the internet and youth mental health
TRANSCRIPT
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The Internet and Youth Mental
Health
Helen ChristensenEHUB Members: Kathy Griffiths, Kylie Brittliffe, Anthony Bennett,
Jola Samoc, Alison Neil, Lou Farrer, Nicole Burgess, AmeliaGulliver, Dan Costin others
Westmead Hospital
30th of October 2007
Depression is prevalent in young people, withestimates that about 5% of 13-17 year olds willexperience depression in one year.
Depression is recognized as an important issue byyoung people themselves. 57% report they know ayoung person who had attempted or completedsuicide (Youth Poll 2005).
The issues identified as of greatest importance byyoung people were drug and alcohol use,depression and suicide (ahead of not securing a jobor sexuality) National Youth Survey (2004)
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There are effective treatments for depression
These include a range of talking therapies
including cognitive behaviour therapy.
Yet very few seek or obtain help. Less than 40% of
those with depression get help from a health
professional.
Young people do not seek help from GPs preferring to
get support from their friends, family, followed by
the internet, magazines, and school counselors.
Many cannot label depression (Burns and Rapee,
2006), and do not know what treatments might be
effective.
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Million dollar question
How can we delivery effective treatments to so manyyoung people given
They don’t seek help
They don’t seek help from health professionals
They don’t go to GPs
They don’t know what they have or what they need todo
And we don’t have the workforce even if help weresought ?
Solution
Design an internet application which offers
cognitive behaviour therapy (an effective
treatment), evaluate whether it works, see if it
is cost effective, and offer it free on the world
wide web.
This endeavour will be the main basis of my
talk but first!
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Why the internet? The Internet
provides a means of accessing
young peopleEstimated 817 million users worldwide Feb 2005
http://www.internetworldstats.com/top20.htm with13,410, 816 Australians (65.4%). 6th highest internetpenetration
75% internet users have sought health information onthe net (Pew Internet Poll)
Young people are the heaviest users of the Internet
The internet provides a platform to deliver interactivesoftware and has enormous reach
The internet is engaging.
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What do we know about the way
young people interact on the internet?
Majority have access: 2% have wireless
Both parents and children say they are less carefulthan should be on the internet (62%)
67% see it as a positive medium in lives
26-75% seek health information
20% seek help for difficult health issues- depression,druguse and sex health
Most aim to communicate with friends and participatein online communities.
There is rapid growth in the use of the
Internet using interventions
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Web therapy papers as a function of year.
Society for Internet interventions ISRII
2004-2007
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A range of international internet
interventions for young people
Websites to reduce suicide ideation (Pim Cuipers and Ad Kerkhof)(Netherlands)
Websites for encopresis (Lee Ritterband) (USA)*
Websites with e-support for adolescents with mentally ill family member(Louisa Drost) Netherlands
Websites for alcohol use for young people (Riper, Netherlands)*
Websites offering support after brain Injury: USA: Net Family ProblemSolving (FPS) to reduce parental distress after brain injury* (but includedvideoconferencing).
Websites to promote health and wellbeing in space crews (James Carter)(USA)
Websites for eating disorders (Barr Taylor-Standford, USA)
* Denotes a least one RCT to evaluate effectiveness
What is happening in Australia for
young people?
INTERNET INTERVENTONS
MoodGYM and the Youth Mood Project* (ACT)
Internet BRAVE Net CP for childhood anxiety (Spence et al., 2006)*(NSW)
Marie Teeson/ Gavin Andrews Climate for Schools: Alcohol* (NSW)
Sophie Reid and mobile phones for depression (VIC)
Ron Rapee and others at Macquarie University for anxietyhttp://www.psy.mq.edu.au/brave/ (NSW)
Dan Costin and e-health cards for help seeking (ACT)*
Susan Paxton: Eating disorders (VIC)*
Reachout! GAME- interactive game currently being evaluated bySwinbourne University (NSW-VIC)
Anxiety and Panic in Young People Kenardy (QLD)
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What is happening in Australia for
young people?EDUCATION INTERVENTIONS
BluePages in combination with MoodGYM (Tromso, Norway)*
YOUTH HEALTH SITES
Kids Help Line
Ybblue
Reachout!
QUALITY INDICATORS
Tim Edwards- Hart: Site evaluation tool
BULLETIN BOARDS AND ONLINE GROUPS
BlueBoard?
