the practice of korean medicine: an overview of clinical ... · the practice of korean medicine: an...

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Advance Access Publication 3 August 2005 eCAM 2005;2(3)325–352 doi:10.1093/ecam/neh102 Review The Practice of Korean Medicine: An Overview of Clinical Trials in Acupuncture Yong-Suk Kim 1 , Hyungjoon Jun 1 , Younbyoung Chae 2 , Hi-Joon Park 3 , Bong Hyun Kim 4 , Il-Moo Chang 4 , Sung-keel Kang 5 and Hye-Jung Lee 2 1 Department of Acupuncture and Moxibustion, College of Oriental Medicine, Kangnam Korean Hospital, 2 Department of Oriental Medical Science, Graduate School of East-West Medical Science, 3 Department of Meridian and Acupuncture, College of Korean Medicine, Kyung Hee University, 4 Natural Products Research Institute, Seoul National University, Seoul, South Korea and 5 Department of Acupuncture and Moxibustion, College of Oriental Medicine, Kyung Hee University, South Korea Acupuncture, one of the Oriental medical therapeutic techniques that can be traced back at least 2500 years, is growing in popularity all over the world. Korea has continued to develop its own unique tradition of medicine throughout its long history, and has formed different types of acupuncture methods. The purpose of this review is to summarize clinical case studies in acupuncture and related therapies, such as acupressure, electric acupuncture, auricular acupuncture and moxibustion in Korea. A survey of Korean journals revealed that a total of 124 studies were published from 1983 to 2001. Results obtained from the survey showed that most clinical studies using acupuncture, electric acupunc- ture, moxibustion and other traditional therapies could alleviate a relatively broad range of medical prob- lems. However, it should be emphasized that almost all clinical case studies published in various local journals did not follow the ‘good clinical practice’ with respect to regulatory aspects. Since they were not conducted using the randomized double-blinded controls with a large sample size, all the results should be considered as therapeutic indications. This review is an attempt to show the scope of acupunc- ture in our country and the kind of diseases, after many years of clinical experience, that were deemed valid targets for clinical trials. Keywords: acupuncture – clinical study – Korean acupuncture Introduction Acupuncture, one of the Oriental medical therapeutic tech- niques inherited from ancient East Asia, is gaining popularity in the West as an alternative and complementary therapeutic intervention (1). Acupuncture is now being used in Western medicine to treat postoperative-induced and chemotherapy- induced nausea and vomiting, postoperative dental pain, drug addiction, stroke rehabilitation and asthma (2). Korea has continued to develop its own unique traditional medicine throughout its long history, and has formed different types of acupuncture methods, apart from those of traditional Chinese medicine. An individualized approach based on constitutional energy traits and practical approaches applying new thera- peutic modalities have been developed for treatment of disorders (3). A large number of clinical studies using acupuncture have been performed to demonstrate its efficacy for many kinds of diseases, such as pain (headache, facial pain, neck pain, shoul- der pain, lower back pain and knee pain), stroke, facial palsy and other diseases in Korea. A wide range of control groups were used in these studies. Acupuncture and acupuncture- related therapies have been compared with various forms of control acupuncture, standard care, no treatment, baseline conditions and placebo acupuncture. These inconsistencies For reprints and all correspondence: Hye-Jung Lee, KMD, PhD, Department of Oriental Medical Science, Graduate School of East-West Medical Science, Kyung Hee University, 1 Seochonri, Kiheungeup, Younginshi, Kyungkido 449-701, South Korea. Tel: þ82-31-201-2173; Fax: þ82-31-206-9731; E-mail: [email protected] Ó The Author (2005). Published by Oxford University Press. All rights reserved. The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact [email protected]

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Page 1: The Practice of Korean Medicine: An Overview of Clinical ... · The Practice of Korean Medicine: An Overview of Clinical Trials in Acupuncture Yong-Suk Kim1, ... cupping therapy and

Advance Access Publication 3 August 2005 eCAM 2005;2(3)325–352

doi:10.1093/ecam/neh102

Review

The Practice of Korean Medicine: An Overview of Clinical Trialsin Acupuncture

Yong-Suk Kim1, Hyungjoon Jun1, Younbyoung Chae2, Hi-Joon Park3, Bong Hyun Kim4,Il-Moo Chang4, Sung-keel Kang5 and Hye-Jung Lee2

1Department of Acupuncture and Moxibustion, College of Oriental Medicine, Kangnam Korean Hospital,2Department of Oriental Medical Science, Graduate School of East-West Medical Science,3Department of Meridian and Acupuncture, College of Korean Medicine, Kyung Hee University,4Natural Products Research Institute, Seoul National University, Seoul, South Korea and5Department of Acupuncture and Moxibustion, College of Oriental Medicine, Kyung Hee University, South Korea

Acupuncture, one of the Oriental medical therapeutic techniques that can be traced back at least

2500 years, is growing in popularity all over the world. Korea has continued to develop its own unique

tradition of medicine throughout its long history, and has formed different types of acupuncture

methods. The purpose of this review is to summarize clinical case studies in acupuncture and related

therapies, such as acupressure, electric acupuncture, auricular acupuncture and moxibustion in Korea.

A survey of Korean journals revealed that a total of 124 studies were published from 1983 to 2001.

Results obtained from the survey showed that most clinical studies using acupuncture, electric acupunc-

ture, moxibustion and other traditional therapies could alleviate a relatively broad range of medical prob-

lems. However, it should be emphasized that almost all clinical case studies published in various local

journals did not follow the ‘good clinical practice’ with respect to regulatory aspects. Since they were

not conducted using the randomized double-blinded controls with a large sample size, all the results

should be considered as therapeutic indications. This review is an attempt to show the scope of acupunc-

ture in our country and the kind of diseases, after many years of clinical experience, that were deemed

valid targets for clinical trials.

Keywords: acupuncture – clinical study – Korean acupuncture

Introduction

Acupuncture, one of the Oriental medical therapeutic tech-

niques inherited from ancient East Asia, is gaining popularity

in the West as an alternative and complementary therapeutic

intervention (1). Acupuncture is now being used in Western

medicine to treat postoperative-induced and chemotherapy-

induced nausea and vomiting, postoperative dental pain, drug

addiction, stroke rehabilitation and asthma (2). Korea has

continued to develop its own unique traditional medicine

throughout its long history, and has formed different types of

acupuncture methods, apart from those of traditional Chinese

medicine. An individualized approach based on constitutional

energy traits and practical approaches applying new thera-

peutic modalities have been developed for treatment of

disorders (3).

A large number of clinical studies using acupuncture have

been performed to demonstrate its efficacy for many kinds of

diseases, such as pain (headache, facial pain, neck pain, shoul-

der pain, lower back pain and knee pain), stroke, facial palsy

and other diseases in Korea. A wide range of control groups

were used in these studies. Acupuncture and acupuncture-

related therapies have been compared with various forms of

control acupuncture, standard care, no treatment, baseline

conditions and placebo acupuncture. These inconsistencies

For reprints and all correspondence: Hye-Jung Lee, KMD, PhD, Departmentof Oriental Medical Science, Graduate School of East-West Medical Science,Kyung Hee University, 1 Seochonri, Kiheungeup, Younginshi, Kyungkido449-701, South Korea. Tel: þ82-31-201-2173; Fax: þ82-31-206-9731;E-mail: [email protected]

� The Author (2005). Published by Oxford University Press. All rights reserved.

The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open accessversion of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Pressare attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entiretybut only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact [email protected]

Page 2: The Practice of Korean Medicine: An Overview of Clinical ... · The Practice of Korean Medicine: An Overview of Clinical Trials in Acupuncture Yong-Suk Kim1, ... cupping therapy and

make the task of designing and performing systematic reviews

or meta-analyses more difficult. However, non-controlled

clinical trials might also be useful for the overview that they

provide of what is known so far, with data that may inform

future research. This review is an attempt to show a variety

of applications for acupuncture treatments performed by the

traditional Korean medical sector.

Clinical Studies Using AcupunctureTreatment in Korea

Acupuncture for Pain

Headache

Lee and Kim (4) analyzed the effect of acupuncture treatment

at trigger points in 27 patients with headache. Lee et al. (5)

compared the effect of acupuncture at trigger points with the

effect of acupuncture at remote acupuncture points in patients

who were diagnosed as having tension-type headaches. A clin-

ical study of auricular acupuncture was also done in 55 patients

with headaches (6). Clinical studies of acupuncture and

auricular acupuncture for tension-type headaches were also

performed (7,8) (Table 1).

Facial Pain

Temporomandibular disorder (TMD) is a musculoskeletal

problem of the masticatory system and is quite commonly

treated by acupuncture in the general population. It was repor-

ted that 8 and 10 cases, respectively, of TMD were treated

by acupuncture (9,10). Wang et al. (11) treated by Dong-Qi

acupuncture and subjectively evaluated TMD and facial pain

(Table 2).

Neck Pain

Chun and Lee (12) treated patients with chronic neck pain by

using electric acupuncture (0.3 · 40 mm, 3.5–12 Hz, 9 V).

Kim and Lee (13) compared the group treated by both acu-

puncture and manipulation (chuna) treatment with the group

only treated by acupuncture. A clinical study investigated the

clinical applications of Oriental medical therapies including

acupuncture treatment together with herbal therapy and hot

pack for patients complaining of cervical pain caused by traffic

accidents (14). It was reported that acupuncture treatment was

effective in 50 patients with cervical pain (15). Lee and Lee

(16) treated 25 patients with neck pain with electric acupunc-

ture together with herbal therapy, cupping therapy and hot

pack. It was also reported that acupuncture was effective in

treating 50 patients with herniated cervical disc (17) (Table 3).

Shoulder Pain

Forty-three patients suffering from frozen shoulder during

physical exercise were treated by acupuncture, moxibustion

and electric acupuncture, and evaluated with Apley scratch Table

1.

Acu

pu

nct

ure

for

hea

dac

he

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

unct

ure

Len

gth

and

nu

mb

ero

fT

xO

ther

trea

tmen

tsA

sses

smen

tR

esult

so

fac

up

unct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

Byun

and

Ahn

(6)

Hea

dac

he

55

AA

2/1

wee

kvar

ious

tim

esN

one

Cla

ssif

ied

into

five

gro

ups

(exce

llen

t,g

oo

d,

mo

der

ate,

slig

ht

and

un

chan

ged

)b

ycl

inic

alev

aluat

ion

Rec

over

ed,

9.1

%;

go

od,

36

.4%

;m

od

erat

e,2

7.3

%;

slig

ht,

12

.7%

;u

nch

ang

ed,

4.5

%

N/A

Kim

and

Kim

(7)

Str

ain

edh

ead

ach

e7

5C

A(0

.25·

40

mm

),A

A(1

/2–4

day

s)1

5m

inN

on

eC

lass

ifie

din

toth

ree

gro

ups

(exce

llen

t,fa

iran

du

nch

ang

ed)

by

clin

ical

eval

uat

ion

Ex

cell

ent,

12

%;

fair

,6

2.7

%;

un

chan

ged

,5

.3%

N/A

Lee

and

Kim

(4)

Hea

dac

he

27

Tri

gger

poin

tT

xS

tim

ula

tion

by

nee

dle

or

15

min

var

iou

sti

mes

Infr

ared

Cla

ssif

ied

into

fiv

eg

rou

ps

(go

od

,fa

ir,

po

or,

bad

and

un

kno

wn

)b

ycl

inic

alev

aluat

ion

Go

od

,2

5.9

3%

;fa

ir,

48

.15

%;

po

or,

7.4

1%

;b

ad,

3.7

0%

;u

nk

no

wn

,1

4.8

1%

N/A

Kim

etal.

(8)

Ch

ron

ich

ead

ach

e3

6C

A(0

.25·

30

mm

),A

A(2

/1w

eek

)2

0m

in3

/1w

eek

for

4w

eek

sN

on

eA

sses

smen

tth

rou

gh

qu

esti

on

nai

res

and

self

-rat

ing

hea

dac

he

sco

reC

Aan

dA

Aw

ere

effe

ctiv

eT

xo

nlo

ng-t

erm

anal

ges

ics-

abuse

dh

ead

ach

ep

atie

nts

,es

pec

iall

yte

nsi

on-t

yp

eh

ead

ach

eg

rou

p

P<

0.0

5

Lee

etal.

(5)

Ten

sio

n-t

yp

eh

ead

ach

e4

02

0T

rigg

erp

oin

tT

xS

tim

ula

tio

nb

yn

eed

leo

r1

0m

info

r4

tim

esIn

frar

ed,

exer

cise

VA

SN

od

iffe

ren

ceb

etw

een

gro

up

sN

/S

20

Rem

ote

acu

pu

nct

ure

po

int

nee

dli

ng:

Do

ng

-si

acu

pu

nct

ure

10

min

for

4ti

mes

CA

,cl

assi

cal

acu

pu

nct

ure

;A

A,

auri

cula

rac

up

un

ctu

re;

Tx

,tr

eatm

ent;

VA

S,

vis

ual

anal

og

sco

re;

N/A

,n

ot

app

lica

ble

;N

/S,

no

tsi

gn

ific

ant.

326 Acupuncture in Korea

Page 3: The Practice of Korean Medicine: An Overview of Clinical ... · The Practice of Korean Medicine: An Overview of Clinical Trials in Acupuncture Yong-Suk Kim1, ... cupping therapy and

test. A total of 16.3% of them reported that the results of treat-

ment were excellent and 30.2% of them reported that they

were good (18). Cho and Lee (19) showed the correlation

between digital infrared thermography image (DITI) data and

changes in clinical symptoms after acupuncture treatment in

patients with frozen shoulder (Table 4) (Fig. 1).

Low Back Pain

A series of 20 cases with lumbar herniated disc disease were

treated by acupuncture (20). It was reported that acupuncture

and herbal medicine alleviated the symptoms of the herniation

of lumbar intervertebral disc (21–25). It was also reported that

bee venom acupuncture (BVA) was beneficial for treating

herniated intervertebral disc (HIVD) (26). Park et al. (27) per-

formed clinical studies using acupuncture and manipulation

treatment on 30 HIVD patients. It was found that microcurrent

electrical neuromuscular stimulation was significantly effect-

ive in decreasing the visual analog scores of patients with

lower back pain (28). Park et al. (29) reported a clinical study

of the stability of the lumbosacral angle of 69 patients suffer-

ing from lower back pain. The morphological changes were

demonstrated by computed tomographic scan examination

of acute HIVD patients who underwent Oriental medical

treatment (30).

A clinical study compared acupuncture with electric

acupuncture for patients with HIVD (31). Park and Lee (32)

compared the effect of electric acupuncture with the effect of

Dong-si acupuncture on patients with HIVD. Lee and Hwang

(33) compared electric acupuncture with electric acupuncture

and Saam acupuncture in HIVD patients. Yoon et al. (34) com-

pared acupuncture at A-shi points with acupuncture on acu-

puncture points in HIVD patients. Chae et al. (35) compared

conventional acupuncture with Eight constitution acupuncture

and demonstrated that Eight constitutional acupuncture

was more beneficial than conventional acupuncture for the

treatment of HIVD patients.

Electric acupuncture decreased the frequency of radiating

pain in lumbar spondylosis (36). Clinical studies evaluated

Oriental medical treatment and manipulation therapy in

patients with scoliosis (37,38). Kim (39) reported the results

of 96 patients suffering from sciatica with lower back pain

treated by acupuncture and herbal medicine. It was reported

that acupuncture, moxibustion and herbal medicine were

useful for acute back pain (40). Lee and Yin (41) also reported

a clinical study of BVA on ankylosing spondylitis. Lee et al.

(42) performed a clinical study on acupuncture for stable

thoracolumbar vertebral fractures. It was reported that

acupuncture, electric acupuncture, acupuncture at Hua-Tuo-

Jia-Ji-Xue were useful for the treatment of thoracolumbar

compression fracture (43–45). Han (46) treated degenerated

stenosis patients (37 cases), and Kim et al. (47) evaluated the

clinical results of the spondylolisthesis patients treated by

Oriental medical methods.

Lee et al. evaluated acupuncture treatment for HIVD

and stable compression fracture patients using DITI (48,49).Table

2.

Acu

pu

nct

ure

for

faci

alp

ain

(tem

po

rom

and

ibu

lar

join

td

isea

se)

Au

tho

rn

ame(

s)N

um

ber

of

po

ints

Ty

pe

of

acup

un

ctu

reL

eng

than

dn

um

ber

of

Tx

Oth

ertr

eatm

ents

Ass

essm

ent

Res

ult

so

fac

up

unct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

Kim

and

Kim

(9)

8C

AV

ario

us;

3–4

tim

esIn

frar

ed,

self

-str

etch

teac

hin

gan

dH

erb

-med

Cli

nic

alev

aluat

ion

Rep

ort

of

each

pat

ient

(acu

pu

nct

ure

trea

tmen

tw

asef

fect

ive)

N/A

Byu

net

al.

