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واالعتمادهيئة القومية لضمان جودة التعليم ال
University: Alexandria
Faculty : Medicine
Program Specifications
(Academic year: 2015)
واالعتمادهيئة القومية لضمان جودة التعليم ال
A. Basic Information:
1. Program title: : Doctor Degree in Hematology
2. Department offering the program; Internal medicine ( Clinical Hematology Unit)
3. Program Coordinator: Prof. Dr. Nahla A. Hamed.
4. External evaluator(s): Prof Dr Sameh Shamaa
5. Type of the program: Single
6. Date of most recent program specifications approval: October 2015 B. Professional Information:
1- Program Aims: This program is designed to provide candidates with the updated knowledge and skills that allow them to:
1.1. Deal successfully with common and difficult cases with diseases of blood and bone
marrow. 1.2. Interpret hematological manifestations of medical diseases and solid tumors.
1.3. Take decisions with emergency situation in hematology. 1.4. Apply evidence based medicine from updated reference.
1.5 Perform continuous self life-long learning
2- Acdemic reference standards (ARS)& ILOs:
Academic reference standards of Doctor Degree in Hematology designed and approved by Department of Internal Medicine (Hematology Unit) Faculty of Medicine. Alexandria
University. Based on:
Generic Academic Reference Standards (ARS): Postgraduate Medical Education, Egypt (2009). Published by National Authority for Quality Assurance and Accreditation of
Education (NAQAAE) National [http://naqaae.org/main/php/book/index.php]
Adapted from;
Specialty Training Curriculum for Hematology by Joint Royal Colleges of Physicians
Training Board (www.jrcptb.org.uk)
Domain Academic Reference
Standards (ARS)
ILOs
A. Knowledge and
understanding • – Identify Recent
advances in the field of
diagnosis and management of haematological diseases
including anaemia, coagulation disturbance and haematological
malignancies.
a1 – Identify recent advances in the causes, presentation,
complications, diagnosis and management of different types of
anemia. a2 – Identify recent advances in
haematopoiesis and stem cell
research. a3 – Identify recent advances in
diagnosis and management of inherited and acquired bone
marrow failure.
واالعتمادهيئة القومية لضمان جودة التعليم ال
• –update his knowledge regarding the drugs used
in the field of haematology, as well as blood and blood products
a4 – Identify recent advances in diagnosis, classification and
management of acute and chronic leukemias in adults.
a5 – Identify recent advances in
the classification, natural history, molecular biology, and
therapeutic modalities of hematological malignancies.
a6 – Identify recent advances in
the histological classification of lymphomas approved by the
WHO. a7 – Identify recent advances in the
diagnostic methods used in the
assessment and the management congenital coagulation and
platelet disorders,
a8 – update his knowledge in the
pharmaceuticals and blood products available for the
management of excessive bleeding.
a9 – update his knowledge in the
field of blood transfusion.
a10 – update his knowledge in
classification of
myeloproliferative disorders, the required diagnostic methods and
the therapeutic options.
a11 – update his knowledge on the
impact of systemic disease on the
blood and bone marrow.
a12 – update his knowledge in haemostatic problems in
pregnancy and solid tumors
a13 – update his knowledge regarding indications and
management of bone marrow
transplantation
a14 – update his knowledge regarding chemotherapy regimens
used in the management of
hematological malignancies.
واالعتمادهيئة القومية لضمان جودة التعليم ال
B. Intellectual
skills
▪ Analyze, deduce, extrapolate & evaluate
laboratory information to establish diagnosis and appropriate treatment planning.
▪ Take decisions in various professional situations of haematological problems according to the available data
▪ Apply evidence based medicine from updated reference.
b1 Analyze laboratory testing results
for the initial management of common and unusual
hematological disorders.
b2 Take decision in the diagnosis and appropriate treatment
planning. b3 Explain planned treatment
clearly to junior staff
b4 apply multidisciplinary team
work for managing complication
b5 Apply evidence based medicine
from updated printed and electronic reference.
C. Professional
skills • –Evaluate and improve
methods and tools used in patient management.
• –Plan professional courses to improve practice and enhance performance of juniors as regards
appropriate use of antibiotic regimens for treatment and prophylaxis in
immunosuppressed patient.
Management of complications of blood transfusion
appropriately monitoring of
anticoagulation
c1 - Plan professional courses of combination chemotherapy
regimens.
c2 – Plan professional courses for appropriate use of antibiotic
regimens for treatment and
prophylaxis in the immunosuppressed patient.
c3 – Plan professional courses for complications of blood transfusion appropriately
c4 – Plan professional courses
for use and monitoring of
anticoagulation
c5 – Evaluate and improve methods and tools used in stem
cell transplantation
c6 - Evaluate and improve methods and tools used in
diagnosis & management of
hematological emergencies.
واالعتمادهيئة القومية لضمان جودة التعليم ال
D. General and
transferrable
skills
• Communicate with colleagues in other specialties effectively for proper diagnosis and treatment of the patients.
• -Direct his assistant team throughout the work
• Write and assess patient’s reports
• -Advance his knowledge and information continuously using
different printed and electronic sources.
d1- perform full explanation of the side effects of chemotherapy to
patients. d2-communicates effectively with
patients performing transplantation
and their family. d3-Communicate effectively with
colleagues in other specialties for proper management of the patients.
d4-Perform leadership
responsibilities d5- Write and appraise reports.
d6-perform continuous self lifelong learning
d7-Upgrade his scientific knowledge
utilizing all available sources.
E. Attitudes and
ethical
behavior
• Appreciate ethical,
religious and law
regulations during his
practice.
e1 Appreciates ethical communication of informed
consent.
e2 –-Evaluates the junior staff
ability to Communicate with
terminal patients and their relatives.
e3 –Demonstrates the importance of
supportive care for successive patient outcome.
e4 –Conducts and modifies multidisciplinary team working.
e5 Evaluates the ability of juniors
to conduct sympathetically bad news including terminal
progress.
Program courses ILOs Matrix
ILOs
Course title
A
1
A
2
A
3
A
4
A
5
A
6
A
7
A
8
A
9
A
1
0
A
1
1
A
1
2
A
1
3
A
1
4
Clinical and Chemical
pathology for hematology II
Hemopoiesis II x
Iron metabolism. And x x
واالعتمادهيئة القومية لضمان جودة التعليم ال
anemia,
Acute leukemias II x x
Chronic leukemias II x x
x
Stem cell disorders II x
Lymphomas II x x
Myeloma II x x
Hemostasis II x x
Blood transfusion II x x
Hematological
manifestations of medical
diseases II
x x
Immunodeficiencies
Stem cell transplantation
Integrated hematology II
ILOs
Course title
B
1
B
2
B3 B4 B5 C
1
C
2
C
3
C4 C5 C6 D
1
D2 D
3
D
4
D5 D
6
D7 E1 E
2
E
3
E4 E5
Clinical and Chemical pathology for
hematology II
Hemopoiesis II x
Iron metabolism. And anemia, II
x x x x x
Acute leukemias II
x x x x x x x X X X X
Chronic leukemias II
x x x x x
Stem cell
disorders II
x x x
Lymphomas II x x x x x X
Myeloma II x x x x x X
Hemostasis II x x x x x
Blood
transfusion II
x x
Hematological
manifestations of medical diseases II
x x x
Immunodeficiencies
Stem cell transplantation
Integrated
hematology II
واالعتمادهيئة القومية لضمان جودة التعليم ال
2- Curriculum Structure:
-Program duration: This program is fulfilled in not less than 2 years with a maximum of 5 years (4
semesters & thesis).