OTHER INTERNET INTERVENTIONS: Young People?
Francis Kay Lambkin, Amanda Baker and co-morbidity interventions
Sue Lauder Moodswings (Young People)
Judy Proodfoot Bipolar Disorder: Volunteers
Watch this space: Headspace?
Useful list of references: Azy Barak
http://construct.haifa.ac.il/~azy/refchild.htm
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Today’s talk: a case study of
MoodGYM
• Describe the MoodGYM program
• Examine whether it is effective
• Whether it works in the real world?
• Cost effective
• Do people use it?
• Can we tell if people change who use it?
• In what sort of settings can it be used effectively foryoung people?
• Is there a case for standards and dissemination?
www.moodgym.anu.edu.au
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Log on and introduction
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The Modules
Feelings Module
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Thoughts module
Goldberg Anxiety and Depression Scale 2
Warpy Thoughts Questionnaire 1
Identifying dysfunctional thoughts
Methods to contest such thoughts
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Unwarping Module
Goldberg Anxiety and Depression Scale 3
Other methods for overcoming warpy thoughts
Individualized on the basis of The Warpy
Thoughts Questionnaire: Need for approval,
need for love, need for success, etc
eg. Being a reporter, assertiveness, self-
esteem training
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De stressing module
Goldberg Anxiety and Depression Scale 4
Life Event Stress (Tennant and Andrews)
Relaxation (relaxation, meditation, music)
Pleasant Events Schedule (Lewinsohn)
Parental style and stress (MOPS, Parker)
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Relationships Module
Goldberg Anxiety and Depression Scale 5
Warpy Thoughts Questionnaire 2
Simple problem solving
Typical responses to relationship break-up
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Workbook
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Added features
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What does the back end look like?
How do we collect the data?
MoodGYM
Fire
wall
database
CMHRAdmininterface
Moodgymapplication onserver with adatabase serverand firewall.
Administrator updates webpages,downloads user data and sets up newtrials
internet
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MoodGYM
Fire
wallUsers Com’ity trial
database
Users Com’ity trial
Users Com’ity trial
Communitytrials
CMHRAdmininterfaceUsers find the
web site and logon and join trial
Does it work?
Efficacy, as established in RCTs
Effectiveness, through evaluations of community
users
Cost-effectiveness
Scalability to a mass audience
Popularity
And as short as it need be
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Efficacy
Christensen, Griffiths and Jorm BMJ, 2004; Mackinnon etal., in press. 12 month data shown above.
10
12
14
16
18
20
22
24
0 1 2 3 4 5
Time
CE
S-D
De
pre
ss
ion
1 MoodGYM
2 BluePages
3 Health Coach
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It is effective
No significant difference between RCT trial
participants and ‘free range users’.
Christensen et al. A comparison of changes in anxiety anddepression symptoms of spontaneous users and trialparticipants of a CBT website. JMIR, 2004, 6(4): e46.
Change over five modules
Module
54321
De
pre
ssio
n
7
6
5
4
3
2
Status
Public
yes
Public n=115 Trial n=41
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Cost-effectiveness analysisSpecify comparators:
- individual, face-to-face CBT with a psychiatrist
(P-CBT)
- GP visits with drug therapy (GP-DRUG)
Prof Jim Butler
Need estimates of:
- cost of MoodGYM and comparators
- effectiveness of MoodGYM and comparators
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Cost of comparators
the unit cost of therapy is assumed to be constant and
independent of the number of patients treated
M-CBT
GP-DRUG
P-CBT
n
AC
n1 n2
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Results – break-even throughput
n1 = 359
n2 = 753
Throughput of completers has exceeded these
levels
MoodGYM is less costly than P-CBT and GP-
DRUG
Site is cost-effective
The efficacy of M-CBT, as demonstrated in an RCT of
the program, is comparable with that of P-CBT and
GP-DRUG.
Throughput levels for MoodGYM result in a unit cost
of therapy which is lower than for P-CBT and GP-
DRUG
Therefore, in cost-effectiveness terms, M-CBT is
dominant – it is less costly and at least equally
effective as the two comparator therapies.