(10

)1

0C

A(0

.25·

30

mm

),A

A,

EA

and

dep

leti

on

of

blo

od

(so

me

case

s)

15

min

1/2

day

sv

ario

us

tim

esU

S,

aqu

aliz

erm

ediu

msi

ze,

etc

Ex

amin

ech

ang

eso

fsy

mp

tom

s,X

-ray

and

DIT

I

Rep

ort

of

each

pat

ien

t(a

cup

un

ctu

retr

eatm

ent

was

effe

ctiv

e)

N/A

Wan

get

al.

(11

)4

0C

A(0

.3·

40

mm

)1

0m

in1

–2

/1w

eek

var

ious

tim

esD

on

g-Q

iac

up

un

ctu

retr

eatm

ent

(mo

ve

mo

uth

du

rin

gac

up

unct

ure

stim

ula

tio

n)

An

alyze

fun

ctio

nan

dcl

inic

alim

pro

vem

ent

(by

sub

ject

ive

asse

ssm

ent

pap

er)

Mo

sto

fth

em(q

ues

tio

nn

aire

sin

sub

ject

ive

asse

ssm

ent

pap

er)

wer

esi

gn

ific

antl

yim

pro

ved

P<

0.0

5,

P<

0.0

1

Her

b-m

ed,

her

bal

med

icin

e;E

A,

elec

tric

alac

up

un

ctu

re;

US

,u

ltra

sou

nd

;D

ITI,

dig

ital

infr

ared

ther

mo

gra

phic

imag

ing

.

eCAM 2005;2(3) 327

Page 4: The Practice of Korean Medicine: An Overview of Clinical ... · The Practice of Korean Medicine: An Overview of Clinical Trials in Acupuncture Yong-Suk Kim1, ... cupping therapy and

Table

3.

Acu

pu

nct

ure

for

cerv

ical

pai

n

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

unct

ure

Len

gth

and

nu

mb

ero

fT

xO

ther

trea

tmen

tsA

sses

smen

tR

esult

so

fac

up

un

ctu

reth

erap

yS

tati

stic

alan

alysi

s

Chu

nan

dL

ee(1

2)

Cer

vic

alp

ain

34

EA

(0.3

·4

0m

mlo

wfr

equen

t,3

.5–

12

Hz,

9V

)

15

min

var

iou

sti

mes

Infr

ared

,ch

un

aan

dH

erb-m

ed(s

om

eca

ses)

Cla

ssif

ied

into

four

gro

ups

(exce

llen

t,good,

fair

and

po

or)

by

chan

ge

of

sym

pto

ms,

RO

M,

ph

ysi

cal

exam

inat

ion

Ex

cell

ent,

11

.8%

;g

oo

d,

52

.9%

;fa

ir,

20

.6%

;p

oo

r,1

4.7

%

N/A

Lee

and

Lee

(16

)N

eck

pai

n2

5C

A,

EA

(1–

25

Hz,

con

stan

to

rin

term

itte

nt)

20

–30

min

var

iou

sti

mes

Her

b-m

ed,

chu

na

(10

min

,4

/1w

eek

)an

dcu

pp

ing

ther

apy,

ES

T,

TE

NS

,m

icro

wav

e,h

ot

pac

k,

C-t

ract

ion

,et

c.

Cla

ssif

ied

into

four

gro

ups

(exce

llen

t,good,

fair

and

po

or)

by

chan

ge

of

sym

pto

ms,

RO

M,

ph

ysi

cal

exam

inat

ion

Ex

cell

ent,

16

%;

go

od,

44

%;

fair

,2

4%

;fa

ilure

,1

6%

N/A

Lee

etal.

(15

)C

erv

ical

pai

n5

0C

A2

0–

30

min

var

iou

sti

mes

Her

b-m

ed,

neg

ativ

e(1

/1d

ay),

chu

na

(10

per

son

,2

–3

/1w

eek

)

Cla

ssif

ied

into

four

gro

ups

(exce

llen

t,good,

fair

and

fail

ure

)b

ych

anges

of

sym

pto

ms,

RO

Man

dp

hy

sica

lex

amin

atio

n

Ex

cell

ent,

6%

;g

oo

d,

32

%;

fair

,5

6%

;fa

ilure

,6

%

N/A

Cho

iet

al.

(14

)C

erv

ical

pai

n(b

ytr

affi

cac

ciden

t)

52

CA

No

tst

ated

Her

b-m

ed,

Ori

enta

lP

hy-T

x(h

ot

pac

k,

TE

NS

,S

SP

,N

egat

ive,

US

,tr

acti

on,

etc.

),ch

un

a,C

–H

pas

(so

me

case

s)

Cla

ssif

ied

into

five

gro

ups

(exce

llen

t,im

pro

ved

,m

ild

imp

roved

and

fail

ure

)b

ych

ang

eso

fsy

mp

tom

san

dR

OM

Ex

cell

ent,

17

.31

%;

imp

rov

ed,

40

.38

%;

mil

dim

pro

ved

,3

2.6

9%

;fa

ilure

,9

.62%

N/A

Lee

etal.

(17

)H

NP

of

C-s

pin

e5

0C

A(0

.25·

30

mm

),d

eple

tio

no

fb

loo

d2

8m

ind

aily

var

iou

sti

mes

Cer

vic

altr

acti

on

,ce

rvic

alco

llar

,et

c.C

lass

ifie

din

tofo

ur

gro

ups

(exce

llen

t,good,

fair

and

po

or)

by

crit

eria

of

Mar

tin

A.N

.

Ex

cell

ent,

70

%;

go

od,

20

%;

fair

,6

%;

po

or,

4%

N/A

Kim

and

Lee

(13

)N

eck

pai

n7

23

2

40

CA

(0.2

40

mm

)

Sam

e

15

min

1/2

day

s6

tim

esS

ame

Ch

un

a(v

ario

us

met

ho

ds,

1/2

day

s,6

tim

es)

No

ne

Mea

sure

VA

S,

RO

MG

rou

ptr

eate

db

yac

up

un

ctu

rew

ith

chu

na

was

bet

ter

than

gro

up

trea

ted

by

on

lyac

up

un

ctu

rein

the

deg

ree

of

imp

rovem

ent

inp

ain

and

RO

M

P<

0.0

01

RO

M,ra

ng

eo

fm

oti

on

;P

hy

-Tx

,ph

ysi

cal

ther

apy

;T

EN

S,t

ran

scuta

no

us

elec

tric

aln

erv

est

imu

lati

on

;E

ST

,el

ectr

ical

stim

ula

tion

ther

apy;

HN

P,h

ern

iate

dn

ucl

eus

pu

lpo

sus;

SS

P,si

lver

spik

ep

oin

t;L

BP

,L

ow

bac

kpai

n;

IFC

,in

terf

eren

cial

curr

ent;

FE

S,

funct

ional

elec

tric

alst

imula

tion.

328 Acupuncture in Korea

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Cho and Kim (50) compared the acupuncture with electric

acupuncture for HIVD patients using DITI. Hur et al. (51)

investigated changes in the clinical symptoms of patients

with spondylolisthesis after acupuncture treatment and evalu-

ated alterations in DITI. A clinical study also reported a rela-

tionship between cigarette smoking and the result of Oriental

medical treatment for lower back pain (52). Heo and co-

workers studied the treatment of lower back pain and sciatica

and found some correlation in the rate of alleviation with

alterations in Moire topography (53,54) (Table 5).

Knee Joint Pain

It was reported that acupuncture was useful for the treatment of

degenerative arthritis of knee joints (55–57). Woo et al. (58)

evaluated the clinical effect of acupuncture on microtraumatic

injuries of the knee joint. Kim and Lee compared acupuncture

with BVA for osteoarthritis (59,60). Hwang et al. (61) meas-

ured the change of C-reactive protein (CRP), erythrocyte

sedimentation rate (ESR) and rheumatoid arthritis (RA) factor,

and the satisfactory assessment after BVA treatment in RA

patients. Hwang (62) treated RA patients with herbal acupunc-

ture (HA) and evaluated CRP, ESR, RA factor and immuno-

globulin G and M (Table 6).

Other Painful Diseases

Electrical acupuncture stimulation was very useful to relieve

pain that had not responded to various conventional medica-

tions including nerve blocks, neurosurgical intervention and

neuropolitics (63). Cho et al. (64) compared acupuncture treat-

ment and analgesics in postthoracotomy pain control. It was

reported that venesection, a therapeutic method of sucking

out non-physiological blood, alleviated pain induced by blood

circulation dysfunction (65). Kim et al. (66) compared acu-

puncture treatment with trigger point treatment in ankle sprain

patients. Bang et al. (67) carried out a clinical study on patients

with humeral lateral epicondylitis or tennis elbow. Seung and

Ahn (68) investigated the effect of moxibustion on the immune

activity in the treatment of patients. Acupuncture treatment

was very beneficial for acute gout (69). It was also demon-

strated that acupuncture at acupoints on the non-injured side

were as effective as acupuncture at acupoints on the injured

side in ankle sprain patients (70) (Table 7) (Fig. 2).

Acupuncture for Stroke

Stroke

Ha et al. (71) reported a clinical study of acupuncture and scalp

acupuncture on stroke patients (29 cases). Lee et al. (72) evalu-

ated the change of blood pressure and body temperature of the

stroke patients after venesection at Sybsun points, 10 acupoints

located at the tips of all fingers and demonstrated that venesec-

tion at Sybsun points could alleviate hypertension in stroke

patients. Park et al. (73) examined electrical stimulation at

GV26 and CV24 on blood pressure, heart rate and cerebralTable

4.

Acu

pu

nct

ure

for

sho

uld

erp

ain

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

un

ctu

reL

eng

than

dn

um

ber

of

Tx

Oth

ertr

eatm

ents

Ass

essm

ent

Res

ult

so

fac

up

un

ctu

reth

erap

yS

tati

stic

alan

aly

sis

Par

kan

dL

ee(1

8)

Fro

zen

sho

uld

er4

3C

A(0

.35·

40

mm

),E

A(2

Hz,

con

tin

uo

us)

,d

irec

tm

ox

ibu

stio

n

20

–3

0m

in3

–5

/1

wee

kv

ario

us

tim

es

Her

b-m

edC

lass

ifie

din

tofo

ur

gro

ups

(exce

llen

t,good,

fair

and

po

or)

by

chan

ges

of

sym

pto

ms

and

Ap

ley

scra

tch

test

Ex

cell

ent,

16

.3%

;g

oo

d,

34

.8%

;fa

ir,

18

.6%

;fa

ilure

,3

0.2

%

N/A

Ch

oan

dL

ee(1

9)

Fro

zen

sho

uld

er2

3C

A(0

.25·

30

mm

),in

dir

ect

mox

ibu

stio

n,

fire

nee

dle

20

–3

0m

ind

aily

var

ious

tim

esH

erb-m

ed,

ICT

,U

S,

ho

tp

ack

Cla

ssif

ied

into

fou

rgro

ups

(exce

llen

t,good,

fair

and

po

or)

by

chan

ges

of

sym

pto

ms

and

DIT

I

DIT

Iw

asv

alu

able

inth

eev

alu

atio

no

fth

erap

euti

cef

fect

of

acu

pu

nct

ure

Tx

N/A

ICT

,in

terf

eren

tial

curr

ent

ther

apy.

eCAM 2005;2(3) 329

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blood flow (CBF) in ischemic stroke patients with transcranial

doppler sonography. Ahn et al. (74) investigated change in

24 h blood pressure after auricular acupuncture treatment in

stroke patients using an ambulatory blood pressure monitor.

Kang et al. (75) compared acupuncture at ST36 and LI11

with stimulation at non-acupoints near these acupoints for the

modulation of hypertension of acute stroke patients. Moon

et al. (76) compared acupuncture at ipsilateral points with

that at contralateral points on the cerebral blood flow (CBF)

in ischemic stroke patients (Table 8).

Poststroke Diseases

Electric acupuncture could alleviate shoulder pain in

cerebrovascular attack patients (77). It was demonstrated that

BVA at LI15 and SI10 decreased visual analog scale of pain

severity and increased painless passive range of motion of

shoulder eternal rotation in hemiplegic shoulder pain

patients (78). Kang and Baik (79) compared the therapeutic

value of transcutanous electrical nerve stimulation with inter-

ferential current therapy, infrared or hot pack treatments for

shoulder pain in cerebrovascular attack patients. Lee and Lee

(80) evaluated the effect of acupuncture and electric acupunc-

ture on shoulder hand syndrome by using DITI. Kang et al.

(81) examined the balanced bladder time and residual urine

volume and demonstrated the clinical efficacy of moxibustion

at CV3, CV4 and CV6 in patients with voiding dysfunction

after a cerebrovascular accident (Table 9).

Acupuncture for Facial Palsy

Acupuncture treatment was beneficial in 72 cases of patients

with facial paralysis (82). Moreover, electric acupuncture

was better than needling in the treatment of patients with

peripheral facial nerve paralysis (83). The effect of Hominis

placenta acupuncture, a kind of HA, on Bell’s palsy was repor-

ted (84). It was demonstrated that Saam acupuncture at liver

and stomach tonification points could treat peripheral facial

palsy (85). Cho et al. observed the change of clinical symp-

toms and DITI, showing the benefits of acupuncture and

herbal medicine in patients with Bell’s palsy (86,87).

Figure 1. ‘Acu-moxibustion Being Easy to Learn’, published in the Ching dynasty, 18th century. (Courtesy of Dr Kim Nam-Il, Department of Medical History,

College of Oriental Medicine, Kyung Hee University, Seoul, South Korea.)

330 Acupuncture in Korea

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Table

5.

Acu

pu

nct

ure

for

low

bac

kp

ain

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

unct

ure

Len

gth

and

nu

mb

ero

fT

xO

ther

trea

tmen

tsA

sses

smen

tR

esult

so

fac

up

unct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

Kim

and

Cho

i(2

0)

HN

Po

fL

-sp

ine

20

CA

15

min

1/2

day

sv

ario

us

tim

esN

on

eC

lass

ifie

din

tofi

ve

gro

ups

(exce

llen

t,good,

mod

erat

e,sl

igh

tan

dn

ot

imp

roved

)b

ycl

inic

alev

alu

atio

n

Ex

cell

ent,

25

%;

go

od,

20

%;

mod

erat

e,1

0%

;sl

igh

t,2

0%

;n

ot

imp

roved

,2

5%

N/A

Kim

and

Chae

(36

)L

BP

and

scia

tica

96

CA

(0.2

40

mm

)1

5m

in1

/1–

2d

ays

var

ious

tim

esN

egat

ive,

carb

on

,in

frar

ed,

ICT

,h

ot

pac

k,

trac

tio

n,

etc.

(so

me

case

s)

Cla

ssif

ied

into

fou

rgro

ups

(exce

llen

t,good,

fair

and

po

or)

by

clin

ical

eval

uat

ion

Ex

cell

ent,

26

%;

go

od,

35

.4%

;fa

ir,

28

.1%

;p

oo

r,1

0.4

%

N/A

Lee

etal.

(42

)S

tab

leth

ora

colu

mb

arv

erte

bra

lfr

actu

re

20

Acute

stage

Dep

leti

on

of

blo

od

(A-s

hi

po

ints

,d

aily

),af

terw

ard

CA

No

tst

ated

Her

b-m

ed,

ICT

,U

S,

ho

tp

ack

,K

nig

ht

tay

lor

kin

sup

po

rt,

Boh

ler

exer

cise

Cla

ssif

ied

into

fou

rgro

ups

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

clin

ical

eval

uat

ion

Ex

cell

ent,

30

%;

go

od,

60

%;

fair

,5

%;

po

or,

5%

N/A

Chronic

stage

CA

,af

terw

ard

ind

irec

tm

ox

ibu

stio

n(s

ame

site

,3

pie

ce)

15

min

var

ious

tim

es

Lee

(48

)H

NP

of

L-s

pin

e2

6C

A2

0m

ind

aily

for

4w

eek

sH

erb

-med

Cla

ssif

ied

into

fou

rgro

ups

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

chan

ges

of

sym

pto

ms

and

DIT

I

Ex

cell

ent,

23

%;

go

od,

73

%;

fair

,4

%;

po

or,

0%

N/A

Han

(46

)D

egen

erat

ive

lum

bar

sten

osi

s3

7E

A(0

.3·

50

mm

),H

A(n

utr

ien

td

uct

s0

.1–0

.2m

l),

ind

irec

tm

ox

idu

stio

n(5

pie

ce)

15

–20

min

1/1

–2

day

sv

ario

us

tim

es

Her

b-m

ed,

neg

ativ

e(d

aily

)C

lass

ifie

din

tofo

ur

gro

ups

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

clin

ical

eval

uat

ion

Ex

cell

ent,

13

.5%

;g

oo

d,

56

.8%

;fa

ir,

8.1

%;

po

or,

21

.6%

N/A

Hu

ret

al.

(51

)S

po

nd

ylo

list

hes

is2

2C

A(0

.25·

30

mm

),in

dir

ect

mo

xib

ust

ion

(pai

nsi

te),

fire

nee

dle

20

–30

min

dai

lyv

ario

us

tim

esIF

C,

US

,h

ot

pac

k,

etc.

