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Simplifying Progress Investors Presentation Full-Year 2020 Results

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Page 1: Titelfolie mit langer Überschrift, zwei- oder mehrzeilig ... · High exposure to attractive biopharma and life science industry €412m ~ €2.2bn Sales with life science customers

Simplifying Progress

Investors PresentationFull-Year 2020 Results

Page 2: Titelfolie mit langer Überschrift, zwei- oder mehrzeilig ... · High exposure to attractive biopharma and life science industry €412m ~ €2.2bn Sales with life science customers

This presentation contains statements concerning the future performance of the Sartorius Group. These statements are based on assumptions and estimates. Although we are convinced that these forward-looking statements are realistic, we cannot guarantee that they will actually materialize. This is because our assumptions harbor risks and uncertainties that could lead to actual results diverging substantially from the expected ones. It is not planned to update our forward-looking statements.

Throughout this presentation, differences may be apparent as a result of rounding during addition.

Disclaimer

2

Page 3: Titelfolie mit langer Überschrift, zwei- oder mehrzeilig ... · High exposure to attractive biopharma and life science industry €412m ~ €2.2bn Sales with life science customers

Agenda

3

Overview | Strategy

Bioprocess Solutions Division

Lab Products & Services Division

FY 2020 Results | FY 2021 Guidance

Page 4: Titelfolie mit langer Überschrift, zwei- oder mehrzeilig ... · High exposure to attractive biopharma and life science industry €412m ~ €2.2bn Sales with life science customers

Partner of biopharmaceutical research and industry

4 Overview | Strategy

We empower scientists and engineers to simplify and accelerate progress in life science and bioprocessing, enabling the development of new and better therapies and more affordable medicine.

The United Nations’ sustainability goal ‘Good Health and Well-Being’ is thus an integral part of our core business.

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1 For continued operations, in constant currencies 2 Excluding extraordinary items

5

~€2.3bn Sales revenue 2020

~16.0%Sales CAGR1 2015-2020

29.6%EBITDA margin2 2020

~ 11,000Employees

60+Locations worldwide, headquartered in Göttingen, Germany

High exposure to attractive biopharma and life science industry

€412m

~ €2.3bn

Sales with life science customers

Group sales revenue

20202000

~85%

Overview | Strategy

Sartorius at a glance

~35%

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6

Strategic focus of both divisions on the biopharma value chain

Overview | Strategy

Lab Products & Services Division

Quality | Testing | Validation

Upstream & downstream production

Molecule development

Cell line and process development

Bioprocess Solutions Division

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~10% CAGR for biopharmamarket 2020–2025

7

Attractive market environment with strong growth opportunities

Overview | Strategy

Favorabledemographics

9bn people by 2050; >2bn 60 yrs or older

Rise ofbiosimilars

~30% CAGR for biosimilar sales 2020–2025

Strong R&D pipeline; advances in gene and cell therapy

>40% share of biologics in pharma R&D pipeline

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19.7 20.1 20.5 21.023.6

25.0 25.1 25.927.1

29.6

17.5

19.5

21.5

23.5

25.5

27.5

29.5

31.5

33.5

35.5

37.5

39.5

300

500

700

900

1100

1300

1500

1700

1900

2100

2300

2500

2011 2012 2013 2014 2015 2016 2017 2018 2019 2020

+12.6%+16.0%

+18.2% +9.3%

+8.8%

~€2.34bn

~€650m

+13.6%

+13.2%

8

Sales CAGR ~+15%+14.8%EBITDA1 margin +9.9pp

Sales, growth and CAGR 2011-20 for continued operations, in constant currencies 1 Excluding extraordinary items

Sales revenue EBITDA1 margin in % Intec Division; divested in 2|2015

Overview | Strategy

Sales revenue has doubled over the last 5 years

+30.2%

~€1.12bn

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9

CAGR for continued operations

53%

25%

22%

2011

~€650m

40%

35%

25%

2019

~€2.3bn

22%

50%

28%

2019

~€250bnCAGR

~+17%

~+20%

~+12%

Asia | Pacific

Americas

EMEA

Global biopharma market 2020 Sales by region 2011 Sales by region 2020

Overview | Strategy

Regional balance better reflecting end-markets

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8.8 7.7 9.1 10.1 11.7 14.9 15.2 12.3 10.315.0