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Scalability
Stats downloaded 20-08-07 for 2007. Monthly visits=34,000
Usage by country
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Dose response effects and how
much is enough
Analysis was undertaken using SAS Proc
Mixed (9.1) which can handle planned
missingness (due to the non-administration of
particular modules in some conditions).
LS Means
4
5
6
7
0 1 2 3 4 5 6
Module
De
pre
ss
ion
Module 1
Modules 1, 4 and 5
Modules 1 and 5
Modules 1, 2 and 5
Modules 1, 2, 3 and 5
All Modules
Depression
Least Squares means for Goldberg Depression Scale as a function of Modulecompleted. Treatment by Time is statistically significant
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Effective?
• Depression and dysfunctional thinking improve
• A single module of brief CBT is not effective relative
to other versions in reducing depression symptoms.
• Extended CBT with or without behaviour strategies
results in greatest reduction of depression
symptoms
• The stress reduction modules do not add
Drop out on open access is high
Eysenbach,G. 2005 The Law of Attrition, JMIR, 7 (1):e5,
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Theoretical models
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Patient related factors
Education, age, location
Patient expectations of treatment
Condition related factors
Symptom severity
Dysfunctional thinking levels
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Therapy related factors
Length of treatment
Experience of the intervention and
improvement
Health systems effects
Provision of support through care
management: tracking by telephone or email
Endorsement of the program by a health
professional
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Environments likely to facilitate
adherence
General practice environments (Christensen,
Griffiths, Hickie and Moore, 2007: Pilot study in GP
practices).
Community call centre environments environments
(Farrer, Christensen, Griffiths, Mackinnon and
O’Neil)
School environments (Neil, Christensen, Griffiths,
Mackinnon and O’Kearney).
Alison Neil, Helen Christensen, Kathleen Griffiths,
Andrew Mackinnon and Richard O’Kearney.
The YouthMood Project:
An Evaluation of MoodGYM with an Adolescent
Population
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Australian School ProgramsProgram Program type No. published
trials
Data on efficacy /
effectiveness available
Adolescent Coping with Depression (Australian Version)
Treatment 1 No evidence
Adolescents Coping with Emotions (ACE)
Indicated 3 Promising
Aussie Optimism Universal 3 Promising
Best of Coping Universal 4 Insufficient data
Beyondblue Schools Project Universal 0 Insufficient data
Cool Kids Program Indicated 1 Promising
FRIENDS Universal 7 Strong
MindMatters Universal 0 Insufficient data
MoodGYM Universal 2 Promising
NSW School-Link Program Universal 0 Insufficient data
Penn Prevention Program (Australia) Universal 1 No evidence
Problem Solving for Life Universal 2 Promising
Resourceful Adolescent Program (RAP) Universal 4 Strong
Neil, A. L. & Christensen, H. (2007). Australian school-based prevention and early intervention
programs for anxiety and depression: A systematic review. Medical Journal of Australia, 186, 305-
308.
Aims
To establish whether MoodGYM is effective in reducingstudents’ vulnerability to depression and anxiety.
To test MoodGYM with a larger and more diversesample, following promising results from the pilotstudies.
To use a universal intervention with the help ofclassroom teachers
O’Kearney, R., Gibson, M., Christensen, H., & Griffiths, K. M. (2006). Effectsof a cognitive-behavioural internet program on depression, vulnerability todepression and stigma in adolescent males: a school-based controlled trial.Cognitive Behaviour Therapy, 35, 43-54.
