ucsf informatics day 2014 - priyanka agarwal, "center for digital health innovation"

Center for Digital Health Innovation at UCSF

San Francisco, June 10, 2014

Priyanka Agarwal

Rhona Snyman

UCSF’s Center for Digital Health Innovation


About us

2


Road Map

3

• Overview of CDHI

• UCSF/Samsung Innovation Lab

• Internal Innovation

• External Partnerships

• CDHI & the ITA


CDHI Overview


The Vision

5

To improve health worldwide, we

envision and realize new technologies,

developed at UCSF and beyond, and

evaluate them in clinical settings.

Guided by science, we catalyze the

new era of precision medicine.

Center for Digital Health Innovation at UCSF 6

The context: Interest in digital health is growing

186 companies funded >2M in 2013


…And little involvement from medicine

186 companies funded >2M in 2013


Enter CDHI


Focus


Unique Value Proposition

10

• Unified team of MDs, IT engineers, EHR experts, clinical

trial specialists, and security specialists

• Access to UCSF’s clinical trial and research infrastructure

• Deep knowledge around EHR integration and development


Team

11

CMIOs Engineers ResearchersSecurity experts

Medical Educators

Licensing Officers

Project managers


Team

12


Key UCSF Partners for Success

CDHI

ITACHR

ITS

PLR

CHCV

CTSIQB3

MedCtrIT

SOM

ISU

COI


Endpoints for success

14

• In collaboration with faculty, staff, start-ups, and industry partners new digital

health concepts and technologies are reaching the market

• CDHI trials of new digital health technologies are published in scientific

journals, with UCSF seen as a leader for the validation of new technologies

• New partnerships with industry and venture capital leaders are in place to

accelerate dHealth innovation and public benefit


UCSF/Samsung Digital Health Innovation Lab


Mission

16

To accelerate validation and commercialization of

promising new sensors, algorithms, and digital health

technologies for preventive health solutions


First collaboration: Simband & the Sami Platform

17


Sami Platform

18


Samsung Innovation Lab


Working Across Spheres

20

CONSUMERS

• engagement

• motivation

• education

• Communication

CLINICIANS

• Beside tools

• diagnostic &

decision support

• process efficiency

RESEARCHERS

• data collection

• behavior change

• real-time feedback

• collaboration


CDHI & Internal Innovation


Internal Innovation Goals

22

• Incubate best of internally developed technologies

• Support promising technologies via Catalyst award

• Promote commercialization via external partnerships (Samsung center, other startup/later-stage partnerships)


Innovation: Inaugural Portfolio


Case Study: Health eHeart


Case Study: eReferrals & AristaMD

25

• UCSF PIs developed successful technology at UCSF

• Interest in commercializing technology with AristaMD

• Need to balance PI interests with those of UCSF

• Need to convey process for external partnership to PIs

• Conflict of interest

• Income distribution


CDHI & External Activities


External Innovation Goals

27

• Co-development deals with UCSF supporting technical & workflow development

• Clinical Trial development & support

• Goal for partnership rather than fee-for-service arrangement


Opportunities for external partners at CDHI

28

Clinical expertise

Patient expertise

Data

Workflow integration

Technical (EHR) Integration

Clinical trial design and implementation

FDA guidance

Privacy, risk guidance

Access to network of hospitals, clinics, care networks


Framework for External Partnerships

2929

Initial MeetingITA

involvement

Technical co-development

plan

Trial co-development

planImplementation

Implementation

Scientist

PIRA

Ongoing

involvement

EHR

Integration

Trial design,

clinical workflows

Industry Partnerships

BAA, privacy, riskEPIC interfaces

team

PI recruitment,

pharmacy, RN

Decision

to engage

Demo Day

Industry Partnership

Advisory Board


Experience to date

30

• ~60 early-stage companies

have reached out to CDHI

since August 2013

• Each company asked to fill

out intake survey

• Demo Days held every 4-6

weeks for CDHI team to

meet with multiple

companies


Case Study: Smartdose

31


Smartdose: Considerations raised

32

• Storage of data: Cloud-based or on premise?

• Outline of financials for collaborative agreement: Upfront or

upon completion of work?

• Language around IP development: UCSF with first right of

refusal?


Thank You


Integration: EMERGE

34

M institutions + N Apps


Distinct from our Competitors


Demo Day

36

• Monthly opportunity for multi-disciplinary CDHI team to

hear from multiple companies in a brief period

• Initial session held on 3/11/2014

• Plan to invite other domain experts, co-sponsors

• Tracking success of companies both accepted and

declined


Takeaways

37

• Heightened interest in healthcare space

• Cloud computing considerations

• Risk considerations for UCSF vs Smartdose


Life cycle of a partnership

38

Initial MeetingIP office

involvement


plan


planImplementation

Implementation

Scientist

PIRA



39


involvement


plan


planImplementation

Decision

to engage

Demo Day


Advisory Board



40


involvement


plan


planImplementation

Decision

to engageFunding Funding Funding

IT, security,

providersFaculty

member

Research

Assistant

Demo Day Industry Partnerships


Advisory Board


Status of partnership

4141


involvement


plan


planImplementation

Implementation

Scientist

PIRA

Ongoing

involvement

EHR

Integration

Trial design,

clinical workflows

Industry Partnerships

BAA, privacy, riskEPIC interfaces

team

PI recruitment,

pharmacy, RN

ucsf informatics day 2014 - priyanka agarwal, "center for digital health innovation"

Science

resourcesmost digital

digital healthdifficult

ideasdigital health

external partners

us2 center

focus center

behalf of pis external

behalf of ucsf