the other cell division: making sex cells. meiosis – a source of distinction ever wonder why you...
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Meiosis – A Source of Distinction
Ever wonder why you don’t look exactly like either your mother or father? Or why you and your siblings are not identical?
It’s all in MEIOSIS!
2 Major Roles of Meiosis
1. Make GAMETES (egg and sperm); diploid (2n) cells make haploid (n) cells
2. Genetic Variation
GAMETESMeiosis takes a cell with two copies
of every chromosome (diploid) and makes cells with a single copy of every chromosome (haploid).
This change (diploid haploid) is critical if two gametes combine to make a new individual
In meiosis, one diploid cells produces four haploid cells.
Meiosis scrambles the specific forms of each gene that each sex cell (egg or sperm) receives. Increases genetic diversity (accomplished through independent assortment and crossing-over).Genetic diversity is important for the evolution of populations and species.
Genetic Variation
Meiosis
Parent cell – chromosome pair
Chromosomes copied
1st division - pairs split
2nd division – produces 4 gamete cells with ½ the original no. of chromosomes
Homologous ChromosomesHomologous Chromosomes are:
1. The same size
2. The same shape
3. Have the same genes
4. Different forms of gene
Meiosis I : Separates Homologous Chromosomes●Interphase
●Each of the chromosomes replicate
●The result is two genetically identical sister chromatids which remain attached at their centromeres
Prophase I●Each pair of sister chromatids
move to their homologous pair and join together (synapsis) in a group of four called a tetrad.
●This is when crossing over can occur.
●Crossing Over is the exchange of segments during synapsis.
Metaphase I
●The chromosomes line up at the equator (metaphase 1 plate) attached by their centromeres to spindle fibers from centrioles.
●Still in homologous pairs
Anaphase I
●The spindle guides the movement of the chromosomes toward the poles●Sister chromatids remain
attached●Move as a unit towards the
same pole
●The homologous chromosomes are separated to opposite poles
Telophase I
●This is the end of Meiosis I.
●The cytoplasm divides, forming two new daughter cells.
●Each of the newly formed cells has half the number of the parent cell’s chromosomes (23 unique chromosomes)
●but each chromosome is already replicated (sister chromatids) and the daughter cells are ready for Meiosis II
Cytokinesis
●Occurs simultaneously with Telophase I●Forms 2 daughter cells●Plant cells – cell plate●Animal cells – cleavage furrows
●NO FURTHER REPLICATION OF GENETIC MATERIAL (S Phase) PRIOR TO THE SECOND DIVISION OF MEIOSIS
Meiosis II : Separates sister chromatids
●There is no Interphase.
●Results in 4 haploid daughter cells (gametes)
Prophase II
●Each of the daughter cells forms a spindle, and the sister chromatids move toward the equator
Anaphase II
●The sister chromatids finally separate
●The sister chromatids of each pair move toward opposite poles●Now individual chromosomes,
we no longer call them chromatids!
Telophase II and Cytokinesis
●Nuclei form at opposite poles of the cell and cytokinesis occurs
●After completion of cytokinesis there are four daughter cells ●All are haploid (n)●This is the whole point of
meiosis!
One Way Meiosis Makes Lots of Different Sex Cells (Gametes) – Independent AssortmentIndependent assortment produces 2n distinct gametes, where n = the number of unique chromosomes.
That’s a lot of diversity by this mechanism alone.
In humans, n = 23 and 223 = 8388608.
Another Way Meiosis Makes Lots of Different Sex Cells – Crossing-Over
Crossing-over multiplies the already huge number of different gamete types produced by independent assortment.
The Key Difference Between Mitosis and Meiosis is the Way Chromosomes Uniquely Pair and Align in
Meiosis
Mitosis The first (and distinguishing) division of meiosis