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Update on TG 147: QA for non- radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby

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Page 1: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Update on TG 147: QA for non-radiographic localization and

positioning systems

AAPM Anaheim, CA 2009Twyla Willoughby

Page 2: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Thank-You

Joerg Lehmann, Ph.D.: TG Co-ChairRadiological Associates of

Sacramento

José A. Bencomo, Ph.D.US Oncology

Shirish K. Jani, Ph.D.Sharp Metropolitan Medical Campus

Lakshmi Santanam, Ph.D.Washington University

Anil Sethi, Ph.D.Loyola University Medical Center

Timothy D. Solberg, Ph.D.UT Southwestern Medical Center

Wolfgang A. Tomé, Ph.D.University of Wisconsin

School of Medicine and Public Health

Tim Waldron, M.S.University of Iowa

Page 3: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

IGRT• Ultrasound: Soft tissue alignment – mostly

prostate• Orthogonal MV x-rays: Bony anatomy or implanted

markers• Orthogonal kV x-rays: Bony anatomy or implanted

markers• Cone-beam CT: image quality may be an issue• MV CT: Image quality may be a concern• In room CT: Good image quality not exactly same

treatment position• Other: Video, RF, and laser alignment systems

Page 4: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Disclaimer

• Task Group Report has NOT beenapproved as of yet.

• Projected publication date: Late2009/Early 2010

Page 5: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

What is Optical Tracking?• Optical tracking is a means of determining in real-time the

position of an object by tracking the positions of eitheractive or passive infrared markers attached to the object.The position of the point of reflection is determined using acamera system.

Active markers Passive markers Camera

Meeks RSNA 2002

Page 6: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Stereo Correspondence

Page 7: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

How Does it Work? Optical Tracking

Meeks RSNA 2002

Page 8: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Calibration to Isocenter

Meeks RSNA 2002

Page 9: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

pi’ = Rp

i +T

Vector forroomcoordinates

3x3 rotation matrix

Translation vector

Equation can be solved numerically usingoptimization algorithms (Hook and Jeeves,etc.), or closed form solutions such assingle value decomposition or Horn’smethod (quaternions)

Vector forimagecoordinates

Meeks RSNA 2002

Page 10: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Infrared Camera Alignments

Meeks, S.L., et al., Image localization for framelessstereotactic radiotherapy. Int J Radiat Oncol Biol Phys, 2000.46(5): p. 1291-9.

Tome, W.A., et al., Optically guided intensity modulatedradiotherapy. Radiother Oncol, 2001. 61(1): p. 33-44.

Page 11: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Other Alignment Systems (VisionRT)

Page 12: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Waldron, T. Univ of Iowa

Page 13: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

C-Rad Sentinel™

LAP: Galaxy

Page 14: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Waldron, T. Univ of Iowa

Page 15: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Waldron, T. Univ of Iowa

Page 16: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Video and Laser ReferencesMoore, C., et al., Opto-electronic sensing of body surface topologychanges during radiotherapy for rectal cancer. Int J Radiat Oncol BiolPhys, 2003. 56(1): p. 248-58.

Schoffel, P.J., et al., Accuracy of a commercial optical 3D surfaceimaging system for realignment of patients for radiotherapy of thethorax. Phys Med Biol, 2007. 52(13): p. 3949-63.

Bert, C., et al., A phantom evaluation of a stereo-vision surfaceimaging system for radiotherapy patient setup. Med Phys, 2005. 32(9):p. 2753-62.

Siebert, Human Body 3D imaging by speckle texture projectionphotogrammetry. Sensor Review, 2000. 20(3).

Page 17: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Super Dimension: RF guidedBronchoscopy

Transpondertip

Page 18: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Ascension Technology products use RF sensors to track the position and orientation in real-timeof instruments including ultrasound probes. Tracking accuracy is unaffected by the nearby presenceof conductive metals including aluminum, titanium and stainless steel 300

Ascension Technology

Page 19: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

CalypsoMedicalSystemExcitationWaveform

SourceCoil

Current

ResponseWaveform

Resonator

Current

ExcitationPhase

RingDownPhase

Page 20: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

RF ReferencesWagner, A., et al., Quantitative analysis of factors affecting intraoperative precision andstability of optoelectronic and electromagnetic tracking systems. Med Phys, 2002. 29(5):p. 905-12.

