the south asian cochrane network
DESCRIPTION
The South Asian Cochrane Network. Dr. Prathap Tharyan MD, MRCPsych Professor of Psychiatry Editor, Cochrane Schizophrenia Group Coordinator, South Asian Cochrane Network Prof. BV Moses Centre for Research and Training in Evidence Based Health Care Christian Medical College, Vellore, India. - PowerPoint PPT PresentationTRANSCRIPT
![Page 1: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/1.jpg)
The South Asian Cochrane Network
Dr. Prathap Tharyan MD, MRCPsychProfessor of Psychiatry
Editor, Cochrane Schizophrenia GroupCoordinator, South Asian Cochrane Network
Prof. BV Moses Centre for Research and Training in Evidence Based Health Care
Christian Medical College, Vellore, India
![Page 2: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/2.jpg)
EVIDENCE BASED MEDICINE
• “Evidence-based medicine is the integration of best research evidence with clinical expertise and patient values” (Sackett, et al 2001)
![Page 3: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/3.jpg)
Why do we need EBM?
Wherever health care is provided and used, it is essential to know which interventions work, which do not work, and which are likely to be harmful.
This is especially important in situations where health problems are severe and the scarcity of resources makes it vital that they are not wasted
EBM has a particular relevance to the developing world
![Page 4: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/4.jpg)
The chronology of an infection
Bitten by the Cochrane bug (Clive Adams) in 1995,in Oxford, UK
Protocol for systematic review published in Issue 1, 1996
Review published in Issue 1, 1997
Updated twice, in 2002 and 2005
![Page 5: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/5.jpg)
An April Fool’s Day joke?
Kenneth Warren Prize 2002
Cochrane Colloquium in Stavanger
![Page 6: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/6.jpg)
![Page 7: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/7.jpg)
Statutory Warning!
Attending Cochrane Colloquia may be fatal
to your free time in years to come
![Page 8: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/8.jpg)
The Cochrane Collaboration
Collaborative Review Groups
Fields
The Consumer Network
Centres
Steering Group Methods
Groups
![Page 9: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/9.jpg)
South African
Australasian
Chinese
Brazilian
Nordic
German
ItalianIberoamerican
Dutch
UK
Canadian
New England
San Francisco
NZ Branch
Thai CochraneNetwork
SACN
Cochrane CentresCochrane Centres
Chinese
![Page 10: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/10.jpg)
Exploratory meeting: Goa December 2004
![Page 11: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/11.jpg)
South Asian Cochrane Network
Exploratory meeting at Goa; December 2004
![Page 12: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/12.jpg)
The South Asian Cochrane Network
![Page 13: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/13.jpg)
Network Sites in India
Vellore
ChennaiManipal
Mumbai
Delhi
Chandigargh
![Page 14: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/14.jpg)
www.cochrane-sacn.org
![Page 15: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/15.jpg)
Prof BV Moses Centre for Clinical Trials & EBM
![Page 16: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/16.jpg)
![Page 17: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/17.jpg)
Network Sites in Pakistan
![Page 18: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/18.jpg)
Network Site in Sri Lanka
Ragama
![Page 19: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/19.jpg)
Network Site in Bangladesh
![Page 20: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/20.jpg)
Goals of the SACN
Goal 1: To raise awareness about the Cochrane Collaboration and evidence based practice in South Asia
Goal 2: To train and support contributors to the Cochrane Collaboration in South Asia
Goal 3: To promote access to The Cochrane Library for South Asia
Goal 4: To ensure a sustainable structure for the South Asian Cochrane Network
Goal 5: To represent and advocate for high quality research in South Asia
![Page 21: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/21.jpg)
To train and support contributors to the Cochrane Collaboration in South Asia
Protocol Development Workshop CMC Vellore, July 2004
![Page 22: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/22.jpg)
![Page 23: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/23.jpg)
Protocol Development Workshop, Aga Khan University, Karachi, April 2006
![Page 24: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/24.jpg)
Sensitization workshops
18 in different parts of India, Sri Lanka since 2005
Post Graduate Institute; Colombo Dec 05
![Page 25: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/25.jpg)