-Program structure: 1. Total hours: 52 Credit hours.
2. Obligatory subjects: 32 Credit Hours. 3. Thesis: 20 Credit Hours. 4. 2 Elective Subjects: 2 Credit Hours each = 4 hours.
-Program Content:
A. Obligatory Courses:
Code Course Credit hours
Contact hours Prerequisites
lectures practical other
1 050509151 Clinical and Chemical pathology for
hematology II
1 0.5 0.5
2 05151901 Haemopoiesis II 2 1 1
3 05151902 Iron Metabolism, Iron Deficiency and
Disorders of Haem Synthesis,
Megaloblastic Anaemia, Haemolytic Anaemias, Aplastic Anaemia
4 3 1
4 05151903 Acute Leukaemias II 2 1 1
5 051511904 Chronic Leukaemias II 2 1 1
6 05151905 Stem Cell Disorders II 3 2 1
7 05151906 Lymphomas II 2 1 1
8 05151907 Myeloma II 2 1 1
9 05151908 Haemostasis II 3 2 1
10 05151909 Blood Transfusion II 2 2 -
11 05151910 Haematological manifestation of
medical diseases II
2 1 1
12 05151911 Immunodeficiencies 1 0.5 0.5
13 05151912 Stem cell transplantation 2
14 05151913 Integrated hematology II 4
B. Elective Courses:
Code Subject Credit hours
05070739 Biostatistics and Computer 1
053109151 Imaging for hematology 1
05160832 Molecular Biology 1
- Others According to the Field of the Thesis 1
3- Program Admission Requirements: According to the regulations of the credit hour by laws of the Faculty of Medicine
Alexandria University (annex).
4- Regulations for Progression and Program Completion: According to the regulations of the credit hour by laws of the Faculty of Medicine
Alexandria University (annex).
واالعتمادهيئة القومية لضمان جودة التعليم ال
5- Methods of student assessment:
Methods Intended Learning outcomes to be
assessed
1. Written Exam a1-a14, b1-b2, b5,c2-c3
2. Practical Exam B3-b4, c1,c4-c6
3. Assignments d1 – d7
4.Thesis d5-d7,e1-e5
6- Methods of program evaluation:
Evaluator Tool Sample
1. Students enrolled in the program Questionnaires.
2. Alumni --------
3. Stakeholders (Employers) Focus group
4. External Evaluator (s) Prof. Sameh Shamaa
5. Others:
Program Director: Prof Dr. Yahia Ganem Program Coordinator: Prof Dr. Nahla A Hamed
واالعتمادهيئة القومية لضمان جودة التعليم ال
COURSE DESCRIPTION
1 Code Credit hours (1) Course Prerequisites
050509015 Lectures Clinical Clinical and Chemical
pathology for hematology
II
0.5 0.5
2 Code Credit hours (2) Course Prerequisites
05151901 Lectures Clinical Haemopoiesis II
1 1
Introduction. Sites of haemopoiesis. The stromal microenvironment. Stem cell trafficking.
Organization of haemopoiesis. Haemopoietic growth factors and receptors. Clinical applications of
stem cell research. Selected bibliography. Seminars: update.
3 Code Credit hours (4) Course Prerequisites
05151902 Lectures Clinical Iron Metabolism, Iron
Deficiency and Disorders
of Haem Synthesis,
Megaloblastic Anaemia, Haemolytic Anaemias,
Aplastic Anaemia
3 1
Distribution of body iron. Cellular iron homeostasis. Normal iron balance. Iron absorption. Internal
exchange. Haem synthesis. Diagnostic methods for investigating iron metabolism. Iron deficiency
anaemia. Causes of iron deficiency. Management of iron deficiency. Pathological alterations in haem synthesis. Selected bibliography.
Megaloblastic anaemia: Introduction. Underlying basic science. Clinical features. Haematological
findings. Cobalamin. Cobalamin analogues. Causes of cobalamin deficiency. Diagnosis of cobalamin deficiency. Tests for the cause of cobalamin deficiency. Folate. Causes of folate deficiency.
Diagnosis of folate deficiency. General management of megaloblastic anaemia. Prophylactic folic
acid. Megaloblastic anaemia not due to cobalamin or folate deficiency or altered metabolism. Other
nutritional anaemias. Inherited disorders of hemoglobin. Acquired haemolytic anaemias: Introduction. Immune haemolytic anaemias. Warm-type autoimmune
haemolytic anaemias. Cold-type autoimmune haemolytic anaemias. The non-immune acquired
haemolytic anaemias. Sickle cell disease. Disorders of red cell membrane. Inherited aplastic anaemia/bone marrow failure syndromes: Introduction. Fanconi anaemia.
Dyskeratosis congenital. Shwachman-Diamond syndrome. Diamond-Black fan anaemia. Congenital
and cyclical neutropenias. Thrombocytopenia with absent radii. Congenital amegakaryocytic thrombocytopenia. Conclusion. PNH.
Seminars: update.
4 Code Credit hours (2) Course Prerequisites
05151903 Lectures Clinical Acute Leukaemias II
1 1
واالعتمادهيئة القومية لضمان جودة التعليم ال
Acute myeloid leukemia. Epidemiology of disease. Pathophysiology. Disease classification.
Cytogenetics. Treatment. Future developments. Selected bibliography.
Adult acute lymphoblastic leukaemia: Introduction. Diagnosis. Clinical manifestations. Laboratory evaluation. Differential diagnosis. Initial evaluation and supportive therapy. Chemotherapy. Stem
Cell transplantation. Outcome of all subtypes and prognostic factors. Minimal residual disease-
practical application in adult ALL. Treatment with monoclonal antibodies. ABL tyrosine kinase inhibitors in Ph/BCR-ABL-positive ALL. Selected bibliography.
Seminars: update.
5 Code Credit hours (2) Course Prerequisites
05151904 Lectures Clinical Chronic Leukaemias II
1 1
Introduction. Classification. Cytokinetics. Cytogenetics. Molecular biology. Clinical features.
Haematology. Management of chronic myeloid leukaemia in chronic phase. Treatment decisions for
newly diagnosed patients in chronic phase. Management of chronic myeloid leukaemia in advanced phase. Variants of chronic myeloid leukaemia. Selected bibliography.
Chronic lymphocytic leukaemia and other B-cell disorders: Introduction. Methodology for diagnosis.
Chronic lymphocytic leukaemia. Management. Prolymphocytic leukaemia. Hairy cell leukaemia. The leukaemic phase of low-grade NHL. Selected bibliography.
Seminars: update.
6 Code Credit hours (3) Course Prerequisites
05151905 Lectures Clinical Stem cell disorders II
2 1
Myelodysplastic syndromes. Cytogenetics. Investigations. Classifcation. Pathogenesis. Prognosis.
Management.
Myeloproliferative disorders: The polycythaemia. Polycythaemia rubra vera. Essential thrombocythaemia. Idiopathic myelofibrosis.
Bone marrow transplantation.
Seminars: update.