Cla

ssif

ied

into

fou

rgro

ups

(exce

llen

t,good,

fair

and

po

or)

by

chan

ges

of

sym

pto

ms

and

DIT

I

Ex

cell

ent,

27

.25

%;

go

od,

54

.6%

;fa

ir,

13

.65

%;

po

or,

4.5

%

N/A

Kim

etal.

(47

)S

po

nd

ylo

list

hes

is2

8C

A(0

.3·

40

mm

),E

A(1

4H

zco

nst

ant)

,m

ox

ibu

stio

n

15

–20

min

var

ious

tim

esH

erb

-med

,in

frar

ed,

ho

tp

ack

,IC

T,

US

,cu

pp

ing

ther

apy,

etc.

Cla

ssif

ied

into

fou

rgro

ups

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

clin

ical

eval

uat

ion

Ex

cell

ent,

10

.7%

;g

oo

d,

60

.7%

;fa

ir,

25

%;

po

or,

3.6

%

N/A

Mu

net

al.

(30

)H

NP

of

L-s

pin

e1

6C

A,

indir

ect

mo

xib

ust

ion

(3p

iece

/1d

ay)

30

min

dai

lyv

ario

us

tim

esH

erb

-med

,cu

pp

ing

ther

apy

(5m

in),

Wes

tern

med

icin

e

Mea

sure

her

nia

tion

rate

thro

ug

hf/

uco

mp

ute

dto

mo

gra

ph

yaf

ter

5–

7y

ears

Th

ela

rges

th

ern

iati

on

sw

ere

tho

seth

ath

adth

eg

reat

est

ten

den

cyto

dec

reas

ein

size

N/A

Lim

etal.

(40

)A

cute

bac

kp

ain

34

CA

15

–30

min

2/1

day

var

ious

tim

esW

hu

alla

k-t

ang

(ov

er7

day

s),

cup

pin

gth

erap

y,

exer

cise

Cla

ssif

ied

into

fou

rgro

ups

(exce

llen

t,good,

fair

and

po

or)

by

clin

ical

eval

uat

ion

,m

easu

reA

ST

,A

LT

,A

LP

Ex

cell

ent,

29

.4%

;g

oo

d,

67

.7%

;fa

ir,

2.9

%;

po

or,

0%

N/A

eCAM 2005;2(3) 331

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Table

5.Continued

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

unct

ure

Len

gth

and

nu

mb

ero

fT

xO

ther

trea

tmen

tsA

sses

smen

tR

esult

so

fac

up

un

ctu

reth

erap

y

Sta

tist

ical

anal

ysi

s

Jinet

al.

(37

)S

coli

osi

s1

2C

AN

ot

stat

edC

hu

na

(dai

ly),

Her

b-m

ed,

ICT

,U

S,

etc.

Mea

sure

corr

ecti

on

rate

thro

ug

hC

ob

b’s

ang

le(X

-ray

)

Sy

mpto

ms"

,sc

oli

osi

san

gle",

rota

tio

nd

egre

e",!

corr

ecti

on

rate#

N/A

Jan

get

al.

(21

)H

NP

of

L-s

pin

e3

0C

A(0

.3·

40

mm

and

0.4

·8

0m

m)

15

–2

0m

ind

aily

var

iou

sti

mes

Her

b-m

ed,

ho

tp

ack

,IC

T,

ES

T,

trac

tion,

cup

pin

gth

erap

y,

Chu

na

(co

x),

etc.

Cla

ssif

ied

into

four

gro

ups

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

chan

ges

of

sym

pto

ms

and

DIT

I

Ex

cell

ent,

20

%;

go

od,

43

.3%

;fa

ir,

30

%;

po

or,

6.6

6%

N/A

Par

kan

dA

hn

(31

)H

NP

of

L-s

pin

e4

42

2C

A(0

.3·

40

mm

),d

eple

tio

no

fb

loo

d(A

-shi

po

ints

.5

–1

0cc

),E

A(3

.5–

12

Hz,

9V

,1

5m

in)

15

min

dai

lyv

ario

us

tim

esT

EN

S,

infr

ared

,tr

acti

on

,h

ot

pac

kC

lass

ifie

din

tofo

ur

gro

ups

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

clin

ical

eval

uat

ion

EA

gro

up

wer

em

ore

effe

ctiv

eth

anC

Ag

rou

p

N/A

22

CA

(0.3

·4

0m

m),

dep

leti

on

of

blo

od

(A-s

hi

po

ints

.5

–1

0cc

)

Sam

e

Ch

oan

dK

im(5

0)

HN

Po

fL

-sp

ine

40

22

18

CA

(0.3

·4

0m

m),

EA

(3.5

–12

Hz

at9

Vfo

r1

5m

in)

CA

(0.3

·4

0m

m)

25

min

dai

lyv

ario

us

tim

es

Sam

e

Her

b-m

ed,

IFC

,U

S,

cup

pin

gth

erap

y,

ho

to

ric

ep

ack

Cla

ssif

ied

into

four

gro

ups

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

chan

ges

of

sym

pto

ms

and

DIT

I

EA

gro

up

wer

em

ore

effe

ctiv

eth

anC

Ag

rou

p

N/A

Par

kan

dL

ee(3

2)

LB

Pan

dsc

iati

ca2

11

2D

on

g-s

iac

up

unct

ure

Tx

(0.3

·4

0m

mfo

r2

0–

30

min

),C

A(0

.3·

40

mm

for

40

–80

min

),E

A(2

.3–

3.6

Hz

at2

–6

V)

15

–2

5m

ind

aily

var

iou

sti

mes

Her

b-m

ed,

ho

tp

ack

,cu

pp

ing

ther

apy

,IC

T,

ES

T,

trac

tio

n,

etc.

Cla

ssif

ied

into

four

gro

ups

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

chan

ges

of

sym

pto

ms

and

ph

ysi

cal

exam

inat

ion

Do

ng

-si

acu

pu

nct

ure

(þC

EA

)g

rou

pw

ere

mo

reef

fect

ive

than

CA

(þE

A)

gro

up

N/A

9C

A(0

.3·

40

mm

40

–80

mm

),E

A(2

.3–

3.6

Hz

at2

–6

Vso

me

case

s)

Sam

e

Lee

and

Hw

ang

(33

)L

BP

and

scia

tica

28

14

Saa

mac

up

un

ctu

reT

x(0

.3·

40

mm

,fo

r2

0–

30

min

),C

A(0

.3·

40

–80

mm

),E

A(2

.3–

3.6

Hz)

15

–2

5m

ind

aily

(eac

h)

var

iou

sti

mes

Ho

tp

ack

,cu

pp

ing

ther

apy

,IC

T,

ES

T,

trac

tio

n,

Chu

na,

etc.

Cla

ssif

ied

into

four

gro

ups

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

chan

ges

of

sym

pto

ms

and

ph

ysi

cal

exam

inat

ion

Saa

mac

up

unct

ure

gro

up

(þC

EA

)w

ere

mo

reef

fect

ive

than

CA

(þE

A)

gro

up

N/A

14

CA

(0.3

·4

0–

80

mm

),E

A(2

.3–

3.6

Hz)

Sam

e

Lee

etal.

(25

)H

NP

of

L-s

pin

e6

02

7

33

CA

(0.2

30

mm

)

Sam

e

15

–2

0m

ind

aily

var

iou

sti

mes

Sam

e

ICT

,U

S,

TE

NS

,tr

acti

on

,h

ot

or

ice

pac

k(s

om

eca

ses)

Wes

tern

med

icin

ein

ject

ion

Cla

ssif

ied

into

four

gro

ups

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

clin

ical

eval

uat

ion

Gro

up

wit

hO

rien

tal-

Wes

tern

med

icin

ew

ere

mo

reef

fect

ive

than

gro

up

wit

hO

rien

tal

med

icin

e

N/A

332 Acupuncture in Korea

Page 9: The Practice of Korean Medicine: An Overview of Clinical ... · The Practice of Korean Medicine: An Overview of Clinical Trials in Acupuncture Yong-Suk Kim1, ... cupping therapy and

Yo

onet

al.

(34

)H

NP

of

L-s

pin

e3

01

5

15

CA

(0.3

·4

0–

80

mm

som

ep

oin

tsan

dA

-sh

ip

oin

t),

EA

(2.3

–3.5

Hz)

CA

(0.3

·4

0–

80

mm

som

ep

oin

ts),

EA

(2.3

–3.5

Hz)

15

–2

5m

ind

aily

(eac

h)

var

iou

sti

mes

15

–2

5m

ind

aily

var

iou

sti

mes

Ho

tp

ack

,cu

pp

ing

ther

apy

,IC

T,

ES

T,

trac

tio

n,

chu

na,

etc.

Cla

ssif

ied

into

four

gro

ups

(exce

llen

t,good,

fair

and

po

or)

by

chan

ges

of

sym

pto

ms

and

ph

ysi

cal

exam

inat

ion

A-s

hi

po

int

gro

up

(þC

EA

)w

ere

more

effe

ctiv

eth

anC

A(þ

EA

)g

rou

p

N/A

Ch

aeet

al.

(35

)H

NP

of

L-s

pin

e2

91

7C

A2

/1d

ay(f

irst

5d

ays)

1/1

day

(aft

er5

day

s)fo

r1

0d

ays

No

ne

Mea

sure

VA

SC

on

stit

uti

on

alac

up

un

ctu

reg

rou

pw

ere

mo

reef

fect

ive

than

CA

gro

up

P<

0.0

5

12

Cost

itu

tio

nal

acu

pu

nct

ure

2/1

day

(fir

st5

day

s)1

/1d

ay(a

fter

5d

ays)

for

10

day

s

Jeo

nget

al.

(52

)L

BP

40

28

12

Sm

oker

s,C

A(0

.25·

40

mm

),E

AN

on

-sm

ok

ers:

sam

e

20

–2

5m

ind

aily

var

iou

sti

mes

Sam

e

Cup

pin

gth

erap

y,

Her

b-m

ed,

ho

tp

ack

,T

EN

S,

ICT

,E

ST

,F

ES

Cla

ssif

ied

into

four

gro

ups

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

chan

ges

of

sym

pto

ms

and

ph

ysi

cal

exam

inat

ion

Sm

okin

g"!

effe

ctiv

enes

s#N

/S

So

nget

al.

(45

)T

ho

raco

lum

bar

com

pre

ssio

nfr

actu

re

50

25

CA

(0.3

·3

0m

mH

ua-

Tuo-J

ia-J

i-X

ue

acu

pu

nct

ure

(45�

ob

liq

ue)

and

som

ep

oin

ts)

15

–2

0m

ind

aily

var

iou

sti

mes

Cup

pin

gth

erap

y,

Her

b-m

ed,

ho

tp

ack

,IC

T,

TE

NS

,lu

mb

arb

elt

Cla

ssif

ied

into

four

gro

ups

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

chan

ges

of

sym

pto

ms

and

ph

ysi

cal

exam

inat

ion

Hu

a-T

uo-J

ia-J

i-X

ue

acup

un

ctu

reg

rou

pw

ere

mo

reef

fect

ive

than

CA

gro

up

N/A

25

CA

(0.3

·3

0m

mso

me

po

ints

)S

ame

Kim

etal.

(28

)L

BP

33

17

ME

NS

(0.2

40

mm

,B

24

–B

27

,6

40mA

,3

Hz)

15

min

1/3

day

s6

tim

esH

erb

-med

(4)

Mea

sure

VA

S,

RO

M,

OD

IM

EN

Sh

adan

effe

cto

nre

liev

ing

LB

PV

AS

(P<

0.0

5);

RO

M,

N/S

;O

DI,

N/S

16

CA

(0.2

40

mm

,B

24

–B

27

)S

ame

Heo

(38

)L

BP

29

21 8

Dis

cog

enic

:C

A(n

ot

stat

ed)

Sim

ple

bac

k:

CA

(no

tst

ated

)

No

tst

ated

No

tst

ated

Chu

na

(fle

xio

n-

dis

trac

tio

nte

chniq

ue,

div

ersi

fied

tech

niq

ue)

,cu

pp

ing

ther

apy

Mea

sure

imp

rovem

ent

rate

by

VA

San

dL

BP

asse

ssm

ent

qu

esti

on

nai

re

Both

dis

cog

enic

gro

up

and

sim

ple

bac

kp

ain

gro

up

wer

eim

pro

ved

by

chu

na

Tx

N/S

;P<

0.0

5

ME

NS

,m

icro

curr

ent

elec

tric

aln

euro

mu

scu

lar

stim

ula

tio

n;

OD

I,O

swes

try

dis

abil

ity

index

;H

A,

her

bal

acu

pu

nct

ure

;L

BP

,L

ow

bac

kp

ain

;IF

C,

inte

rfer

enci

alcu

rren

t;F

ES

,fu

nct

ion

alel

ectr

ical

stim

ula

tio

n.

eCAM 2005;2(3) 333

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Table

6.

Acu

pu

nct

ure

for

kn

eejo

int

pai

n

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

un

ctu

reL

eng

than

dn

um

ber

of

Tx

Oth

ertr

eatm

ents

Ass

essm

ent

Res

ult

so

fac

up

unct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

Ko

han

dK

ang

(56

)O

Ao

fk

nee

join

t5

0C

A(0

.25·

40

mm

),m

ox

ibu

stio

n1

5–

20

min

1/1

–2

day

sv

ario

us

tim

esH

erb

-med

Cla

ssif

ied

into

thre

eg

rou

ps

(exce

llen

t,g

oo

dan

dn

oim

pro

vem

ent)

by

clin

ical

eval

uat

ion

Ex

cell

ent,

28

.2%

;g

oo

d,

46

.2%

;n

oim

pro

vem

ent,

25

.6%

N/A

Lee

and

Seo

ng

(55

)O

Ao

fk

nee

join

t4

0C

A(1

0–

30

mm

)an

dfi

ren

eed

le,

indir

ect

mox

ibu

stio

n

15

min

dai

lyv

ario

us

tim

esD

rug

sfo

rex

tern

alap

pli

cati

on

,H

erb

-med

,ex

erci

se

Cla

ssif

ied

into

fou

rg

rou

ps

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

Mar

tin

A.N

.m

eth

od

Ex

cell

ent,

70

%;

go

od

,1

5%

;fa

ir,

10

%;

po

or,

5%

N/A

Na

and

Ah

n(5

7)

OA

of

kn

eejo

int

47

CA

(0.3

·3

0m

m),

mox

ibu

stio

nN

ot

stat

edC

up

pin

gth

erap

y(A

-shi

po

ints

),H

erb

-med

and

ho

tp

ack

,IF

C,

US

,T

DP

Cla

ssif

ied

into

fou

rg

rou

ps

(exce

llen

t,g

oo

d,

slig

ht

go

od

and

po

or)

by

asse

ssm

ent

of

Tx

(Am

eric

anR

heu

mat

ism

Ass

oci

atio

n)

Ex

cell

ent,

12

.8%

;g

oo

d,

48

.9%

;sl

igh

tg

oo

d,

27

.7%

;p

oo

r,1

0.6

%

N/A

Wo

oet

al.

(58)

Mic

rotr

aum

atic

inju

ries

of

the

kn

eejo

int

15

Do

ng

-si

acu

pu

nct

ure

(0.3

·3

0m

m,

0.2

15

mm

)

15

–30

min

3/1

wee

kfo

r3

wee

ks

Ex

erci

se(d

uri

ng

acup

un

ctu

reth

erap

y)

Mea

sure

thro

ug

hsc

ale

of

Cin

cin

nat

ik

nee

rati

ng

syst

em

Th

em

ean

nu

mb

ero

fb

efo

reT

xw

as6

0.6

and

afte

rw

as6

6.5

.A

tota

lo

f6

6.6

%o

fp

atie

nts

wer

eim

pro

ved

N/A

Wan

get

al.

(59

)O

Ao

fk

nee

join

t7

0B

V(4

00

0:1

,0

.1–0

.2m

l/1

acup

un

ctu

rep

oin

t)

1–

2/1

wee

kv

ario

us

tim

esN

on

eC

lass

ifie

din

tofi

ve

gro

ups

(exce

llen

t,g

oo

d,

fair

,p

oo

ran

db

ad)

by

kn

eejo

int

eval

uat

ion

scal

e(L

ysh

olm

and

Kar

lsso

n)

BV

Tm

ayp

lay

aro

lein

the

sig

nif

ican

tu

sefu

lnes

sag

ain

stO

Ap

atie

nts

P<

0.0

5

Kim

and

Lee

(60

)O

Ao

fk

nee

join

t6

04

02

0B

V(5

00

0:1

)C

A(0

.25·

30

mm

)2

/1w

eek

15

tim

es2

0m

ind

aily

var

ious

tim

es

No

ne

Cla

ssif

ied

into

fou

rg

rou

ps

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

chan

ges

of

sym

pto

ms

and

DIT

I

BV

Tg

rou

pw

ere

mo

reef

fect

ive

than

CA

gro

up

P<

0.0

1

Hw

ang

(62

)R

A1

8H

A(0

.1cc

/1ac

up

un

ctu

rep

oin

t),

mox

ibu

stio

n

1/2

–3

day

sv

ario

us

tim

esC

up

pin

gth

erap

y(1

/2–

3d

ays)

Cla

ssif

ied

into

fou

rg

rou

ps

(exce

llen

t,g

oo

d,

mo

der

ate,

po

or)

by

crit

eria

of

Am

eric

anR

heu

mat

ism

Ass

oci

atio

n

Ex

cell

ent,

6%

;g

oo

d,

6%

;m

od

erat

e,3

%;

po

or,

3

N/A

Hw

anget

al.

