page 21: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/21.jpg)
Adult:
Taenia solium (pork tapeworm)
![Page 22: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/22.jpg)
Adult of the Pork Tapeworm
averages 2 – 4 meters long.
![Page 23: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/23.jpg)
I. Morphology
1. Adult is flattened ribbon-like, creamy white in color, measures abo
ut 2-4 m and has 700-1000 proglottides.
scolex : global, 1mm. With 4suckers, 1rostellum (顶突) and
25-50 hooklets arranged in a double crown
It consists of neck: it’s the narrowest part of the body and budding zone
containing germinative tissue
immature proglottides:width>length
strobila mature proglottides: width=length
gravid proglottides: width<length
![Page 24: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/24.jpg)
Immature proglottides are transverse rectangle, located in th
e anterior part of the body and inner organs are developing.
Mature proglottides are square in shape and located in the m
id part of the body and have 150-200 testes, a centrally straight
uterus and 3 lobes of ovary .
Pregnant(gravid) proglottides are longitudinal rectangle, locat
ed in the posterior part of the body and contain a branched uter
us filled with eggs. The number of main branches on each side
of the uterus stem is 7-13.
![Page 25: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/25.jpg)
![Page 26: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/26.jpg)
scolex
![Page 27: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/27.jpg)
Mature proglottid
![Page 28: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/28.jpg)
India Ink Technique
• Note : less than 13 lateral uterine branches (one sid
e). In this species the uterus of the gravid proglottid has between 7 and 13 lateral branches on each side.
![Page 29: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/29.jpg)
2. Egg, The eggs of Taenia saginata and T. solium are indistinguishable morphologically. The eggs are spherical, diameter 31 to 43 µm, with a thick radially striated brown embryophore ( 胚膜 ). Inside each is an oncosphere ( 六钩蚴 ) with 6 hooklets.
t
![Page 30: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/30.jpg)
3.Cysticercus cellulose. It is a semitransp
arent and elliptic bladder, like a white p
omegranate seed ( 石榴籽 )about 0.6-1
cm. There is fluid and a white scolex wit
h 4 suckers and hooklets in the bladder.
![Page 31: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/31.jpg)
Under stimulation of bile
The scolex invaginates
in the bladder The scolex evaginates
![Page 32: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/32.jpg)
![Page 33: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/33.jpg)
Cysticerci in myocardium
![Page 34: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/34.jpg)
II. Life cycle 1. final host: man,
2. Intermediate host: swine (or man),
3. Infective stage: cysticercus and egg,
4. Infective mode: eating raw bean-pork or egg
5. Site of inhabitation: adult in small intestine; cysticercus in tissues,
6. Infective mode of cysticercosis: endogenous, exogenous auto-infection and foreign source;
7. Life span: more than 25 years; cysticercus can survives 5-6 years in human body.
![Page 35: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/35.jpg)
![Page 36: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/36.jpg)
Life Cycle of Taenia solium
Attach to intestinal mucosascolex evaginates adults grivad proglottides develop into fall off duodenum In human small intestine and are 2-3 months discharged in feces man eats cysticercus in raw pork
───────────────────────────── swine ingests eggs In intermediate hosts man gets infection
60-70days
develop into cysticercus onchosphere hatch
in all parts of the body larval migration in duodenum penetrate intestinal wall into blood stream
![Page 37: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/37.jpg)
III. Pathogenesis and Clinical Manifestations
1. Taeniasis: It is caused by the adult resi
ding in small intestine of the man. The adult
irritates the small intestine causing discomf
orts, such as abdominal pain, anorexia, chr
onic indigestion, diarrhea, emaciation and e
tc. The patient is usually no obvious sympt
om, only complaining passing proglottides.
![Page 38: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/38.jpg)
2. Cysticercosis: It is caused b
y the cysticerci living in human t
issues. The manifestations vary
with the number of cysticerci an
d the tissues and organs involve
d. Cysticercosis is divided into f
our types.
