the gain-of-function deliberative process (carrie wolinetz)

8/19/2019 The Gain-of-Function Deliberative Process (Carrie Wolinetz)

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Zdk Mfob-la-AubctolbJkionkrftovk Xrlckss

Cfrrok J. ]liobktz, XdJ Fsslcoftk Jorkctlr alr Scokbck Xliocy

Laaock la Scokbck Xliocy, BOD


2/12

>

Xrleltobm Milnfi Dkfitd Skcuroty

tdrlumd Ioak Scokbcks ^kskfrcd

F rlnust ioak scokbcks rkskfrcd kbjkfvlr os crotocfi tl prleltobm

punioc dkfitd fbj wkii-nkobm ob iomdt la kvlivobm tdrkfts plskj nyeocrlnofi pftdlmkbs.

• [SM supplrts f jovkrsk ioak scokbcks rkskfrcd plrtali ol

• ^kskfrcd obvlivobm pltkbtofiiy jfbmkrlus pftdlmkbs dfvk

obdkrkbt nolsfakty fbj nolskcuroty ros`s

• Sfakiy rkfiozobm tdk nkbkaots la sucd rkskfrcd rkquorks kaakctovk

pliocoks, prfctocks, fbj lvkrsomdt


3/12

Sfakty stfbj-jlwb fbj Bftolbfi NolsfaktyStkwfrjsdop Elbtd

Akjkrfi Kxpkrts Skcuroty Fjvoslry Xfbki

(AKSFX) ^kplrt

Afst-Zrfc` Fctolb Cleeottkk lb Skikct Fmkbt^kmuiftolbs (AZFC-SF^) ̂ kplrt

Mfob-la-Aubctolb Jkionkrftovk Xrlckss

3

Strkbmtdkbobm Nolsfakty fbj Nolskcuroty

ob Ioak Scokbcks ^kskfrcd

^kckbt ifn obcojkbts dfvk spurrkj f skroks la pliocy fctovotoksny tdk [SM foekj ft rkobalrcobm cleeotekbts tl nolsfakty,

nolskcuroty, fbj rksplbsonik clbjuct la rkskfrcd felbm fii

stf`kdlijkrs.


4/12

SpkbjobmLutsojk BOD

Spkbjobm

ft BOD

Fs pfrt la f rkbkwkj kepdfsos lb nolsfakty fbj nolskcuroty, tdk ros`s

fbj nkbkaots fsslcoftkj wotd mfob-la-aubctolb (MLA) rkskfrcd frk

nkobm cfrkaui iy rk-kxfeobkj.

• MLA stujoks frk lbk fpprlfcd tl fjjrkssobm aubjfekbtfi scokbtoa oc

qukstolbs.

• MLA stujoks dfvk tdk pltkbtofi tl7

Dkip jkaobk tdk aubjfekbtfi bfturk la dlst-pftdlmkb obtkrfctolbs

Kbfnik fsskssekbt la tdk pfbjkeoc pltkbtofi la kekrmobm

obakctolus fmkbts

Obalre punioc dkfitd fbj prkpfrkjbkss kaalrts

Aurtdkr ekjocfi clubtkrekfsurk jkvkilpekbt

Mfob-la-Aubctolb ^kskfrcd

:


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Ckrtfob MLA stujoks dfvk rfoskj nolsfakty fbj nolskcuroty

clbckrbs.

• Cluij kbmobkkrkj pftdlmkbs plsk f pfbjkeoc tdrkft oa

tdky wkrk tl nk fccojkbtfiiy lr obtkbtolbfiiy rkikfskj arle

f ifnlrftlry<

• Cluij tdk obalreftolb mkbkrftkj arle ckrtfob MLA stujoksnk eosuskj tl tdrkftkb punioc dkfitd lr bftolbfi skcuro ty<

Xliocy qukstolbs7

– [bjkr wdft clbjotolbs cfb tdksk stujoks nk sfakiy

clbjuctkj<

– Sdluij tdos typk la rkskfrcd nk clbjuctkj ft fii<

;

Clbckrbs fnlut Ckrtfob MLA

Stujoks


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1

MLA Jkionkrftovk Xrlckss fbj

^kskfrcd Aubjobm Xfusk

Jkionkrftovk Xrlckss

Zdk [SM fbblubckj f prlckss tl rk-kvfiuftk tdk

pltkbtofi ros`s fbj nkbkaots fsslcoftkj wotd MLA

rkskfrcd obvlivobm pftdlmkbs wotd pfbjkeoc pltkbtofi.

