to introduce myself - universiteit...

MERIT Metabolic Reprogramming by Induction of

Transcription 1. Annual meeting

Madrid, 22.11. – 23.11.2011

MERIT - 1. Annual Meeting, Sylvia Walter

To introduce myself ¡  Sylvia Walter

¡  Biologist

¡  Last position: postdoc at the IMAU, Utrecht

¡  Global atmospheric H2 budget by using isotopologues

¡  Current position: Project manager of two ITN projects

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To introduce myself Project Management

¡  Communication channel for beneficiaries, EC and public

¡  Responsible for everything except science ¡  Giving information ¡  Writing reports ¡  Support coordinating

meetings and courses ¡  Design and update

website ¡  Financial management

… this means:

¡  Management is team work!

¡  Your input is welcome and needed, but also requested!

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WELCOME ¡  General overview

Marie Curie ITN projects

¡  General overview MERIT

¡  History

¡  Contractual details

¡  Structure

¡  Financial aspects

¡  Training

¡  Practical issues

¡  Career development plan

¡  Reporting

¡  Participant Portal

¡  Website

¡  Mid term meeting

¡  Last but not least

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Marie Curie ITN projects ¡  Organized within the 7th Framework Program (FP 7)

¡  FP 7: two main strategic objectives

¡  To strengthen the scientific and technological base of European Industry

¡  To encourage its international competitiveness, while promoting research that supports EU policies

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Marie Curie ITN projects ¡  Different programs within FP 7

¡  People

¡  Marie Curie Actions

¡  Life-long training

¡  Industry-Academia

¡  Initial Training Networks ¡  International dimensions

¡  Mobility & Excellence

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• Various grants • 4 Bill. €

• Individual persons

• Career development

• 4.8 Bill. €

• Research teams

• Fundamental research •  7.5 Bill €

• Consortia • All subjects • 32 Bill. €

Cooperation Ideas

Capacities People


MARIE CURIE ITN projects Main objectives are

¡  Attract, train, retain researchers in Europe

¡  Promote mobility across borders, sectors and disciplines

¡  Improving the career perspectives

¡  Offering structured training in well defined areas (scientific and/or technological)

¡  Providing complementary skills training for matching both public and private sectors needs

¡  Exposing researchers to the “real world” of enterprises

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Marie Curie ITN projects ¡  more general information

¡  www.ec.europa/research/fp7

¡  www.cordis.europa/fp7

¡  http://cordis.europa.eu/fp7/mariecurieactions/itn_en.html

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MERIT overview: history

¡  MEtabolic Reprogramming by Induction of Transcription

¡  7 beneficiaries from 6 countries (NL, DE, AT, SP, PT, BE) and 1 associated partner (Nunhems, NL)

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August 2009 (call: FP7-people-2010-ITN)

2008

April 2010

November 2010

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December 2009 MERIT - 1. Annual Meeting, Sylvia Walter


January 2011

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December 2014



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MERIT overview: contractual details

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between partners between partners and EU

Leg

ally

eng

ag

ing

Treaty of the EU Rules for Participation Grant Agreement

Consortium Agreement

Guidelines (e.g. financial, IPR, reporting)



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Grant Agreement consist of

¡  Core Grant Agreement

¡  Annexes ¡  Annex I Description of work ¡  Annex II General conditions ¡  Annex III Specific provisions ¡  Annex IV Form A accession beneficiary ¡  Annex V Form B accession new beneficiary ¡  Annex VI Form C Financial statement ¡  Annex VII Form D / E Terms of reference ¡  certificates



Annex I

¡  Description of what promised to EC

¡  Joint research program, recruitment planning, training, milestones, deliverables

¡  Unique for each project

¡  All reports assessed with respect to Annex I

Core Grand Agreement

¡  List of beneficiaries

¡  Duration

¡  Reporting periods

¡  Financial contribution of EC

¡  Special clauses

¡  Communication addresses

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Annex III

¡  Specific provisions, specific for ITN´s

¡  Consists of ¡  Definitions ¡  Part A: implementation of the

project ¡  Performance obligations,

Selection of researchers, Beneficiary´s relationship with the researcher, Confidentiality, publicity

¡  Part B: financial provisions ¡  Eligible costs

¡  Part C: Intellectual property rights ¡  Access rights

Annex II

¡  General conditions and common to all Marie Curie Actions

¡  Consist of ¡  Definitions ¡  Part A: Implementation of the

project ¡  Tasks and responsibilities,

Reporting, Subcontracting, suspension

¡  Part B: Financial provisions ¡  Eligible costs, Audits, financial

penalties ¡  Part C: Intellectual property rights

¡  Foreground, Access rights ¡  Final provisions


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Coordinator (II.2)

¡  Communication intermediary consortium - EC

¡  Administration and distribution of financial contribution of the EC

¡  Monitor compliance of GA

¡  Communicate / submit reports

Beneficiary (II.3 and III.2.2)

¡  Carry out work as identified in Annex I

¡  Provide infrastructure and reasonable assistance to the researcher

¡  Inform EC via Coordinator

¡  Deliver financial statement

¡  Make reports

¡  Record and update contact details of researchers for at least 3 years after end of the project

