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Bradley A Levitt, DPM April 21, 2017 To Achieve Limb Salvage The Wounds Must Heal

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Page 1: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

Bradley A Levitt, DPM

April 21, 2017

To Achieve Limb Salvage

The Wounds Must Heal

Page 2: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Disclosures

None

Page 3: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Limb Salvage Statistics Amputation (per 1000 patients with

Diabetes)

• Toes 1.8

• Foot 0.5

• Below Knee 0.9

• Above Knee 0.4

Centers for Disease Control and Prevention. 2007 National Diabetes Fact

Sheet. Atlanta, GA: U.S. Department of Health and Human Services, Centers

for Disease Control and Prevention, 2008.

Page 4: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Limb Salvage

• Size

– Length, Width, depth

• Location

– Forefoot, midfoot, hindfoot

– Joint

– Bone Prominence

• Appearance

– Wound bed

– Surrounding tissue

– Exudate

– Smell

Page 5: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Wound Healing

Page 6: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Factors

• Adequate Pedal Circulation

• Infection Control

• Biomechanics

• Host Factors

Page 7: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Circulation

Tissue Perfusion

Please Do this!!!!!!!!!!!!!!

Page 8: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Angiogram

• Procedure Selection

• Dominant Flow

Page 9: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Angiosomes

Taylor GI, Pan WR. Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr Surg

1998;102(3):599–616.

Page 10: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Fluorescent Intraoperative Tissue Angiography

• Arterial Perfusion

• Venous Outflow

Page 11: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Fluorescent Intraoperative Tissue Angiography

Page 12: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Infection Control

• Abscess Drainage

• Tissues Debridement

– Digit amputations

– Ray resections

– Joint resections

Page 13: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Infection Control

• Intravenous Antibiotics

• Antibiotic Vehicles – Polymethylmethacrylate (PMMA)

– Collagen – Gentamicin Sponge

– Lactic Acid Polymers

Page 14: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Biomechanics

• Weight Distribution

– Bone Architecture

– Tendon Balancing

Page 15: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Page 16: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Host Factors

• Medical comorbidities

• Social Conditions

Page 17: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Limb Salvage

Page 18: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Reconstructive Ladder

Page 19: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Primary closure

Page 20: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Amputations

• Preservation of Foot Architecture

– Foot length

– Plantar Grade

Page 21: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Reconstruction

Page 22: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Negative Pressure Wound Therapy

• Soft tissue management

• 75-125mmhg

Page 23: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Vac w/ fluids Solution Class Solution

Biguanides Polyhexanide 0.1% (Prontosan)

Polyhexanide 0.2 or 0.4%

Isotonic Solutions Normal Saline

Lactated Ringer's

Hypochlorite Based Solutions Sodium Hypochiorite 0.125%

Microcyn

Silver Nitrate Silver Nitrate 0.5%

Others benzalkornium chloride

octenide dihidrochloride

malfenide acetate

-Kim PJ, The impact of negative-pressure wound therapy with instillation compared with standard negative-

pressure wound therapy: a retrospective, historical, cohort, controlled study. Plast Reconstr Surg. 2014

Mar;133(3):709-16. doi: 10.1097/01.prs.0000438060.46290.7a.

-Paola DL, Diabetic foot wounds: the value of negative pressure wound therapy with instillation. Int Wound J. 2013

Dec;10 Suppl 1:25-31. doi: 10.1111/iwj.12174.

