the covid-19 and cardiovascular nexus · 2020-04-13 · covid-19 and cardiovascular disease •...

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The COVID-19 and Cardiovascular Nexus Anthony DeMaria MD Judy and Jack White Chair in Cardiology University of California, San Diego

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Page 1: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness

The COVID-19 and Cardiovascular Nexus

Anthony DeMaria MDJudy and Jack White Chair in Cardiology

University of California, San Diego

Page 2: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 3: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 4: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness

COVID-19 and Cardiovascular Disease

• Patients with CV disease are very susceptible

• CV Disease pts have more severe illness and outcome

• Infection can activate quiescent CV disease

• Evidence for myocardial injury (Myocarditis)

• Effect of CV drugs on course of disease

• Therapeutics and CV disease

Page 5: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 6: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness

Cardiovascular Disease Predisposes to COVID-19

Page 7: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 8: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 9: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness

Cardiovascular Disease Confers a Worse Outcome with COVID-19

Page 10: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness

Characteristics of Patients with COVID-19

Page 11: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness

Myocardial Injury with COVID-19

Page 12: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 13: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 14: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 15: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 16: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 17: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 18: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 19: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 20: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 21: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 22: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 23: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness

Therapeutics and COVID-19

Page 24: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 25: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 26: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 27: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 28: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 29: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 30: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness
Page 31: The COVID-19 and Cardiovascular Nexus · 2020-04-13 · COVID-19 and Cardiovascular Disease • Patients with CV disease are very susceptible • CV Disease pts have more severe illness

COVID-19 and Cardiovascular Disease

• Patients with CV disease are very susceptible

• CV Disease pts have more severe illness and outcome

• Infection can activate quiescent CV disease

• Evidence for myocardial injury (Myocarditis)

• Effect of CV drugs on course of disease

• Therapeutics and CV disease