واالعتمادهيئة القومية لضمان جودة التعليم ال
7 Code Credit hours (2) Course Prerequisites
05151906 Lectures Clinical Lymphomas
1 1
Non Hodgkin's lymphomas. Classifications. Epidemiology. Aetiology. Cytogenetics & oncogenes.
Clinical features. Investigations. Staging. Treatment. Specific types.
Hodgkin's lymphoma: Epidemiology. Classification. Pathogenesis. Presentation. Staging. Prognostic factors. Therapy.
8 Code Credit hours (2) Course Prerequisites
05151907 Lectures Clinical Myeloma
1 1
Myeloma: Definition. Pathogenesis. Clinical features. Laboratory findings. Treatment. Monoclonal
gammopathy of uncertain significance. Waldenstrom macroglobulinaemia. Plasma cell leukemia.
Non-secretory myeloma. Hairy-chain diseases. Seminars: update.
9 Code Credit hours (3) Course Prerequisites
05151908 Lectures Clinical Haemostasis II
2 1
Overview. Blood vessels. Platelets. Coagulation factors. Naturally occurring inhibitors. Fibrinolysis. Inherited bleeding disorders: Haemophilia A. Haemophilia B. Gene therapy. Von Willibrand disease.
Acquired coagulation, platelet & vascular bleeding: Disseminated intravascular coagulation.
Coagulopathy & massive blood loss. Vitamin K deficiency. Idiopathic thrombocytophric purpura. Non-thrombotic vascular purpuras. Inherited thrombophilia. Acquired venous thrombosis. TTP.
Congenital platelet disorders.
Seminars: update.
10 Code Credit hours (2) Course Prerequisites
05150909 Lectures Clinical Blood Transfusion II
2 -
Blood component transfusion indications and complications.
11 Code Credit hours (2) Course Prerequisites
05151910 Lectures Clinical Hematological
Manifestations of Medical
Diseases
1 1
Connective tissue disorders liver disease, renal disease, neurological disorders.
12 Code Credit hours (1) Course Prerequisites
05151911 Lectures Clinical Immunodeficiencies
13 Code Credit hours (2) Course Prerequisites
05151912 Lectures Clinical Stem cell transplantation
واالعتمادهيئة القومية لضمان جودة التعليم ال
14 Code Credit hours (2) Course
05151913 Lectures Clinical Integrated hematology II 05151901-12
Course Specifications
University: Alexandria
Faculty: Medicine
Department:
Course InformationCourse Code:
05151906Course Name lymphoma II
Program in which the Course is Given: doctorate program in hematology
Number of Credit Hours2 Theoretical Clinical/Practical
Course Aimsto provide candidates with the updated knowledge and skills that allow themtodiagnose and manage successfully Lymphomas
Intended Learning Outcomes (ILOs)Program ILO (refer to programmatrix)
Course ILOs
A. KnowledgeandUnderstanding
a5 – Identify recent advances inthe classification, naturalhistory, molecular biology, andtherapeutic modalities ofhematological malignancies.
a6 – Identify recent advances in thehistological classification oflymphomas approved by theWHO.
a3 –update his knowledge in WHOclassification of lymphomaa4 Identify recent advances in the drugs used
in Lymphomas according to WHOclassification
B. Intellectualskills
b1 Analyze, deduce, extrapolate &evaluate laboratory testingresults for the initialmanagement of common andunusual hematologicaldisorders.
b2 Take decision in the diagnosisand appropriate treatmentplanning.
b5 Apply evidence based medicine
b1 Analyze & evaluate available laboratoryinformation to establish treatment planof Lymphomas.
b2 Analyze & deduce laboratory tests toestablish treatment of uncommon typesof Lymphomas.
b3 Take decisions in various professionalsituations in lymphoma
b5 Refer to evidence based medicine in
11
from updated printed andelectronic reference.
managing casesb6 Refer to updated reference in dealing with
difficult cases.
C.ProfessionalandPractical Skills
C1-Plan professional courses ofcombination chemotherapyregimens
C1-Evaluate and improve methods and toolsused in management of LymphomasC2–Plan professional courses to improve
practice and enhance performance ofjuniors as regards appropriate treatmentof Lymphomas
D. General Skills d1- perform full explanation of theside effects of chemotherapy topatients.
d1-Performleadership responsibilities inexplaining complications of chemotherapy topatientsd2- upgrade his scientific information utilizingall available printed and electronic sources tomanage side effects of chemotherapy
Course Content(Units/Topics)
Teaching/Learning MethodsLectures self
learningPractical/Clinical
Smallgroupdiscussion
Others
Non Hodgkin's lymphomas. Classifications. Epidemiology. Aetiology. Cytogenetics& oncogenes. Clinical features. Investigations. Staging. Treatment. Specific types.
Hodgkin's lymphoma: Epidemiology. Classification. Pathogenesis. Presentation. Staging. Prognostic factors. Therapy.
Please check () the appropriate method.
Student AssessmentMethods of Assessment Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment Mid-term %
End of term 100 %Distribution of Marks Written Exam 70 %
Practical/Clinical Exam 30 %Others %
List of Textbooks and ReferencesLecture Notes Print out of lectures
Course Text Books Postgraduate haematology
Suggested Extra Reading William haematology
Journals and Periodicals, others Bloodhaematologica
Course InstructorName: Prof. Nabil El-Halawani
Program CoordinatorName : Nahla Hamed Signature:
Program Director (Head of Department)Name: Prof . Signature: Yehia Ghanem
Course Specifications
University: Alexandria
Faculty: Medicine
Department:Internal Medicine- Hematology Unit
Course InformationCourse Code:
05151912Course Name: stem cell transplantation
Program in which the Course is Given: MD in hematology
Number of Credit Hours2Theoretical Clinical/Practical
Course Aimsto provide candidates with the basic knowledge about the indications of HSCtransplantation, stem cell sources, pre transplant evaluation, and management during the transplantprocedure and post transplant complications.Intended Learning Outcomes (ILOs)
Program ILO (refer to programmatrix)
Course ILOs
A. KnowledgeandUnderstanding
-Understanding recent advances inthe classification , pathogenesis,molecular biology , diagnosis andtherapeutic modalities ofhematological diseases.
Identify recent advances in the field of HSCtransplantation regarding indications,selection of patients, pre-transplantevaluation, the transplant procedure andpost-transplant complications.
B. Intellectualskills
-Analysis and interpretation ofclinical data and laboratory resultsof various hematologicaldisorders.-Decision making in the diagnosisand appropriate treatment planningof hematological diseases which isevidence-based.
-How to select patients for the transplantprocedure according to indications,comorbidities, laboratory data andassessment of benefit/risk ratio.-Analysis of clinical and laboratory data ofpatients during and post-transplantation andsuggestion of appropriate measures to betaken accordingly.
C.Professionaland PracticalSkills
-Improving the professional skillsneeded for treatment of varioushematological disorders, includingexperience with use ofchemotherapy protocols andmanagement of side effects.
-Appropriate management of patients before,during the procedure and in the post-transplant period according to recentguidelines.-How to monitor and deal with the adverseeffects of conditioning regimens and othermedications used during and aftertransplantation.
0.51.5shrs
D. GeneralSkills
-Development and improvementof communication andleadership skills.
-To enhance communication skills with boththe medical team and the patients.