Hummel, J.B., et al., Design and application of an assessment protocol forelectromagnetic tracking systems. Med Phys, 2005. 32(7): p. 2371-9.

Meskers, C.G., et al., Calibration of the "Flock of Birds" electromagnetic tracking deviceand its application in shoulder motion studies. J Biomech, 1999. 32(6): p. 629-33.

Santanam, L., et al., Fiducial-based translational localization accuracy of electromagnetictracking system and on-board kilovoltage imaging system. Int J Radiat Oncol Biol Phys,2008. 70(3): p. 892-9.

Willoughby, T.R., et al., Target localization and real-time tracking using the Calypso 4Dlocalization system in patients with localized prostate cancer. Int J Radiat Oncol BiolPhys, 2006. 65(2): p. 528-34.

Page 21: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Evaluation of Collision Space

Calypso System during Commissioning

Page 22: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Calibration to Isocenter

Page 23: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

End to End test

1 Scan of Phantom2 Treatment Plan of Phantom3 Localization of Phantom4 Orthogonal Films of Central Target5 Analysis

Page 24: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Localization onTreatment PlanningSystem: IR Example1

Tome RSNA 2002

Page 25: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Setup of at Treatment Machine usingOptical Guidance: Example 1

Tome RSNA 2002

Page 26: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Resulting Film: Measure of TotalAccuracy of System

Overall error = 0.789mm

Predicted error:

Z-Pixel Size = 1.25mm

X-Pixel Size = 0.703 mm

Y-Pixel Size = 0.703 mm

Predicted Error = 1.59mm

Results:

Z: 0.49 mm to T

X: 0.35 mm to A

Y: 0.50 mm High

Tome RSNA 2002

Page 27: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Example 2: Phantom for Calypso system(Treatment plan of Implanted target)

Page 28: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Example 2: Phantom for Calypso system

Page 29: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Meeks AAPM 2000

Page 30: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Meeks, AAPM 2000

Page 31: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Test of Localization: Introduce offsets andmeasure localization system offset

Page 32: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Phantom

Beacon® Phantom

ValidationDigitizer

3X 1DStages

Page 33: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Tracking AccuracyMeasurements

Page 34: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

Phantom at isocenterLocalizationaccuracy

PassCollision interlocksSafety

AccuracyMethodTest

Installation

Daily QA

Tracking Rage

Range of Tracking

Range of Localization

AccuracyMethodTest

Per manufacturerspecification

Move table while tracking tomaximum range

Move table while localizing tomaximum range

Localization system interferencewith radiation delivery system

Linac interference withlocalization system

Collision spaceSafety

Page 35: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

AccuracyMethodTest

Shift phantom from isocenterAccuracy in tracking upto 10cm fromisocenter

Data transmittedcorrectly

Test patient transferred fromplanning system tolocalization system

Data transfer

Motion tableTracking accuracy overclinical range: atclinical rate ofmotion

System end-to-end test (with CTscan, treatment plan andorthogonal portal films)

Localization accuracyMachine spec.Following Linac QA TG reportsIsocenter QA

Following Linac QA TG reportsLaser localizationsystem QA

Machine interface: Gatingtermination, table auto-translation,

Safety

Monthly (in addition to Daily): Proposed

Page 36: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

AccuracyMethodTest

Accurate motion tableSystem latency andtracking timing

Repeat system alignment atleast 10 times to localizea fixed phantom

Reproducibility

Alignment vs. timeDrift in measuredisocenter over timeof use

PassSystem mounting brackets(all cameras are secure)

PassEmergency off buttons arefunctional

PassElectrical System:Test/reset buttons &breakers are functional

Safety

Annually (in addition to Monthly)

Page 37: Update on TG 147: QA for non- radiographic localization ... · radiographic localization and positioning systems AAPM Anaheim, CA 2009 Twyla Willoughby. Thank-You ... Example 1 Tome

ReferencesGierga, D.P., et al., Comparison of target registration errors formultiple image-guided techniques in accelerated partial breastirradiation. Int J Radiat Oncol Biol Phys, 2008. 70(4): p. 1239-46.

Serban, M., et al., A deformable phantom for 4D radiotherapyverification: design and image registration evaluation. MedPhys, 2008. 35(3): p. 1094-102

Kutcher, G.J., et al., Comprehensive QA for radiation oncology:report of AAPM Radiation Therapy Committee Task Group 40.Med Phys, 1994. 21(4): p. 581-618