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021

Expansion of fluid management and cell culture media production capacities

Major projects

Regular expansion

Capitalized R&D

Maintenance ~3%

~2%

~3%

~X%

1

1 Incl. discontinued operation 2 Based on 2021 guidance

1

CAPEX ratioin %

CAPEX composition 2021

2

10

Expansion of bioreactor production capacities

Overview | Strategy

Preparing infrastructure for further organic growth

Accelerated and extended global capacity expansion, especially in BPS, due to growth expectations

Expansion of membrane and filter production capacities

~

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Life Science assets from Danaher

11

Acquisition criteria

Portfolio: Complementary products or technologiesMarket position: Either among the Top 3 or unique selling pointIntegration: Management capacity; cultural fitPrice: Fair valuation; reach Sartorius‘ profitability level in 2-3 years

Overview | Strategy

M&A strategy – adding innovation, enhancing focus

2015 2016 2017 2018

Intellicyt ViroCytEssen

BioScience

CellcaBioOutsource

kSep

2019

Umetrics

2021

DivestmentIntec Division

WaterSepBIA Separations

Biological Industries

2020

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12

Recent acquisitions strengthen portfolio…

May 2020 Date of consolidation

~$170m Sales revenue in 2019

+ 300 Employees

~$825m Purchase price

Acquisition of selected life science assets from Danaher

Assets include bioanalytical tools for LPS; upstream and downstream technologies for BPS

Overview | Strategy

Acquisition of BIA Separations

Technology for purification in advanced therapy processes

Consolidated in BPS division

Nov. 2020 Date of consolidation

~€25m Sales revenue in 2020e

+ 120 Employees

€360mn Purchase price1

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13

…especially in downstream

Dec. 2020

~$2.5m + 15

Acquisition of WaterSep BioSeparations

Innovative hollow fiber crossflow filtration units

Consolidated in BPS division

Purchase price $27mn plus earn-out

Sales revenue in 2020e

Employees Date of consolidation

Agreement to acquire chromatography processequipment division from Novasep

Resin-based batch and intensified chromatography systems

Consolidated in BPS division

Purchase price not disclosed

H1 2021~€37m + 100

Sales revenue in 2020e

Employees Closing expected

Overview | Strategy

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BPS Sartorius GroupLPS

~€3.8bn previously ~€2.8bn

~34%previously ~30%

14

2025 targets are based on 2020 currency exchange rates; EBITDA excluding extraordinary items

Updated 2025 ambition

~€1.2bn unchanged

€5bnpreviously ~€4bn

~25%unchanged

~32%previously ~28%

Sales revenue

EBITDA margin

Overview | Strategy

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Initial 2025 group sales revenue targets were based on an estimated 2020 group revenue of €2bn, based on the mid-term guidance of 2012

Expectation was to double the revenue target to €4bn within 5 years

Actual 2020 Group revenue was approx. €2.3bn; with the overachievement being mainly driven by BPS

The new mid-term target of €5bn in revenue reflects both the elevated baseline and future growth prospects

Continued strategy is to achieve the targets primarily through organic growth; acquisition to contribute underproportionally

The increase in the profitability outlook is due to economies of scale and also reflects the assumption of acquisitions to beinitially dilutive

15

2025 ambition – increased baseline and organic growth

Overview | Strategy

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Our products are widely used in the development and production of biologics against COVID-19

The majority work with Sartorius products

Overview | Strategy

180+ companies developing corona vaccines

Pandemic effects in the divisions in 2020

BPS with pandemic-related net effect of~12pp on sales and ~17pp on order intakegrowth; consisting of investments in vaccineand therapeutic research and manufacturing, also inventory build-up

LPS with -1pp net effect on sales growth withnegative impact from closure of laboratoriesin China and the U.S. in H1 and positive demand for products involved in testing forcoronavirus