Review Completion workshops
![Page 26: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/26.jpg)
SACN participation in systematic reviews (Issue 3, 2005)
Country Reviews Protocols Titles Total
India 11 19 33 63
Pakistan 1 3 9 13
Sri Lanka 2 1 3
Nepal 2 2
Combined 15 23 42 81
![Page 27: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/27.jpg)
SACN participation in systematic reviews (Issue 3, 2006)
Country Reviews Protocols Titles Total
India 15 23 39 77
Pakistan 3 6 9 18
Sri Lanka 2 2 3 7
Nepal 2 2
Combined 22 31 52 104
![Page 28: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/28.jpg)
Growth of contributors in India
2000 2002 2003 2004 2005 2006
Authors 11 15 20 31 42 80
Editors 2 1 2 5 5 5
Others 2 15 18 28 19 35
Total 19 31 40 64 76 120
![Page 29: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/29.jpg)
The Cochrane Collaboration’s response to the tsunami, 2004
![Page 30: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/30.jpg)
![Page 31: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/31.jpg)
![Page 32: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/32.jpg)
![Page 33: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/33.jpg)
Nagapattinam District 73 affected villages 1,96,184 population 36,860 homes 6053 human lives lost 5023 livestock perished 40 relief camps 36,664 people in camps
![Page 34: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/34.jpg)
Evidence for interventions to be used after disasters?
Media pressure to provide counselling to survivors
![Page 35: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/35.jpg)
Psychological debriefing for preventing post traumatic stress disorder (PTSD) (Cochrane Review). Rose S, Bisson J, Wessely S. In: The Cochrane Library, Issue 4, 2003.
![Page 36: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/36.jpg)
Brief single session debriefing increases odds of PTSD in long term
![Page 37: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/37.jpg)
![Page 38: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/38.jpg)
The Cochrane Collaboration & the Asian tsunami
Tsunami working group Free country-wide access to the Cochrane
Library to all affected countries Evidence based summaries of relevant
effective interventions List of priority reviews that need updating List of interventions that need to be reviewed
www.cochrane.org
![Page 39: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/39.jpg)
![Page 40: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/40.jpg)
![Page 41: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/41.jpg)
![Page 42: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/42.jpg)
![Page 43: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/43.jpg)
Usage statistics of The Cochrane Library (Jan-June 2005)
Country Jan Apr May June
Thailand 632 821 1527 1914
Indonesia 49 363 532 366
India 385 581 603 624
Malaysia 145 231 236 293
Pakistan 24 52 46 66
Sri Lanka 11 33 42 43
![Page 44: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/44.jpg)
Dissemination of Evidence Aid Ministry of Health Indian Council of Medical Research Director General of Health Services Non-governmental aid agencies Following the Mumbai floods Following the earthquake in
Pakistan and Kashmir
![Page 45: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/45.jpg)
![Page 46: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/46.jpg)
Influencing health policy in India Workshop for senior faculty of the Indian
Council of Medical Research (ICMR) (October 10, 2006)
Using Cochrane reviews to inform health policy and care
![Page 47: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/47.jpg)
Primaquine for preventing relapses in people with Plasmodium vivax malariaGalappaththy GN L, Omari AAA, Tharyan P. Cochrane Database for Systematic Reviews Issue 1, 2007
Background Plasmodium vivax infections contribute to a significant proportion
of the malaria infections in many countries. Primaquine is the most widely used drug for treating the dormant liver stage. Different primaquine dosing regimens are in use.
WHO recommends 15 days of Primaquine following chloroquine; India recommends 5 days of primaquine following chloroquine
Objectives To compare primaquine regimens for preventing relapses in
people with P. vivax malaria.
![Page 48: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/48.jpg)
Search strategy We searched the Cochrane Infectious Diseases
Group's Specialized Register (January 2006), CENTRAL (The Cochrane Library 2006, Issue 3), MEDLINE (1966 to October 2006), EMBASE (1974 to January 2006), LILACS (1982 to January 2006), conference proceedings and reference list of articles. We also contacted researchers, the World Health Organization, malaria mailing lists, and selected pharmaceutical companies.
