tilda and the hrb professor rose anne kenny trinity college mercers institute st james hospital
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Trinity College Dublin, The University of Dublin
Trinity EngAGE Centre for Research in Ageing
International Impact (2009-2013)
• Geriatrics & Gerontology: % of Papers in Top 1% - InternationalSource/s: InCites/Web of Science/Scopus
Trinity College Dublin, The University of Dublin
InnoLife Consortium- Health and Ageing European Institute of Technology KIC
EIT Budget €2.7B (2015-2020)
TCDImperialOxfordCambridgeNewcastleKarlinski
New knowledgePopulation research
Clinical trialsPolicy needsPolicy impact
Training
www.tilda.iewww.tilda.ie
Creating Infrastructure
Biobanking,
Population sample,
Multidisciplinary- HUB
Training Education –community
Soft ware
2010, 2012, 2014, 2016. refresh.... www.tilda.iewww.tilda.ie
GenesGenesGenesGenes
NutritionNutritionNutritionNutrition
Family Family networksnetworksFamily Family
networksnetworks
Social Social participationparticipation
Social Social participationparticipation
EducationEducationEducationEducation
Household Household StructureStructure
Household Household StructureStructure
Marital Marital StatusStatus
Marital Marital StatusStatus
Work &Work &RetirementRetirement
Work &Work &RetirementRetirement
Income Income & assets& assetsIncome Income & assets& assets
HealthHealthHealthHealth
Experience Experience of Ageingof Ageing
Experience Experience of Ageingof Ageing
Mental Mental healthhealth
Mental Mental healthhealth
www.tilda.iewww.tilda.ie
2014•HRA: Inequalities in Access to GP Care in Ireland: An Analysis using Longitudinal Data €329,988 (€150,424 to TILDA) •HRA: Hypotension, vasoreactivity and white matter intensities in the ageing brain: The Irish Longitudinal Study on Ageing (TILDA) - €330,000•HPF Research Training Fellowships for Healthcare Professionals (2014) - €244,206
2013•HRA: Targeted actions to identify novel inflammatory and immunological factors associated with predisposition to AMD in the TILDA population cohort (2013) [Overall budget €329,987]
2012•HRB ICE: Interdisciplinary Capacity Enhancement (ICE) Awards 2012- Effecting change in cardiovascular health in older Irish Adults (2012) - €589,327•HRA: Project SADD: Socioeconomic position, anxiety, depression and diabetes in the ageing population in Ireland (2012)- €331,000
2011•HRB ICE: Interdisciplinary Capacity Enhancement (ICE) Awards 2011- Building research and implementation capacity in the Irish Longitudinal Study on Ageing (TILDA): health inequalities, mental health and opportunities to influence health and social care policies - €794,681• HRA: Frailty and Cognitive impairment in the older population (2011) - €297,750
HRB PhD Scholars programme
6 Ph.D. Scholars (2008-2010)
15 Ph.D. Scholars 2010-
TILDA Core – 10 Ph.D 2009- 2013 4 Ph.D. present
Heart Rate Recovery and Mortality6
78
910
11
12
13
14
HR
Diffe
ren
ce fro
m B
ase
line
(B
PM
)
10 20 30 40 50 60 70 80 90 100 110
Recovery Time (secs)
Alive (4yr follow-up) Deceased (4yr follow-up)
Hypertension prevalence over 50 years (TILDA wave 1)
.
Awareness in hypertensives
Blood pressure controlled to SBP<140 mmHg and DBP<90mmHg
52%52%Treatment in hypertensives BP control in the treated
On antihypertensive medication (ATC codes CO2, CO3, CO7, CO8, CO9)
59%59%
Awareness defined as a self-report of ever having a doctor’s diagnosis of hypertension
55%55%
64% 64% of those aged 50yrs and older were hypertensive
Statin use in groups at high risk of CVD (50-64 years, W1)
Statin use for secondary prevention (those with existing CVD) is lower than expected given the strength of evidence for the use of statins in this group
– known CVD 68.8% using statins– multiple CVD events 78.6% using statins
.
Statin use in groups at high risk of CVD (50-64 years, W1)
Statin use for secondary prevention (those with existing CVD) is lower than expected given the strength of evidence for the use of statins in this group
– known CVD 68.8% using statins– multiple CVD events 78.6% using statins
Statin use for primary prevention in those at high risk of CVD is also low
– Known diabetics 57.4% using statins– High or very high absolute risk group 19.0% using statins
.
Project SADD: Socioeconomic position, anxiety, depression and diabetes in the ageing population
−Diabetes affects 8.3% of adults aged 50+ in Ireland, rising to 12% in those aged 75+
−primary level or no education are 60% more likely to have diagnosed diabetes
−Cross-sectionally, diabetes is not independently associated with depression or anxiety
−those with diagnosed diabetes at Wave 1 reported a Major Depressive Disorder (11.9% vs. 7.4%) or Generalized Anxiety Disorder (12.8% vs. 7.5%) after a two year follow-up