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Agenda

17

Overview | Strategy

Bioprocess Solutions Division

Lab Products & Services Division

FY 2020 Results | FY 2021 Guidance

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809.2

1,782.6

26.5

32.3

23252729313335

300500700900

1100130015001700

18

Global footprintDivision sales by region

Based on FY 2020 figures; sales CAGR in constant currencies, including non-organic growth 1 Excluding extraordinary items

Asia|Pacific~24%

Americas~37%

EMEA~39%

Single-use products ~75%

Equipment ~25%

Total solution provider for biomanufacturing

Bioprocess Solutions

Snapshot of the Bioprocess Solutions Division

High share of recurring revenuesDivision sales by category

Track record of dynamic growthSales revenue, € in millions; EBITDA margin1 in %

2015 2020

+17.6%CAGR

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19

Generating revenue throughout the lifecycle of a biopharma drug

Stage

Scale

Wide product range of equipment and consumables for all stages (from pre-commercial to large-scale manufacturing); optimal scalability

Engineering support with excellent application knowhow and understanding of the entire bio-production process

Production process of each individual drug is subject to validation by health authorities (e.g. FDA, EMA) and part of the drug approval

Bioprocess Solutions

Process development Proof of concept - pilot Large

Preclinical (1 year)

Clinical(4-7 years)

Commercial(15+ years)

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Virus clearance & filtration

Chroma-tography

Cryo-preservation

Concen-tration

Sterile filtration

Culture mediapreparation

FermentationSeedcultivation

Scale-up

Clarification & centrifugation

Bioprocess Solutions

Covering most steps of the biopharmaceutical manufacturing process

UPSTREAM

DOWNSTREAM

Finalfilling

Differentiated by the rangeand completeness of the portfolio

Excellent positioning in key single-use technologies

Internationally recognized supplier enabling innovation in bioprocessing through own R&D and partnerships

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21 Bioprocess Solutions

Integrated services and technologies for all types of biopharmaceuticals

Vaccines

Engineered tissue

Bioconjugates

mAbs Regenerative medicine

~ 95% of BPS revenue generated with bio/pharma customers

Antibodies are most relevant; strong position in vaccines as well

BPS provides solutions for the development and production of all biotechnologically derived drugs and cell derivatives

These also include new modalities such as cell and gene therapies and viral vectors

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Sartorius Merck | Millipore Pall Cytiva1

ThermoFisher

Top 3 Players

Filtration1. Merck | Millipore2. Danaher | Pall3. Sartorius

Fluid Management

1. Sartorius2. Thermo Fisher3. Merck | Millipore

Fermentation1. Sartorius2. Thermo Fisher3. Danaher | Cytiva

Purification1. Danaher | Cytiva2. Merck | Millipore3. Sartorius

Cell Culture Media

1. Thermo Fisher2. Merck | Millipore3. Danaher | Cytiva

22 Bioprocess Solutions

Competitive portfolio across our relevant end-markets

Pie charts indicate completeness of product offering1 Formerly GE Biopharma

Danaher

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23

Acquisition of selected Danaher life science assets strengthens chromatography portfolio Assets include chromatography systems, columns and resins; indispensable for the purification of biologics

Well-established technologies and innovative solutions in the high-growth areas of single-use and intensified purification

Complement existing membrane-based solutions enabling Sartorius to support purification strategies at all scales

Systems ResinsColumns

Bioprocess Solutions

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24

Recent acquisitions also strengthen offering in other key technologies

Cell culture media2

Extensive portfolio of cell culture media with focus on advanced therapies (e.g. cell and gene therapies)

Gives Sartorius own production and development capabilities

Access to customers in an increasingly important and fast-growing market

Microcarriers1

Tangential flow filtration systems1

To support growth of adherent cell cultures

Closing last gaps in TFF portfolio

Highly competitive product portfolio

1 Part of the selected life since assets acquired from Danaher in Q1 2020; 2 Product portfolio of Biological Industries acquired in Q4 2019

Bioprocess Solutions

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25

BIA Separations - Bioprocessing innovator, addressing bottlenecks in advanced therapies

Ajdovščina, Slovenia

~120 employees

Quadrupling production capacity till end 2021

Monolithic columns

Portfolio

Pre-packed monolithic columns optimized for purification in advanced therapy processes (e.g. viruses, plasmids, exosomes)