Course Content(Units/Topics)
Teaching/Learning MethodsLectures self
learningPractical/Clinical
Smallgroupdiscussion
Others
Overview of HSCT Stem cell sources Pre-transplant evaluation Conditioning regimens and supportivecare
GVHD prophylaxis Transfusion medicine Engraftment
Infectious Complications Acute GVHD Chronic GVHD Thrombotic Microangiopathies Graft Failure Post-transplant Relapse
Please check () the appropriate method.
Student AssessmentMethods of Assessment Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment Mid-term ---
End of term 100%Distribution of Marks Written Exam 80 %
Practical/Clinical Exam --
Others log book+assignment20%
List of Textbooks and ReferencesLecture Notes -Lecture Notes
Course Text Books -Postgraduate Hematology
Suggested Extra Reading -Blood and Marrow Transplant Handbook-The EBMT Handbook
Journals and Periodicals, others
Course InstructorName: Prof.Manal El SoradySignature: Manal El Sorady
Program CoordinatorName: Prof. Nahla HamedSignature:
Program Director (Head of Department)Name: Prof . Manal El SoradySignature: Manal El Sorady
Course Specifications
University: Alexandria
Faculty: Medicine
Department:
Course InformationCourse Code:
05151911Course Name: Immune deficiencies
Program in which the Course is Given: doctorate program in hematology
Number of Credit Hours 1 Theoretical Clinical/Practical
Course Aimsprovide updated knowledge and skills that allow Dealing successfully with common and difficult cases withdiseases of blood and bone marrow as well as Interpret hematological manifestations of medical diseasesand solid tumors.
Intended Learning Outcomes (ILOs)Program ILO (refer to programmatrix)
Course ILOs
A. KnowledgeandUnderstanding
Identify Recent advances inthe field of diagnosis andmanagement of haematologicaldiseases including anaemia,coagulation disturbance andhaematological malignancies.
a11– update his knowledge on the impact ofsystemic disease on the blood and bone marrow.
B. Intellectualskills
Analyze, deduce, extrapolate &evaluate laboratory informationto establish diagnosis andappropriate treatment planning.
b1 Analyze laboratory testing results for theinitial management of common and unusualhematological disorders.
b2 Take decision in the diagnosis andappropriate treatment planning.
b4 apply multidisciplinary team work formanaging complication
C.Professionaland PracticalSkills
c1 Plan professional courses toimprove practice and enhanceperformance of juniors asregards
c2Plan professional courses for appropriateuse of antibiotic regimens for treatmentand prophylaxis in the immunosuppressedpatient.
appropriate use of antibioticregimens for treatment andprophylaxis inimmunosuppressed patient.
D. GeneralSkills
Communicate with colleagues inother specialties effectively forproper diagnosis and treatmentof the patients.
-Advance his knowledge andinformation continuously usingdifferent printed and electronicsources.
d3-Communicate effectively with colleagues inother specialties for proper management of thepatients.d6-perform continuous self lifelong learningd7-Upgrade his scientific knowledge utilizing all
available sources.
Course Content (Units/Topics)
Teaching/Learning MethodsLectures self
learningPractical/Clinical
Smallgroupdiscussion
Others
Hereditary immunodeficiency Acquired immunodeficiency
Please check () the appropriate method.
Student AssessmentMethods of Assessment Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment Mid-term %
End of term 100 %
Distribution of Marks Written Exam 100 %Practical/Clinical Exam %Others %
List of Textbooks and ReferencesLecture Notes Print out
Course Text Books Postgraduate haematology
Suggested Extra Reading William haematology
Journals and Periodicals, others BloodHaematologica
Course InstructorName: Prof. Dr Manal sorady
Prof.Dr ashraf alghandour Signature:
Program CoordinatorName: Prof.Dr. Nahla A. Hamed Signature:
Program Director (Head of Department)Name: Prof . Dr. Hassan Nafea Signature:
Course Specifications
University: Alexandria
Faculty: Medicine
Department:
Course InformationCourse Code:
05151913Course Name: Integrated hematology II
Program in which the Course is Given: MD in hematology
Number of Credit Hours 4 Theoretical Clinical/Practical
Course Aimsprovide candidates with the updated skills that allow them to Deal successfully with common and difficultcases with diseases of blood and bone marrow as well as Interpret hematological manifestations ofmedical diseases and solid tumors.
Intended Learning Outcomes (ILOs)Program ILO (refer to programmatrix)
Course ILOs
A. KnowledgeandUnderstanding
B. Intellectualskills
Analyze, deduce, extrapolate &evaluate laboratory informationto establish diagnosis andappropriate treatment planning.
Take decisions in variousprofessional situations ofhaematological problemsaccording to the available data
Apply evidence based medicinefrom updated reference.
b1 Analyze laboratory testing results for theinitial management of common and unusualhematological disorders.
b2 Take decision in the diagnosis andappropriate treatment planning.
b3 Explain planned treatment clearly to juniorstaff
b5 Apply evidence based medicine fromupdated printed and electronic reference.
C.Professionaland PracticalSkills
D. GeneralSkills
Communicate with colleagues inother specialties effectively forproper diagnosis and treatmentof the patients.
Write and assess patient’sreports
-Advance his knowledge andinformation continuously usingdifferent printed and electronicsources.
d3-Communicate effectively with colleagues inother specialties for proper management of thepatients.d4-Perform leadership responsibilitiesd5- Write and appraise reports.d6-perform continuous self lifelong learningd7-Upgrade his scientific knowledge utilizing all
available sources.
Course Content (Units/Topics)
Teaching/Learning MethodsLectures self
learningPractical/Clinical
Smallgroupdiscussion
Others
Please check () the appropriate method.
Student AssessmentMethods of Assessment Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment Mid-term %
End of term 100 %Distribution of Marks Written Exam %
Practical/Clinical Exam 100 %Others %
List of Textbooks and ReferencesLecture Notes
Course Text Books Postgraduate haematology
Suggested Extra Reading William haematology
Journals and Periodicals, others Bloodhaematologica
Course InstructorName: Prof. Dr Manal sorady
Prof.Dr ashraf alghandour Signature:
Program CoordinatorName: Prof.Dr. Nahla A. Hamed Signature:
Program Director (Head of Department)Name: Prof . Dr. Hassan Nafea Signature:
Course Specifications
University: Alexandria
Faculty: Medicine
Department:
Course InformationCourse Code:
05151907Course Name:myeloma II
Program in which the Course is Given: MD in hematology
Number of Credit Hours 2 Theoretical Clinical/Practical
Course Aimsto provide candidates with the updated knowledge and skills that allow themtodiagnose and manage successfully Myeloma
Intended Learning Outcomes (ILOs)Program ILO (refer to programmatrix)
Course ILOs
A. KnowledgeandUnderstanding
a1 – Identify Recent advances inthe field of molecular biologyin myeloma
a2 Identify recent advanes indiagnosis and management ofMyeloma
a5 – Identify recent advances in theclassification, natural history, molecularbiology, and therapeutic modalities ofhematological malignancies.