(61

)R

A1

5B

V(0

.1–

0.2

cc/1

acup

un

ctu

rep

oin

t)2

/1w

eek

var

ious

tim

esN

on

eM

easu

reC

RP

,E

SR

,R

Afa

cto

r,im

pro

vem

ent

index

and

clas

sifi

edin

tofo

ur

gro

ups

(exce

llen

t,good,

mod

erat

ean

dp

oo

r)b

ycl

inic

alev

aluat

ion

Ex

cell

ent,

40

%;

go

od,

46

.70

%;

mo

der

ate,

13

.30

%;

po

or,

0%

N/A

BV

,b

eev

eno

m;

BV

T,

bee

ven

om

ther

apy;

RA

,rh

eum

ato

idar

thri

tis;

CR

P,

C-r

eact

ive

pro

tein

;E

SR

,er

yth

rocy

tese

dim

enta

tio

nra

te;

OA

,O

steo

arth

riti

s;T

DP

,T

end

ing

Dia

nci

bo

Pu

.

334 Acupuncture in Korea

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Table

7.

Acu

pu

nct

ure

for

oth

erp

ainfu

ld

isea

ses

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

un

ctu

reL

eng

than

dn

um

ber

of

Tx

Oth

ertr

eatm

ents

Ass

essm

ent

Res

ult

so

fac

up

unct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

Cho

ian

dL

ee(6

9)

Acu

teg

ou

t2

1C

A(0

.2·

30

mm

)1

5m

ind

aily

var

iou

sti

mes

None

Cla

ssif

ied

into

four

gro

ups

(exce

llen

t,good,

slig

ht

and

un

chan

ged

)b

ycl

inic

alev

aluat

ion

Ex

cell

ent,

75

%;

go

od,

25

%;

slig

ht,

0%

;u

nch

ang

ed,

0%

N/A

Ban

get

al.

(67

)T

enn

isel

bo

w3

6C

A(0

.3·

50

mm

),m

ox

ibu

stio

n(A

-sh

ip

oin

ts,

3p

iece

/1w

eek

)

15

min

1/1

–3

day

sv

ario

us

tim

esU

S,

TE

NS

,fi

xat

ion

(ela

stic

ban

d)

Cla

ssif

ied

into

four

gro

ups

(exce

llen

t,good,

fair

and

po

or)

by

clin

ical

eval

uat

ion

Ex

cell

ent,

14

.1%

;g

oo

d,

52

.8%

;fa

ir,

21

%;

po

or,

10

.5%

N/A

Seu

ng

and

Ah

n(6

8)

Art

hri

tis

65

Dir

ect

moxib

ust

ion

1/2

day

s3

tim

esN

one

The

imm

une

acti

vit

ies

of

cell

(LT

T,

E-R

FC

)an

dim

mu

ne

acti

vit

yo

fli

gu

id(I

gG

,Ig

A,

IgM

,C

5)

wer

eo

bse

rved

.

Th

em

ox

ibu

stio

nsh

ow

edg

oo

def

fect

on

the

imm

un

eac

tiv

ity

inth

eh

um

anb

od

y

Var

iou

sP

-val

ues

Mu

ltin

euri

tis

22

Ind

irec

tm

ox

ibu

stio

n(w

ith

cutt

ing

slic

eo

ffr

esh

gin

ger

or

gar

lic

bu

lb)

2/1

wee

kT

he

imm

une

acti

vit

ies

of

cell

(3H

Td

R)

wer

eo

bse

rved

Cho

ian

dM

oo

n(6

5)

Pai

n(v

ario

us)

17

4D

eple

tion

of

blo

od

(th

ree-

edg

edn

eed

le,

vac

uum

extr

acto

r,A

-shi

po

ints

,to

tall

y5

–2

0m

l)

No

tst

ated

Not

stat

edC

lass

ifie

din

tofo

ur

gro

ups

(exce

llen

t,good,

unch

anged

and

bad

)b

ycl

inic

alev

alu

-at

ion

Ex

cell

ent,

20

.12

%;

go

od

,6

1.4

9%

;u

nch

ang

ed,

17

.24

%;

bad

,1

.15

%

N/A

Sh

imet

al.

(63

)P

ain

21

0E

A(0

.2·

50

mm

,0

.3·

65

mm

,1

2R

EP

Pb

yu

sin

gN

euro

R-7

0,

3–

10

Hz,

50

–15

0p

plo

wfr

equen

cy,

etc.

)

15

–30

min

1–

3/d

ay1

0ti

mes

Not

stat

edC

lass

ifie

din

tofo

ur

gro

ups

(mar

ked

imp

rovem

ent,

imp

rove,

tran

sien

tim

pro

vem

ent,

fail

)b

ych

anges

of

inves

tigat

ion

deg

ree

usi

ng

Neu

roR

-70

Mar

ked

imp

rovem

ent,

43

.3%

;im

pro

ve,

41

.4%

;tr

ansi

ent

imp

rovem

ent,

13

.8%

;fa

il,

1.5

%

N/A

Kim

etal.

(66

)A

nk

lesp

rain

26

13

13

CA

(0.3

·4

0m

m)

Tri

gg

erp

oin

tT

x

20

–30

min

var

iou

sti

mes

Var

iou

sti

mes

Ice

and

ho

tp

ack

,in

frar

edC

lass

ifie

din

tofo

ur

gro

ups

(exce

llen

t,good,

fair

and

po

or)

by

clin

ical

eval

uat

ion

Tri

gg

erp

oin

tT

xg

rou

pis

more

effe

ctiv

eth

anC

Ag

rou

p

N/A

Choet

al.

(64

)P

ost

tho

raco

tom

yp

ain

20

10

10

CA

(0.2

30

mm

),in

trad

erm

aln

eed

le(1

/2d

ays)

No

ne

20

–30

min

No

ne

An

alges

icre

qu

irem

ents

Mea

sure

sco

ring

syst

emfo

rp

ost

op

erat

ive

pai

nan

dth

en

um

ber

of

anal

ges

icre

qu

irem

ent

Th

en

um

ber

of

anal

ges

icre

qu

irem

ent

was

redu

ced

inth

eac

up

un

ctu

reg

rou

p

P<

0.0

5

Ah

net

al.

(70

)A

nk

lesp

rain

21

11

10

CA

(0.3

·3

0m

min

the

pai

nfu

lsi

de)

CA

(0.3

·3

0m

min

the

no

rmal

sid

e)N

on

e

5m

in

5m

in

No

ne

No

ne

Mea

sure

the

amper

age

from

12

left

and

rig

ht

Cho

ng

po

ints

Bet

wee

nth

eco

ntr

ol

and

the

ank

lesp

rain

gro

up,

ther

ew

ere

sig

nif

ican

td

iffe

ren

ces

bet

wee

nth

eam

per

ages

.T

he

acu

pu

nct

ure

toac

up

unct

ure

po

ints

inth

ep

ainfu

lsi

de

was

no

tle

ssef

fect

ive

than

the

acu

pu

nct

ure

toac

up

unct

ure

po

ints

N/A

RE

PP

,re

acti

ve

elec

tro

per

mea

bil

ity

po

int;

ES

T,

elec

tric

alst

imu

lati

on

ther

apy;

HN

P,

her

nia

ted

nu

cleu

sp

ulp

osu

s;S

SP

,si

lver

spik

ep

oin

t.

eCAM 2005;2(3) 335

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Kang et al. compared a group treated by Oriental-Western

treatment with a group treated by Oriental medical therapy

by evaluating House–Brackmeann grading system and made

a detailed evaluation of facial symmetry of Pillsbury and Fisch

(88,89). Kim et al. (89) compared a group treated by both acu-

puncture and herbal medicine with a group treated by acupunc-

ture in patients of facial nerve paralysis and demonstrated that

the symptoms were improved in both groups. Kwon et al. (90)

compared a group treated by conventional Oriental medicine

therapy with a group treated by conventional Oriental medi-

cine therapy and indirect moxibustion at ST4 and ST8 in peri-

pheral facial paralysis patients (Table 10).

Acupuncture for Other Conditions

Eye Disease (Opthalopathy)

Acupuncture and venesection were useful in treating 22

patients who suffered from acute infectious conjunctivitis

(91). Kim and Chae (92) reported 32 patients with cataract

or glaucoma who were treated by Oriental medicine and acu-

puncture. The therapeutic effect of acupuncture and moxibus-

tion on the sight of near-sighted patients was also reported

(93,94). Clinical studies were carried out to demonstrate the

effect of Oriental medicine and acupuncture on amblyopia

(95) (Table 11).

Nose Disease (Rhinopathy)

Acupuncture was effective in the treatment of allergic rhinitis

in 30 patients (96). Nasal acupuncture therapy was investig-

ated to treat the chronic paranasal sinusitis and nasal obstruc-

tion (97,98) (Table 12).

Ear Disease (Otopathy)

Clinical studies were carried out to investigate acupuncture,

moxibustion and venesection for tinnitus (99,100). It was

reported that acupuncture at TE5, GI41, TE6 SI5, GI38, KI2

and venesection improved symptoms of patients with otitis

media with effusion (101) (Table 13).

Figure 2. An excerpt from ‘The Simplified Diagram of Mingtang’ published in the Ming Dynasty. ‘Mingtang’ means mansion-house or hall and acupoints are

called ‘the house of Qi’. This may be another correlating factor between ‘acupoint’ and ‘Mingtang’. Since ‘Mingtang’ gradually became a substitute for ‘acupoint’,

the so-called ‘Mingtang diagram’ generally referred to ‘the diagram of acupoints’. (Courtesy of Dr Kim Nam-Il, Department of Medical History, College of

Oriental Medicine, Kyung Hee University, Seoul, South Korea.)

336 Acupuncture in Korea

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Table

8.

Acu

pu

nct

ure

for

stro

ke

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

unct

ure

Len

gth

and

nu

mb

ero

fT

xO

ther

trea

tmen

tsA

sses

smen

tR

esu

lts

of

acu

pu

nct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

Par

ket

al.

(73

)Is

chem

icst

roke

23

EA

(in

term

itte

nt)

15

min

on

ceN

on

eM

easu

reB

P,

PR

and

CB

F(b

yT

CD

)(b

efo

reac

up

un

ctu

re,

5,

10

and

15

min

afte

rac

up

unct

ure

)

EA

atG

V2

6-C

V2

4w

asef

fect

ive

on

incr

easi

ng

BP

,P

Ran

dC

BF

P<

0.0

5

Ah

net

al.

(74

)S

tro

ke

(hy

per

ten

sio

n)

22

AA

Fo

r2

4h

No

ne

Mea

sure

BP

(ev

ery

1–

2h

)A

Aw

asef

fect

ive

on

dec

reas

ing

BP

P<

0.0

5

Mo

onet

al.

(76

)Is

chem

icst

roke

28

13

15

EA

(0.2

40

mm

op

po

sing

nee

dli

ng

50

Hz

inte

rmit

ten

t)E

A(0

.25·

40

mm

ipsi

late

ral-

nee

dli

ng

50

Hz

inte

rmit

ten

t)

15

min

on

ce

Sam

e

No

ne

Mea

sure

Vm

,V

s,P

I(3

tim

es)

by

TC

DO

pp

osi

ng

nee

dli

ng

incr

ease

dce

rebra

lac

tiv

ity

mo

reth

anip

sila

tera

l-n

eed

ling

(Vs)

P<

0.0

5

Kan

get

al.

(75

)S

tro

ke

(hy

per

ten

sio

n)

30

15

15

CA

(0.2

30

mm

twir

lin

g5

–1

0s)

CA

(0.2

30

mm

sham

acu

pu

nct

ure

twir

lin

g5

–1

0s)

No

tst

ated

on

ce

Sam

e

No

ne

No

ne

Ch

eck

BP

13

tim

es(5

min

for

15

min

,1

5m

info

r4

5m

in,

30

min

for

2h

)

Acu

pu

nct

ure

Tx

atL

I11

,S

T3

6w

asu

sefu

lto

con

tro

lte

mp

ora

ryh

yp

erte

nsi

on

wit

hac

ute

stro

ke

(esp

ecia

lly

syst

oli

cB

P,

fro

m5

to1

50

min

inte

rval

afte

rac

up

unct

ure

Tx

)

P<

0.0

5

Lee

etal.

(72

)S

tro

ke

79

62

17

HT

NG

:v

enes

ecti

on

(Sy

psu

n-p

oin

ts1

–2

cc)

No

rmal

G:

sam

e

On

ce

Sam

e

Ch

eck

BP

and

BT

twic

eb

efo

reac

up

un

ctu

reT

xan

d3

tim

esaf

ter

acu

pu

nct

ure

Tx

(ev

ery

30

min

),u

nd

ergopost

hoc

Sch

effe

ind

exo

fG

LM

-rep

eate

dm

easu

red

def

ine

fact

ors

Ven

esec

tio

nat

Sypsu

n-p

oin

tsdec

reas

edB

P(c

ase

of

sev

ere

deg

ree)

P<

0.0

5

Haet

al.

(71

)S

tro

ke

29

14

CA

(0.3

·4

0m

m),

scal

pac

up

unct

ure

(co

ntr

alat

eral

10

–15

min

,tw

irli

ng

1–

3m

in),

mo

xib

ust

ion

15

–20

min

dai

lyv

ario

us

tim

esH

erb

-med

,cu

pp

ing

ther

apy,

ES

T,

etc.

(so

me

case

s)

Cla

ssif

ied

into

fou

rg

rou

ps

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

clin

ical

eval

uat

ion

CA

and

scal

pac

up

un

ctu

reg

rou

psh

ow

edal

mo

stsa

me

effe

ctco

mp

ared

wit

hC

Ag

rou

p

N/S

15

CA

(0.3

·4

0m

m),

mo

xib

ust

ion

Sam

e

CB

F,

cere

bra

lblo

od

flow

;T

CD

,tr

ansc

rania

ldopple

rso

nogra

phy;V

m,

mea

nb

loo

dfl

ow

vel

oci

ty;V

s,sy

sto

lic

blo

od

flo

wv

elo

city

;P

I,p

uls

atil

ity

ind

ex.

eCAM 2005;2(3) 337

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Table

9.

Acu

pu

nct

ure

for

po

stst

rok

ed

isea

ses

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

unct

ure

Len

gth

and

nu

mb

ero

fT

xO

ther

Tre

atm

ents

Ass

essm

ent

Res

ult

of

acu

pu

nct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

So

nget

al.

(77

)P

ost

stro

ke

hem

iple

gic

sho

uld

erjo

int,

sub

lux

atio

nan

dp

ain

38

EA

(0.2

40

mm

,8

po

ints

:o

rig

inan

din

sert

ion

site

of

sup

rasu

pin

atu

s,in

fras

pin

atus,

del

toid

m.

4H

zin

term

itte

nt)

,C

Aan

dm

ox

ibu

stio

n

15

min

dai

lyfo

r4

wee

ks

Sh

ou

lder

exer

cise

(15

min

,3

/1d

ay),

ph

ysi

cal

ther

apy

Mea

sure

RO

M,

VD

and

JDb

yX

-ray

,u

nd

ergo

mu

scle

po

wer

eval

uat

ion

(by

AM

A)

EA

was

effe

ctiv

eo

ntr

eati

ng

sho

uld

erjo

int,

sub

lux

atio

nan

dp

ain

afte

rst

rok

e

RO

M,P<

0.0

01

;V

D,P<

0.0

5;

JD,P<

0.0

1

Lee

and

Lee

(80

)S

ho

uld

erh

and

syn

d.

afte

rst

roke

23

11

12

EA

(0.2

40

mm

at5

Hz

mix

ed)

CA

(0.2

40

mm

)2

0m

in

20

min

dai

lyfo

r3

wee

ks

20

min

dai

lyfo

r3

wee

ks

No

ne

Mea

sure

DIT

I,R

OM

EA

gro

up

wer

em

ore

imp

roved

on

the

tem

per

atu

red

iffe

ren

ceo

fb

oth

do

rsal

han

ds

than

CA

gro

up

P<

0.0

1

23

No

ne

No

ne

Kan

gan

dB

aik

(79

)P

ost

stro

ke

sho

uld

erp

ain

12

09

03

0

30

30

CA

CA

CA

No

tst

ated

No

tst

ated

No

tst

ated

Ho

tp

ack

(20

min

dai

lyfo

r2

wee

ks)

,H

erb

-med

ICT

(10

0H

zco

nst

ant.

15

min

,d

aily

for

2w

eek

s),

Her

b-m

edT

EN

S(2

50

Hz,

15

min

dai

lyfo

r2

wee

ks)

Her

b-m

ed

Mea

sure

DIT

Ian

dR

OM

ICT

and

TE

NS

gro

up

wer

eef

fect

ive

on

trea

tmen

to

fp

ost

stro

ke

sho

uld

erp

ain

P<

0.0

5

30

CA

No

tst

ated

(Fo

r2

wee

ks)

Yin

etal.