![Page 39: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/39.jpg)
The subcutaneous nodules are usually found in head, limbs, neck, abdomen and back. They are movable and painless.
(1) Subcutaneous type:
![Page 40: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/40.jpg)
(2) muscles type:
![Page 41: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/41.jpg)
Note this cysticercus in the tongue
![Page 42: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/42.jpg)
The cysticercus is usually found in the vitreous body or subretina. Visual disturbance often occurs. The died body of worm may provokes local inflammation causing blindness.
(3) Ocular type:
![Page 43: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/43.jpg)
(4) Brain type: The symptoms are related to the site of infection. The patients may manifest headache, nausea, vomiting, epilepsy ( 癫痫 ), paralysis ( 瘫痪 ), weakness in limbs, diplopia (复视) , dizziness, mental disorder. Epilepsy is the most frequent symptoms of brain cysticercosis.
![Page 44: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/44.jpg)
Brain type
![Page 45: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/45.jpg)
IV. Diagnosis 1.Taeniasis: Confirmative diagnosis of ta
eniasis is made by finding gravid proglotti
des or egg in stool. (1) direct fecal smear
(2) brine floatation technique **(3) cello
phane-tape technique
![Page 46: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/46.jpg)
the examination of a transparent plastic adhesive tape previously applied to the perianal region
![Page 47: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/47.jpg)
Showing some eggs of Taenia spp. and
an egg of E.vermicularis.
Scotch-tape smear
![Page 48: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/48.jpg)
2. For cysticercosis (1) Specific diagnosis is difficult to establish, the history and adult worm infection attribute to strong suspicion. (2) Biopsy to subcutaneous lesions. (3) computerized axial tomography
![Page 49: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/49.jpg)
(CT) or (MRI). are used for the diagnosis of brain type and ophthalmoscope examination is used for ocular form.
3. Immunological tests are for reference only. IHA, ELISA, Dot-ELISA McAb-CAg.
![Page 50: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/50.jpg)
V. Treatment and prevention
1. Treatment of Taeniasis: (1) Chinese herb med
icine: pumpkin seed and areca nut ( 槟榔 ) . The r
ecognition of a scolex in the patient’s stool after t
he application of taenifuge is important. When th
e entire worm has been expelled, the therapy is s
uccessful, otherwise the strobila regrow. (2) Prazi
quantel may be used.
![Page 51: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/51.jpg)
2. Treatment of cysticercosis: Surgical removal is required for ocular and superficial cysticercoses. Praziquantel may be used to treat brain cysticercosis , but the patients should take praziquantel in hospital.
![Page 52: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/52.jpg)
3. Prevention: (1) Health education (2) Avoid eating raw bean-pork. (3)avoid pigs eating human stool. (4) sanitary inspection of slaughter and sanitary disposal of night soil.
![Page 53: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/53.jpg)
VI. Epidemiology
This disease is prevalent all over the world except Muslim and Jew areas. The infection of T. solium is closely associated with the method of pig-raising and the sanitary condition.
![Page 54: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/54.jpg)
Taenia saginata(肥胖带绦虫,牛带绦虫,牛肉绦虫或无钩绦虫 )
Adult worms live in human small intesti
ne causing taeniasis. Larval stage (Cysti
cercus bovis) lives in cattle tissues. This
disease is prevalent all over the world.
![Page 55: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/55.jpg)
1. Body length
T. solium T. saginata
Differences between T. solium and T. saginata
![Page 56: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/56.jpg)
2. scolex
T. solium T. saganita
![Page 57: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/57.jpg)
Mature proglottids of Taenia sp.
![Page 58: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/58.jpg)
3. Mature proglottid
T. solium T. saginata
![Page 59: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/59.jpg)
4. Gravid proglottid
.