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Participants
30 schools participated
56% of participants were female
17% lived on a farm or rural property
Mean age = 14.33 years
30% previously depressed
34% received help from a doctor or counsellor
Measures
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Intervention-
The MoodGYM Program
http://moodgym.anu.edu.au
Online CBT program
Five Modules: Feelings, Thoughts, Unwarping,
Destressing and Relationships
Interactive quizzes and exercises
ProcedureConsent obtained
(n = 1450)
All schools complete
pre-intervention questionnaire
(n = 1346)
Group A
Completes MoodGYM
(n = 529)
Group B
Completes usual classes
Group B
Completes post-intervention questionnaire
(n = 805)
Group A
Completes post-intervention questionnaire
(n = 445)
Group A
Completes 6-month follow-up questionnaire
(n = 426)
Group B
Completes 6-month follow-up questionnaire
(n = 735)
Group B
Completes MoodGYM
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Data Analysis
Mixed models repeated measures ANOVA
Repeated measures
Students clustered within classes
ICC ~ 0.03
Class effects minimal
ITT analysis
Mixed Model ANOVA-
Depression
0
4
8
12
16
Pre Post FU
Time
CE
S-D
Control
MoodGYM
F (2, 1215.57) = 1.61, p = 0.20
Follow-up ES = ~ 0.20
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Mixed Model ANOVA- Anxiety
0
2
4
6
8
10
12
Pre Post FU
Time
RC
MA
S
Control
MoodGYM
F (2, 1224.82) = 12.26, p < 0.001
Follow-up ES = ~ 0.30
Mixed Model ANOVA- ‘Clinical’ Sub-
group
0
2
4
6
8
10
12
14
16
18
Pre Post FU
Time
RC
MA
S
Control
MoodGYM
F (2, 292.97) = 2.30, p = 0.10
Follow-up ES = ~ 0.30
0
5
10
15
20
25
30
Pre Post FU
Time
CE
S-D
Control
MoodGYM
F (2, 290.60) = 1.37, p = 0.25
Follow-up ES = ~ 0.30
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Conclusions
Effective classroom resource
Suitable for a variety of classroomenvironments
Developing classroom support materials
Evaluation of classroom materials
Models for dissemination: Simplified
criteria for effectiveness (Flay et al.
2004)
Provision of manuals and technical support YES
Evidence of delivery in the real world to target YES
Levels of exposure, engagement, adherence YES
Two RCTs in identified settings YES
Replication with different samples YES
Cost effectiveness YES
Dose analysis YES
Demonstration of public health impact NO
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Simplified criteria for
dissemination
Provision of provider support and fidelity YES
Evidence of scalability YES
Clear cost information available NO
Monitoring and evaluation tools YES
Factors to assure sustainability Possibly?
Conclusions
The internet has a place in offering both self-help andmaterials to be used in clinical settings
The internet may have a role in potentiating initial helpseeking-or in recovery. This is an area that mightbe developed for early psychosis?
There is evidence that self-help interventions areeffective for anxiety and depression.
This area is rapidly growing but research at theadolescent level is difficult.
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Htttp://ecouch.anu.edu.au
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Terms of use and privacy
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Assessment instrumentsGoldberg Anxiety and Depression Scales
Prime MD PHQ Panic Items (2)
Social anxiety item FQ (1)
Small animal phobia (1)
Stages of change
Perceived stigma
Help from people –
Knowledge of treatments: Medical psych lifestyle
Marital status, separation, loss
Substance use
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Mental Health literacy
Symptoms
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Users
Assessment
Tailored Targeted
GADstream
PanicStream
SocialAnxiety
Depression
Divorce and separationBereavement
Tailoring: symptom
information is used to
determine the delivery
of “specialized”
information on web
pages
Targetting: group
membership is used to
determine the delivery
of “targetted”
information on web
pages
Depression Stream
Assessment of MHL
Mental Healthliteracy
Stigma intervention
Toolbox
Assessment of stigma and pre-intervention symptoms
Risk factors
Predictive tests
Treatments thatwork
Assessment of MHL
CBT
IPT
Relaxation
ActivityAssessment of symptoms
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E-couch
Fire
wallUsers Com’ity trial
database
Users Com’ity trial
Users Com’ity trial
Users GP
Users Schools
Full functionality with trials running simultaneously and administratorsprovided with access to research data
Users MCI Canada
CMHRAdmininterface
Trialmanager
Sydney
Trialmanager
Canberra
Trialmanager
Canada
Where to from here- research
questions?
Research and development of:
The integration of applications into mainstreamservices as adjuncts
The use a ‘new class of health worker’ to implementevidence based applications
The creation of new services through the developmentof virtual clinics with a consumer focus
The evaluation of short interventions for mental healthoutcomes
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Moodgym and BluePages
Contributors
Anthony Bennett, David
Berriman, Kelly Blewitt, Kylie
Brittliffe, Kimberley Evans,
Cathy Frazer, Chloe Groves,
David Hawking, Anthony
Jorm, Claire Kelly, Betty
Kitchener, Ailsa Korten, Nick
Newman,Liz Parkes, Ruth
Parslow, Richard Pass,
Sarah Vancea, Janine
Walker, Tim Windsor