![Page 49: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/49.jpg)
Selection criteria Randomised and quasi-randomised controlled
trials comparing (1) primaquine plus chloroquine with chloroquine alone and (2) the standard primaquine regimen (15 mg/day for 14 days) with other regimens containing primaquine in people with P. vivax malaria.
Data collection & analysis All authors independently assessed trial eligibility
and quality, and extracted data. We calculated odds ratios (OR) with 95% confidence intervals (CI) for dichotomous data, and used the random effects model if there was significant heterogeneity.
![Page 50: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/50.jpg)
Main resultsNine RCTs (3423 participants) met the
inclusion criteria. Most from IndiaPakistan, Afganistan, Thailand
![Page 51: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/51.jpg)
![Page 52: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/52.jpg)
![Page 53: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/53.jpg)
![Page 54: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/54.jpg)
Reviewers' conclusions Primaquine (15 mg/kg/day for 14 days) plus
chloroquine is more effective than chloroquine alone or primaquine (15 mg/kg for 5 days) plus chloroquine in preventing relapses of P. vivax malaria.
Primaquine (five days) plus chloroquine appears no better than chloroquine.
Countries advocating the five-day regimen should follow the World Health Organization's recommendation of the 14-day primaquine plus chloroquine regimen.
Alternative regimens need to be evaluated in randomised controlled trials, which should also consider variations in regional P. vivax strains and the possibility of primaquine resistance, re-infection, and adherence in those who relapse.
![Page 55: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/55.jpg)
Promoting access to The Cochrane Library
![Page 56: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/56.jpg)
Promoting access to the Cochrane Library Many countries have a national provision Many countries have free access via Bireme,
HINARI, INASP/PERI India in low income group but not eligible Previous attempts to get ICMR/DBT to purchase
a national subscription had failed ICMR/DST purchased national subscription to
Cochrane Library- deal brokered by SACN with John Wiley & Sons
![Page 57: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/57.jpg)
“Developing countries like India, with limited resources and many competing priorities, are even more in need than developed countries of the wherewithal to access the best scientific evidence in order to make informed decisions about health care policy and practice, and to improve the health of what amounts to one sixth of humanity. The ICMR has shown tremendous leadership and commitment in getting to this point…..”
(Dr. Tikki Pang, Director, Research Policy and Cooperation, World Health Organization)
![Page 58: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/58.jpg)
Free access to the Cochrane Library to anyone in India
The Telegraph, Kolkatta; Feb 3, 2007
![Page 59: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/59.jpg)
Free access to the Cochrane Library to anyone in India
![Page 60: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/60.jpg)
Free access to the Cochrane Library to anyone in India
![Page 61: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/61.jpg)
ICMR Advanced Centre for Research and Training in
Evidence Based Healthcare at CMC Vellore
![Page 62: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/62.jpg)
Goal I: Build capacity among network sites of the South Asian Cochrane Network
Theme 1 Building/increasing capacity, support and co-ordination of network sites in India
Activity 1.1 Establish a ‘train-the-trainers’ program to build training capacity at the Network sites across India
Activity 1.2 Co-ordinate Cochrane systematic review training
activities in India Activity 1.3 Monitor Cochrane Systematic review training
activities in India Activity 1.4 Identify areas of strengths in network sites and
facilitate the development of programmes that optimally use these strengths to design activities that further the overall goals of the proposal
![Page 63: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/63.jpg)
GOAL 2: Identifying and prioritizing
locally relevant areas for research Theme 2 Prioritizing systematic reviews and identifying
evidence-practice gaps Activity 2.1 In collaboration with clinicians, policy makers,
researchers and consumers identify areas where evidence exists but needs to be synthesized in systematic reviews
Activity 2.2 In collaboration with clinicians, policy makers, researchers and consumers identify areas where randomized trials are required