Provides significantly higher yield by avoiding shearing effects which occur in traditional purification processes, e.g. in chromatography

Positioning

Monoliths already used in production of first commercialized advanced therapeutics

Strong presence in (pre-) clinical projects

Bioprocess Solutions

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26

WaterSep BioSeparations – Further broadening our filtration portfolio

Marlborough, USA

~15 employees

R&D and production of membranes and cartridges

Hollow fiber cartridges

Portfolio

Hollow-fiber membrane devices and pre-sterilized assemblies for crossflow filtration applications in upstream and downstream

Addresses customer needs for cost- and time-saving solutions

Stategic fit

Complements offering for cell and gene therapy applications, cell harvesting and various solutions for intensified bioprocessing

Bioprocess Solutions

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27

Biologics market growth forecast

U.S.~167

China~67~€365bn

Europe~58

ROW~72

U.S.~119

China~38 ~€250bn

ROW~47

Europe~46

~+15% China

~+9% U.S.

~+6% Europe

Bioprocess Solutions

U.S. remains most important market; China with highest growth rates

2020 2024

CAGR

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Huge market potential due to population size and growing average demand

Biopharma market development priority for China

Currently a CDMO/biosimilar-driven market; with an increasing number of originators across all biopharma modalities

Sartorius with long-standing local presence (production in Shanghai and Beijing); further expansion planned

28 Bioprocess Solutions

Dynamic increase in new biopharma companies in China in the past years

2650

79

141

0

60

120

180

240

300

Before 1990 1990-2000 2000-2010 2010-2020

111

179

269228

0

60

120

180

240

300

Before 1990 1990-2000 2000-2010 2010-2020

3155 69

39

0

60

120

180

240

300

Before 1990 1990-2000 2000-2010 2010-2020

China U.S. Europe

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29

0 03 1

7

22 2015 16

2012 2013 2014 2015 2016 2017 2018 2019 2020

Growing number of biosimilar approvalsE.U. and U.S.

Biosimilars will outperform the biologics market€ in billions

~235.5 ~323.5

2020 2024

~14.5~41.5

BiosimilarsOther biologics

~+30%CAGR

Major blockbuster biologics are going off-patent

Time-to-market is key as only the first providers are most likely profitable

Several approvals in Asia and Europe; U.S. at the beginning

For now, relatively small market but with strong growth

Single-use is the preferred platform for biosimilars

Bioprocess Solutions

Biosimilars: Strong growth, big opportunities

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30

-25-35%

-55-65%-65-75%

Construction cost Energy cost Water cost

-30-50%

Time-to-market

ReferenceSingle-use

Bioprocess Solutions

Pioneer and leader in the growing single-use technology market

Single-use market penetration expected to increase from ~35% to ~75%Single-use products offer advantages over conventional stainless-steel devices

Capex|Opex reduction over entire lifecycle

Reduced risk of cross-contamination

Higher flexibility; advantageous for biosimilars

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Construction of stainless-steel based facilities takes longer and is more complex compared to single-use

Therefore, investment in stainless-steel facilities has to start in early clinical phase II

The construction of single-use facilities may start in clinical phase III, reducing investment risks of our clients

Bioprocess Solutions

Single-use allows manufacturers to mitigate investment risks

Clinical Phase IIClinical Phase I Clinical Phase III

Probability that candidate advances to next stage

Probability of approval

~ 60%

~ 10%

~ 30%

~ 15 %

~ 50%

~ 50%

Data based on: Wong et al. (2018): Estimation of clinical trial success rates and related parameters

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32 Bioprocess Solutions

Analytical technologies to improve process economics and safety

Bioprocess sensors, analyzers and software

Collect, monitor and control quality-critical parameters

Analyze data to obtain a better process understanding

Use knowledge for process development, optimization and automation

Allows customers to increase time-to-market, to reduce COGS, to improve process robustness and product quality

Intention to upgrade Umetrics software suite with advanced analytics technologies such as AI and machine learning

Data analytics just at the beginning in biomanufacturing with high potential

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High innovation dynamics in Biopharma

Development of new drugs and vaccines must be accelerated, e.g. through more automation