B. Intellectualskills
b1 Analyze & evaluate availablelaboratory information toestablish treatment plan ofMyeloma.
b2 Analyze & deduce laboratorytests to establish treatment ofuncommon types of Myeloma.
b4 Solve professional problemsrelated to Myeloma accordingto the available data
b5 Refer to evidence basedmedicine in managing cases
b6 Refer to updated reference indealing with difficult cases.
b1 Analyze, deduce, extrapolate & evaluatelaboratory testing results for the initialmanagement of common and unusualhematological disorders.
b2 Take decision in the diagnosis andappropriate treatment planning.
b5 Apply evidence based medicine fromupdated printed and electronic reference.
11
C.ProfessionalandPractical Skills
C1-Evaluate and improve methodsand tools used in management ofMyelomaC2–Plan professional courses to
improve practice and enhanceperformance of juniors asregards appropriate treatmentof Myeloma
C1-Plan professional courses of combinationchemotherapy regimens
D. General Skills d1-Perform leadershipresponsibilities in explainingcomplications of chemotherapy topatientsd2- upgrade his scientificinformation utilizing all availableprinted and electronic sources tomanage side effects ofchemotherapy
d1-perform full explanation of the sideeffects of chemotherapy to patients.
Course Content(Units/Topics)
Teaching/Learning MethodsLectures self
learningPractical/Clinical
Smallgroupdiscussion
Others
Myeloma: Definition. Pathogenesis. Clinical features. Laboratory findings. Treatment. Monoclonal gammopathy of
uncertain significance.
Special types of myeloma: Plasma cellleukemia. Non-secretory myeloma.
Waldenstrommacroglobulinaemia. Heavy-chain diseases.
Please check () the appropriate method.
Student AssessmentMethods of Assessment Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment Mid-term %
End of term 10 %Distribution of Marks Written Exam 70 %
Practical/Clinical Exam 30 %Others %
List of Textbooks and ReferencesLecture Notes Print out of lectures
Course Text Books Postgraduate haematology
Suggested Extra Reading William haematology
Journals and Periodicals, others Bloodhaematologica
Course InstructorName: Prof. Nahla AM Hamed Signature: Nahla AM Hamed.
Program Director (Head of Department)Name: Prof . Signature: YehiaGhanem
Course Specifications
University: Alexandria
Faculty: Medicine
Department:Internal Medicine
Course InformationCourse Code: 05151909 Course Name:Hematological Manifestations of
Medical Diseases IIProgram in which the Course is Given Doctorate Degree in Hematology
Number of Credit Hours 2 Theoretical Clinical/Practical
Course Aimsto provide candidates with the updated knowledge and skills that allow them todiagnose
Hematological Manifestations of Medical Diseases
Intended Learning Outcomes (ILOs)Program ILO(refer to programmatrix)
Course ILOs
A. KnowledgeandUnderstanding
a11 – update his knowledge on theimpact of systemic disease on theblood and bone marrow.
a12 – update his knowledge inhaemostatic problems inpregnancy and solid tumors
a1 – Identify Recent advances in the diagnosisof Hematological Manifestations ofMedical Diseases
a2 Identify recent advances in treatinghaematological manifestations of medicaldisorders
a3 Identify updated knowledge inhaematological changes accompanyingsolid tumors
a4 Identify recent data in diagnosis andmanagement of haematologicalabnormalities during pregnancy
B. Intellectualskills
b4 apply multidisciplinary team workfor managing complication
b1 Communicates with his collagues in otherspeciality for early detection ofcomplications of Medical Diseases.
b2 Work in multidisciplinary team for bestresults in treatment of haematologicalmanifestations of systemic disease
11
C.Professionaland PracticalSkills
c2 – Plan professional courses forappropriate use of antibioticregimens for treatment andprophylaxis in theimmunosuppressed patient.
C1-plan professional course for use ofantibiotics in cancer patientsC2- plan for professional course for treatinginfection in HIV
D. GeneralSkills
d3- Communicate effectively withcolleagues in other specialties forproper diagnosis and treatment ofthe patients.
d1- Communicate with different specialties atoptimum time for proper managing of thepatients.d2- Write and appraise reports
Course Content(Units/Topics)
Teaching/Learning MethodsLectures self
learningPractical/Clinical
Smallgroupdiscussion
Others
Hematological Manifestations ofConnective tissue disorders
Hematological Manifestations of liverdisease
Hematological Manifestations of renaldisease
Hematological Manifestations ofendocrine disease
Please check () the appropriate method.
Student AssessmentMethods of Assessment Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment Mid-term %
End of term 100 %Distribution of Marks Written Exam 70 %
Practical/Clinical Exam 30 %Others %
List of Textbooks and ReferencesLecture Notes Print out of lectures
Course Text Books Postgraduate haematology
Suggested Extra Reading William haematology
Journals and Periodicals, others Bloodhaematologica
Course InstructorName: Prof. Nahla AM Hamed Signature: Nahla AM Hamed
Program CoordinatorName: Prof. Nahla AM Hamed Signature: Nahla AM Hamed
Program Director (Head of Department)Name: Prof. Yehia Ghanem Signature: Yehia Ghanem
Course Specifications
University: Alexandria
Faculty: Medicine
Department:Internal Medicine
Course InformationCourse Code: 05151903 Course Name: Acute Leukaemias IIProgram in which the Course is Given Doctorate Degree in Hematology
Number of Credit Hours Theoretical Clinical/Practical
Course Aimsto provide candidates with the updated knowledge and skills that allow them to diagnose and
manage successfully acute leukaemic patients
Intended Learning Outcomes (ILOs)Program ILO(refer to programmatrix)
Course ILOs
A. KnowledgeandUnderstanding
a4 Identify recent advances indiagnosis, classification andmanagement of acute andchronic leukemias in adults.
a13 update his knowledge regardingindications and management ofbone marrow transplantation
a1 – Identify Recent advances in moleculardiagnosis of acute leukaemia
a2 Identify Recent advances in prognosticfactors and their relation tomananagement
a3 –update his data concerning indication ofbone marrow transplantation
a4 –update his knowledge regardingposttransplant immunosuppressive drugs
B. Intellectualskills
b3 Explain planned treatmentclearly to junior staff
b1 Take decisions in treatment plan ofpatients
b2 Explain planed treatment and their sideeffects to other team member
C.ProfessionalandPractical Skills
c2 Plan professional courses forappropriate use of antibioticregimens for treatment andprophylaxis in theimmunosuppressed patient.
C1-Evaluate and improve uses of antibioticduring period of aplasiaC2–Plan professional courses to improvepractice and enhance performance of juniorsas regards appropriate use of antibioticduring aplasia
11
c5 – Evaluate and improvemethods and tools used instem cell transplantation
c6 - Evaluate and improvemethods and tools used indiagnosis & management ofhematological emergencies.
C3-Plan professional courses to improvemethods used in managing complications ofstem cell transplantationC4-evaluate and improve protocols used instem cell transplantation
C5-- Evaluate and improve diagnosticmethods of hematological emergencies
C6-plan professional courses formanagement of haematologicalemergencies
D. General Skills d2-communicates effectively withpatients performing transplantationand their family.
d4-Perform leadershipresponsibilities
d5- Write and appraise reports.
d1- Communicate with patients indicatedfor bone marrow transplantation as well astheir familiesd2- describe complications of bone marrowtransplantation to patients
d3-describe detailed follow up for junior staffd4- assess jobs ascribed to nursing staff
d3- Write referral medical reports.d4- assess medical reports written by juniorstaff
Course Content(Units/Topics)
Teaching/Learning MethodsLectures self
learningPractical/Clinical
Smallgroupdiscussion
Others
Acute myeloid leukemia. Epidemiology of disease. Pathophysiology. Disease classification. Cytogenetics. Treatment. Future developments.
