Upload File

us food and drug administration: 2005-4089t2

413
 1  NEAL R. GROSS COURT REPORTERS AND TRANSCRIBERS 1323 RHODE ISLAND AVE., N.W. (202) 234-4433 WASHINGTON, D.C. 20005-3701 www.nealrgross.com nyUNITED STATES OF AMERICA FOOD AND DRUG ADMINISTRATION OFFICE OF THE COMMISSIONER PEDIATRICS ADVISORY COMMITTEE SIXTH MEETING TUESDAY, FEBRUARY 15, 2005 The Advisory Committee met at 8:00 a.m. in Room 1066 of the Food and Drug Administration, 5630 Fishers Lane, Rockville, Maryland, Dr. Joan Chesney, Chair, presiding. PRESENT: P. JOAN CHESNEY, M.D., Chair ELIZABETH B. ANDREWS, M.P.H., Ph.D.,Voting Consultant DENNIS M. BIER, M.D., Member RUTH S. DAY, Ph.D., Voting Consultant  ANGELA DIAZ, M.D., M.P.H., Member DEBORAH L. DOKKEN, MPA, Patient-Family Representative ROSELYN E. EPPS, M.D., Voting Consultant MICHAEL E. FANT, M.D., Ph.D., Member NORMAN FOST, M.D., M.P.H., Voting Consultant ELIZABETH A GAROFALO, M.D., Industry Representative MARY GLODE, M.D., Member RICHARD L. GORMAN, M.D., Pediatric Health Organization Representative PAULA KNUDSON, Consultant-Consumer Representative DONALD R. MATTISON, M.D., Voting Consultant JOHN WILLIAM MURRAY MOORE, M.D., M.P.H., Member THOMAS B. NEWMAN, M.D., M.P.H., Member JUDITH R. O'FALLON, Ph.D., Member VICTOR M. SANTANA, M.D., Member ROBERT STERN, M.D., Voting Consultant JAN N. JOHANNESSEN, Ph.D., Executive Secretary

Upload: fda

Post on 31-May-2018

218 views

Category:

Documents


0 download

Report

TRANSCRIPT

Page 1: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 1/412

Page 2: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 2/412

Page 3: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 3/412

Page 4: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 4/412

Page 5: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 5/412

Page 6: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 6/412

Page 7: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 7/412

Page 8: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 8/412

Page 9: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 9/412

Page 10: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 10/412

Page 11: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 11/412

Page 12: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 12/412

Page 13: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 13/412

Page 14: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 14/412

Page 15: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 15/412

Page 16: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 16/412

Page 17: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 17/412

Page 18: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 18/412

Page 19: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 19/412

Page 20: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 20/412

Page 21: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 21/412

Page 22: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 22/412

Page 23: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 23/412

Page 24: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 24/412

Page 25: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 25/412

Page 26: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 26/412

Page 27: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 27/412

Page 28: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 28/412

Page 29: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 29/412

Page 30: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 30/412

Page 31: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 31/412

Page 32: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 32/412

Page 33: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 33/412

Page 34: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 34/412

Page 35: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 35/412

Page 36: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 36/412

Page 37: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 37/412

Page 38: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 38/412

Page 39: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 39/412

Page 40: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 40/412

Page 41: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 41/412

Page 42: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 42/412

Page 43: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 43/412

Page 44: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 44/412

Page 45: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 45/412

Page 46: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 46/412

Page 47: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 47/412

Page 48: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 48/412

Page 49: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 49/412

Page 50: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 50/412

Page 51: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 51/412

Page 52: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 52/412

Page 53: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 53/412

Page 54: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 54/412

Page 55: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 55/412

Page 56: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 56/412

Page 57: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 57/412

Page 58: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 58/412

Page 59: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 59/412

Page 60: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 60/412

Page 61: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 61/412

Page 62: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 62/412

Page 63: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 63/412

Page 64: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 64/412

Page 65: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 65/412

Page 66: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 66/412

Page 67: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 67/412

Page 68: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 68/412

Page 69: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 69/412

Page 70: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 70/412

Page 71: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 71/412

Page 72: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 72/412

Page 73: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 73/412

Page 74: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 74/412

Page 75: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 75/412

Page 76: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 76/412

Page 77: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 77/412

Page 78: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 78/412

Page 79: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 79/412

Page 80: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 80/412

Page 81: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 81/412

Page 82: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 82/412

Page 83: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 83/412

Page 84: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 84/412

Page 85: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 85/412

Page 86: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 86/412

Page 87: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 87/412

Page 88: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 88/412

Page 89: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 89/412

Page 90: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 90/412

Page 91: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 91/412

Page 92: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 92/412

Page 93: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 93/412

Page 94: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 94/412

Page 95: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 95/412

Page 96: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 96/412

Page 97: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 97/412

Page 98: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 98/412

Page 99: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 99/412

Page 100: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 100/412

Page 101: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 101/412

Page 102: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 102/412

Page 103: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 103/412

Page 104: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 104/412

Page 105: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 105/412

Page 106: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 106/412

Page 107: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 107/412

Page 108: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 108/412

Page 109: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 109/412

Page 110: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 110/412

Page 111: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 111/412

Page 112: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 112/412

Page 113: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 113/412

Page 114: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 114/412

Page 115: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 115/412

Page 116: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 116/412

Page 117: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 117/412

Page 118: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 118/412

Page 119: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 119/412

Page 120: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 120/412

Page 121: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 121/412

Page 122: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 122/412

Page 123: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 123/412

Page 124: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 124/412

Page 125: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 125/412

Page 126: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 126/412

Page 127: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 127/412

Page 128: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 128/412

Page 129: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 129/412

Page 130: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 130/412

Page 131: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 131/412

Page 132: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 132/412

Page 133: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 133/412

Page 134: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 134/412

Page 135: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 135/412

Page 136: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 136/412

Page 137: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 137/412

Page 138: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 138/412

Page 139: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 139/412

Page 140: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 140/412

Page 141: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 141/412

Page 142: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 142/412

Page 143: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 143/412

Page 144: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 144/412

Page 145: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 145/412

Page 146: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 146/412

Page 147: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 147/412

Page 148: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 148/412

Page 149: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 149/412

Page 150: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 150/412

Page 151: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 151/412