Increased efficiency possible in the production of 'classic' biopharmaceuticals and biosimilars

New tools and methods required e.g. for novel cell and gene therapies

Future drug manufacturing is more automated, intensified and scalable

Bioprocess Solutions

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More than half of 2020 BPS sales were generated with the Top 50 customers

No individual customer accounts for more than 5% of BPS sales revenue

0100200300400500

Sales to Top 50 customersin 2020, € in millions

Top 10 11 to 20 21 to 30 31 to 40 41 to 50

Cumulative share

~28%~40% ~48% ~53% ~57%

Limited dependence on individual accountsLong-term business relationships with leading global (bio-) pharma companies

Bioprocess Solutions

Limited dependence on individual accounts

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~+18% Organic CAGR1

35

1 CAGR 2014 to 2020, excluding FX effects and acquisitions

2014 2015 2016 2017 2018 2019 2020

Pharmamarket

Biopharmamarket

Single-usepenetration

Market share gains

CAGR 3-6%

CAGR ~10%

Double-digit growth

Esp. in North America

Bioprocess Solutions

Four strong pillars drive above-average growth

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Agenda

36

Overview | Strategy

Bioprocess Solutions Division

Lab Products & Services Division

FY 2020 Results | FY 2021 Guidance

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325.3

553.0

16.0

21.0

13

15

17

19

21

23

25

27

29

100150

200250300350400450500550600

2016 2020

222.0

305.5

16.716.0

14

16

18

20

22

24

26

28

30

100150

200250300350400450500550600

2011 2015

37

Global footprintDivision sales by region

Based on FY 2019 figures; sales growth and CAGR in constant currencies, including acquisitions 1 Excluding extraordinary items

Premium vendor for laboratories

Asia|Pacific~28%Americas

~29%

EMEA ~43%

Build-up of bioanalytics portfolio

since 2016

CAGR +7.0%

CAGR +14.9%

Division in transition to a new growth and profitability profileSales revenue, € in millions; EBITDA margin1 in %

Lab Products & Services

Snapshot of the Lab Products & Services Division

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Portfolio includes lab essentials and bioanalytical instruments; increased focus on life science end-market

Lab balances, pipettes, lab water systems and filtration for bio/pharma QC/QA ~30% share of bioanalytics; used for

analysis of cells or biomolecular interactions in drug and cell line development

Lab balances, pipettes, lab water systems and filtration Addresses QC/QA laboratories in food &

beverage and chemical industry among others

Lab Products & Services

Applied Research sales~50%

Life Science Research sales~50%

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Average global market share of >10%

High gross margins offer potential for economies of scale

Growth potential especially in the U.S. and Asia

Market growth related to R&D spending in the individual end markets

Lab Products & Services

Strong market position in essential laboratory product categories

Lab balances Microb. analysis Lab filtration Pipettes

#2 #2 #3 #4

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Based on data from the Tufts Center for the Study of Drug Development and the Association of the British Pharmaceutical Industry

Lab Products & Services

Bioanalytical tools to address customers pain points

>10 yearsFrom drug discovery to

approval>€2bn

Average costs of developing a successful drug

~10 %Probability of clinical success

(Phase I to approval)

1-2 years1 year 4-7 years4-5 years

Drug discovery Preclinical testing

Clinical trials Drug approval Our approach Facilitate digitalization

and automatization Decrease likelihood

of failure Reduce time and costs in

molecule development; increase time-to-market

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Overview of bioanalytical portfolio

Solutions for cell analysis IncuCyte: Real-time imaging and analysis of living cells

iQue Screener: Rapid, high content analysis of cells, beads and secreted proteins

Solutions for protein analysis Octet: Real-time, label-free measurement of biomolecular

interactions

Lab Products & Services

Competitive environment Beckman Coulter Becton Dickinson Bio-Rad Cytiva Merck PerkinElmer Thermo Fisher ...