^kskfrcd Aubjobm Xfusk

Jkionkrftovk prlckss os fcclepfbokj ny f pfusk ob

aubjobm alr prlgkcts tdft efy nk rkfslbfniy

fbtocopftkj tl mkbkrftk obaiukbzf, EK^S, lr SF^Svorusks wotd kbdfbckj pftdlmkbocoty fbj/lr

trfbseossonoioty ob efeefis vof tdk rksporftlry rlutk.


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^os` & Nkbkaot

Fsskssekbts (^NF)Mrypdlb Scokbtoaoc clbjuctros` & nkbkaot fsskssekbts

la MLA stujoks

Bftolbfi Fcfjkeoks

Clbvkbk punioc alrues tlmkbkrftk nrlfj joscussolb

fbj rkckovk punioc fbj ltdkrstf`kdlijkr obput

BSFNNSkrvks fs tdk laaocofi

fjvoslry nljy alr prlvojobmfjvock lb lvkrsomdt la tdosfrkf la jufi usk rkskfrcd

[SM MLA

Xliocy

Jkvkilpekbt

Xrlckss

MLA Jkionkrftovk Xrlckss

=


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Zfs`

>

Xrlvojk alrefi rkcleekbjftolbs

tl tdk [SM lb tdk clbckptufi

fpprlfcd tl tdk kvfiuftolb la

prlplskj MLA stujoks

Jkiovkrfnik >

^kcleekbjftolbs tl tdk [SM

obalrekj ny tdk rksuits la tdk

ros` fbj nkbkaot fsskssekbts

fbj ltdkr

obput

Zfs`

>

Xrlvojk alrefi rkcleekbjftolbs

tl tdk [SM lb tdk clbckptufi

fpprlfcd tl tdk kvfiuftolb la

prlplskj MLA stujoks

Jkiovkrfnik >

^kcleekbjftolbs tl tdk [SM

obalrekj ny tdk rksuits la tdk

ros` fbj nkbkaot fsskssekbts

fbj ltdkr

obput

Zfs`

6

Fjvosk lb tdk jksomb,

jkvkilpekbt, fbj clbjuct la ros`‘

nkbkaot fsskssekbt la MLA stujoks

Jkiovkrfnik 6

Arfekwlr` alr tdk jksomb fbj

clbjuct la ros` fbj nkbkaot

fsskssekbts

la

MLA

stujoks

Zfs`

6

Fjvosk lb tdk jksomb,

jkvkilpekbt, fbj clbjuct la ros`‘

nkbkaot fsskssekbt la MLA stujoks

Jkiovkrfnik 6

Arfekwlr` alr tdk jksomb fbj

clbjuct la ros` fbj nkbkaot

fsskssekbts

la

MLA

stujoks

Zdk Cdfrmk tl tdk BSFNN

4


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Zoekiobk la Efglr Kvkbts ob tdk MLA

Jkionkrftovk Xrlckss

?


10/12

BSFNN tl aobfiozk ots aobjobms fbj

rkcleekbjftolbs tl tdk [SM nfskj lbstf`kdlijkr akkjnfc` fbj fjjotolbfi obputs fbj

fbfiysos

[SM tl clbsojkr BSFNN rkcleekbjftolbs lb fclbckptufi fpprlfcd tl tdk kvfiuftolb la

prlplskj MLA stujoks tlwfrjs tdk jkvkilpekbt

la bkw pliocy

68

Bkxt Stkps


11/12

Stf`kdlijkr obput os crotocfi tl fb kaakctovk pliocy

jkvkilpekbt prlckss.

BSFNN jrfat rkcleekbjftolbs fbj ekktobm vojkl frcdovks

fvfoifnik7 dttp7//lsp.lj.bod.mlv/laaock-noltkcdblilmy-

fctovotoks/nolskcuroty/bsfnn

Auturk lpplrtubotoks alr stf`kdlijkr pfrtocopftolb7

• BSFNN ekktobm (Sprobm >861)

• Kefoi fbytoek tl7

Stf`kdlijkr Obput

bsfnnHlj.bod.mlv

66


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• BOD Laaock la Scokbck Xliocy

– ]knsotk7 dttp7//lsp.lj.bod.mlv/

– Nilm7 dttp7//lsp.lj.bod.mlv/ubjkr-tdk-pliosclpk

– Zwottkr7 dttps7//twottkr.cle/cwliobktzbod

– Sunscronk tl tdk LSX iostskrv

• Skbj fb kefoi tl IOSZSK^QHiost.bod.mlv

wotd ’Sunscronk LSX\Bkws― ob tdk ekssfmk

• Scokbck, Sfakty, Skcuroty (S3) – dttp7//www.pdk.mlv/s3/Xfmks/jkafuit.fspx

Fjjotolbfi ^kslurcks

6>

the gain-of-function deliberative process (carrie wolinetz)

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