Page 152: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 152/412

Page 153: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 153/412

Page 154: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 154/412

Page 155: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 155/412

Page 156: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 156/412

Page 157: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 157/412

Page 158: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 158/412

Page 159: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 159/412

Page 160: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 160/412

Page 161: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 161/412

Page 162: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 162/412

Page 163: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 163/412

Page 164: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 164/412

Page 165: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 165/412

Page 166: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 166/412

Page 167: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 167/412

Page 168: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 168/412

Page 169: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 169/412

Page 170: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 170/412

Page 171: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 171/412

Page 172: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 172/412

Page 173: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 173/412

Page 174: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 174/412

Page 175: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 175/412

Page 176: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 176/412

Page 177: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 177/412

Page 178: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 178/412

Page 179: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 179/412

Page 180: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 180/412

Page 181: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 181/412

Page 182: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 182/412

Page 183: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 183/412

Page 184: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 184/412

Page 185: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 185/412

Page 186: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 186/412

Page 187: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 187/412

Page 188: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 188/412

Page 189: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 189/412

Page 190: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 190/412

Page 191: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 191/412

Page 192: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 192/412

Page 193: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 193/412

Page 194: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 194/412

Page 195: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 195/412

Page 196: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 196/412

Page 197: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 197/412

Page 198: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 198/412

Page 199: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 199/412

Page 200: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 200/412

Page 201: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 201/412

Page 202: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 202/412

Page 203: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 203/412

Page 204: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 204/412

Page 205: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 205/412

Page 206: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 206/412

Page 207: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 207/412

Page 208: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 208/412

Page 209: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 209/412

Page 210: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 210/412

Page 211: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 211/412

Page 212: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 212/412

Page 213: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 213/412

Page 214: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 214/412

Page 215: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 215/412

Page 216: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 216/412

Page 217: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 217/412

Page 218: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 218/412

Page 219: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 219/412

Page 220: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 220/412

Page 221: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 221/412

Page 222: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 222/412

Page 223: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 223/412

Page 224: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 224/412

Page 225: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 225/412

Page 226: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 226/412

Page 227: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 227/412

Page 228: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 228/412

Page 229: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 229/412

Page 230: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 230/412

Page 231: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 231/412

Page 232: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 232/412

Page 233: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 233/412

Page 234: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 234/412

Page 235: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 235/412

Page 236: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 236/412

Page 237: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 237/412

Page 238: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 238/412

Page 239: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 239/412

Page 240: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 240/412

Page 241: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 241/412

Page 242: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 242/412

Page 243: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 243/412

Page 244: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 244/412

Page 245: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 245/412

Page 246: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 246/412

Page 247: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 247/412

Page 248: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 248/412

Page 249: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 249/412

Page 250: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 250/412

Page 251: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 251/412

Page 252: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 252/412

Page 253: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 253/412

Page 254: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 254/412

Page 255: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 255/412

Page 256: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 256/412

Page 257: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 257/412

Page 258: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 258/412

Page 259: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 259/412

Page 260: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 260/412

Page 261: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 261/412

Page 262: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 262/412

Page 263: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 263/412

Page 264: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 264/412

Page 265: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 265/412

Page 266: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 266/412

Page 267: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 267/412

Page 268: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 268/412

Page 269: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 269/412

Page 270: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 270/412

Page 271: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 271/412

Page 272: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 272/412

Page 273: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 273/412

Page 274: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 274/412

Page 275: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 275/412

Page 276: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 276/412

Page 277: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 277/412

Page 278: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 278/412

Page 279: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 279/412

Page 280: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 280/412

Page 281: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 281/412

Page 282: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 282/412

Page 283: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 283/412

Page 284: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 284/412

Page 285: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 285/412

Page 286: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 286/412

Page 287: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 287/412

Page 288: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 288/412

Page 289: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 289/412

Page 290: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 290/412

Page 291: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 291/412

Page 292: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 292/412

Page 293: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 293/412

Page 294: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 294/412

Page 295: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 295/412

Page 296: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 296/412

Page 297: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 297/412

Page 298: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 298/412

Page 299: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 299/412

Page 300: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 300/412