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42 Lab Products & Services

Solutions complement each other, optimize successive workflows and have synergies with BPS products

Application example: Molecule development

OctetIdentify high-producing clones in expression library

ambr15 (BPS division)Culture identified clones on small-scale

IncuCyte | iQueScreenerSelection of lead candidates and functional characterization

Application example: Cell line development

iQueScreenerScreening of antibody libraries for target-reactive candidates

OctetMeasure how strong the identified antibodies bind to their target and rank

Octet | iQueScreenerAnalysis and characterization of cell line and antibodies

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~3.5~4.3

~1.3

~1.9

2020 2025

Addressable market of LPS€ in billions

LPS ex bioanalytics

Bioanalytics+3.5%CAGR

+8%CAGR

Different growth rate of bioanalytics due to high exposure to biopharmaceutical R&D

By 2025, two-thirds of the addressable market growth will come from bioanalytics

Thus, growth and profitability profile of LPS is changing over time

Lab Products & Services

Bioanalytics increases addressable market and changes growth profile

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Agenda

44

Overview | Strategy

Bioprocess Solutions Division

Lab Products & Services Division

FY 2020 Results | FY 2021 Guidance

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45

1 Constant currencies 2 Underlying = excluding extraordinary items 3 Underlying EPS = based on net profit after non-controlling interest;adjusted for extraordinary items as well as amortization and based on a normalized financial result and normalized tax rate

Sartorius Group in millions of € unless otherwise specified

2019 2020 in % in % cc1

Sales revenue 1,827.0 2,335.7 +27.8 +30.2

Order intake 1,939.5 2,836.3 +46.2 +49.0

Underlying EBITDA2 495.8 692.2 +39.6

Underlying EBITDA2 margin in % 27.1 29.6 +2.5pp

Underlying EPS3 (ord.) in € 3.06 4.37 +43.0

Underlying EPS3 (pref.) in € 3.07 4.38 +42.9

Acquisitions contribute a good 7pp to sales growth; net effect from pandemic a good 8pp / close to 14pp for order intake

Underlying EBITDA margin driven by economies of scale and underproportionate development of costs in some areas due to pandemic; acquisitions with slightly positive effect; slightly dilutive effect from currencies

Strong profitable growth

FY 2020 Results | FY 2021 Guidance

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46

Americas€ in millions

Asia|Pacific€ in millions

EMEA€ in millions

629.9812,2

2019 2020

+32.8%

463,7588.4

2019 2020

+29.6%

733.4935.1

2019 2020

+28.4%

Americas: BPS benefits from demand in connection with the development of corona vaccines; LPS with larger acquisition impact EMEA: BPS with tailwinds from vaccine developers; solid performance of LPS considering economic challenges Asia|Pacific: BPS with the highest order momentum; LPS demand improved after lockdown lifted in China with catch-up effects

Acc. to customers‘ location; growth in constant currencies

Double-digit sales growth in all geographies

FY 2020 Results | FY 2021 Guidance

Sales by Regionin %

Asia|Pacific~ 25%

Americas~ 35%

EMEA ~ 40%

€2,335.7m

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393.1575.9

2019 2020

29.1% 32.3%

Strong organic growth; pandemic-driven effects presumably around 12pp (majority of that from demand related to coronavirus vaccines and therapeutics but also related to inventory build-up), acquisitions accounted for close to 5pp of growth

Pandemic-related effects estimated at around 17pp of order intake growth Underlying EBITDA margin rose due to economies of scale and reduced costs in some areas due to pandemic; slight FX dilution

Order Intake€ in millions

47

Sales Revenue€ in millions

Underlying EBITDA & Margin € in millions

1,457.6

2,238.1

2019 2020

1,350.51,782.6

2019 2020

+56.4% cc+53.5%

+46.5%+ 34.4% cc

+32.0%

1 1 1

1 2019 figures reported: Order intake €1,479.3m, sales €1,372.1m, underlying EBITDA €406.8m

BPS: Dynamic growth across all product categories and regions

FY 2020 Results | FY 2021 Guidance

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Order Intake€ in millions

48

Sales Revenue€ in millions

Underlying EBITDA & Margin € in millions

In particular, high demand for products used in the context of coronavirus testing Acquisitions contribute around 15pp to sales growth; net effect from pandemic approx. -1pp Underlying EBITDA margin influenced by lower capacity utilization due to pandemic; acquisitions accretive by a good 2pp