(78

)P

ost

stro

ke

hem

iple

gic

sho

uld

erp

ain

24

12

15

BV

T(1

:10

00

0,

0.2

cc/1

acu

pu

nct

ure

po

int

3/w

eek),

CA

CA

Dai

ly(C

A)

for

4w

eeks

Sam

e

Her

b-m

ed,

exer

cise

,F

ES

Mea

sure

VA

S,

PR

OM

,F

ugel

–M

eyer

moto

ras

sess

men

t,m

odif

ied

Ash

wo

rth

scal

e

BV

Tg

rou

pw

asef

fect

ive

than

con

tro

lg

rou

po

nV

AS

,P

RO

M

P<

0.0

5

Kan

get

al.

(81

)P

ost

stro

ke

vo

idin

gd

ysf

unct

ion

20

10

10

Ind

irec

tm

ox

ibu

stio

n(5

pie

ce),

CA

CA

Dai

ly

No

tst

ated

Her

b-m

ed,

physi

cal

ther

apy,

etc

Ev

alu

ate

bal

ance

db

ladd

erti

me

and

resi

du

alu

rin

ev

olu

me

Mo

xib

ust

ion

was

effe

ctiv

eo

np

ost

stro

ke,

vo

idin

gd

ysf

unct

ion

N/S

VD

,v

erti

cal

dis

tan

ce;

JD,

join

td

ista

nce

;A

MA

,A

mer

ican

Med

ical

Ass

oci

atio

n;

PR

OM

,p

ain

less

pas

siv

eR

OM

of

sho

uld

erex

tern

alro

tati

on

.

338 Acupuncture in Korea

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Table

10.

Acu

pu

nct

ure

for

faci

alp

alsy

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

unct

ure

Len

gth

and

nu

mb

ero

fT

xO

ther

trea

tmen

tsA

sses

smen

tR

esult

so

fac

up

un

ctu

reth

erap

y

Sta

tist

ical

anal

ysi

s

Lee

and

Lee

(82

)P

erip

her

alfa

cial

par

aly

sis

72

CA

(0.3

30

mm

),D

on

g-s

hi

acu

pu

nct

ure

,E

A,

fire

nee

dle

20

min

var

ious

tim

esH

erb

-med

,S

SP

,ca

rbo

n(2

0m

in),

ES

T(2

0m

inat

3.5

Hz)

,in

frar

ed(2

0m

in3

–4

/1d

ay)

Cla

ssif

ied

into

fou

rg

rou

ps

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

clin

ical

eval

uat

ion

Ex

cell

ent,

55

.56

%;

go

od,

19

.44

%;

fair

,2

0.8

3%

;p

oo

r,4

.16%

N/A

Lee

(85

)P

erip

her

alfa

cial

par

aly

sis

85

CA

(0.2

30

mm

),E

A(1

–3

Hz

for

15

min

)

15

–20

min

1/2

–3

day

sv

ario

us

tim

es

Infr

ared

,W

este

rnm

edic

ine

(ste

roid

)C

lass

ifie

din

tofo

ur

gro

ups

(exce

llen

t,g

oo

d,

fair

-po

or

and

trac

e-ze

ro)

by

clin

ical

eval

uat

ion

Ex

cell

ent,

31

.76

%;

go

od,

32

.94

%;

fair

-po

or,

23

.53

%;

trac

e-ze

ro,

11

.77

%

N/A

So

nget

al.

(87

)B

ell’

sp

alsy

11

CA

(0.3

30

mm

)1

5–

20

min

var

iou

sti

mes

Infr

ared

,T

DP

Ex

amin

eD

ITI

(to

ok

pic

ture

�7

day

saf

ter

the

o/s

),cl

assi

fied

into

six

gro

ups

(no

rmal

,g

oo

d,

fair

,p

oo

r,tr

ace

and

zero

)b

yth

eg

rad

ing

syst

emo

ffa

cial

pal

sy

DIT

Iis

use

ful

for

pro

gno

stic

dia

gn

osi

so

fB

ell’

sp

alsy

(tem

per

atu

reo

fab

no

rmal

site"!

pro

gno

sis

isg

oo

d)

N/S

Ch

oet

al.

(86

)B

ell’

sp

alsy

16

CA

(0.2

30

mm

),fi

ren

eed

le2

0–

30

min

var

iou

sti

mes

Her

b-m

ed,

infr

ared

,C

arb

on

,T

EN

S,

ho

tp

ack

,et

c

Ex

amin

eD

ITI

(bef

ore

and

afte

rT

x)

and

clas

sifi

edin

tofo

ur

gro

ups

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

clin

ical

eval

uat

ion

DIT

Ish

ow

sth

erap

euti

cef

fect

of

acup

un

ctu

reT

x

N/A

Lee

and

Han

(83

)P

erip

her

alfa

cial

par

aly

sis

50

29

21

EA

(0.2

40

mm

,lo

ose

and

den

sew

ave

(til

lfi

rst

wee

k)

CA

(0.2

40

mm

)

15

–20

min

3H

zv

ario

us

tim

es

15

min

var

ious

tim

es

Infr

ared

,ca

rbo

n(2

0m

in),

faci

alm

assa

ge

and

exer

cise

Cla

ssif

ied

into

fiv

eg

rou

ps

(no

rmal

,ex

cell

ent,

go

od,

fair

and

po

or)

by

clin

ical

eval

uat

ion

EA

had

ab

ette

ref

fect

than

CA

N/A

Kan

get

al.

(88

)P

erip

her

alfa

cial

par

aly

sis

72

54

CA

(0.2

40

or

0.3

·5

0m

m),

EA

(fre

quen

cy3·

10

or

10

con

stan

t1

5m

in)

20

–30

min

var

iou

sti

mes

Infr

ared

,h

ot

pac

k,

faci

alm

assa

ge

(so

me

case

s)

Cla

ssif

ied

into

fou

rg

rou

ps

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

clin

ical

eval

uat

ion

Ex

cell

ent,

31

.5%

;g

oo

d,

37

%;

fair

,1

3%

;p

oo

r,1

8.5

%

N/A

18

Sam

eS

ame

Sam

ean

dp

red

nis

olo

ne

(for

10

day

s)E

xce

llen

t,1

1.1

%;

go

od,

55

.6%

;fa

ir,

33

.3%

;p

oo

r,0

%

Yu

net

al.

(84

)B

ell’

sp

alsy

16

8 8

HA

(Hom

inis

pla

centa

0.1

–0

.2cc

for

3d

ays)

,C

A(0

.25·

30

mm

)C

A(0

.25·

30

mm

)

15

–20

min

1/1

–2

day

sv

ario

us

tim

esH

erb

-med

,S

SP

,m

icro

wav

eo

rT

DP

,IC

T

Cla

ssif

ied

into

fou

rg

rou

ps

(exce

llen

t,g

oo

d,

fair

and

po

or)

by

Mu

scle

test

ing

(Lu

cill

eD

anie

ls)

Ex

cell

ent,

7;

go

od,

1E

xce

llen

t,4

;g

oo

d,

2;

fair

,0

;p

oo

r,2

N/A

eCAM 2005;2(3) 339

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Skin Disease (Dermatology)

It was reported that acupuncture and herbal medicine were

effective in the treatment of acne in 125 patients (102). It was

also found that acupuncture and herbal medicine improved the

symptoms of the acne patients (103) (Table 14).

Hypertension

Clinical studies with auricular acupuncture were performed on

23 patients with hypertension (104). Lee et al. (105) examined

moxibustion at LI11 and CV4 for blood pressure of hyper-

tension patients (Table 15).

Smoking and Drinking Cessation

Auricular acupuncture to stop smoking (106–110). Kim et al.

investigated the effect of auricular acupuncture on cessation

of drinking in alcoholic patients (111,112). It was reported

that auricular acupuncture and herbal medicine were effective

for quitting drinking (113) (Table 16).

Obesity

Electric acupuncture decreased body weight, abdominal

length, size of waist and body mass index (114,115). Lee and

Kim (116) compared auricular acupuncture combined with

acupuncture with auricular acupuncture combined with herbal

medicine for the treating obesity by measuring body weight

and percentage of body fat (Table 17).

Nausea and Vomiting

Auricular acupuncture on sympathetic, stomach, shenmen and

occiput points for postoperative nausea and vomiting in 100

female patients undergoing transabdominal hysterectomy. It

was demonstrated that electric acupuncture at PC6 and PC7

was very effective in preventing nausea, retching and vomiting

(118) (Table 18).

Obstetrics and Gynecology

Electric stimulation at acupuncture points significantly shor-

tened the delivery time and attenuated the pain during delivery

(119). Moreover, endometrial curettage was successfully per-

formed on 31 female patients under acupuncture anesthesia

(120) (Table 19).

Others

Moxibustion could have an effect on peripheral circulation

(121). Ahn et al. (122) examined the temperature change of

external genitalia in patients with impotence after herbal

medicine and acupuncture treatment. Auricular acupuncture

altered hormone and energy metabolism during weight control

of athletes (123) (Table 20).Table

10.Continued

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

un

ctu

reL

eng

than

dn

um

ber

of

Tx

Oth

ertr

eatm

ents

Ass

essm

ent

Res

ult

so

fac

up

un

ctu

reth

erap

y

Sta

tist

ical

anal

ysi

s

Kw

onet

al.

(90

)P

erip

her

alfa

cial

par

aly

sis

30

14

CA

(0.3

30

–5

0m

m),

join

edp

un

ctu

re,

EA

(som

eca

ses.

freq

uen

cy3·

10

or

10

,1

5m

in)

15

–2

0m

in2

–3

/1d

ayv

ario

us

tim

esIn

dir

ect

mo

xib

ust

ion

(1–

2/1

day

),H

erb-m

ed,

Wes

tern

med

icin

ein

frar

ed,

ho

tp

ack

,fa

cial

mas

sag

e,et

c

Cla

ssif

ied

into

fou

rg

rou

ps

(ex

cell

ent,

go

od,

fair

and

po

or)

by

clin

ical

eval

uat

ion

Ex

cell

ent,

21

.4%

;g

oo

d,

50

%;

fair

,2

1.4

%;

po

or,

7.2

%

N/A

16

Sam

eH

erb

-med

,W

este

rnm

edic

ine

infr

ared

,h

ot

pac

k,

faci

alm

assa

ge,

etc

Ex

cell

ent,

12

.5%

;g

oo

d,

31

.3%

;fa

ir,

31

.3%

;p

oo

r,2

5%

Kim

etal.

(89

)P

erip

her

alfa

cial

par

aly

sis

46

31

CA

(0.2

40

mm

0.3

·4

0m

m),

EA

(fre

qu

ency

10

or

10

),d

eple

tio

no

fb

loo

d(s

om

eca

ses)

15

–2

0m

in1

/1–

3d

ays

aver

age

16

.6ti

mes

Her

b-m

ed,

infr

ared

,T

DP

,fa

cial

mas

sag

eC

lass

ifie

din

tofo

ur

gro

up

s(e

xce

llen

t,g

oo

d,

fair

and

po

or)

by

clin

ical

eval

uat

ion

Ex

cell

ent,

36

%;

go

od,

39

%;

fair

,1

9%

;p

oo

r,6

%

N/A

15

Sam

eS

ame

aver

age

16.4

tim

esIn

frar

ed,

TD

P,

faci

alm

assa

ge

Exce

llen

t,33%

;g

oo

d,

47

%;

fair

,1

3%

;p

oo

r,7

%

340 Acupuncture in Korea

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Table

11.

Acu

pu

nct

ure

for

eye

dis

ease

(op

thal

mo

pat

hy)

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

unct

ure

Len

gth

and

nu

mb

ero

fT

xO

ther

trea

tmen

tsA

sses

smen

tR

esult

so

fac

up

unct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

Sim

etal.

(91

)A

cute

infe

ctio

us

con

jun

ctiv

itis

22

Dep

leti

on

of

blo

od

,af

terw

ard

CA

15

min

var

ious

tim

esN

one

Cla

ssif

ied

into

four

gro

ups

(rec

ov

ered

,g

oo

d,

un

chan

ged

and

aggra

vat

ed)

by

clin

ical

eval

uat

ion

Rec

over

ed,

20

;g

oo

d,

2N

/A

Ch

ae(9

4)

Vis

ual

acuit

y7

4C

AN

ot

stat

edav

erag

e2

.25

tim

es/w

eek

Her

b-m

edN

ot

stat

edN

ot

stat

edN

/A

Kim

and

Ch

ae(9

2)

Gla

uco

ma

Cat

arac

t

Cau

sin

g-b

lin

dn

ess-

dis

ease

4(3

5(0

23

(16

32

CA

No

tst

ated

Her

b-m

edIn

trao

cula

rp

ress

ure

,cl

inic

alev

aluat

ion

Cli

nic

alev

alu

atio

nan

da

eye

sigh

tte

stC

lin

ical

eval

uat

ion

Intr

aocu

lar

pre

ssu

re#,

75

%;

imp

rov

ed,

75

%Im

pro

ved

,4

0%

;ac

uit

y",

20

%Im

pro

ved

,5

7%

;n

ot

chan

ged

,3

0%

P<

0.0

5

N/S

P<

0.0

5

Ch

oiet

al.

(93

)N

ear

sig

hte

dn

ess

25

Th

est

amp

acup

un

ctu

re,

CA

(0.2

30

mm

),A

A,

mo

xib

ust

ion

(2/m

onth

)

20

min

3/w

eek

No

ne

Mea

sure

the

imp

rovem

ent

rate

of

eye

sigh

tin

each

case

so

fw

eari

ng

gla

sses

or

no

t.C

lass

ifie

din

tofo

ur

gro

ups

(go

od,

fair

,p

oo

ran

dfa

il)

by

the

imp

rov

emen

td

egre

eo

fb

oth

eyes

Po

ints

no

tw

eari

ng

gla

sses

wer

em

ore

imp

rov

edth

anp

oin

tsw

eari

ng

gla

sses

Go

od

,4

4%

;fa

ir,

40

%;

po

or,

12

%;

fail

,4

%

P<

0.0

5

Kim

etal.

(95

)A

mbly

op

ia1

8T

he

stam

pac

up

un

ctu

re,

CA

(0.2

30

mm

),A

A2

0m

in3

/wee

kfo

r3

mon

ths

Her

b-m

edM

easu

reth

eim

pro

vem

ent

rate

of

eye

sigh

tin

each

case

so

fw

eari

ng

gla

sses

or

no

tan

du

nd

ergo

aney

esi

gh

tte

st(2

/mo

nth

3ti

mes

)

Acu

pu

nct

ure

was

effe

ctiv

ein

imp

rov

emen

to

fey

esi

gh

t.Im

pro

vem

ent

deg

ree

0.2",

33

%;

0.1

–0

.2,

50

%;

0.1#,

17

%

P<

0.0

5

eCAM 2005;2(3) 341

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Table

12.

Acu

pu

nct

ure

for

no

sed

isea

se(r

hin

op

athy

)

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

unct

ure

Len

gth

and

nu

mb

ero

fT

xO

ther

trea

tmen

tsA

sses

smen

tR

esu

lts

of

acu

pu

nct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

Kim

and

Par

k(9

6)

All

erg

icrh

init

is3

0C

A,

EA

(2H

z,in

ten

sity

2–

3)

20

min

2–

3/w

eek

aver

age

22

.8ti

mes

Her

b-m

edC

linic

alev

aluat

ion

Fre

quen

cyof

trea

tmen

t"!

imp

rovem

ent"

N/A

Kim

and

Yo

on

(98

)N

asal

ob

stru

ctio

n3

2N

asal

acu

pu

nct

ure

(10·

14

0m

m)

15

min

2–

3/w

eek

Infr

ared

Cla

ssif

ied

into

thre

eg

rad

esb

yan

t.rh

ino

sco

py,

afte

rwar

dcl

assi

fied

into

fou

rg

rou

ps

(ex

cell

ent,

go

od,

un

chan

ge

and

wo

rse)

by

eval

uat

edg

rad

es

Ex

cell

ent,

31

.3%

;g

oo

d,

53

.1%

;u

nch

ang

e,9

.4%

;w

ors

e,6

.2%

N/A

Seo

and

Lee

(97

)E

mp

yem

a1

9N

asal

acu

pu

nct

ure

(0.3

75·

16

0m

man

do

bli

que

acup

un

ctu

rein

too

rifi

ceo

fS

inu

sm

axil

lari

s)

15

min

dai

lyav

erag

e1

1ti

mes

Infr

ared

Cla

ssif

ied

into

thre

eg

rou

ps

(ex

cell

ent,

go

od

and

un

chan

ged

)b

ycl

inic

alev

alu

atio

n,

rhin

isco

py

and

X-r

ay

Ex

cell

ent,

4;

go

od,

13

;u

nch

ang

ed,

2N

/A

Table

13.

