theteam5 abcc!€¦ · prinng: your,printer,might,not,print,the, same,way,our,printers,do,,so,...

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Imaging and Visualization Group http://ncifrederick.cancer.gov/isp/abcc [email protected] 301-846-7366 3D Biomedical Visualization Quantitative Image Analysis Information Visualization Image Archive NanoStructural Support IVG Works with NCI/FNLCR imaging facilities and investigators Gathers user requirement from domain exports in imaging facilities Collaborates with external imaging communities Adopts new technologies in image analysis and visualization Performs technology development Builds workflows to increase image analysis throughput Develop and maintenances computing infrastructure for image analysis – including common software tool sets, thin clients, and servers The Team ABCC ISP, FNLCR Advanced Biomedical Computing Center Information Systems Program Frederick National Laboratory for Cancer Research

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Page 1: TheTeam5 ABCC!€¦ · Prinng: Your,printer,might,not,print,the, same,way,our,printers,do,,so, make,sure,to,try,a,couple,of,test, prints.Ifthingsaren’taligning quite,right,,experiment

Prin%ng: Your  printer  might  not  print  the  same  way  our  printers  do,  so  make  sure  to  try  a  couple  of  test  prints.  If  things  aren’t  aligning  quite  right,  experiment  with  the  Scale  to  Fit  Paper  seCng.  It’s  located  in  the  Print  dialog  –  just  click  Full  Page  Slides  to  get  to  it.

And  did  you  no%ce  we  made  fold  marks  for  you?  They  are  really  light,  but  if  you  don’t  like  them  showing  on  your  brochure,  click  View,  Slide  Master,  and  delete  them  before  you  print.

Customizing  the  Content: The  placeholders  in  this  brochure  are  formaNed  for  you.  If  you  want  to  add  or  remove  bullet  points  from  text,  just  click  the  Bullets  buNon  on  the  Home  tab.

If  you  need  more  placeholders  for  %tles,  sub%tles  or  body  text,  just  make  a  copy  of  what  you  need  and  drag  it  into  place.  PowerPoint’s  Smart  Guides  will  help  you  align  it  with  everything  else.

Want  to  use  your  own  pictures  instead  of  ours?  No  problem!  Just  click  a  picture,  press  the  Delete  key,  then  click  the  icon  to  add  your  picture.

If  you  replace  a  photo  with  your  own  and  it’s  not  a  flawless  fit  for  the  space,  you  can  crop  it  to  fit  in  almost  no  %me.  Just  select  the  picture  and  then,  on  the  Picture  tools  Format  tab,  in  the  Size  group,  click  Crop.

Imaging  and  Visualization  Group  

http://ncifrederick.cancer.gov/isp/abcc  

[email protected]  301-846-7366

•  3D  Biomedical  Visualization  

•  Quantitative  Image  Analysis  

•  Information  Visualization  

•  Image  Archive    

•  Nano-­‐Structural  Support  

IVG

u Works with NCI/FNLCR imaging facilities and investigators

u Gathers user requirement from

domain exports in imaging facilities

u Collaborates with external imaging communities

u Adopts new technologies in image analysis and visualization

u Performs technology development

u Builds workflows to increase image analysis throughput

u Develop and maintenances computing infrastructure for image analysis – including common software tool sets, thin clients, and servers

The  Team   ABCC  

ISP,  FNLCR  

Advanced  Biomedical  Computing  Center    

Information  Systems  Program    

Frederick  National  Laboratory    for  Cancer  Research  

Page 2: TheTeam5 ABCC!€¦ · Prinng: Your,printer,might,not,print,the, same,way,our,printers,do,,so, make,sure,to,try,a,couple,of,test, prints.Ifthingsaren’taligning quite,right,,experiment

Prin%ng: Your  printer  might  not  print  the  same  way  our  printers  do,  so  make  sure  to  try  a  couple  of  test  prints.  If  things  aren’t  aligning  quite  right,  experiment  with  the  Scale  to  Fit  Paper  seCng.  It’s  located  in  the  Print  dialog  –  just  click  Full  Page  Slides  to  get  to  it.