102.7 116.3

2019 2020

481.9 598.2

2019 2020

476.5 553.0

2019 2020

21.6% 21.0%

+26.4% cc +24.1%

+18.1% cc +16.1% +13.2%

1 1 1

LPS: Rebound and catch-up effects after challenging first half

1 2019 figures reported: Order intake €460.3m, sales €454.9m, underlying EBITDA €89.0m

FY 2020 Results | FY 2021 Guidance

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2019 numbers partly adjusted due to final PPA of BI 1 Underlying net profit = net profit adjusted for extraordinary items, amortization and based on a normalized financial result and normalized tax rate2 After non-controlling interest 3 Net cash flow from investing activities and acquisitions

Sartorius Group in millions of € unless otherwise specified

2019 2020 in %

Underlying EBITDA 495.8 692.2 +39.6

Extraordinary items -28.5 -57.0 n.m.

Financial result -32.5 -9.4 n.m.

Underlying net profit1,2 209.4 299.3 +42.9

Reported net profit2 156.7 226.3 +44.4

Operating cash flow 377.2 519.7 +37.8

Investing cash flow3 -268.7 -1,278.7 n.m.

CAPEX ratio (in %) 12.3 10.3 -2.0pp

Operating cash flow increases significantly

FY 2020 Results | FY 2021 Guidance

Net operating cash flow mostly driven by higher earnings and factoring program (~€89m)

Extraordinary items influenced primarily by M&A

Financial result includes the valuation effect related to the earn-out from the acquisition of BIA Separations

Tax rate at 28.0%; excluding earn-out effect tax rate would be 30.2%

Investing cash flow driven by acquisitions

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Key Financial Indicators

Sartorius GroupDec. 31,

2019Dec. 31,

2020

Equity ratio in % 38.1 29.9

Net debt in millions of € 1,014.0 1,883.6

Net debt | underlyingEBITDA1 2.0 2.6 Q1-Q4

2014Q1-Q42015

Q1-Q42016

Q1-Q42017

Q1-Q42018

Q1-Q42019

0.0

1.0

2.0

3.0

4.0

0

500

1,000

1,500

2,000

Net debt in millions of € (lhs) Net debt to underlying EBITDA (rhs)

Net Debt and Net Debt to Underlying EBITDA

Financial indicators remain on very solid level

Q1-Q42020

Equity ratio influenced by increase in balance sheet sum due to the recent acquisitions and higher cash position

1 Includes underlying pro forma EBITDA of acquisitions completed in 2020

FY 2020 Results | FY 2021 Guidance

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Growth rates expected to be significantly pronounced in H1 due to last years acquisition and strong order book

In 2021, acquisitions projected with no significant profitability effect on the Group and BPS, plus ~0.5pp for LPS

CAPEX ratio ~15% (FY 2020: 10.3%); accelerate and extend capacity expansion especially in BPS due to growth expectations

Net debt to underlying EBITDA is projected at slightly below 2.5 (2020: 2.6)

51

1 In constant currencies

2020 2021 Guidance 1

Sales Revenue Growth

Underlying EBITDA Margin

Sales Revenue Growth

Underlying EBITDA Margin

Sartorius Group +30.2% 29.6% ~ 19% - 25% ~ 30.5%- growth by acquisitions | Corona demand good 7pp | good 8pp ~5.5pp | up to 6pp

Bioprocess Solutions +34.4% 32.3% ~ 22% - 28% ~ 33.0%- growth by acquisitions | Corona demand close to 5pp | ~12pp ~6pp | up to 8pp

Lab Products & Services +18.1% 21.0% ~ 10% - 16% ~ 23.0%- growth by acquisitions | Corona demand ~15pp | -1pp ~5pp | no net impact

Strong outlook for 2021, uncertainties remain high

FY 2020 Results | FY 2021 Guidance

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Appendix

52

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To Sartorius, sustainability means operating responsibly over the long term – with respect to business partners, employees and society as well as to natural resources. Learn more about our commitment:

Please click below for further financial information:

Annual Report 2020

Earnings Release 9M 2020

Half-Year Report H1 2020

Earnings Release Q1 2020

53

Corporate responsibility & further financial information

Appendix

SRI Presentation

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High entry barriers, low price-sensitivity and consolidated

competitive landscape

Biopharma market fueled by long-term

growth drivers

Favorable market positions in key technologies and high brand awareness

Global presence with strong base in

growth regions

Diversified revenue base and high share of recurring

revenues provide low volatility

Proven growth track record: Sales CAGR of ~14%

over the last five years

Appendix

Sartorius shares – an attractive investment

2 1 3

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Sartorius Stedim Biotech S.A. Stock market listed in France

55

The ownership relates to outstanding shares and thus excludes treasury shares. Information on shareholdings and shares in free float pursuant to the disclosure requirements of Sections 33 et seq. of the German Securities Trading Act (WpHG) and the shareholders’ own disclosures. The legal disclosure requirements refer only to voting shares and not to non-voting preference shares.1

100%~74%

Other Sartorius subsidiaries

Lab Products & Services divisionBioprocess Solutions division

Sartorius Group operational setup

Sartorius AG (~68.4m shares)Stock market listed in Germany1

Ordinary shares (~34.2m shares)

~55% Administered by executor~38% Bio-Rad Laboratories

~7% Free float

91.2m shares~74% Sartorius AG~26% Free float

Sartorius Group legal setup

Preference shares (~34.2m shares)

~72% Free float~28% Bio-Rad Laboratories

Appendix

Sartorius legal & operational structure

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ISIN DE0007165631 (preference share)DE0007165607 (ordinary share)

Ticker SRT3 (preference share) | SRT (ordinary share)

Number of 68,415,862 - thereof pref. shares: 34,189,853shares (excluding ~3.3m treasury shares); ord. shares:

34,226,009 (excluding ~3.2m treasury shares)

Indices DAX 50 ESG | MDAX | TecDAX | MSCI EuropeCDAX | Prime All Share Index | Technology All Share Index | STOXX Europe 600

Market cap. €32.9bn (as of February 16, 2021)

Appendix

Share price performance

0%

100%

200%

300%

400%

500%

600%

700%

800%

900%

Jan-

16

Mar

-16

May

-16

Jul-1

6

Sep-

16

Nov

-16

Jan-

17

Mar

-17

May

-17

Jul-1

7

Sep-

17

Nov

-17

Jan-

18

Mar

-18

May

-18

Jul-1

8

Sep-

18

Nov

-18

Jan-

19

Mar

-19

May

-19

Jul-1

9

Sep-

19

Nov

-19

Jan-

20

Mar

-20

May

-20

Jul-2

0

Sep-

20

Nov

-20

Jan-

21

Sartorius (prefs.)

Sartorius (ord.)

Sartorius Stedim Biotech

DAX

MDAX

MSCI Europe

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Fluid management

PurificationFiltration

Fermentation

A sampling of the Bioprocess Solutions’ product portfolio

Appendix

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Pipettes

BioanalyticsLab balances | Lab water systems

Lab filtration | Microb. analysis

A sampling of the Lab Products and Services’ product portfolio

Appendix

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Rainer Lehmann, CFO

Joined Sartorius in 2005Member of the Board since 2017

Finance, Information Technology, Business Processes

Joachim Kreuzburg, CEO

Joined Sartorius in 1999Member of the Board since 2003

Group Strategy, Corporate Research, Human Resources, Legal & Compliance, Communications

René Fáber

Joined Sartorius in 2002Member of the Board since 2019

Bioprocess Solutions Division

Gerry Mackay

Joined Sartorius in 2015Member of the Board since 2019

Lab Products & Services Division

Appendix

Executive Board of Sartorius AG

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Petra Kirchhoff

Head of Corporate Communications & IR

Phone: +49.551.308.1686E-mail: [email protected]

Sartorius Corporate Administration GmbHOtto-Brenner-Straße 2037079 Göttingen, Germany

March 26, 2021 Annual Shareholders' Meeting | Göttingen

April 21, 2021 Publication First-Quarter Results 2021 | Göttingen

Ben Orzelek

Head of Investor Relations

Phone: +49.551.308.1668E-mail: [email protected]

Appendix

Financial calendar and contacts

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Visit our IR website or click here.