Activity 2.3 Encourage funding agencies / ethics committees to require that evidence from systematic reviews is included in funding applications for randomized trials before new trials are funded / permitted
![Page 64: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/64.jpg)
GOAL 2: Identifying and prioritizing
locally relevant areas for research Theme 3 Training and supporting review authors in India Activity 3.1 Provide introductory sessions / workshops
regarding the role of systematic reviews in healthcare at local, regional and national conferences
Activity 3.2 Provide workshops that train review authors in developing protocols for systematic reviews
Activity 3.3 Provide workshops on basic and advanced statistics in meta-analysis
Activity 3.4 Provide workshops to help authors’ complete systematic reviews
Activity 3.5 Provide mentorship programmes for review authors Activity 3.6 Providing help in running searches for trials and
retrieving trials to include in systematic reviews Activity 3.7 Develop distance learning technology/packages for
systematic reviews
![Page 65: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/65.jpg)
GOAL 2: Identifying and prioritizing
locally relevant areas for research Theme 4 Maintaining a register of published and
unpublished trials from South Asia Activity 4.1 Establish a register of published trials from Indian
and South Asian Medical and International journals conducted in India and South Asia
Activity 4.2 Hand-search South Asian journals that are not indexed to identify clinical trials
Activity 4.3 Search conference proceedings from South Asia for unpublished trials
Activity 4.4 Establish a register of dissertations to identify unpublished trials
![Page 66: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/66.jpg)
GOAL 3 Informing healthcare decisions through the uptake of evidence from systematic reviews
Theme 5 Promoting use of The Cochrane Library Activity 5.1 Publicize the national provision to The
Cochrane Library Activity 5.2 Provide training on using The Cochrane
Library Activity 5.3 Evaluate existing training materials for The
Cochrane Library and develop additional training materials as required
![Page 67: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/67.jpg)
GOAL 3 Informing healthcare decisions through the uptake of evidence from systematic reviews
Theme 6 Disseminating information in The Cochrane Library
Activity 6.1 Prepare and disseminate Evidence Updates (two-page summaries of Cochrane reviews) in areas of national health priority
Activity 6.2 Prepare and disseminate introductions to evaluating systematic reviews and Evidence Updates
Activity 6.3 Evaluate use of Evidence Updates by clinicians
![Page 68: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/68.jpg)
GOAL 3 Informing healthcare decisions through the uptake of evidence from systematic reviews
Theme 7 Disseminate information about Systematic reviews, The Cochrane Library and Evidence Based Practice
Activity 7.1 Write articles in the lay press on evidence based practice
Activity 7.2 Write articles in medical journals on understanding and undertaking systematic reviews, and on evidence based practice
Activity 7.3 Encourage medical journal editors to include information about and links to the Cochrane Library, the Cochrane Collaboration and evidence based resources, and include evidence
based summaries in journal websites and in print editions
![Page 69: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/69.jpg)
GOAL 4: Increasing capacity and skills for evidence-based practice Theme 7 Increase capacity among policy makers to
access, appraise, and implement evidence based policy Activity 7.1 Hold workshops for policy makers on the role of
systematic reviews, the Cochrane Library and other EBM resources in providing reliable evidence on interventions used in healthcare
Activity 7.2 Include policy makers in workshops that support the production of systematic reviews
Activity 7.3 Appraise national guidelines for the inclusion of evidence-based recommendations
Activity 7.4 Attempt to change policy through dissemination of reliable evidence from systematic reviews when needed
![Page 70: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/70.jpg)
GOAL 4: Increasing capacity and skills for evidence-based practice Theme 8 Increasing capacity among clinicians to access,
appraise and implement evidence based practice Activity 8.1 Hold workshops in local, regional and national
conferences on evidence based practice Activity 8.2 Develop distance education tools in evidence based
practice and on auditing clinical practice against evidence-based guide lines