Page 24: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Reconstruction

Page 25: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Tissue Equivalents

ACell® UBM Hydated/lyophilized Wound Dressing • Affinity™ • AlloPatch HD™ • AlloSkin™ • AlloSkin™ RT • Allowrap™ • Amnioband®/Guardian • AMNIOEXCEL® • Amniofix® • Aongen™ Collagen Matrix • Architect® ECM, PX, FX • ArthroFlex™ (FlexGraft) • Atlas Wound Matrix • Avagen Wound Dressing • AxoGuard® Nerve Protector (AxoGen) • BioDDryFlex® • BioDfence/BioDfactor • CellerateRX®(CRXa™) • Clarix® • Clarix® Flo • CollaCare® • CollaCare® Dental • Collagen Wound Dressing (Oasis Research) • CollaGUARD® • CollaMend™ • CollaWound™ • Collexa® • Collieva® • Conexa™ • Coreleader Colla-Pad • CorMatrix® • Cymetra® • Dermadapt™ Wound Dressing • Dermapure™ • DermaSpan™ • Dermavest™ • DressSkin • Durepair Regeneration Matrix® • Endoform Dermal Template™ • ENDURAgen™ • Excellagen • ExpressGraft™ • E-Z Derm™ • FlexiGraft® • FortaDerm™/PuraPly™ • GammaGraft • GraftJacket® Xpress, injectable • GUARDIAN • Hyalomatrix® • Hyalomatrix® PA • hMatrix® • Integra™ Flowable Wound Matrix • Integra™ Bilayer Wound Matrix • MariGen/Kerecis™ Omega3™ • MatriDerm® • MatriStem® Burn Matrix • MatriStem® Micromatrix Protocol Bioengineered Skin and Soft Tissue Substitutes Last Review Date: 11/16 Page 6 of 16 • MatriStem® Wound Matrix • Matrix HD™ • Mediskin® • MemoDerm™ • NeoForm™ • Neox® Flo • Neox® Cord • Neox® Wound Allograft • NuCel • NuShield™ • Oasis® Burn Matrix • Oasis® Wound Matrix • Oasis® Ultra • Pelvicol®/PelviSoft® • Permacol™ • Plurivest™ • PriMatrix™ • Primatrix™ Dermal Repair Scaffold • Puros® Dermis • RegenePro™ • Repliform® • Repriza™ • Revitalon™ • StrataGraft® • Strattice™ (xenograft) • Suprathel® • SurgiMend® • Talymed® • TenoGlide™ • TenSIX™ Acellular Dermal Matrix • TissueMend • TheraForm™ Standard/Sheet • TheraSkin® • Unite® Biomatrix • Veritas® Collagen Matrix • XCM Biologic® Tissue

Matrix • XenMatrix™ AB

Page 26: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Tissue Equivalents

Diabetic Ulcers Apligraf®

Dermagraft®

Integra® Dermal Regeneration Template

Amniotic Membrane Graft

Venous Ulcers Apligraf®

Oasis™ Wound Matrix

Page 27: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Soft tissue Reconstruction

Page 28: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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STSG

• 0.008-0.030 in

Page 29: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Split Thickness Skin Grafts

Page 30: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Soft tissue Reconstruction

Page 31: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Local Random Flaps

• Rotational

Page 32: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Local Random Flap V to Y

Page 33: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Local Random Flaps

Rotational Flap

Page 34: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Page 35: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Local Muscle Flaps

• Type 1: One vascular pedicle

• Type 2: Dominant pedicle(s), minor pedicles

• Type 3: Two dominant pedicles

• Type IV: Segmental vascular pedicle

• Type V: One dominant pedicle and secondary segmental.

Page 36: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Abductor Hallucis

• Coverage

– Medial Ankle

– Calcaneus

– Hindfoot

– Plantar heel

– Medial Midfoot

Page 37: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Abductor Digiti Minimi

• Coverage

– Lateral ankle

– Calcaneus

– Lateral Midfoot

– Plantar Lateral heel

Page 38: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Flexor Digitorum Brevis

• Coverage

– Heel Pad

Page 39: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Pedicle Flaps MPA

• Pedicle Length

• Up to 3 cm

• Coverage

• Medial hindfoot

• Heel

• Ankle

Page 40: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Reverse Sural

• Pedicle – Perforating Peroneal

• 5-13cm above Lateral Malleolus

• Coverage

– Achilles

– Heel pad

Page 41: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Free Tissue Transfer

Call Plastics!!!!!

Page 43: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Last Resort

Page 44: To Achieve Limb Salvage The Wounds Must Healconceptsinvasculartherapies.com/pdf/2017/Friday... · Angiosomes of the leg: anatomic study and clinical implica- tions. Plast Reconstr

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Thank You