T. solium•In this species the uterus of the gravid proglottid has between 7 and 13 lateral branches on each side.
T. saginatathe uterus of the gravid proglottid has between 15 and 30 lateral branches on each side
![Page 60: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/60.jpg)
5. cysticercus
Cysticercus cellulose Cysticercus bovis
![Page 61: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/61.jpg)
COMPARASON OF THE TWO TAPEWORMS:
T. solium T. saginata
1. Size 2-4m 4-8m
2. Scolex Rostellum
& hooks No
3. Mature Proglottid:
Ovary 3 lobes 2 lobes
4. Gravid proglottid :
Lateral Uterine Branches<13 >15
![Page 62: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/62.jpg)
COMPARASON OF THE TWO TAPEWORMS: (2)
T. solium T. saginata 5. Intermediate Host: Swine & Humans, Cattle 6. Disease caused : Taeniasis & cysticercosis, Taeniasis only 7. Infective stage: Egg & Cysticercus, Cysticercus Only8. Mode of infection : Cross or autoinfection, Cross only
![Page 63: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/63.jpg)
COMPARASON OF THE TWO TAPEWORMS: (3)
T. solium T. saginata
9. Diagnosis :
Gravid proglottid, Gravid proglottid
Egg may be found in stool, Egg may be found in stool,
Perianal egg exam Perianal egg exam
![Page 64: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/64.jpg)
T. solium T. saginata
10. Clinical significance:
Much more important, Less important
11. Chemotherapy:
Should be instant , Not so urgent
COMPARASON OF THE TWO TAPEWORMS: (3)
![Page 65: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/65.jpg)
II. Life cycle The intermediate host is cattle and cysticercus
bovis can not live in human. The others same as those of T. solium.
III. Pathogenesis:
Usually only single worm is present and the patient is no symptom. Some patients may complain of migrating proglottids from anus with pruritus at the perianal region. Abdominal discomfort, nausea, vomiting, constipation or diarrhea may occur.
![Page 66: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/66.jpg)
IV. Diagnosis Finding of gravid proglottids or eggs at the perianal region b
y cellophane tape method.
V. Epidemiology:
T. saginata has a world-wide distribution. Human infection is acquired from consumption of raw beef containing the cysticercus bovis. Cattle become infected from grazing on the ground polluted by human feces containing the eggs of the parasite. It is important to have latrines and manure pits far away from the pastures.
VI. Treatment:
Same as tha of T. solium
![Page 67: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/67.jpg)
** Echinococcus granulosus(dog tapeworm)
There are three developmental stage in lyfe cycl
e including egg, larva and adults. Adult worms
live in the small intestine of dogs, wolves and
other canines. The larval stage lives in the tiss
ues of herbivores or men, so man is a intermed
iate host of Echinococcus granulosus. It cause
s echinococcosis (hydatid disease or hydatido
sis). Hyditid cyst chiefly lives in the liver of hu
man body.
![Page 68: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/68.jpg)
The globular scolex bears a rostellum with 24-40 hooklets and 4 sukers.
Slender neck. Immature proglottid Mature proglottid Gravid proglottid consists
of uterus with irregular lateral branches filled with eggs.
All kinds of proglottids only one.
Adult morphology
![Page 69: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/69.jpg)
Egg The egg,34 to 41um in diameter, has a brown,thick,radially striated embryophore surrouding an oncosphere,six-hooked embryo, and is similar in appearance to those of Taenia worms
![Page 70: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/70.jpg)
Hydatid fluid
Hydatid cyst
Protoscolex
Brood capsules
Daughter cysts
Granddaughter cysts
Laminated layer
Germinal layer
contents
Cyst wall
hydatid sand
Hydatid Cyst:
![Page 71: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/71.jpg)
Hydatid cyst Largest larval stage of all tap
eworms
![Page 72: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/72.jpg)
Protoscolex
Notice the scolex armed with suckers and hooklets.