Acu

pu

nct

ure

for

ear

dis

ease

(oto

pat

hy

)

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

unct

ure

Len

gth

and

nu

mb

ero

fT

xO

ther

trea

tmen

tsA

sses

smen

tR

esult

so

fac

up

unct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

Par

ket

al.

(99

)T

inn

itu

s3

0C

A1

/2–

3d

ays

Infr

a,cu

pp

ing

ther

apy

,la

ser

ther

apy,

mo

xib

ust

ion,

Her

b-m

ed

Sco

re(0

–7

)b

yq

ues

tio

nn

aire

,m

easu

resu

cces

sra

tean

dre

cov

ery

rate

Succ

ess

rate

,76.6

%;

reco

ver

yra

te,

42

.2%

N/A

Kim

(10

0)

Tin

nit

us

47

CA

No

tst

ated

Cu

pp

ing

ther

apy,

mo

xib

ust

ion,

Her

b-m

edC

lass

ifie

din

tofo

ur

gro

ups

(co

mple

tere

cov

ered

,si

gn

ific

ant,

go

od

and

un

chan

ged

)b

ych

ang

eso

fsy

mp

tom

Tin

nit

us

incl

ud

edin

oth

ersy

mp

tom

san

dac

com

pan

ied

by

ver

tigo

ver

tig

o!

trea

tmen

tef

fici

ency"

N/A

Lee

etal.

(10

1)

Oti

tis

med

iaw

ith

effu

sion

18

Dep

leti

on

of

blo

od

,C

A(0

.20·

30

mm

)

15

min

(sti

mula

tio

n2

tim

es)

aver

age

14

.5ti

mes

No

ne

Cla

ssif

ied

into

thre

eg

rou

ps

(ex

cell

ent,

go

od

and

un

chan

ged

)b

ycl

inic

alev

aluat

ion

and

oto

sco

py

Ex

cell

ence

,2

2.2

%;

go

od,

66

.7%

;u

nch

ang

ed,

11

.1%

N/A

342 Acupuncture in Korea

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Acupuncture for Human Study

Acupuncture stimulation significantly decreased electrical

resistance under the adiaphoresis, suggesting that the decrease

of electrical resistance is caused not only by sweat secretion

but also by other internal resistance (124). Youn et al. (125)

reported a strong correlation between acupuncture at KI6

and cortical activation in the motor-related region of the

human brain by using fMRI. Acupuncture at LI4 in the left

hand increased regional CBF (rCBF) in the right parietal

lobe, middle temporal gyrus and inferior occipital lobe, and

electric acupuncture at ST36 on the right side increased

rCBF in the left temporal lobe, the inferior frontal lobe

and cerebellar hemisphere using single photon emission

computed tomography (126,127). It was shown that acupunc-

ture at LI4 and LV3 could ipsilaterally enlarge a blind spot

map (128).

Several studies were performed to examine if acupuncture at

LI4 changed skin temperature in the LI4 area of the hand, LI11

area of the arm, LI20 area of the face and ST25 area of the

abdomen by using DITI (129–135). It was also examined to

see whether the alteration of acupuncture manipulation

method could change the temperature in these regions of the

body (136,137). Other studies were performed to investigate

the effects of acupuncture at LU9 by thermal change in the

five shu points or LU9 and LU1 areas of lung meridian

(138,139). Yook et al. (140) examined whether HA at BL12,

BL13, BL41 and BL42 could affect local thermal change by

using DITI. Kim et al. (141) examined whether acupuncture

at the WuHu acupoint could affect thermal change in the ankle

region (Table 21).

Discussion

A large number of clinical studies have used acupuncture;

electric acupuncture, moxibustion and other traditional therap-

ies to target a relatively broad range of medical problems,

primarily pain and stroke. Moreover, acupuncture has been

widely used for treatment of facial palsy, obesity, hyperten-

sion, nausea and vomiting, and many other diseases. However,

as mentioned in the beginning of this report, the studies had

various weaknesses such as inadequate sample size, inappro-

priate control treatment, inadequate follow-up, inadequate

control of non-specific effects, inadequate reporting of side

effects and a few studies’ failure to replicate results. These

concerns make it difficult to draw clear conclusions about effi-

cacy in most areas where acupuncture has been tested.

A number of systematic reviews on acupuncture for specific

conditions have recently been published, including an extens-

ive systematic review on chronic pain, with a far reaching

search strategy and a way of scoring trial methodology (142).

Recently, the best evidence synthesis review showed that there

was only limited evidence that acupuncture is more effective

than no treatment (waiting list) and inconclusive evidence

that acupuncture is more effective than inert placebo, sham

acupuncture or standard medical care (143). In addition, theTable

14.

Acu

pu

nct

ure

for

skin

dis

ease

(der

mat

op

ath

y)

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

unct

ure

Len

gth

and

nu

mb

ero

fT

xO

ther

trea

tmen

tsA

sses

smen

tR

esult

so

fac

up

unct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

Ch

ae(1

02

)A

cne

(Co

med

o)

12

5(1

17

)C

A2

0m

in2

–3

/1w

eek

aver

age

5.4

4ti

mes

Her

b-m

ed,

dru

gs

for

exte

rnal

app

lica

tio

nS

core

(1–

20)

by

Con

sen

sus

con

fere

nce

on

acn

ecl

assi

fica

tio

n

No

tst

ated

N/A

Kim

and

Kim

(10

3)

Acn

e(C

om

edo)

8(4

)M

etho

ds

of

rein

forc

emen

tan

dre

duct

ion,

AA

No

tst

ated

2/w

eek

(AA

)D

rug

sfo

rex

tern

alap

pli

cati

on

(med

icin

alp

ow

der

for

Co

med

o),

Her

b-m

ed

Cli

nic

alev

aluat

ion

No

ne

N/A

eCAM 2005;2(3) 343

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Table

16.

Acu

pu

nct

ure

for

smo

kin

gan

dd

rin

kin

gce

ssat

ion

Au

tho

rn

ame(

s)N

um

ber

of

po

ints

Ty

pe

of

acup

un

ctu

rean

dac

up

unct

ure

po

ints

Len

gth

and

nu

mb

ero

fT

xO

ther

trea

tmen

tsA

sses

smen

tR

esu

lto

fac

up

unct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

Lee

etal.

(11

0)

60

6C

A(0

.25·

40

mm

)af

terw

ard

,A

A(s

ame

po

ints

)

15

–20

min

2/w

eek

var

ious

tim

esN

on

eC

lass

ifie

din

tofi

ve

gro

ups

(rec

over

ed,

go

od,

mod

erat

e,sl

igh

tan

du

nch

ang

ed)

by

clin

ical

eval

uat

ion

Rec

over

ed,

40

.5%

;g

oo

d,

26

.7%

;m

od

erat

e,1

9.5

%;

slig

ht,

5.3

%;

un

chan

ged

,8

.1%

N/A

Ah

net

al.

(10

7)

10

7A

A2

/wee

kav

erag

e4

.07

tim

esN

on

ef/

u1

yea

raf

ter

Tx

,cl

assi

fied

into

fiv

eg

rou

ps

(rec

over

ed,

go

od,

mod

erat

e,sl

igh

tan

du

nch

ang

ed)

by

clin

ical

eval

uat

ion

Rec

over

ed,

22

.4%

;g

oo

d,

5.6

%;

mo

der

ate,

19

.6%

;sl

igh

t,1

6.8

%;

un

chan

ged

,3

5.5

%

N/A

Hw

anget

al.

(10

6)

20

3C

A(0

.3·

30

mm

)af

terw

ard

,A

A(s

ame

po

ints

)

20

min

2/w

eek

var

ious

tim

es

No

ne

Cla

ssif

ied

into

fiv

eg

rou

ps

(rec

over

ed,

go

od,

mod

erat

e,sl

igh

tan

du

nch

ang

ed)

by

clin

ical

eval

uat

ion

Rec

over

ed,

24

%;

go

od,

32

%;

mo

der

ate,

27

%;

slig

ht,

5%

;u

nch

ang

ed,

12

%

N/A

Ch

oi

(10

9)

37

AA

,C

A(c

on

tral

ater

alsi

de)

15

min

2/w

eek

aver

age

2.9

5ti

mes

No

ne

Cla

ssif

ied

into

fiv

eg

rou

ps

(rec

over

ed,

go

od,

mod

erat

e,sl

igh

tan

du

nch

ang

ed)

by

clin

ical

eval

uat

ion

Rec

over

ed,

43

.2%

;g

oo

d,

24

.3%

;m

od

erat

e,1

6.2

%;

slig

ht,

13

.5%

;u

nch

ang

ed,

2.7

%

N/A

Ch

oi

and

Hw

ang

(10

8)

43

92

49

19

0A

AS

ham

AA

2/w

eek

for

3w

eek

s2

/wee

kfo

r3

wee

ks

No

ne

Cla

ssif

ied

into

fiv

eg

rou

ps

by

clin

ical

eval

uat

ion

and

com

par

eB

etw

een

exer

cise

/contr

ol

no

sig

nif

ican

td

iffe

ren

ce,

but

AA

:ef

fect

ive

N/A

Kim

etal.

(11

1)

23

3C

A(0

.25·

40

mm

),A

A(s

ame

po

ints

,co

ntr

alat

eral

side)

15

–20

min

1/3

–4

day

sv

ario

us

tim

esN

on

eC

lass

ifie

din

tofi

ve

gro

ups

(rec

over

ed,

go

od,

mod

erat

e,sl

igh

tan

du

nch

ang

ed)

by

qu

it-d

rin

kin

gd

ura

tio

n

Th

esu

cces

sra

te,

74

.7%

;th

ere

cov

ered

rate

,4

3.8

%N

/A

Par

kan

dP

eun

(113)

50

CA

,af

terw

ard

AA

(bo

thsi

des

,sa

me

po

ints

)

20

min

2/w

eek

aver

age

7.3

6ti

mes

Her

b-m

edN

on

eN

on

eN

/A

Lee

etal.

(11

2)

13

3C

A,

AA

(sam

ep

oin

ts,

con

tral

ater

alsi

de)

15

–20

min

2/w

eek

for

5d

ays

Her

b-m

edC

lass

ifie

din

toth

ree

gro

ups

(go

od

,fa

iran

dn

ore

spo

nse

)b

ycl

inic

alev

alu

atio

nG

oo

d,

52

.7%

;fa

ir,

14

.5%

;n

ore

spo

nse

,3

2.8

%N

/A

Table

15.

Acu

pu

nct

ure

for

hy

per

ten

sio

n

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

unct

ure

Len

gth

and

nu

mb

ero

fT

xO

ther

trea

tmen

tsA

sses

smen

tR

esult

of

acup

un

ctu

reth

erap

yS

tati

stic

alan

aly

sis

Byun

and

Ahn

(104)

Hyper

tensi

on

23

AA

2/1

wee

kN

one

Cla

ssif

ied

into

five

gro

ups

by

aver

age

BP

(To

kyo

Un

iver

sity

)

AA

was

effe

ctiv

eon

trea

ting

hy

per

ten

sio

nN

/A

Lee

etal.

(105)

Hyper

tensi

on

25

Indir

ect

moxib

ust

ion

(3p

iece

)2

/1w

eek

10

tim

esN

on

eM

easu

reB

P6

tim

es(1

/1w

eek

)C

on

stan

tm

ox

ibu

stio

nat

LI1

1,

CV

4sh

ow

edd

ecre

ase

of

BP

P<

0.0

5

344 Acupuncture in Korea

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Table

18.

Acu

pu

nct

ure

for

nau

sea

and

vo

mit

ing

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

unct

ure

(exer

cise

gro

up)

Len

gth

and

nu

mb

ero

fT

x(e

xer

cise

gro

up)

Oth

ertr

eatm

ents

Ass

essm

ent

Res

ult

so

fac

up

unct

ure

ther

apy

Sta

tist

ical

anal

ysi

sT

yp

eo

fac

up

un

ctu

re(c

on

tro

lg

rou

p)

Len

gth

and

nu

mb

ero

fT

x(c

on

tro

lg

rou

p)

Kim

etal.

(118)

Post

oper

ativ

en

ause

aan

dv

om

itin

g

10

05

0

50

EA

(0.2

40

mm

PC

6P

C7

twir

lin

g3

Hz

inte

nsi

tyti

lln

ot

feel

ing

pai

n)

No

ne

15

min

No

ne

Var

ious

Tx

for

op.

Chec

kin

ciden

ceo

fn

ause

a,re

tch

ing

and

vo

mit

ing

bli

nd

lyev

ery

3h

afte

ro

p.

for

12

h

EA

gro

up

sho

wed

bet

ter

resu

lts

for

12

haf

ter

op

.(e

ver

y3

h)

P<

0.0

01

Kim

etal.

(117)

Post

oper

ativ

en

ause

aan

dv

om

itin

g

10

05

05

0A

AN

on

eN

ot

stat

edN

on

eV

ario

us

Tx

for

op.

Chec

kin

ciden

ceof

nau

sea,

retc

hin

gan

dv

om

itin

gb

lin

dly

ever

y3

haf

ter

op

.fo

r1

2h

AA

gro

up

sho

wed

bet

ter

resu

lts

for

12

haf

ter

op

.(e

ver

y3

h)

P<

0.0

1

Op.,

oper

atio

n.

Table

17.

Acu

pu

nct

ure

for

ob

esit

y

Au

tho

rn

ame(

s)N

um

ber

of

po

ints

Ty

pe

of

acu

pu

nct

ure

and

acup

un

ctu

rep

oin

tsL

eng

than

dn

um

ber

of

Tx

Oth

ertr

eatm

ents

Ass

essm

ent

Res

ult

of

acu

pu

nct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

Lee

and

Lee

(11

4)

72

EA

(lef

tan

dri

gh

tei

ght

acu

pu

nct

ure

po

ints

loca

ted

on

the

abd

om

en,

ho

rizo

nta

lm

eth

od

,2

00

–2

50

Hz)

40

min

aver

age

8.6

0ti

mes

None

Cla

ssif

ied

into

four

gro

ups

(go

od

,m

od

erat

e,sl

igh

tan

du

nch

ang

ed)

by

chan

ges

of

wei

gh

tan

dci

rcu

mfe

ren

ceo

fab

do

men

Go

od

,2

5%

;m

od

erat

e,3

1.9

%;

slig

ht,

31

.9%

;u

nch

ang

ed,

11

.2%

N/A

Jeo

nget

al.

(11

5)

9C

A(v

ario

us)

,E

A(n

ot

stat

ed),

AA

(var

ious)

No

tst

ated

aver

age

(EA

)1

2.9

tim

esV

ario

us

(die

t,ex

erci

se,

etc.

)M

easu

rew

eig

ht,

fat

mas

s,p

erce

nt

bo

dy

fat,

fat

dis

trib

uti

on,

rela

tiv

eb

od

yw

eig

ht,

BM

I

Wei

gh

t(k

g),

5.6

6#;

fat

mas

s(k

g),

3.2

8#;

per

cen

tb

od

yfa

t(%

),2

.83#;

fat

dis

trib

uti

on

,0

.05#;

rela

tiv

eb

od

yw

eig

ht

(%),

10

.4#;

BM

I,2

.2#;

circ

um

fere

nce

of

abd

om

en,

2.2

5#

N/A

Lee

and

Kim

(11

6)

16

8C

A,

AA

15

min

dai

lyF

or

7w

eek

s(3

wee

ks,

firs

tp

erio

d;

1w

eek

,re

st;

3w

eek

s,se

con

dp

erio

d)

Mea

sure

wei

ght,

per

cent

body

fat,

com

par

eex

erci

seg

rou

p.

wit

hco

ntr

ol

gro

up

and

firs

tp

erio

dw

ith

seco

nd

per

iod

AA

–C

Ag

rou

pw

asm

ore

effe

ctiv

eth

anA

A–H

erb-m

edg

rou

p

N/A

8A

A,

afte

rwar

dst

ick

Sin

apis

sem

en1

5m

in1

/3d

ays

BM

I,b

od

ym

ass

ind

ex.

eCAM 2005;2(3) 345

Page 22: The Practice of Korean Medicine: An Overview of Clinical ... · The Practice of Korean Medicine: An Overview of Clinical Trials in Acupuncture Yong-Suk Kim1, ... cupping therapy and

Table

19.

Acu

pu

nct

ure

for

ob

ster

ics

and

gy

nec

olo

gy

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

un

ctu

ren

um

ber

and

acu

pu

nct

ure

po

ints

Len

gth

and

nu

mb

ero

fT

xO

ther

trea

tmen

tsA

sses

smen

tR

esult

of

acu

pu

nct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

Kim

and

Kim

(12

0)

Acu

pu

nct

ure

anes

thes

ia(c

ure

ttag

e)

31

EA

(0.2

40

mm

1–

3.5

Hz

adju

stin

ten

sity

)

Du

ring

cure

ttag

eN

on

eC

lass

ifie

din

toth

ree

gro

up

s(e

xce

llen

t,g

oo

dan

dp

oo

r)b

yin

ject

ion

amo

un

to

fp

ento

thal

sod

ium

Ex

cell

ent,

22

;g

oo

d,

5;

po

or,

4N

/A

Kim

etal.