Adult acute lymphoblastic leukaemia: Introduction. Diagnosis. Clinical manifestations. Laboratory evaluation. Differential diagnosis. Initial evaluation and supportive
therapy. Chemotherapy. Stem Cell transplantation. Outcome of all subtypes and
prognostic factors. Minimal residual disease-practical
application in adult ALL. Treatment with monoclonal
antibodies. ABL tyrosine kinaseinhibitors in Ph/BCR-ABL-positiveALL.
Please check () the appropriate method.
Student AssessmentMethods of Assessment Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment Mid-term %
End of term 100 %Distribution of Marks Written Exam 70 %
Practical/Clinical Exam 30 %Others %
List of Textbooks and ReferencesLecture Notes Print out of lectures
Course Text Books Postgraduate haematology
Suggested Extra Reading William haematology
Journals and Periodicals, others Bloodhaematologica
Course InstructorName: Prof. Hashim neanaa Signature:
Program CoordinatorName: Prof. Nahla AM Hamed Signature:
Program Director (Head of Department)Name: Prof. Yehia Ghanem Signature: Yehia Ghanem
Course Specifications
University: Alexandria
Faculty: Medicine
Department:Internal Medicine
Course InformationCourse Code: 05151902 Course Name: Iron Metabolism, Iron Deficiency
and Disorders of Haem Synthesis,MegaloblasticAnaemia,HaemolyticAnaemias, Aplastic
Anaemia
Program in which the Course is GivenDoctorate Degree in Hematology
Number of Credit Hours 4 Theoretical Clinical/Practical
Course Aimsto provide candidates with the updated knowledge and skills that allow them to Diagnose and
manage successfully anaemic patients
Intended Learning Outcomes (ILOs)Program ILO(refer to programmatrix)
Course ILOs
A. KnowledgeandUnderstanding
a1 – Identify recent advances in thecauses, presentation,complications, diagnosis andmanagement of different types ofanemia.
a1 – Identify Recent advances in genetic basisof thalassaemia
a2 Update his knowledge in the field ofdiagnosis of anaemia
a3 Update his knowledge in management ofdifferent types of anaemia
a4 Update his knowledge regarding treatmentof paroxysmal nocturnal haemoglobinuria
a5 –update his knowledge regarding recentdrugs used in the field of anaemia
a6 Update his knowledge in the use ofhydroxyurea
a7 Update his knwoldge regarding screeningfor thalassemia
a8 Update his knowledge regarding druginduced haemolytic anaemia
a9 Identify recent advances in Molecularmechanisms of normal iron
a10– identify recent advances in invasive
13
a3 – Identify recent advances indiagnosis and management ofinherited and acquired bonemarrow failure.
assessment of tissue iron overloada11Update his knowledge in the use of
iron chelation therapy
a12Update his data in use ofimmunosuppressive therapy in aplasticanaemia
a13Update his knowledge in use of bonemarrow transplantation in aplasticanaemia
B. Intellectualskills
b5 Apply evidence based medicinefrom updated printed andelectronic reference.
b1 Take decisions in various professionalsituations related to anaemic patientsaccording to evidence based medicine
b2 Solve advanced problems related totreatment of sickle cell anaemia
b3 Solve advanced problems related todiagnosis of pancytopenia
b4 Take decisions in treatment of infections inaplastic anaemia
b5 Solve problems related to diagnosis of ironoverload
C.Professionaland PracticalSkills
c5 – Evaluate and improvemethods and tools used in stemcell transplantation
c6 - Evaluate and improvemethods and tools used indiagnosis & management ofhematological emergencies.
C1-evaluate the tools used in use of bonemarrow transplantation in thalassaemia
C2-evaluate and improve methods use intransplanting hepatitis c positive patients
C3-improve methods used in preventingsickle cell crisisC4- improves methods used in treatingsickle cell crisis
D. GeneralSkills
d6-perform continuous self lifelonglearning
d7-Upgrade his scientific knowledgeutilizing all available sources
d1-perform self learning all through his lifed2- Plan courses for junior staffd3-shares in scientific conferences
d4-Upgrade his scientific knowledgecontinuously using available printed sourcesd5- perform updating his knowledge throughelectronic sources.d5-perform researches in his field
Course Content(Units/Topics)
Teaching/Learning MethodsLectures self
learningPractical/Clinical
Smallgroupdiscussion
Others
Distribution of body iron. Cellular ironhomeostasis. Normal iron balance. Ironabsorption. Internal exchange. Diagnosticmethods for investigating iron metabolism.
Iron deficiency anaemia. Causes of iron deficiency. Management of iron deficiency.
Haem synthesis. Pathological alterations inhaem synthesis.
Megaloblasticanaemia: Introduction. Underlying basic science. Clinical features. Haematological findings. Cobalamin. Cobalamin analogues. Causes of cobalamin deficiency. Diagnosis of cobalamin deficiency.
Tests for the cause of cobalamindeficiency.
Folate. Causes of folate deficiency. Diagnosis of folate deficiency. General management of
megaloblasticanaemia.Prophylactic folic acid.
Megaloblasticanaemia not due tocobalamin or folate deficiency oraltered metabolism.
Other nutritional anaemias.
Haemolyticanaemias Disorders of red cell membrane. Inherited disorders of hemoglobin.
Sickle cell disease. Acquired haemolyticanaemias Immune haemolyticanaemias.
Warm-type autoimmunehaemolyticanaemias. Cold-typeautoimmune haemolyticanaemias.
The non-immune acquiredhaemolyticanaemias.
Inherited aplastic anaemia/bone marrowfailure syndromes:
Introduction.
Fanconianaemia. Dyskeratosiscongenital. Shwachman-Diamondsyndrome. Diamond-Blackfananaemia.
Congenital and cyclicalneutropenias.
Thrombocytopenia with absentradii. Congenital amegakaryocyticthrombocytopenia.
PNHAcquired aplastic anaemiaPlease check () the appropriate method.