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MERIT overview: structure

¡  MEtabolic Reprogramming by Induction of Transcription

¡  7 beneficiaries from 6 countries (NL, DE, AT, SP, PT, BE) and 1 associated partner (Nunhems, NL)

¡  Project summarized in 6 work packages (WP)

¡  4 scientific WP´s

¡  1 training WP

¡  1 management WP

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MERIT overview: structure

¡  Main training objective

¡  Educate the future top-performers of the European biotech sector

¡  Main scientific objective

¡  Investigate the signal transduction pathway regulating the Low Energy Syndrome (LES) in plants

¡  Evaluate plant stress responses and assess the industrial potential

¡  9 milestones, resulting in 25 deliverables

¡  5 meetings

¡  9 courses

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MERIT overview: financial aspects

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Final Payment Total Funding -/- payments thus far

Interim Payment

25 %

Prefinancing

60 %

Guarantee fund

5 %

Duration of project

100 %

Reports



Category A B C D E G H Total

Beneficiary

Living + mobility allowance

Travel allowance

Career exploratory allowance

par>cipa>on expenses of eligible researchers

research / training / transfer of knowledge programe expenses

Management ac>vi>es

contribu>on to overheads 2881853

408 personmonths

UU 431382 8000 6000 57600 115200 196828 61818 876828

Actual indirect costs

UWUERZ 132032 3000 2000 21600 432000 0 20183 220598


UNIVIE 426241 8000 6000 57600 115200 2500 61305 676846

Special transi;onal flat rate

UPM 135636 3000 2000 21600 43200 0 20543 225979


UTU 264064 6000 4000 43200 86400 2500 40366 446530


FCG-‐IGC 122420 3000 2000 21600 43200 0 19222 211442


BBS 133500 3000 2000 21600 43200 0 20330 223630 Simplified method

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¡  Category A: Living and mobility allowance

¡  Living allowance

¡  Salary (before any deductions)

¡  Depends on level of experience

¡  36700 € ESR / 56400 € ER

¡  Corrected by the country coefficient

¡  Mobility allowance

¡  Depends on family status (married, children)

¡  800 € per month / 500 € per month

¡  Corrected by the country coefficient



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¡  Category B: Travel allowance ¡  Fixed amount between 250 € and 2500 € / year ¡  Depends on distance between place of origin and host

institution

¡  Category C: Career exploratory allowance ¡  Fixed amount of 2000 € / project ¡  For the fellows to use on their own discretion

¡  Category D: participation expenses of fellows ¡  Fixed amount of 300 € or 600 € / fellow month ¡  Used for research and training activities ¡  Managed by the host institution



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¡  Category E: research / training / transfer of knowledge program expenses ¡  Fixed amount 1200 € / fellow month ¡  Used for performance of the project

¡  Publications, secondment, training actions, teaching material, network meetings, organization, …

¡  Managed by the host institution

¡  Category G: management activities ¡  Specified during negotiation (max. 7 %) ¡  Salary of manager, costs for audits or certificates of financial

statements, reports, …

¡  Category H: overheads ¡  Max. 10 % of the total direct costs / period



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¡  Category A – B – C ¡  Paid directly to the fellow

¡  Category D ¡  Used for the fellow

¡  Category E – G - H

¡  Used for the performance of the project



Costs must be:

¡  Actual

¡  Incurred by the participant

¡  Incurred during the project

¡  Determined in accordance with the usual accounting and management principles and practices of the participants institution

¡  EC reimbursement shall not give rise to a profit

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Eligible costs

¡  Direct costs ¡  Salary ¡  Travel ¡  Consumables ¡  Equipment ¡  Subcontracting

¡  Indirect costs ¡  Secretariat, administration ¡  Housing, office supplies, lab ¡  …

Non-eligible costs

¡  Identifiable indirect taxes, incl. VAT

¡  Duties

¡  Interest owed

¡  Provisions for future losses or charges

¡  Exchange losses, cost related to return on capital

¡  Costs declared/incurred/reimbursed in another EC project

¡  Debt and debt service charges

¡  excessive or reckless expenditure

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Documents requested in case of audits

¡  Proof of salary payments and deductions for social security

¡  Fellow contract

¡  Declaration on conformity

¡  Evidence that fellow worked on the project

¡  Evidence of the eligibility of the fellow

¡  Records to comply with the accounting rules of your institution

¡  Receipts of expenditure (Cat. G)

¡  Timesheets for personnel costs (Cat. G)

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Year 1 Year 2 Year 3 Year 4

MERIT overview: reporting



1. Progress report

¡  Within 30 days after month 12

¡  No financial report required

¡  Contract deliverable update

¡  Template provided by management

¡  Submitted via project management

Mid term report

¡  30 days before Mid term meeting

¡  No financial report required

¡  Updated 1. progress report



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1. Periodic report

¡  Within 60 days after month 24

¡  Base for interim payment!