And  did  you  no%ce  we  made  fold  marks  for  you?  They  are  really  light,  but  if  you  don’t  like  them  showing  on  your  brochure,  click  View,  Slide  Master,  and  delete  them  before  you  print.

Customizing  the  Content: The  placeholders  in  this  brochure  are  formaNed  for  you.  If  you  want  to  add  or  remove  bullet  points  from  text,  just  click  the  Bullets  buNon  on  the  Home  tab.

If  you  need  more  placeholders  for  %tles,  sub%tles  or  body  text,  just  make  a  copy  of  what  you  need  and  drag  it  into  place.  PowerPoint’s  Smart  Guides  will  help  you  align  it  with  everything  else.

Want  to  use  your  own  pictures  instead  of  ours?  No  problem!  Just  click  a  picture,  press  the  Delete  key,  then  click  the  icon  to  add  your  picture.

If  you  replace  a  photo  with  your  own  and  it’s  not  a  flawless  fit  for  the  space,  you  can  crop  it  to  fit  in  almost  no  %me.  Just  select  the  picture  and  then,  on  the  Picture  tools  Format  tab,  in  the  Size  group,  click  Crop.

Integrated  Visualization,  Analysis,  and  

Navigation(IVAaN)  

Analyzing  TCGA  Meta-­‐data  

Information  Visualization  and  Visual  Analytics  in  Biomedical  Research  

IVG  focuses  on  providing  efficient  collaborative  open  access  to  large-­‐scale  heterogeneous  biomedical  datasets.        Utilizing  Html  5,  d3.js,  and  other  web-­‐based  technologies,  IVG  develops  web  applications  allowing  users  to  browse,  select,  compare,  and  visualize  biomedical  data  stored  on  remove  server.    Based  on  NoSQL  database  MongoDB,  IVG  develops  workflows  and  web  applications  allowing  user  to  save  analysis  process  for  future  review  and/or  collaborative  sharing  with  other  colleagues.    By  continuously  exploring  new  technologies,  IVG  is  able  to  quickly  prototype  workflows  and  web  applications  in  order  to  meet  the  evolving  and  changing  biomedical  data  analysis  needs.    

In  recent  collaboration  with  the  Optical  Microscopy  Analysis  Laboratory,  the  IVG  utilized  developed  IVAaN  framework  to  convert  a  35GB  heterogeneous  microscopy  experiment  dataset  to  an  interactive  web  application  for  effective  navigation,  visualization  and  analysis.  

The  image  above  shows  a  snapshot  of  the  dataset.  The  dataset  includes  approximately  74,000  files  and  folders,  including  images  in  different  formats,  spread  sheets,  text  files,  and  other  binary  format  data  files.  Manual  navigation  in  such  complex  dataset  is  difficult  due  to  the  tedious  file  browsing  and  crowded  display  space  showing  data  files  in  a  traditional  windows  based  way.  

Snapshot  of  the  35GB  dataset  

Integrating  NoSQL  database  MongoDB,  d3.js  JavaScript  visualization  library,  and  other  open  source  software  libraries  and  tools,  the  IVG  created  an  interactive  web  application  for  quick  data  navigation,  search,  and  multi-­‐dimensional  data  analysis.  Snapshot  of  the  app  is  shown  to  the  right.  

Snapshot  of  the  IVG  developed  web  app  

The  hierarchical  data  set  visualization  and  analysis  workflow  in  the  IVG  IVAaN  framework  allows  user  to  view  ~8000  TCGA  XML  files  in  a  tree  structure.    Users  can  select  subset  to  create  a  keyword  view  and  be  able  to  see  unique  values  connected  to  the  selected  keyword.  Then  a  subset  of  XML  files  can  be  selected  from  the  selected  keyword-­‐value  pair  for  quick  narrow  down  the  scope  for  examination.  User  selections  of  XML  files,  keyword,  and  values  can  be  saved  for  future  view.    

The  IVG  develops  Integrated  Visualization,  Analysis,  and  Navigation  (IVAaN)  framework  to  provide  support  in  information  visualization  and  visual  analytics  for  biomedical  research.