Student AssessmentMethods of Assessment Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment Mid-term %
End of term 100 %Distribution of Marks Written Exam 70 %
Practical/Clinical Exam 30 %Others %
List of Textbooks and ReferencesLecture Notes Print out of lectures
Course Text Books Postgraduate haematology
Suggested Extra Reading William haematology
Journals and Periodicals, others Bloodhaematologica
Course InstructorName: Prof. Hassan Nafea
Hassan Nafea
Program CoordinatorName: Prof. Nahla AM Hamed
Nahla AM Hamed
Program Director (Head of Department)Name: Prof. Yehia Ghanem
Yehia Ghanem
Course Specifications
University: Alexandria
Faculty: Medicine
Department: Internal Medicine
Course InformationCourse Code: 05151909 Course Name: Blood Transfusion II
Program in which the Course is Given Doctorate Degree in Hematology
Number of Credit Hours 2 Theoretical Clinical/Practical
Course Aimsto provide candidates with the Recent advances inthe field of blood transfusion
Intended Learning Outcomes (ILOs)Program ILO(refer to programmatrix)
Course ILOs
A. KnowledgeandUnderstanding
a8 – update his knowledge in thepharmaceuticals and bloodproducts available for themanagement of excessivebleeding.
a9 – update his knowledge in thefield of blood transfusion.
a1 – Identify Recent advances in the indicationof blood transfusion.
a2 Identify recent advances in managingcomplications of blood transfusion
a3 Identify recent advances in Transfusion-Related Acute Lung Injury
a4 –update his knowledge in artificial plateletsubstitutes
a5 Identify recent advances in therapeuticapheresis
a6 Update his knowledge in alternative to bloodtransfusion
a7 Update his knowledge in use of anti Da8 Update his knowledge in platelet
refractorinessB. Intellectualskills
b2 Take decision in the diagnosis andappropriate treatment planning.
b1- take decision in early diagnosis ofcomplications of blood transfusionb2- take decision in treatment ofcomplication of blood transfusion
2
C.Professionaland PracticalSkills
C3-Plan professional courses forcomplications of blood transfusionappropriately
C1-Plan advanced courses for junior staffconcerning management of complications ofblood transfusionC2-solve problems related to complications ofblood transfusion
D. GeneralSkills
Course Content(Units/Topics)
Teaching/Learning MethodsLectures self
learningPractical/Clinical
Smallgroupdiscussion
Others
Blood component transfusion indications Complications of blood transfusion Alternative to blood transfusionTherapeutic apheresis
Please check () the appropriate method.
Student AssessmentMethods of Assessment Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment Mid-term %
End of term 100 %Distribution of Marks Written Exam 100 %
Practical/Clinical Exam %Others %
List of Textbooks and ReferencesLecture Notes Print out of lectures
Course Text Books Postgraduate haematology
Suggested Extra Reading William haematology
Journals and Periodicals, others Bloodhaematologica
Course InstructorName: Ass. Prof. Nadia Zaki Signature:
Program CoordinatorName: Prof. Nahla AM Hamed Signature:
Program Director (Head of Department)Name: Prof. Yehia Ghanem Signature: Yehia Ghanem
Course Specifications
University: Alexandria
Faculty: Medicine
Department:Internal Medicine
Course InformationCourse Code: 05151908 Course Name: Homeostasis IIProgram in which the Course is GivenDoctorate Degree in Hematology
Number of Credit Hours 3 Theoretical Clinical/Practical
Course Aimsto provide candidates with the updated knowledge and skills that allow them todiagnose and manage
successfully haemostatic disorders
Intended Learning Outcomes (ILOs)Program ILO(refer to programmatrix)
Course ILOs
A. KnowledgeandUnderstanding
a7 – Identify recent advances in thediagnostic methods used in theassessment and themanagement congenitalcoagulation and plateletdisorders.
a8 – update his knowledge in thepharmaceuticals and bloodproducts available for themanagement of excessivebleeding.
a1 – Identify Recent advances in the field ofdiagnosis of haemostasis
a2 Identify updated knowledge in themanagement of haemostatic disorders
a3 Updating his knowledge regardingtreatment of von Willebrand diseaseaccording to molecular data
a4 –update his knowledge regarding the drugsused in the field of haemostatic disorders
a5 Update his knowledge in indication andside effects of blood products
a6 Update his data regarding management ofbleeding disorders during pregnancy
a7 Identify recent advances in drug inducedthrombocytopenia
B. Intellectualskills
b1 Analyze, deduce, extrapolate &evaluate laboratory testingresults for the initialmanagement of common andunusual hematological disorders.
b2 Take decision in the diagnosis
b1 Analyze & evaluate laboratory data to planfor treating platelet disorders
b2 Analyze & evaluate results of laboratorytests to treat coagulation abnormalities
b3 Take decisions in various professional
12
and appropriate treatmentplanning.
b5 Apply evidence based medicinefrom updated printed andelectronic reference.
situations of haemostatic disordersb4 solve problems related to haemostatic
disorders according to the available data
b5 Apply treatment according to evidence basedmedicine
b6 Refer to updated referencein rarepresentations
C.ProfessionalandPractical Skills
c4 – Plan professional coursesfor use and monitoring ofanticoagulation
C1-Evaluate and improve methods and toolsused in management of haemostatic disordersC2–Plan professional courses to improve
practice and enhance performance ofjuniors as regards appropriate treatment ofhaemostatic disordersand monitoring ofanticoagulants
D. General Skills d7-Upgrade his scientific knowledgeutilizing all available sources.
d1- Upgrade his scientific data using recenttextbooks and journals.d2- select appropriate idea for research work
Course Content(Units/Topics)
Teaching/Learning MethodsLectures self
learningPractical/Clinical
Smallgroupdiscussion
Others
Normal haemostasis: Blood vessels.Platelets. Coagulation factors. Naturallyoccurring inhibitors. Fibrinolysis.
Inherited bleeding disorders: Haemophilia A. Haemophilia B. Gene therapy. Von Willibrand disease. Congenital platelet disorders
Acquired coagulation, platelet & vascularbleeding:
Disseminated intravascularcoagulation.
Coagulopathy & massive bloodloss.
Vitamin K deficiency. Idiopathic
thrombocytophricpurpura. vascularpurpuras.
Inherited thrombophilia.. Acquired venous thrombosis. TTP. Please check () the appropriate method.
Student AssessmentMethods of Assessment Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment Mid-term %
End of term 100 %Distribution of Marks Written Exam 70 %
Practical/Clinical Exam 30 %Others %
List of Textbooks and ReferencesLecture Notes Print out of lectures
Course Text Books Postgraduate haematology
Suggested Extra Reading William haematology
Journals and Periodicals, others Bloodhaematologica
Course InstructorName: Prof. Mohamed El-Dafrawy Signature:
Program CoordinatorName: Prof. Nahla AM Hamed
Program Director (Head of Department)Name: Prof. Yehia Ghanem
Course Specifications
University: Alexandria
Faculty: Medicine
Department: Internal Medicine
Course InformationCourse Code: 05151901 Course Name: Haemopoiesis II
Program in which the Course is GivenDoctorate Degree in Hematology
Number of Credit Hours 2 Theoretical Clinical/Practical
Course Aimsto provide candidates with the Recent advances inthe field of stem cells research
Intended Learning Outcomes (ILOs)Program ILO(refer to programmatrix)
Course ILOs
A. KnowledgeandUnderstanding
a2 Identify recent advances in stemcell research.
a1 – Identify Recent advances in the field ofstem cells.
a2 –update his knowledge regarding growthfactors
a3 Identify recent advances in therapeutic usesof haematopoeitic growth factor
a4 Update his knowledge in T lymphopoiesisa5 – Identify recent advances in B cell
development.a6 Update his knowledge in cytokinesa7 Update his knowledge in therapeutic
implication of cytokinesa8 Identify recent advances in complications
of use of erythropoietina9 Update his knowledge in signal
transduction pathwaysa10Update his knowledge in cell surface
markersB. Intellectualskills
b3 Explain planned treatment clearlyto junior staff
b1- explain use of myeloid growth factors inimmunosuppressed patients to junior staffb2- discuss recent indications of
2
erythropoietin to junior staff
C.Professionaland PracticalSkills
D. GeneralSkills
Course Content(Units/Topics)
Teaching/Learning MethodsLectures self
learningPractical/Clinical
Smallgroupdiscussion
Others
Introduction Sites of haemopoiesis The stromal microenvironment Stem cell trafficking Organization of haemopoiesis Haemopoietic growth factors andreceptors
Clinical applications of stem cellresearch.