¡  financial report required



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¡  Includes

¡  Declaration by coordinator

¡  Publishable summary

¡  Overview of work progress and objectives

¡  Project management report

¡  List of submitted certificates


MERIT overview: training

¡  Highly interdisciplinary

¡  using methods from molecular biology, genetics, biochemistry, bioinformatics, evolutionary biology, cell biology

¡  Knowledge transfer via

¡  Close supervision by one supervisor and one co-supervisor

¡  Personal communication

¡  Conferences, meetings

¡  Technology centers

¡  Local training

¡  Network training

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¡  ESR 1: Monika Tomar (SV: Johannes Hanson, cSV: Ulrike Zentgraf)

¡  ESR 2: Alessia Peviani (SV: Berend Snel, cSV: Wolfram Weckwerth)

¡  ESR 3: Lorenzo Pedrotti (SV: Wolfgang Dröge-Laser, cSV: Christina Chaban)

¡  ESR 4: Andrea Simeunovic (SV: Markus Teige, cSV: Elena Baena-González)

¡  ESR 5: Ella Nukarinen (SV: Wolfram Weckwerth, cSV: Johannes Hanson)

¡  ESR 6: not decided yet (SV: Jesus Vicente-Carbajosa, cSV: Woflgang Dröge-Laser)

¡  ESR 7: Abhroop Garg (SV: Christina Chaban, cSV: Jesus Vicente-Carbajosa)

¡  ESR 8: Carles Llorca (SV: Ulrike Zentgraf, cSV: Matthew Hannah )

¡  ESR 9: Mattia Adamo (SV: Elena Baena-González, cSV: Markus Teige)

¡  ESR 10: Filipa Tomé (SV: Matthew Hannah, cSV: Johannes Hanson)

¡  ER 1: Magdalena Gamm (SV: Johannes Hanson, cSV: Wolfram Weckwerth)

¡  ER 2: Thomas Nägele (SV: Wolfram Weckwerth, cSV: Berend Snel)

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¡  6 Technology Center (TC) to maximize knowledge transfer

¡  Working visits of approximately 4 weeks to the TC to learn essential techniques

¡  At least 2 planned for each fellow

¡  TC 1: Analysis of mRNA abundance data and bioinformatics analysis(Johannes Hanson, Berend Snel)

¡  TC 2: Metabolomic analysis using GC-MS (Wolfram Weckwerth) ¡  TC 3: Protein interactions – MS analysis of proteins, yeast (Markus Teige) ¡  TC 4: Microscope analysis of cells and tissues (Christina Chaban) ¡  TC 5: High-throughput protoplast technology (Wolfgang Dröge-Laser)

¡  TC 6: Phenotypical growth analysis (Matthew Hannah)

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Local training

¡  Close scientific supervision by daily supervisor and co-supervisor

¡  Enrolment in local training ¡  Experimental skills ¡  Analysis skills ¡  Language courses ¡  Complementary skills

training ¡  Teaching / supervision

assistants

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Network training

¡  Exchange between partner laboratories (visit TC´s)

¡  External collaborations

¡  following network events and courses

¡  5 research skill training workshops

¡  4 complementary skill training workshops


MERIT practical issues: career development plans

¡  Absolutely required (deliverable 7, month 12)

¡  Individually for each ESR

¡  formulated at the beginning of project (supervisor in cooperation with the ESR)

¡  Includes main goals on research and complementary skills (e.g. scientific results, language courses, meetings, paper)

¡  short and long term perspective

¡  Update during annual meeting

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Year 1 Year 2 Year 3 Year 4

MERIT practical issues: reporting


MERIT practical issues: reporting

¡  Template for reports

¡  Fill in as requested

¡  Contact me if there are questions

¡  Keep the deadlines!

¡  Your first deadline:

31.12.2011

1. Progress report

To be send to me!

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MERIT practical issues: Participant Portal

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¡  http://ec.europa.eu/research/participants/portal/appmanager/participants/portal

¡  To be submitted by the coordinator ¡  All reports except for financial reports ¡  Amendments

¡  To be submitted by the beneficiaries

¡  Financial statement – Form C ¡  Certificate of financial statement (if applicable) ¡  Declarations on the conformity ¡  Notifications ¡  Vacancies within the project

¡  To be submitted by the ESR´s / ER´s ¡  Questionnaires



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¡  Login

¡  If you are using the PP for the first time, you have to register



¡  Go to “my projects”

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MERIT practical issues: website

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MERIT practical issues: website

¡  http://theory.bio.uu.nl/MERIT/html/index.html

¡  Contains information about

¡  Participants and projects

¡  Meetings, courses, conferences

¡  Technology centers

¡  EU documents

¡  Publications

¡  Interesting links to share

¡  More suggestions ???

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Input from you!


MERIT practical issues: Mid term meeting

¡  2. annual meeting

¡  Lisboan (hosted by Elena)

¡  Between project month 20 – 22

¡  Project officer will choose date

¡  Mandatory!

¡  Mid term report 4 weeks BEFORE the meeting to be submitted

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MERIT practical issues: last but not least

¡  Thanks for your attention! ¡  Election of a student representative

¡  Evaluation of the course

¡  Evaluation of the presentations today

¡  Group photo during lunch

¡  WP discussions during lunch if neccessary

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