THE FIRST ANNUAL

JUDSON J. VAN WYK

PRIZE

MELVIN M. GRUMBACH UCSF

MEL GRUMBACH the (academic) early years

Born 21 December, 1925. Yes, he’s 80 years old! 1948 MD Columbia University 49-51 Pediatric Intern/Resident, Columbia U. 51-53 Captain USAF, Oak Ridge TN 1952 Met Jud Van Wyk while interviewing for his fellowship at Johns Hopkins 53-55 Fellowship under Lawson Wilkins, along with Jud Van Wyk

Van Wyk Wilkins Grumbach Shephard Migeon

“Mel and I were littermates together!’ JJ Van Wyk

BIBLIOGRAPHY

1. Wilkins L, Bongiovanni AM, Clayton GW, Grumbach MM, and Van Wyk JJ(1954): The present status of the treatment of virilizing adrenal hyperplasia withcortisone: Experience of 32 years. Modern Problems in Pediatrics, Vol l.Supplements ad Anna les Paediatrici, S Karger, Basel, pp. 329-345.

2. Wilkins L, Bongiovanni AM, Clayton GW, Grumbach MM, and Van Wyk JJ(1954): Virilizing adrenal hyperp lasia: Its treatment with cortisone and the natureof the steroid abnormalities. The Human Adrenal Cortex Part II. Ciba FoundationColloquia on Endocrinology, Vol VIII, pp. 460-481.

3. Wilkins L, Grumbach MM, and Van Wyk JJ (1954): Chromosomal sex in"ovarian agenesis". J Clin Endocrinol Metab 14:1270-1271.

4. Bongiovanni AM, Eberlein WR, Grumbach MM, Van Wyk JJ, and Clayton GW(1954): Conjugates of adrenal corticoids in human plasma. Proc Soc Exper BiolMed 87:282-287.

5. Grumbach MM, Bongiovanni AM, Eberlein WR, Van Wyk JJ, and Wilkins L(1955): Cushing' s syndrome with bilateral adrenal hyperplasia: A study of theplasma 17 hydroxycor ticosteroids and the response to ACTH. Bull Johns Hopk insHospital 96:116-125.

7. Grumbach MM, Van Wyk JJ, and Wilkins L (1955): Chromosomal sex in gonadaldysgenesis (ovarian agenesis): Relationship to male pseudo-hermaphroditism andto human sex differentiation. J Clin Endocrinol Metab 15:1161-1193.

8. Wilkins L, Grumbach MM, Van Wyk JJ, Shepard T, and Papadatos C (1955):Hermaphroditism: Classification, diagnosis, selection of sex, and treatment.Pediatrics 16:287-301.

9. Childs B, Grumbach MM, and Van Wyk JJ (1956): Virilizing adrenalhyperplasia: A genetic and hormonal study. J Clin Invest 35:213-222.

MEL GRUMBACH the (academic) later years

55-65 Instructor, Asst. Prof., Assoc. Prof. Columbia U. First Chief of Pediatric Endocrinology First 10 fellows: Ducharme, Kaplan, Morishima, Abrams, Conte, Burr, Youlton, Grant, Sizonenko, and August 66- Professor of Pediatrics, UCSF 66-86 Chairman of Pediatrics, UCSF 1973 President, Assoc Med Schl Ped Dept Chairs 1975 President, LWPES 1978 President, Western Soc. Peds. Res. 1981 President, Endocrine Society 1989 President, American Pediatric Society 1994 Professor Emeritus

MEL GRUMBACH’S PEDIATRIC ENDOCRINOLOGY FELLOWS

1956-1993

42 Professors 23 Associate/Assistant Professors 3 Administration or Industry 12 Private, Group or HMO Practice 1 Deceased 81 40 Chiefs of Divisions of Pediatric Endocrinology 13 Department Chairs 2 Deans

MEL GRUMBACH’S HONORS a very abbreviated list

1971 Borden Award; Am Acad Pediatrics 1980 Robert H. Williams Leadership Award; Endocrine Soc. 1983 Institute of Medicine 1985 Clinical Endocrinology Trust Medal; British Endo. Soc. 1985 Fellow, Am Assn for the Advancement of Science 1991 DM, Honoris Causa, U of Geneva 1992 Fred Conrad Koch Award (with SL Kaplan) Endo. Soc. 1995 American Academy of Arts and Sciences 1995 National Academy of Sciences 1997 John Howland Award; American Pediatric Society 2000 D, Honoris Causa, U. Rene Descartes, Paris V 2006 Judson J. Van Wyk Award, LWPES

MEL GRUMBACH’S BOSS

THE GRUMBACH FAMILY

MEL and JUD, 1993