Please check () the appropriate method.
Student AssessmentMethods of Assessment Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment Mid-term %
End of term 100 %Distribution of Marks Written Exam 100 %
Practical/Clinical Exam %Others %
List of Textbooks and ReferencesLecture Notes Print out of lectures
Course Text Books Postgraduate haematology
Suggested Extra Reading William haematology
Journals and Periodicals, others Bloodhaematologica
Course InstructorName: Prof. Manal Elsorady
Program CoordinatorName: Prof. Nahla AM Hamed
Program Director (Head of Department)Name: Prof. Yehia Ghanem
Course Specifications
University: Alexandria
Faculty: Medicine
Department:Internal Medicine
Course InformationCourse Code: 05151905 Course Name: Stem Cell Disorders IIProgram in which the Course is Given Doctorate Degree in Hematology
Number of Credit Hours 3 Theoretical Clinical/Practical
Course Aimsto provide candidates with the updated knowledge and skills that allow them todiagnose and
manage successfully stem cell disorders
Intended Learning Outcomes (ILOs)Program ILO(refer to programmatrix)
Course ILOs
A. KnowledgeandUnderstanding
a10 – update his knowledge inclassification of myeloproliferativedisorders, the required diagnosticmethods and the therapeuticoptions.
a1 – Identify Recent advances in the field ofdiagnosis and management of stem celldisorders
a2 –update his knowledge regarding the drugsused in the field of stem cell disorders
B. Intellectualskills
b1 Analyze, deduce, extrapolate &evaluate laboratory testing resultsfor the initial management ofcommon and unusualhematological disorders.
b1 Analyze & evaluate laboratory informationto establish diagnosis and appropriatetreatment planning of unusual stem celldisorders.
b2 Take decisions in various professionalsituations of problems related to stemcell disorders according to the availabledata
C.Professionaland PracticalSkills
c1 - Plan professional courses ofcombination chemotherapyregimens.
C1-Evaluate and improvemethods and toolsused in management of stem cell disordersC2–Plan professional courses to improvepractice and enhance performance of juniorsas regards appropriate treatment of stem celldisorders
12
D. GeneralSkills
d7-Upgrade his scientific knowledgeutilizing all available sources.
d1- update his data using available journalsof the specialityd2- update his knowledge in treatmentutilizing all related web sites
Course Content(Units/Topics)
Teaching/Learning MethodsLectures self
learningPractical/Clinical
Smallgroupdiscussion
Others
Myelodysplastic syndromes. Cytogenetics. Investigations. Classifcation. Pathogenesis. Prognosis. Management.
Myeloproliferative disorders: The polycythaemia. Polycythaemia rubra vera. Essential thrombocythaemia. Idiopathic myelofibrosis.
Please check () the appropriate method.
Student AssessmentMethods of Assessment Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment Mid-term %
End of term 100 %Distribution of Marks Written Exam 70 %
Practical/Clinical Exam 30 %Others %
List of Textbooks and ReferencesLecture Notes Print out of lectures
Course Text Books Postgraduate haematology
Suggested Extra Reading William haematology
Journals and Periodicals, others Bloodhaematologica
Course InstructorName: Prof. Nahla AM Hamed
Program CoordinatorName: Prof. Nahla AM Hamed
Program Director (Head of Department)Name: Prof. Yehia Ghanem
Course Specifications
University: Alexandria
Faculty: Medicine
Department:Internal Medicine
Course InformationCourse Code: 05151904 Course Name: Chronic Leukaemias IIProgram in which the Course is Given Doctorate Degree in Hematology
Number of Credit Hours 2 Theoretical Clinical/Practical
Course Aimsto provide candidates with the updated knowledge and skills that allow them todiagnose and
manage successfully chronicleukaemicpatients
Intended Learning Outcomes (ILOs)Program ILO(refer to programmatrix)
Course ILOs
A. KnowledgeandUnderstanding
a4 – Identify recent advances indiagnosis, classification andmanagement of acute andchronic leukemias in adults.
a14– update his knowledgeregarding chemotherapyregimens used in themanagement of hematologicalmalignancies.
a1 – Identify Recent advances in thediagnosis of minimal residual disease inchronic lymphocytic leukaemia
a2 Update his knowledge in therapeutic planin chronic myeloid leukaemia
a3 –update his data in the recent drugs usedin chronic myeloid leukaemia
a4 Identify recent advances in indications andside effects of classes of tyrosine kinases
B. Intellectualskills
b1 Analyze, deduce, extrapolate &evaluate laboratory testingresults for the initialmanagement of common andunusual hematological disorders.
b1 Analyze, deduce, extrapolate & evaluatelaboratory information to establishdiagnosis
b2 Plan for appropriate treatment of chronicleukaemic patients.
b3 Take decisions in various professionalsituations of problems related tochronic leukaemia according to theavailable data
b4 Apply evidence based medicine fromupdated reference.
11
C.ProfessionalandPractical Skills
c1 - Plan professional courses ofcombination chemotherapyregimens.
c2 – Plan professional coursesfor appropriate use ofantibiotic regimens fortreatment and prophylaxis inthe immunosuppressedpatient.
C1- plan professional course forguidelines in treating chronic myeloidleukaemia
C2- plan professional course for updatedtherapy in chronic lymphocyticleukaemia
C3- plan for professional courses fortreatm ent of immunosuppression onfludarabine therapy
C4-plan for professional courses fortreatment of immunosuppression inchronic lymphocytic leukaemia
D. General Skills d1- perform full explanation of theside effects of chemotherapy topatients.
d5- Write and appraise reports.
d1- Perform explanation of side effects oftyrosine kinases to patientsd2-perform explanation of side effects offludarabine to the patients
d3- Write and judge medical reportsefficientlyd4-select the appropriate time for referal
Course Content(Units/Topics)
Teaching/Learning MethodsLectures self
learningPractical/Clinical
Smallgroupdiscussion
Others
chronic myeloid leukaemia Introduction. Classification. Cytogenetics. Molecular biology. Clinical features. Haematology. Management :Treatment decisions
for newly diagnosed patients inchronic phase. Management ofchronic myeloid leukaemia inadvanced phase.
Variants of chronic myeloidleukaemia.
Chronic lymphocytic leukaemia and other
B-cell disorders: Introduction. Methodology for diagnosis.
Chronic lymphocytic leukaemia.Management.
Prolymphocyticleukaemia.
Hairy cell leukaemia. The leukaemic phase of low-grade NHL. Please check () the appropriate method.
Student AssessmentMethods of Assessment Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment Mid-term %
End of term 100 %Distribution of Marks Written Exam 70 %
Practical/Clinical Exam 30 %Others %
List of Textbooks and ReferencesLecture Notes Print out of lectures
Course Text Books Postgraduate haematology
Suggested Extra Reading William haematology
Journals and Periodicals, others Bloodhaematologica
Course InstructorName: Prof. Hashim Naenaa
Program CoordinatorName: Prof. Nahla AM Hamed
Program Director (Head of Department)Name: Prof. Yehia Ghanem