(11

9)

Lab

or

inp

rim

ipar

a3

91

2E

A(1

–3

Hz

con

stan

t,ad

just

inte

nsi

ty)

Fro

mac

tiv

ep

has

e(f

irst

stag

eo

fla

bo

r)to

ph

ase

of

pla

centa

lse

par

atio

n(t

hir

dst

age

of

lab

or)

on

ce

No

ne

Th

ed

ura

tio

no

fla

bo

ro

fex

erci

seg

rou

pw

assh

ort

erth

anth

ato

fco

ntr

ol

gro

up

Th

ed

ura

tio

no

fla

bo

ro

fex

erci

seg

rou

pw

assh

ort

erth

anth

ato

fco

ntr

ol

gro

up

P<

0.0

5

27

No

ne

No

ne

Table

20.

Acu

pu

nct

ure

for

oth

erco

nd

itio

ns

Au

tho

rn

ame(

s)C

on

dit

ion

trea

ted

Nu

mb

ero

fp

oin

tsT

yp

eo

fac

up

unct

ure

and

acu

pu

nct

ure

po

ints

Len

gth

and

nu

mb

ero

fT

xO

ther

trea

tmen

tsA

sses

smen

tR

esu

lto

fac

up

unct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

Hw

ang

and

Yan

g(1

21

)P

erip

her

alb

loo

dci

rcu

lati

on

dis

turb

ance

20

Ind

irec

tm

ox

ibu

stio

n(t

hre

ep

iece

)

On

ceN

on

eM

easu

rep

erip

her

alb

loo

dci

rcula

tion

usi

ng

asse

ssin

g22

gra

des

Th

ein

dir

ect

mo

xib

ust

ion

(10

-jo

ng

po

ints

)w

ere

use

ful

for

per

iph

eral

blo

od

circ

ula

tio

n

N/A

Ah

net

al.

(12

2)

Imp

ote

nce

12

Saa

mac

up

un

ctu

reN

ot

stat

ed1

/wee

kfo

r2

mo

nth

sH

erb

-med

Mea

sure

the

tem

per

atu

reu

sin

gD

ITI

Th

eth

erm

o-d

iffe

ren

ceo

fle

ftth

igh

and

gla

ns

pen

is,

bo

thsc

rota

incr

ease

dsi

gn

ific

antl

y

P<

0.0

5

Yo

uet

al.

(12

3)

Th

ech

ang

eo

fh

orm

on

ean

den

erg

ym

etab

oli

smd

uri

ng

wei

gh

tco

ntr

ol

of

Tae

kw

on

do

pla

yer

s

20

10

10

AA

No

ne

1/3

day

sfo

r2

wee

ks

No

ne

Lo

wca

lori

ed

iet,

sau

na

and

reg

ula

rex

erci

se,

etc.

An

alysi

sth

ele

vel

of

Naþ

,Kþ

,C

l�,

Caþ

þ,

crea

tinin

e,co

rtis

ol,

epin

eph

rine

and

no

rep

inep

hri

ne

AA

was

sho

wn

incr

ease

lev

els

of

Naþ

,co

rtis

ol,

epin

ephri

ne,

dec

reas

ele

vel

so

fle

pti

nth

atp

rod

uct

so

fo

b-g

ene

P<

0.0

5(N

aþ,

cort

iso

l,ep

inep

hri

ne)

P<

0.0

1(l

epti

n)

346 Acupuncture in Korea

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Table21.

Acu

pu

nct

ure

for

hu

man

stud

y

Au

tho

rn

ame(

s)N

um

ber

of

po

ints

Ty

pe

of

acu

pu

nct

ure

and

acup

un

ctu

rep

oin

ts

Len

gth

and

nu

mb

ero

fT

xA

sses

smen

tp

oin

tsM

easu

rem

om

ents

Res

ult

of

acupunct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

Lee

etal.

(12

9)

15

CA

(0.2

40

mm

rig

ht

LI4

twir

lin

g7

–8

tim

es)

30

min

LI4

LI1

1B

efo

reac

up

un

ctu

rest

imu

lati

on

,3

0s,

1m

in,

10

min

,3

0m

inaf

ter

acup

un

ctu

rest

imu

lati

on

and

10

min

afte

rn

eed

le-

rem

oval

DIT

Iis

au

sefu

lm

eth

od

too

bse

rve

and

f/u

the

effe

cts

and

the

chan

ges

by

acup

un

ctu

rest

imu

lati

on

for

obje

ctiv

eev

aluat

ion

N/A

Han

etal.

(13

1)

54

CA

(0.3

·3

0m

mle

ftL

I4)

15

min

LI2

0B

efo

reac

up

un

ctu

rest

imu

lati

on

,5

,1

0an

d1

5m

inaf

ter

acup

un

ctu

rest

imu

lati

on

Acu

pu

nct

ure

can

mo

du

late

the

equ

ilib

riu

mo

fU

m-Y

ang

and

Keo

-ja

theo

ry

Var

iou

sP

-val

ues

So

hnet

al.

(13

0)

95

73

CA

(0.2

30

mm

bo

tho

rri

gh

tL

I4)

10

min

LI4

ST

25

Bef

ore

acup

un

ctu

rest

imu

lati

on

,an

d1

,1

0m

inaf

ter

acup

un

ctu

rest

imu

lati

on

Acu

punct

ure

on

LI4

affe

cts

toth

erm

alch

ang

eso

fL

I4an

dS

T2

5

Var

iou

sP

-val

ues

22

No

ne

No

ne

So

nget

al.

(13

2)

42

27

CA

(0.2

30

mm

rig

ht

LI4

)1

0m

inL

I11

LI2

0B

efo

reac

up

un

ctu

rest

imu

lati

on

,an

d1

,1

0m

inaf

ter

acup

un

ctu

rest

imu

lati

on

Acu

punct

ure

on

LI4

affe

cts

toth

erm

alch

ang

eso

fL

I11

and

LI2

0

Var

iou

sP

-val

ue

15

No

ne

No

ne

So

nget

al.

(13

7)

60

20

CA

(0.3

·3

0m

mle

ftL

I4le

ft)

10

min

LI1

-5B

efo

reac

up

un

ctu

rest

imu

lati

on

,an

d1

0m

inaf

ter

acup

un

ctu

rest

imu

lati

on

On

ep

oin

tw

ith

the

left

or

rig

ht

rota

ryac

up

unct

ure

stre

ssef

fect

sth

eoth

erpoin

tsw

hic

hh

ave

rela

tio

nw

ith

it

Var

iou

sP

-val

ues

20

CA

(0.3

·3

0m

mle

ftL

I4ri

gh

t)1

0m

in

20

No

ne

No

ne

Hw

anget

al.

(13

4)

10

03

5C

A(0

.3·

30

mm

left

LI4

)1

0m

inL

I4S

T2

5C

V12

Bef

ore

acup

un

ctu

rest

imu

lati

on

,an

d5

,1

0m

inaf

ter

acup

un

ctu

rest

imu

lati

on

Acu

punct

ure

on

LI4

affe

cts

toth

erm

alch

ang

eso

fS

T2

5an

dC

V1

2(a

bd

om

inal

surf

ace)

Var

iou

sP

-val

ues

35

CA

(0.3

·3

0m

mb

oth

LI4

)1

0m

in

30

No

ne

No

ne

Yu

net

al.

(13

5)

30

10

No

ne

No

ne

GV

25

and

left

LI2

0ri

gh

tS

4an

dri

gh

tL

I20

left

S4

Bef

ore

acup

un

ctu

rest

imu

lati

on

,an

d3

,1

0,

15

,2

5an

d4

5m

inaf

ter

acup

un

ctu

rest

imu

lati

on

Th

esk

inte

mp

erat

ure

of

EA

gro

up

wer

em

ore

incr

ease

than

the

con

tro

lg

rou

p.

Th

ete

mp

erat

ure

of

H5

,7g

rou

pw

ere

more

incr

ease

than

the

LI3

,4

gro

up

Var

iou

sP

-val

ues

10

EA

(0.3

·3

0m

mri

gh

tL

I4L

I32

Hz

Hi-

CO

NT

.)

15

min

10

EA

(0.3

·3

0m

mri

gh

tH

7H

52

Hz

Hi-

CO

NT

.)

15

min

Kim

etal.

(13

9)

60

30

CA

(0.3

·3

0m

mL

9)

10

min

LU

9P

T7

LU

1C

V2

2B

efo

reac

up

un

ctu

rest

imu

lati

on

,an

d1

0m

inaf

ter

acup

un

ctu

rest

imu

lati

on

Th

eac

up

un

ctu

rest

imu

lati

on

on

L9

affe

cted

the

ther

mal

chan

ge

of

the

area

that

isa

mer

idia

np

oin

t,in

lung

mer

idia

n

Var

iou

sP

-val

ues

eCAM 2005;2(3) 347

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Table

21.Continued

Au

tho

rn

ame(

s)N

um

ber

of

po

ints

Ty

pe

of

acu

pu

nct

ure

and

acu

pu

nct

ure

po

ints

Len

gth

and

nu

mb

ero

fT

xA

sses

smen

tp

oin

tsM

easu

rem

om

ents

Res

ult

of

acu

pu

nct

ure

ther

apy

Sta

tist

ical

anal

ysi

s

30

No

ne

No

ne

Yo

oket

al.

(14

0)

23

23

22

N/S

(0.0

5cc

/1ac

up

un

ctu

rep

oin

t)

HA

(Car

tham

ise

men

0.0

5cc

/1ac

up

un

ctu

rep

oin

t)

No

ne

No

ne

BL

12

BL

13

BL

41

BL

42

Bef

ore

HA

,an

d1

,2

4,

48

h,

7d

ays

afte

rH

A

HA

fluid

has

dif

fere

nt

effe

cts

on

the

der

mat

oth

erm

alch

ang

efo

llo

win

gti

mes

.B

Ug

rou

pis

late

stin

du

rati

on

of

ph

ysi

cal

reac

tion

Var

iou

sP

-val

ues

23

HA

(Fel

Urs

Bez

oar

Bov

is.

0.0

5cc

/1ac

up

un

ctu

rep

oin

t)

No

ne

So

ng

and

Yo

ok

(13

8)

60

30

30

CA

(0.3

·3

0m

mle

ftL

9)

No

ne

10

min

No

ne

LU

8-L

U11,

LU

5(f

ive

shu

po

ints

)

Bef

ore

acu

pu

nct

ure

stim

ula

tio

n,

and

10

min

afte

rac

up

unct

ure

stim

ula

tio

n

Th

eac

up

un

ctu

reo

nL

9af

fect

edth

eth

erm

alch

ang

eo

fth

ear

eath

atw

asth

efi

ve

shu

po

ints

inth

elu

ng

mer

idia

n

Var

iou

sP

-val

ues

Kim

etal.

(14

1)

45

25

20

Do

ng

-shi

acu

pu

nct

ure

(0.3

·4

0m

mW

u-H

u)

No

ne

10

min

No

ne

BL

60

BL

62

GB

40

ST

41

Bef

ore

acu

pu

nct

ure

stim

ula

tio

n,

and

10

min

afte

rac

up

unct

ure

stim

ula

tio

n

Th

eac

up

un

ctu

reo

nth

eW

u-H

uw

asef

fect

ive

atth

ean

kle

regio

nV

ario

usP

-val

ues

Par

k(1

24

)1

5C

A(0

.25·

40

mm

Lt.

P8)

12

min

Mea

sure

the

elec

tric

alre

sist

ance

of

anes

thet

ized

left

P6

,an

esth

etiz

edn

on

-acu

pu

nct

ure

po

int,

no

rmal

left

P4

and

no

rmal

rig

ht

P6

Wh

enth

eac

up

unct

ure

stim

ula

tion

isap

pli

edto

hu

man

bo

dy,

the

dec

reas

eof

elec

tric

alre

sist

ance

isnot

only

tosw

eat

secr

etio

nb

ut

also

too

ther

inte

rnal

resi

stan

ce

P<

0.0

1(d

ryel

ectr

od

e)P<

0.0

5(w

etel

ectr

od

e)

Yo

unet

al.

(12

5)

5C

A(K

I6)

(Tw

ist

for

70

san

dre

stfo

r7

0s)

·3

Ex

amin

eB

OL

Dre

spo

nse

by

fMR

IA

cup

unct

ure

atK

I6re

sult

edin

neg

ativ

eB

OL

Dre

spo

nse

tost

imu

lati

on

No

tst

ated

Kim

etal.

(12

6)

11

5E

A(0

.3·

40

mm

ST

36

2H

zco

nst

ant)

20

min

Mea

sure

rCB

Fb

yre

st/E

AT

c-9

9m

EC

Db

rain

SP

EC

Tu

sin

ga

sam

e-do

sesu

btr

acti

on

met

ho

d

EA

atS

T3

6in

crea

sed

rCB

Fin

the

contr

alat

eral

cere

bra

lh

emis

ph

ere

P<

0.9

6S

ham

acup

un

ctu

re2

0m

in

Ohet

al.

(12

7)

11

5 6C

A(0

.3·

40

mm

left

LI4

)S

ham

acup

un

ctu

re1

5m

in1

5m

inM

easu

rerC

BF

by

rest

/EA

Tc-

99

mE

CD

bra

inS

PE

CT

usi

ng

asa

me-

do

sesu

btr

acti

on

met

ho

d

Acu

pu

nct

ure

atle

ftL

I4in

crea

sed

rCB

Fin

the

rig

ht

hem

isph

ere

(th

eri

gh

tp

arie

tal

lobe,

ap

art

of

the

rig

ht

mid

dle

po

stte

mp

ora

lg

yru

san

dth

eri

gh

tin

feri

or

occ

ipit

allo

be)

P<

0.9

Wo

oan

dN

am(1

28

)2

01

01

0C

A(r

igh

tL

I4L

R3

)C

A(l

eft

LI4

LR

3)

20

min

20

min

Mea

sure

chan

ges

inb

lin

dsp

ot

map

pin

g(m

anual

per

imet

ry)

Acu

pu

nct

ure

ipsi

late

ral

sid

e!

bli

nd

spo

tm

ap#,

con

tral

ater

alco

rtic

alac

tivit

y"

Acu

pu

nct

ure

con

tral

ater

alsi

de!

bli

nd

spo

tm

ap",

contr

alat

eral

cort

ical

acti

vit

y#

N/A

BO

LD

,blo

od

oxygen

level

dep

enden

t;rC

BF

,re

gio

nal

cere

bra

lblo

od

flow

;S

PE

CT

,si

ngle

photo

nem

issi

on

com

pute

dto

mogra

phy;

BU

,C

alcu

lus

Bovis

.Fel

Urs

i;E

CD

,et

hy

lcy

stei

nat

ed

imer

.

348 Acupuncture in Korea

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evidence of rigorous randomized controlled trials showed that

there was no compelling evidence to show that acupuncture is

effective in stroke rehabilitation (144). Yet, as clinicians who

treat patients with acupuncture, we have success in these treat-

ments where no efficacy is found. This is due to a complex set

of problems at the heart of which is the establishment of a

standard for the treatment of the control group. This article is

not a systematic review; rather it is an overview of the clinical

trials, presented in the hopes of introducing overall informa-

tion about clinical studies in Korea to the English-speaking

world.

This review describes a number of clinical studies that were

performed to compare the therapeutic effects of different kinds

of acupuncture under certain conditions. Conventional acu-

puncture was compared with electric acupuncture, auricular

acupuncture, BVA and manipulation. These comparative stud-

ies of different kinds of acupuncture are required in order to

proceed with the most adequate method in the future. Since

more than two therapies were simultaneously performed to

treat the disorders in some studies, it is not likely to demon-

strate the efficacy of pure acupuncture apart from other treat-

ments. For instance, given that both acupuncture and

auricular acupuncture were effective to treat tension-type

headache patients, it is impossible to clarify the extent of the

therapeutic benefit of acupuncture. Therefore, in order to

investigate the therapeutic benefits of acupuncture, it is neces-

sary to establish a group treated by acupuncture alone.

From the above clinical studies, it is possible to summarize

the originality of Korean acupuncture by describing both of

its characteristic approaches—individualized and practical.

Firstly, a number of clinical studies in Korea have shown the

benefits of individualized acupuncture treatment, such as

Saam, Taegeuk or Eight constitutions acupuncture (35). Patel

et al. (145) noted that individualized treatments significantly

favored acupuncture, whereas formulaic approaches, in which

all the patients received the same treatment, showed no signi-

ficant difference. However, in order to demonstrate its superi-

ority, more rigorous and well-designed randomized controlled

clinical trials are urgently needed. Secondly, HA-like BVA

have been used to treat a variety of painful conditions. HA is

a new method of acupuncture where distilled herbal decoction

is extracted and purified to be administered to an acupuncture

point for stimulation. HA simultaneously exerts pharmaco-

logical actions from a bioactive compound isolated from her-

bal medicine and mechanical actions from acupuncture

stimulation. The Korean medical world considers HA as a

promising therapeutic method for various diseases (84,140).

