the egg. egg microvilli zona pellucida zp zona pellucida glycoproteins
Post on 20-Dec-2015
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TRANSCRIPT
The Egg
Egg Microvilli
Zona Pellucida
Zp
Zona Pellucida Glycoproteins
The Sperm
Axonemes and Sliding Microtubules
Sperm Surface Asymmetry
Sea Urchins
Sea Urchin Acrosome Reaction
Sea Urchin Fertilization
Direct Bindingof Sperm to Egg
Competition Assay to Identify Egg Receptor
Isolated Zona Pellucida Blocks Sperm Binding
+ ZP+ ZP(2 cell)
Isolated ZP3 Blocks Sperm Binding
Man
Man Man
NAcGlc
O-linked Oligosaccharide
NAcGlc
Man
Man Man
NAcGlc
O-linked Oligosaccharide
NAcGlc
Gal Gal
+ 2UDP-Gal
Galactosyl Transferase
GalactosylTransferase
Role of Galactosyl Transferase in Binding to Egg
Acrosome Reaction & Penetration of Zona Pellucida
Vesiculation of Acrosome
Fertilins and ADAMs family proteins
Fertilin- hydrophobic domain
Model for Fertilin Function During Fertilization
Incorporation of Sperm Into Egg – Role of Microvilli
Incorporation of Sperm Components Into Egg
Formation of Sperm Pronucleus
Persistence of Sperm Mitochondria In Embryos
Propagation of Calcium “Wave”