Page 301: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 301/412

Page 302: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 302/412

Page 303: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 303/412

Page 304: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 304/412

Page 305: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 305/412

Page 306: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 306/412

Page 307: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 307/412

Page 308: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 308/412

Page 309: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 309/412

Page 310: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 310/412

Page 311: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 311/412

Page 312: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 312/412

Page 313: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 313/412

Page 314: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 314/412

Page 315: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 315/412

Page 316: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 316/412

Page 317: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 317/412

Page 318: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 318/412

Page 319: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 319/412

Page 320: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 320/412

Page 321: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 321/412

Page 322: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 322/412

Page 323: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 323/412

Page 324: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 324/412

Page 325: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 325/412

Page 326: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 326/412

Page 327: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 327/412

Page 328: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 328/412

Page 329: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 329/412

Page 330: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 330/412

Page 331: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 331/412

Page 332: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 332/412

Page 333: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 333/412

Page 334: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 334/412

Page 335: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 335/412

Page 336: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 336/412

Page 337: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 337/412

Page 338: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 338/412

Page 339: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 339/412

Page 340: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 340/412

Page 341: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 341/412

Page 342: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 342/412

Page 343: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 343/412

Page 344: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 344/412

Page 345: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 345/412

Page 346: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 346/412

Page 347: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 347/412

Page 348: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 348/412

Page 349: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 349/412

Page 350: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 350/412

Page 351: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 351/412

Page 352: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 352/412

Page 353: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 353/412

Page 354: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 354/412

Page 355: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 355/412

Page 356: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 356/412

Page 357: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 357/412

Page 358: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 358/412

Page 359: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 359/412

Page 360: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 360/412

Page 361: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 361/412

Page 362: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 362/412

Page 363: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 363/412

Page 364: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 364/412

Page 365: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 365/412

Page 366: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 366/412

Page 367: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 367/412

Page 368: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 368/412

Page 369: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 369/412

Page 370: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 370/412

Page 371: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 371/412

Page 372: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 372/412

Page 373: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 373/412

Page 374: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 374/412

Page 375: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 375/412

Page 376: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 376/412

Page 377: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 377/412

Page 378: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 378/412

Page 379: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 379/412

Page 380: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 380/412

Page 381: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 381/412

Page 382: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 382/412

Page 383: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 383/412

Page 384: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 384/412

Page 385: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 385/412

Page 386: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 386/412

Page 387: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 387/412

Page 388: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 388/412

Page 389: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 389/412

Page 390: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 390/412

Page 391: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 391/412

Page 392: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 392/412

Page 393: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 393/412

Page 394: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 394/412

Page 395: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 395/412

Page 396: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 396/412

Page 397: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 397/412

Page 398: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 398/412

Page 399: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 399/412

Page 400: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 400/412

Page 401: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 401/412

Page 402: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 402/412

Page 403: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 403/412

Page 404: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 404/412

Page 405: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 405/412

Page 406: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 406/412

Page 407: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 407/412

Page 408: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 408/412

Page 409: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 409/412

Page 410: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 410/412

Page 411: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 411/412

Page 412: US Food and Drug Administration: 2005-4089T2

8/14/2019 US Food and Drug Administration: 2005-4089T2

http://slidepdf.com/reader/full/us-food-and-drug-administration-2005-4089t2 412/412


US Food and Drug Administration: 2005-4165S1 06

3 Drug Administration

Jordan Food & Drug Administration

Drug Administration 2011

US Food and Drug Administration: 2005-4180s 02 iyasu

Pediatric Drug AdministrationPediatric Drug Administration

pediatric Drug administration

Food and Drug Administration

FOOD AND DRUG ADMINISTRATION Food and Drug Administration

DEA (Drug Enforcement Administration)

Drug Enforcement Administration (DEA) Writing Style … · Description of document: Drug Enforcement Administration (DEA) Writing Style Guide, 2005 . Request date: 20-June-2014

Routes of Drug Administration OBJECTIVES: 1. Know the different Routes of Drug Administration 2. Differentiate between Enteral and Parenteral Drug Administration

Alternative Routes of Drug Administration (analgesia)...Alternative Routes of Drug Administration (analgesia) Dr Andrew Dickman. Consultant Pharmacist. Alternative Routes of Drug Administration

PHARMACODYNAMIC ASPECTS OF MODES OF DRUG ADMINISTRATION FOR OPTIMIZATION OF DRUG …. 1999... · 2005-07-31 · drug dose on magnitude of pharmacologic effect is presented in Figure

FOOD AND DRUG ADMINISTRATION COMPLIANCE … · food and drug administration compliance program guidance manual ... food and drug administration compliance program guidance ... nitrous

Drug Enforcement Administration

US Food and Drug Administration: 2005-4137S2 02 Hussain

© 2005 EU Hygiene Regulations Food & Drug Administration Bangkok, Thailand 3 rd April 2007 Dorothy Guina-Dornan

2 Drug Administration

2005/2006 SWGDRUG ACCOMPLISHMENTS Drug Enforcement Administration Office of Forensic Sciences sponsored by the Office of National Drug Control Policy and

1 Drug abuse and drug dependence Zhou Yanqiong 2 Broad definition of drug abuse: Unreasonable administration Unreasonable administration （ drug abuse

OCT 13 2005 - Food and Drug Administration

Drug Administration

CDER Drug Safety Oversight Board Douglas C. Throckmorton, M.D. Deputy Director, CDER Food and Drug Administration November 5, 2005

Drug Formulations & Routes of Administrationmedicinaingles.weebly.com/.../3908857/drug...routes_of_administrati… · •routes of administration ... Routes of Drug Administration

Routes of Drug administration

Intravenous Drug Administration

Routes of drug administration

Food and Drug Administration Division of Pulmonary and Allergy Drug Products Pulmonary-Allergy Drugs Advisory Committee Meeting July 13, 2005 Safety of

Route of Drug Administration

484_route of Drug Administration