the wolfram solution for bioinformatics · organizations using wolfram technology many of the...

THE WOLFRAM SOLUTION FOR

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Contact us and let us work with you to fi nd the right solution for your computational needs.

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BIOINFORMATICS

It struck the perfect balance of being powerful enough and versatile enough to allow our engineering team to develop sophisticated software within, yet the language is easy enough to learn that it’s accessible to our chemists and biologists.

– Brian FrezzaCo-founder & Co-CEO, Emerald Therapeutics

www.wolfram.com/bioinformatics

• Abbott Labs

• Amgen

• Bayer

• Bristol-Myers Squibb

• Eli Lilly

• GlaxoSmithKline

• Max Planck Institutes

• Merck

• Pfi zer

• Roche Diagnostics

ORGANIZATIONS USING WOLFRAM TECHNOLOGYMany of the world’s top companies and organizations rely on Wolfram products to maintain their competitive edge, including 100% of the Fortune 50 companies. Here are just a few:

GET THE WOLFRAM EDGE

Visit our bioinformatics page for a free trial and explore how Wolfram technologies

can further advance your work.

KEY CAPABILITIES

THE WOLFRAM EDGE

Pull in your data or ours, apply sophisticated symbolic and numeric analysis,

visualize, generate interactive reports or instant applications—all in one system,

with one integrated workfl ow.

The Wolfram bioinformatics solution seamlessly integrates specialized

capabilities—like built-in computable genome and protein data, and sequence

alignment—while providing the most automated and reliable computation,

development, and deployment environment available.

■ Rapidly search the human genome

■ Generate sequence alignments in a computable form

■ Quickly visualize large-scale sequence alignments

■ Rapidly compare gene structures

■ Visualize biological reaction networks with Wolfram SystemModeler

■ Model biological systems with SystemModeler

■ Visualize gene interaction networks

■ Generate accurate protein renderings using built- in protein structure, element, and color data

■ Use built-in protein structure data to generate Ramachandran plots, visualize protein folds, and more

■ Rapidly develop and test algorithms

■ Easily integrate legacy data with ready-to-use curated genomic and protein data in a powerful computational environment

■ Construct interactive applications and deploy them immediately with Wolfram CDF Player

■ Built-in access to continually updated human genome and protein data

■ Easy import of Affymetrix, GenBank, EDF, FASTA, NEXUS, PDB, and other data formats

■ Fast exact-match searches for sequences in the human genome

■ Sequence alignment using local (Smith–Waterman) or global (Needleman–Wunsch) methods

■ Integrated access to gene structure information, gene function metadata, and ontology

■ Free-form linguistic input produces immediate results without the need for syntax

■ Advanced string and general list manipulations, including regular expression notation

■ Extensive linking and connectivity capabilities to databases, as well as Java, C, and .NET codes

■ Automatic conversion of compilable Wolfram Language programs into C code, for standalone use or integration with other systems

■ Model biological systems with the built-in BioChem library in SystemModeler

■ Import and export Systems Biology Markup Language (SBML) models with SystemModeler

Quickly develop interactive applications using automatic interface construction.

Protein fold visualizations using built-in protein structure data.

Gene analysis and cross-species comparison via integrated access to Wolfram|Alpha data.

“With Manipulate, you can see the changes

in the parameter values and associated

changes in dynamics, and that makes the

research much more effi cient and saves time.

“Our error rate, in terms of sending incorrect

results to our clients, has decreased by four

orders of magnitude. So we used to have 10

to 15 errors a day in our laboratory. Now, it’s

2 or 3 every year, and that’s a big advantage.

“It’s a remarkably diverse collection of

functionalities.... You’re stunned by the things

it can do. It’s my desert-island application.

– Zhilan FengProfessor, Purdue University

– George Woodrow IIIResearch Specialist, Quest Diagnostics

– David DeBrotaSenior Clinical Research Physician

“The reason why I still use Wolfram technology

and have been using it for all this time is that

it’s a very intuitive, very seamless development

environment. I can go from an idea to a

computational framework where I can get

quick, easy numerical answers. ”

“Using the Manipulate command, I can adjust

the curve to fi t theoretical situations and try

many diff erent experiments quickly. It just adds

precision and accuracy to what we’re doing. ”

– Melih SenerBiophysicist, University of Illinois at Urbana-Champaign

– Tim ShinePhysicianMayo Clinic

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