The President’s Cancer Panel2004/2005 Series

Translating Research to Reduce the Burden of Cancer

Margaret L. Kripke, Ph.D.January 25, 2005

The President’s Cancer Panel

• National Cancer Act of 1971• Oversees the National Cancer Program• Three Members• Meet Four Times per Year• Reports to the President of the United States

Translating Research to Reduce the Burden of Cancer

• August 30, 2004–University of California at San Francisco

• September 27, 2004–The Ohio State University

• November 1, 2004–M.D. Anderson Cancer Center

• January 24, 2005–Memorial Sloan-Kettering Cancer Center

Laboratory Clinic Community

Laboratory to Clinic–Barriers• Research culture• Infrastructure• Funding sources • Conflict of interest• Complexity of clinical trials

Research Culture

• Differing cultures of physicians and scientists

• Lack of incentives for team science• Creation of knowledge vs. application• Departmental structure

Infrastructure

• Access to human samples• Interactive databases• Conflict of interest• Clinical trials support

Funding Sources

• Need for “gap” funding• Demands on clinicians’ time• Need for partnerships

Conflict of Interest/Intellectual Property

• No universal standards• Commercialization• Public trust

Complexity of Clinical Trials

• IRB issues• Informed consent• Changing regulations• HIPAA• Trial design

Clinic to Community–Barriers

• Public trust• Communication• Community involvement• Cost

Where Do We Go From Here?

• Develop recommendations• Deliver Report to President• 2005/2006 Series–Focus Groups on

Recommendations