throat cancer
DESCRIPTION
Karjan Basumatary Has Presented this PPT & has been awarded as a best award in class participation at International School of Information Management, University of Mysore,[email protected]TRANSCRIPT
Throat cancer Presented By Karjan Basumatary M.tech (IS&M)@ISiMUniversity Of Mysore-570006
04/09/231throat cancer Bio-Informatics
AimThe main aim is a treatment to remove
completely the cancer & preventing the spread of the cancer to other parts of the body.
04/09/232throat cancer Bio-Informatics
What is throat Cancer??Throat cancer is a condition where cancer affects the
vocal cords, voice box (larynx), or other areas of the throat.
04/09/233throat cancer Bio-Informatics
Types of throat cancer
Oropharyngeal cancer : The part of throat that is right behind your mouth.
larynx or Laryngeal CancerGlottic cancer begins in the vocal cords or Voice
boxNasopharyngeal Cancer: The part of throat just
behind your nose.Hypopharyngeal Cancer: The lower part of throat,
just above your esophagus and windpipe.
04/09/234throat cancer Bio-Informatics
Top: Diagram of a LarynxRight: Larynx with cancer
•The larynx is also referred to as the voice box. It contains vocal cords to help assist with speech
04/09/235throat cancer Bio-Informatics
Sign & symptomsAbnormal (high-pitched) breathing soundsHoarseness that does not resolve in 1 to 2 weeksSore throat that does not resolve in 1 to 2 weeks,
even with antibioticsCoughCoughing up bloodDifficulty swallowingNeck painSwelling in the neckUnintentional weight loss
04/09/236throat cancer Bio-Informatics
Throat cancer causes Major causes of Throat Cancer..when cells in our throat develop genetic mutations.SmokingAlcoholOccupational Exposures Genes from Ancestors
04/09/237throat cancer Bio-Informatics
Stages of Throat CancerStage 1Stage 2Stage 3Stage 4
04/09/238throat cancer Bio-Informatics
Types of treatmentsurgery.radiation treatmentchemotherapy
04/09/239throat cancer Bio-Informatics
Side effects for treatment of throat cancerTender mouth soresHair lossDry mouth (xerostomia)Sensitive tongueBitter taste in mouthNumbness in parts of the neck and throatLoss of appetiteNauseaFatigueDifficulty swallowing (dysphagia)Speech problemsWeak or stiff shoulder and neck
04/09/2310throat cancer Bio-Informatics
Risk Factors of throat cancerDamage of DNA cells in mouth & throatHPV(Human Papillomavirus)Throat cancers can be cured in 90% of patients if
detected early
04/09/2311throat cancer Bio-Informatics
Newly Discovered Cancer geneAdenoid Cystic Carcinoma (neck & head)
what is known as a fusion gene, created when two healthy genes join together as a result of a chromosome change.
04/09/2312throat cancer Bio-Informatics
Histopathological image of adenoid cystic carcinoma of the salivary gland. Haematoxylin & eosin stain.
Problem Statement
04/09/23throat cancer Bio-Informatics13
Detection of fusion gene through DNA sequence analysis.
Methodology
04/09/23throat cancer Bio-Informatics14
Multiple sequence analysisIdentifying the throat fusion genes in the genome
Gene therapy
04/09/23throat cancer Bio-Informatics15
Gene therapy is an experimental treatment that involves introducing genetic material (DNA or RNA) into a person's cells to fight disease.
Approaches
04/09/23throat cancer Bio-Informatics16
Replace missing or altered genes with healthy genes. Researchers introduce “suicide genes” into a
patient's cancer cells. Will focused on the use of gene therapy to prevent
cancer cells from developing new blood vessels.P53 ‘Genome Guardian’: Gene therapy for cancer to
repair the malfunctioning of this natural genetic guardian.
Genes are not directly inserted into the patient's body, but uses viruses for that purpose. Such as retroviruses, adenoviruses, herpes viruses, lentiviruses and poxviruses.
Informatics
04/09/23throat cancer Bio-Informatics17
A 24 hours On line systems.Inserts, store, manage & monitor the health
condition of patients for present & previous.Automatic alarm systems for emergency.System having Own X-Ray Machines.On line treatment systems with the other
countries doctor.
Thank you
04/09/23throat cancer Bio-Informatics18