Activity 8.3 Identify barriers to evidence-based practice and develop strategies to implement such practice
Activity 8.4 Introduce modules on systematic reviews, critical appraisal and evidence based practice in undergraduate and postgraduate curricula
Activity 8.5 Develop and offer fellowships and short courses in research methods, critical appraisal, accessing evidence based guidelines and using evidence from systematic reviews
Activity 8.6 Attempt to get systematic reviews accredited as a legitimate research activity for post-graduate dissertations and MSc training programmes
![Page 71: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/71.jpg)
GOAL 5: Improving the conduct and reporting of research in India Theme 9 Encourage the prospective registration of
clinical trials in India and the region Activity 9.1 Collaborate with the WHO International Clinical
Trials Registry Platform and the Indian Clinical Trials Register Activity 9.3 Evaluate the quality of conduct and reporting of
trials from India Activity 9.3 Strengthen the functioning of the Indian
Association of Medical Journal Editors Activity 9.4 Facilitate learning in the planning, implementing
and the conduct of clinical trials that are scientifically valid. Activity 9.5 Facilitate learning of ethical issues in the conduct
and reporting of clinical trials
![Page 72: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/72.jpg)
GOAL 5 Improving the conduct and reporting of research in India Theme 10 Developing capacity for methodological
research in evaluating healthcare interventions Activity 10.1 Conduct methodological research in the
area of systematic reviews of interventions Activity 10.2 Undertake systematic reviews of diagnostic
tests Activity 10.2 Offer PhD programmes in evidence based
healthcare research Activity 10.3 Conduct pragmatic trials of
interventions when there is limited or no evidence
![Page 73: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/73.jpg)
GOAL 6 Contributing to the Cochrane Collaboration and coordinating Cochrane activities in South Asia Theme 11 Establishing a South Asian Cochrane Centre
and Network Activity 11.1 Establish a South Asian Cochrane Centre and
Network with its coordinating centre at CMC Vellore as an independent Centre of the Cochrane Collaboration
Activity 11.2 Integrate training and support activities within all countries in South Asia
Activity 11.3 Host the mid-year meeting of Cochrane Centre Directors and Cochrane Collaboration Steering Group in Vellore in April 2008
Activity 11.4 Organize an annual EBM seminar/conference in different locations in India and the region
![Page 74: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/74.jpg)
Lessons learned
“Never doubt that a small group of thoughtful, committed citizens can change the world. Indeed, it’s the only thing that ever has.”
[Margaret Mead]
![Page 75: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/75.jpg)
The power of collaboration
![Page 76: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/76.jpg)
EVIDENCE BASED MEDICINE
•“Evidence-based medicine is the integration of best research evidence with clinical expertise and patient values” (Sackett, et al 2001)Challenges:
Generalization of Evidence
Incorporating patient's values
Particularizing the Evidence
![Page 77: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/77.jpg)
PROBLEMS WITH SYSTEMATIC REVIEWS & EBM No evidence of effect vs. Evidence of no
effect Evidence versus recommendations Evidence based medicine versus
Evidence based health care Conflicts of interest
![Page 78: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/78.jpg)
FAITH OR FATE BASED MEDICINE
![Page 79: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/79.jpg)
Traditional community resources for mentalhealth: a report of temple healing from India
BMJ 2002;325:38-40
![Page 80: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/80.jpg)
•“Evidence-based medicine is the integration of best research evidence with clinical expertise and patient values” (Sackett, et al 2001)
![Page 81: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/81.jpg)
Join us:www.cochrane-sacn.org
Protocol Development Workshop: June 25-27, 2007
CMC Vellore, INDIA
![Page 82: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/82.jpg)
EVIDENCE BASED MEDICINE
“GOOD CLINICAL MEDICINE WILL ALWAYS BLEND THE ART OF UNCERTAINTY WITH THE SCIENCE OF PROBABILITY”
OSLERUsing GOOD QUALITY SYSTEMATIC REVIEWS TO PROVIDE EVIDENCE will increase the amount of science in the blend
If we produce evidence relevant to us, then EBM will have some relevance in the region
![Page 83: The South Asian Cochrane Network](https://reader031.vdocument.in/reader031/viewer/2022012918/56812a9f550346895d8e60df/html5/thumbnails/83.jpg)