![Page 73: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/73.jpg)
Life cycle
The definitive hosts are dogs, wolves, and other canines. The adult inhabits their small intestine. The eggs discharged from the ruptured proglottid, pass to outside with feces. The intermediate hosts are sheep, cattle, goats, camels, horses and human beings.
![Page 74: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/74.jpg)
Life cycle
![Page 75: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/75.jpg)
When the intermediate hosts ingests eggs, they hatch in the duodenum and penetrate the intestinal mucosa and are carried by the blood to the liver, brain, heart, bones, kidneys and other tissues. When they are earten by a definitive host such as dogs, each of the individual protoscolex may develop into an adult worm in about 7 to 8 weeks. Then the adult worm may discharge eggs.
![Page 76: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/76.jpg)
Conclusion of life cycle
1.Definitive host: dogs, wolves, and other canines.
2.Intermediate host: herbivores and humans.3.Infective stage: protoscloex (to definitive host)
egg (to intermediate host)
4.Route of transmission: protoscolex are eaten by definitive host, eggs are ingested by intermediate host.
![Page 77: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/77.jpg)
Pathogenesis and syptomatology
The common pathogeneses are:a) Local compression and excitation:
the cyst acts as a sapce-occupying lesion,produces damage on adjacent tissues, example for liver,lung,brain,kidney and so on
![Page 78: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/78.jpg)
Hydatid cyst in liver
Cyst in liver, there may be hepatomegaly, right upper quadrant pain, jaundice, hepatic mass, etc.
![Page 79: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/79.jpg)
Hydatid cyst in lungsCyst in lungs may
give rise to cough,shortness of breath, hemoptysis( 咯血 ), or chest pain.
![Page 80: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/80.jpg)
Hydatid cyst in brainCysts within the central nervous system will produce serious damage. The common symptoms are headache, nausea, vomiting,epilepsy, dizziness,mental confusion,and weakness in limbs.
![Page 81: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/81.jpg)
Hydatid cyst in kidneyCysts live in th
e kidney may induce circulating antigen-antibody complexes deposit in the kidney,initiating inflammation
![Page 82: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/82.jpg)
Pathogenesis and syptomatology
b) Secondary hydatid cyst inflammation:
Rupture of hydatid cyst may release the fluid, lead to dissemination of infection and produce secondary hydatid cysts, or provoke inflamation.
![Page 83: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/83.jpg)
![Page 84: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/84.jpg)
Pathogenesis and syptomatology
C) Allergic reaction: the cyst fluid contains parasite antigens, which can sensitize the host, so pruritus and urticaria occur usually. If the cyst ruptures spontaneously or during trauma or surgical removal,life-threatening anaphylaxis can occur.
![Page 85: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/85.jpg)
Pathogenesis and syptomatology
d) Poisoning and gastrointestinal dysfunction
The patient may present with anorexia, loss of body weight, maldevelopment due to the toxin of parasite.
![Page 86: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/86.jpg)
Laboratory diagnosis
observe the protoscolex with microscope in sputum, 尿液、腹水或胸水
IHA 、 ELISA Dot-ELISAChest X-ray, CT, MRI and ultrasonography( 超声 )
![Page 87: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/87.jpg)
The end
See you next time
![Page 88: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/88.jpg)
plerocercoid 裂头蚴(spirometra mansoni)
cysticercus 囊尾蚴
hydatid cyst 棘球蚴
procercoid 原尾蚴(Diphyllobothrium latum)
cysticercoid 似囊尾蚴(hymenolepis nana)
![Page 89: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/89.jpg)
head has suckers, rostellum and hooklets
neck budding zone from which segments are formed
strobilus
immature proglottides
mature proglottides
pregnant proglottides
![Page 90: The Cestodes (tape worm)](https://reader033.vdocument.in/reader033/viewer/2022061508/56814bf4550346895db8e767/html5/thumbnails/90.jpg)
Laminated layer
Germinal layer
Protoscolex
Brood capsules
Daughter cysts
Granddaughter cysts