The VIZIER projectThe VIZIER project

Coord. : B. CanardAFMB, CNRS/University of MarseilleFrance

Preparing Europe for the Next Viral Outbreak

Major causes of human death:Major causes of human death:

Most are RNA viruses.

A today alarming situationA today alarming situation

Goal : Identification of new targets from RNA viruses through a structural characterization of the replicative system

Structural Genomics project supported by the European Union

Started in November 2004 up to (at least) October 2008

Means : 25 “partners” (public and corporate research centers)>100 full time researchers involved13 M€ funding by EEC

What is VIZIER?:What is VIZIER?:VIral enZymes InvolvEd in ReplicationVIral enZymes InvolvEd in Replication

A common effort to tackle this issue.

VIZIER members and Partnership

Section 1Bioinformatics

ViralisVaZyMolO

Alexander Gorbalenya

Section 2Virology Xavier De Lamballerie

Section 3Production

Bruno Coutard (vice coordinator)

Section 4Crystallization Alwyn Jones

Section 5Validation

Johan Neyts