An individualized approach based on constitutional energy

traits have been widely applied to a number of clinical trials

in Korean medicine. HA have also been developed as a

new therapeutic modality using integrated and practical

approaches. Korean acupuncture in its own way is making a

contribution to the emerging need for individualized and integ-

rated approaches to acupuncture. In closing, we stress the need

for randomized controlled studies and express our hope that

this view into Korean traditional medical practice will lead to

evidence-based studies that could form the basis for a meta-

analysis in the near future.

Acknowledgments

We are grateful to Dr. Nam-Il Kim for presentation of the

Figures. This study was supported by a grant of the Oriental

Medicine R&D Project, Ministry of Health & Welfare,

Republic of Korea (0405-OM00-0815-0001).

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59. Wang WH, Ahn KB, Lim JK, Jang HS. Clinical investigation comparedwith the effects of the bee venom acupuncture on knee joint withosteoarthritis. J Kor Acu Mox Soc 2001;18:35–47.

60. Kim JH, Lee JD. Clinical research of bee venom acupuncture analgesiceffect on osteoarthritis. J Kor Acu Mox Soc 1999;16:25–37.

61. Hwang YJ, Lee GM, Hwang WJ, Seo EM, Jang JD, Yang GB, et al. Clin-ical research of bee venom acupuncture effects on rheumatoid arthritis.J Kor Acu Mox Soc 2001;18:33–42.

62. Hwang WJ. Clinical study of rheumatoid arthritis. J Kor Acu Mox Soc1995;12:281–90.

63. Shim JC, Kim YJ, Suh JK, Chung CW, Kang GB, Hwang YH, et al.Clinical study of electrical stimulation of the peripheral nerve. J KorSoc Anesth 1984;17:126–35.

64. Cho KS, Kim SC, Lee JY, Sohn SS, Park DS. The effect of acupunctureon the post-thoracotomy pain control. Kor J Thorac Cardiovasc Surg1997;30:187–94.

65. Choi H, Moon SJ. A clinical study on reviewing pain of acupuncture.J Kor Acu Mox Soc 1983;1:40–5.

66. Kim YI, Kim YH, Lee H, Lee BR. Clinical comparison studies on26 cases of patient with ankle sprain with acupuncture treatmentgroup and trigger point treatment group. J Kor Acu Mox Soc 2001;18:50–9.

67. Bang DH, Chang HS, Han SW, Ryu SH, Lee IG. A clinical observationof patients with humeral lateral epicondylitits. J Kor Oriental Med Soc1992;13:224–9.

68. Seung JW, Ahn CB. A study on human immune activity of the arthritisand multi-neuritis through different moxibustion methods. J Kor AcuMox Soc 1991;8:395–403.

69. Choi YT, Lee HJ. A study of acupuncture treatment effect on the acutegout disease. J Kor Oriental Med Soc 1989;10:132–7.

70. Ahn KB, Wang WH, Lim JK, Jang HS. Clinical study of acupunctureeffect by measuring amperage from chong points. J Kor Acu Mox Soc2001;18:13–21.

71. Ha CH, Han SG, Cho MR, Ryu CR, Lee BR. A clinical study on 29 caseswith stroke treated by common acupuncture therapy and scalp acupunc-ture. J Kor Acu Mox Soc 2001;18:82–90.

72. Lee KJ, Koo BS, Kim YS, Kang JK, Moon SK, Koh CN, et al. Effects ofvenesection at the Sybsun-points on blood pressure and body temperaturein patients with stroke. J Kor Oriental Med Soc 2000;21:62–7.

73. Park SU, Moon SK, Koh CN, Cho KH, Kim YS, Bae HS, et al. The clin-ical study of the effect of electrical stimulation at Sugu-Sungjang points(GV26-CV24) on blood pressure, pulse, and cerebral blood flow inischemic stroke patients. Kyunghee Med 1997;13:390–403.

74. Ahn CH, Bae HS, Roh JH, Moon SK, Koh CN, Cho KH, et al. Effects ofauricular acupuncture on the mild hypertension. J Kor Oriental Med Soc2000;20:93–7.

75. Kang BJ, Moon SK, Koh CN, Cho KH, Kim YS, Bae HS, et al. Clinicalresearch on the depressing effect of acupuncture therapy at Kokchi(LI11) and Chocksamni (ST36) in acute stroke patients with hyperten-sion. J Oriental Med 1998;3:43–50.

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76. Moon SK, Cho KH, Koh CN, Kim YS, Bae HS, Lee KS. Effects ofopposing needling on upper limb on cerebral blood flow in ischemicstroke patients. Kyunghee Med 2000;16:94–101.

77. Song JC, Jung SH, Lee JS, Kim SS, Shin HD. Clinical study of the effectof electroacupuncture on shoulder pain of the cerebrovascular attackpatients. J Oriental Rehabil Med 1999;9:41–57.

78. Yin CS, Nam SS, Kim YS, Lee JD, Kim CH, Koh HK. Effects of honeybee venom acupuncture therapy on poststroke hemiplegic shoulder pain.J Kor Inst Herbal Acu 2000;3:213–32.

79. Kang JC, Baik TH. A comparative study of effects using physical treat-ment apparatus and diagnosis of shoulder pain on cerebrovascular attackpatients. Kor Int Med Soc 1999;20:244–60.

80. Lee SH, Lee YH. Clinical study with thermography on shoulder handsyndrome after stroke. J Kor Oriental Med Soc 1997;18:25–39.

81. Kang KS, Jeong EJ, Moon SK, Koh CN, Cho KH, Kim YS, et al. Clinicalstudy on the effects of moxibustion for post-stroke voiding dysfunction.J Kor Oriental Med Soc 2000;21:236–41.

82. Lee YK, Lee BR. Clinical studies on 72 cases of patient with facialparalysis. J Kor Acu Mox Soc 1998;15:1–12.

83. Lee SW, Han SW. Clinical study of facial nerve paralysis throughelectroacupuncture treatment. J Kor Acu Mox Soc 1999;16:149–63.

84. Yun JH, Yook TH, Song BY. The effect of Hominis placenta herbalacupuncture. J Kor Inst Herbal Acu 2000;3:89–99.

85. Lee KM. Combined treatment method for peripheral facial paralysis:report on 85 cases. J Kor Acu Mox Soc 1998;15:21–9.

86. Cho EH, Cho NG, Hur TY, Cheon MN. Clinical evaluation of acupunc-ture and herb medication on Bell’s palsy by DITI. J Kor Acu Mox Soc2000;17:19–30.

87. Song BY, Sohn IC, Kim KS. Clinical diagnostic study on prognosis ofBell’s palsy with the digital infrared thermal image. J Kor Acu MoxSoc 1999;16:13–35.

88. Kang MJ, Kim KH, Hwang HS. Comparative clinical study betweenoriental medicine and oritental western medicine treatment on facialnerve paralysis. J Kor Acu Mox Soc 2000;17:55–66.

89. Kim CG, Park SD, Kim KH. Comparative study between acupunctureand acupuncture-oriental herb medicine treatment on facial nerve para-lysis. J Kor Acu Mox Soc 2001;18:10–22.

90. Kwon SJ, Song HS, Kim KH. The influence of moxibustion and basiccompound therapy on peripheral facial paralysis. J Kor Acu Mox Soc2000;17:160–71.

91. Sim MK, Hwang WJ, Lim KS. Clinical study of acupuncture and vene-section on acute infectious conjunctivitis. J Kor Oriental Med Soc1993;14:133–8.

92. Kim KJ, Chae BY. A clinical analysis on glaucoma, cataract and causingblindness by oriental medical therapy. J Oriental Med Surg OphthalmolOtolaryngol 1997;10:340–8.

93. Choi DY, Kim JK, Kim SS. A clinical study of the effect of acupunctureand moxibustion treatment for the near-sightedness. Kor. J Oriental MedPathol 1999;13:119–23.

94. Chae BY. The clinical study on decrease of visual acuity. J Oriental Med1997;2:93–108.

95. Kim SS, Kim JK, Choi DY. A clinical study of the effect of orientalmedicine and acupuncture treatment for the amblyopia. J Kor OrientalMed Soc 2000;20:23–8.

96. Kim SI, Park DI. A clinical study on allergic rhinitis. Kor Int Med Soc1998;19:353–63.

97. Seo JC, Lee JD. Clinical study on chronic paranasal sinitis by nasalacupuncture. J Kor Acu Mox Soc 2000;17:99–105.

98. Kim YB, Yoon SH. A clinical observation of the nasal acupuncture ther-apy on nasal obstruction. J Oriental Med Surg Ophthalmol Otolaryngol1999;12:205–11.

99. Park GH, Han YM, Ahn SH, Hwang CH. Effect of tinnitus after bleeding,acupuncture, moxa, and laser treatment. J Oriental Med Surg OphthalmolOtolaryngol 1999;12:396–407.

100. Kim GJ. A clinical analysis on the treatment efficiency of tinnitus bytypes of bianzheng. J Oriental Med Surg Ophthalmol Otolaryngol1999;12:182–8.

101. Lee HB, Oh SJ, Kim SK. Clinical study on otitis media with effusion byacupucnture. J Kor Acu Mox Soc 2001;18:92–8.

102. Chae BY. The clinical study of acne patients. J Oriental Med SurgOphthalmol Otolaryngol 1998;11:251–68.

103. Kim JS, Kim GJ. The clinical observation of 8 cases of acnes diseases.J Oriental Med Surg Ophthalmol Otolaryngol 2001;14:66–75.

104. Byun JY, Ahn SG. Effects of the auricular acupuncture on the blood pres-sure. J Kor Oriental Med Soc 1996;17:418–26.

105. Lee BH, Kim CH, Seo JC, Youn HM, Jang KJ, Song CH, et al. Theeffects of moxibustion on blood pressure of hypertentsion patients.J Kor Acu Mox Soc 2001;18:70–6.

106. Hwang BT, Hwang WJ, Shin SY. Clinical research of the acupuncturetherapy on stop-smoking. J Kor Acu Mox Soc 1994;11:265–74.

107. Ahn SG, Kim SC, Lee MH, Kim KS. A clinical research of the auricularacupuncture therapy. J Kor Acu Mox Soc 1993;10:175–90.

108. Choi SC, Hwang CY. Effects on stop of smoking in adolescents by auri-cular acupuncture therapy. J Oriental Med Surg Ophthalmol Otolaryngol1999;12:369–85.

109. Choi DY. Clinical study of effect of auricular acupuncture on stopingsmoking. J Kor Acu Mox Soc 1996;13:202–11.

110. Lee JD, Choi DY, Park DS. Clinical research of the auricular acupuncturetherapy on stop-smoking. J Kor Acu Mox Soc 1992;9:17–29.

111. Kim JD, Kwan CC, Lim NC. Clinical study of the effect of ear acupunc-ture on 233 alcoholics. J Kor Oriental Med Soc 1992;13:124–50.

112. Lee JH, Kim YC, Woo HJ. Clinical study on 133 cases of temperance(quit-drinking) therapy. J Oriental Med 1998;3:59–69.

113. Park JH, Peun SH. Clinical study of auricular acupuncture and herbalmedicine in the treatment of alcoholism. J East-West Med 1996;21:1–15.

114. Lee SR, Lee KG. A clinical research of abdominal obesity by the electricacupuncture therapy. J Kor Acu Mox Soc 1996;17:336–44.

115. Jeong SH, Nam SS, Kim YS, Lee JD, Choi DY, Koh HK, et al. A clinicalstudy on case of nine obesity patients by elecroacupuncture therapy. J KorAcu Mox Soc 1999;16:39–56.

116. Lee ES, Kim YS. The effect of acupuncture treatment on weight regula-tion. J Oriental Rehabil Med 1996;6:365–77.

117. Kim YS, Kim CH, Kim KS. Effect of auricular acupuncture on post-operative nausea and vomiting. J Kor Acu Mox Soc 1996;17:331–6.

118. Kim KS, Kim DS, Shin KI, Kim YS. Effect of electric acupuncturestimulation of PC6 and PC7 antiemetic point on postoperative nauseaand vomiting. J Kor Soc Anesth 1995;28:433–40.

119. Kim SW, Nam SS, Lee SK, Kim KS, Kim JK. The effects of elec-trostimulation on acupuncture loci upon duration of labor in primipara.Kyunghee Med 1999;15:198–202.

120. Kim JK, Kim SW. A clinical study on the effects of acupuncture anes-thesia upon 31 cases of curettage. Kyunghee Med 1992;8:276–85.

121. Hwang WJ, Yang GB. The study on the effects of moxibustion on peri-pheral blood circulation. J Kor Oriental Med Soc 1997;18:499–505.

122. Ahn YM, Ahn SY, Doo HK. The change of temperature of external gen-italia at the patients with impotence by using penile DITI. Kyunghee Med1998;14:79–88.

123. You WK, Lee MJ, Oh JG. The effects of auricular acupuncture for obes-ity on the change of hormone and energy metabolism during weightcontrol of veteran taekwondo players. J Oriental Rehabil Med 2000;10:133–45.

124. Park KM. Influence of acupuncture stimulation on electrical resistanceunder adiaphoresis induced by regional anaesthesia. J Kor Acu MoxSoc 2000;17:130–8.

125. Youn JH, Hwang MS, Bae GT, Lee SH, Lee SD, Jang JH, et al. The newfinding on BOLD response of motor acupoint KI6 by fMRI. J Kor AcuMox Soc 2001;18:5.

126. Kim ID, Oh HH, Song HC, Bom HS, Byun JY, Ahn SG. The nuclearmedical study on the effect of ST36 electroacupuncture on cerebral bloodflow. J Kor Acu Mox Soc 2001;18:18–26.

127. Oh HH, Byun JY, Kim ID, Ahn SG, Mun HC, Hwang WJ, et al. The nuc-lear medical study on the effect of LI4 acupuncture on cerebral bloodflow. J Kor Acu Mox Soc 2001;18:46–54.

128. Woo YM, Nam Y. The practical study of the contralateral therapeutictheory in acupuncture approach about the changes in the blind spotmapping pre and post acupuncture. J Oriental Med Surg OphthalmolOtolaryngol 2000;13:200–10.

129. Lee SH, Lee JD, Lee YH. Thermographic study on the effects of acu-puncture at Hapkok (LI4) in normal cases. J Kor Acu Mox Soc1995;12:49–64.

130. Sohn IC, Kim DM, Kim HJ, Lee HS, Kim KS. Effects on thethermal changes of Hap-Kok (LI4) and Chun-Choo (ST25) followingacupuncture on Hap-Kok (LI4) in man. J Kor Acu Mox Soc 1998;19:66–88.

131. Han MC, Chung HC, Koo ST, Ahn SH, Kim KS, Sohn IC. Effects of acu-puncture at left Hap-kok (LI4) on the skin temperature changes ofYoung-Hyang (LI20) area. J Kor Acu Mox Soc 1999;16:57–68.

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132. Song JS, An SH, Kim JH, Kim KS, Sohn IC. Effects on the thermalchanges of Kok-Chi (LI4) and Yong-Hyang (LI20) following acupunc-ture on Hap-Kok (LI4) in man. J Kor Acu Mox Soc 1998;19:271–95.

133. Han MJ, Chung HC, Koo ST, Ahn SH, Kim KS, Sohn IC. Effects of acu-puncture at left Hap-Kok (LI4) on the skin temperature changes ofYoung-Hyang (LI20) area. J Kor Acu Mox Soc 1999;16:57–68.

134. Hwang JH, Ahn SH, Kim KS, Sohn IC. Effects of acupuncture atHap-Kok (LI4) on the thermal changes of abdominal surface in man.J Kor Acu Mox Soc 1999;16:445–72.

135. Yun JH, Hwang CY, Lim KS. Effects on the thermal changes of the facefollow electroacupuncture on Hapkok (LI4) and Samgan (LI3). J Ori-ental Med Surg Ophthalmol Otolaryngol 1999;12:222–47.

136. Lee SW, Lee JH, Song BY, Yook TH. The effect on the thermal changesof an acupuncture point area with the Young-Su-Bo-Sa acupuncturestimulation. J Kor Acu Mox Soc 2001;18:161–74.

137. Song BY, Sohn IC, Kim KS. Effects on the thermal changes of thecorresponding meridian points following the left or right rotaryacupuncture stimulation. J Kor Acu Mox Soc 1999;16:385–402.

138. Song BY, Yook TH. Effect of the thermal changes of Five-shu-points ofthe lung meridian with acupuncture stimulation on Taeyon (L9). J KorAcu Mox Soc 2000;17:219–32.

139. Kim YH, Song BY, Yook TH. Effects of the thermal changes of theTaeyon (L9) and the Chungbu (L1) area following acupuncturestimulation on Taeyon (L9) in man. J Kor Acu Mox Soc 2001;18:77–91.

140. Yook TH, Song BY, Shim MS, Kim BH, Park JJ, Yun JH. Effects on thelocal thermal change following herbal acupuncture on DITI. J Kor AcuMox Soc 2000;17:57–68.

141. Kim HJ, Byun JY, Ahn SG, Lee GM, Park YH, Kim KS. Effects on thethermal changes of the ankle region following acupuncture on Wu-hu.J Kor Acu Mox Soc 2001;18:40–9.

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Received January 26, 2005; accepted July 4, 2005

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