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Page 1: Trusted evidence. Informed decisions. Better health. · Such pairwise meta-analyses can only compare two agents that have been compared directly in head-to-head trials (direct evidence)

Trusted evidence.Informed decisions.Better health.

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Page 6: Trusted evidence. Informed decisions. Better health. · Such pairwise meta-analyses can only compare two agents that have been compared directly in head-to-head trials (direct evidence)

Review Section Guiding Question

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• Specific statistical model to fit NMA: Bayesian vs. frequentist setting;

• Fixed or random effects; • Multivariate meta-analysis vs. hierarchical

model.

• Account for correlated nature of multi arm studies?

• Assumptions about the heterogeneity variance and the method for estimating it should be reported

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https://training.cochrane.org/handbook/current/chapter-10#section-10-10-2
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https://datadryad.org/stash
https://figshare.com/
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‘rank’ if applicable)

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https://training.cochrane.org/handbook/current/chapter-11
https://methods.cochrane.org/cmi/welcome
https://training.cochrane.org/online-learning/cochrane-methodology/network-meta-analysis-nma
https://training.cochrane.org/network-meta-analysis-learning-live-webinar-series
https://methods.cochrane.org/about-us/cochrane-central-executive-methods-team/methods-support-unit
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https://cinema.ispm.unibe.ch/
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