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Trends in Cancer Incidence: Highlights Michael Rosskamp Frédéric Calay

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Page 1: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

Trends in Cancer Incidence: Highlights

Michael Rosskamp

Frédéric Calay

Page 2: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

Breast34%

Colorectal12%

Lung9%

Other46%

Other47%

Colorectal13%

Lung15%

Prostate 25%

(excl. non-melanoma skin cancers)

36,243 cases 53%

68,216 new cancer diagnoses in 2016

Page 3: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

Breast34%

Colorectal12%

Lung9%

Other46%

Other47%

Colorectal13%

Lung15%

Prostate 25%

(excl. non-melanoma skin cancers)

36,243 cases 53%

31,973 cases47%

68,216 new cancer diagnoses in 2016

Page 4: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

Global trends in cancer incidence rate, Belgium 2004-2016

≈?

Liver

Melanoma

TestisThyroid

Colorectal

Lung (F)

Head & neck (F)Kidney (M)

Sarcoma

Breast

Head & neck (M)

Oesophagus (F)

Ovary

Corpus uteri

Stomach (M)

Lung (M)

Bladder (M)

Prostate

Pancreas

Cervix uteri

Brain

Renal pelvis

Myeloid malignancies

Page 5: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

Breast34%

Colo-rectal12%

Lung9%

Other46%

Other47%

Colorectal13%

Lung15%

Prostate 25%

Prostate cancer: 9,050 cases

Breast cancer: 10,735 cases

Before 75 years: Before 75 years:

68,216 new cancer diagnoses in 2016

(excl. non-melanoma skin cancers)

Page 6: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin
Page 7: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin
Page 8: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin
Page 9: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin
Page 10: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin
Page 11: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

Breast cancer: incidence rate 2004-2016

0

20

40

60

80

100

120

140

'99 '00 '01 '02 '03 '04 '05 '06 '07 '08 '09 '10 '11 '12 '13 '14 '15 '16

WSR

N/1

00

,00

0

Incidence year

Belgium Flemish Region Walloon Region Brussels Capital Region

Page 12: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

Breast cancer in Europa (Estimated WSR 2018)

Source: ECIS - European Cancer Information SystemFrom https://ecis.jrc.ec.europa.eu, accessed on 19/11/2018© European Union, 2018

Page 13: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

Breast34%

Colorectal12%

Lung9%

Other46%

Other47%

Colorectal13%

Lung15%

Prostate 25%

Lung cancer: 5,439 cases

Lung cancer: 2,735 cases

(excl. non-melanoma skin cancers)

68,216 new cancer diagnoses in 2016

Page 14: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

0

10

20

30

40

50

60

70

'04 '05 '06 '07 '08 '09 '10 '11 '12 '13 '14 '15 '16

WSR

N/1

00

,00

0

Incidence year

Incidence - Males Incidence - Females Mortality - Males Mortality - Females

AAPC incidence: 3.5% [3.0; 4.0]

AAPC incidence: -1.7% [-1.9; -1.4]

Lung cancer: incidence rate 2004-2016 and mortality rate 2004-2015

Page 15: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

Invasive tumours: Incidence trends projected to 2025

(excl. non-melanoma skin cancers)

Page 16: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

Breast34%

Colorectal12%

Lung9%

Other46%

Other47%

Colorectal13%

Lung15%

Prostate 25%

Colorectal cancer: 4,714 cases

Colorectal cancer: 3,754 cases

(excl. non-melanoma skin cancers)

68,216 new cancer diagnoses in 2016

Page 17: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

0

10

20

30

40

50

'99 '00 '01 '02 '03 '04 '05 '06 '07 '08 '09 '10 '11 '12 '13 '14 '15 '16

WSR

N/1

00

,00

0

Incidence year

Belgium Flemish Region Walloon Region Brussels Capital Region

Colorectal cancer: incidence rate 2004-2016

2013 Start Screening Flemish Region

Page 18: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

Melanoma6%

Other96%

Melanoma4%

Other 96%

Melanoma

Age-specific incidence rates, 2012-2016

0

10

20

30

40

50

60

70

80

0- 5- 10- 15- 20- 25- 30- 35- 40- 45- 50- 55- 60- 65- 70- 75- 80- 85+

N/1

00

,00

0

Age group

Males Females

N(2016)=1,786

N(2016)=1,283

Page 19: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

0

5

10

15

20

25

'04 '05 '06 '07 '08 '09 '10 '11 '12 '13 '14 '15 '16

WSR

N/1

00

,00

0

Incidence year

Incidence - Males Incidence - Females Mortality - Males Mortality - Females

Incidence rate 2004-2016, mortality rate 2004-2015

AAPC incidence: 5.1% [4.0; 6.1]

AAPC incidence: 4.9% [4.1; 5.7]

Melanoma

Page 20: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

0

5

10

15

20

25

'04 '05 '06 '07 '08 '09 '10 '11 '12 '13 '14 '15 '16

WSR

N/1

00

,00

0

Incidence year

Lymphoid malignancies Myeloid malignancies Histiocytic and dendritic cell neoplasms

Incidence rate 2004-2016

Haematological malignancies(11% of all cancers, 4th cause of death from cancer)

N(2016)=7,199

AAPC 3.6% [2.7; 4.4]AAPC 3.4% [2.6; 4.2]

Page 21: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

0

2

4

6

8

10

'04 '05 '06 '07 '08 '09 '10 '11 '12 '13 '14 '15 '16

WSR

N/1

00

,00

0

Incidence year

Incidence Mortality

Ovarian cancer

AAPC incidence: -2.9% [-3.5; -2.2]N(2016)=752

Incidence rate 2004-2016, mortality rate 2004-2015

Relative survival 2012-2016

0%

20%

40%

60%

80%

100%

0 1 2 3 4 5

Rel

ativ

e su

rviv

al

Survival time (years)2004-2007 2008-2011 2012-2016

Page 22: Trends in Cancer Incidence: Highlights - kankerregister.org · Breast 34% Colorectal 12% Lung 9% Other 46% Other 47% Colorectal 13% Lung 15% Prostate 25% (excl. non-melanoma skin

Take-home messages

• Overall risk to develop cancer:

• Risk for smoking-related cancers in women and melanoma increasing:

primary prevention measures!

2013 2018