uthsc dental research handbook

DENTAL RESEARCH Handbook

UNIVERSITY OF TENNESSEE College of Dentistry

THE UNIVERSITY of TENNESSEE

HEALTH SCIENCE CENTER

COLLEGE of DENTISTRY

PREFACE 4 • Timothy L. Hottel, D.D.S., M.S., M.B.A.

Dean, College of Dentistry INTRODUCTION 5

• Franklin Garcia-Godoy, D.D.S., M.S. Senior Executive Associate Dean for Research

DEPARMENT CONTACTS 6 CENTERS FOR DENTAL RESEARCH 7 DENTAL RESEARCH AT UTHSC 8

• Biomaterials Research 8 • Craniofacial Research 9

SECTION I: FACULTY IN RESEARCH 11

A) Department of Bioscience Research 12 o Bioscience Research Staff 23

B) Funded Research Faculty 24 o Federal, Industrial, or Foundational Grants 25 o Dental Alumni Research Grants 29

SECTION II: STUDENTS IN RESEARCH 37

• For Students Interested in Research 39 • Student Research Training Program 41

- Details of the Program 42 - Selecting a Research Mentor 43 - 2010 Student Summer Research Mentors 44 - Steps to Follow 48

• Student Research Day 49 • Hinman Student Research Symposium 50

TABLE OF Contents

Increased emphasis has been placed on research in the College of Dentistry. Although our primary mission is to train successful general dentists, dental research is an important part of the educational process.

With the successful hiring of several research-oriented faculty, the University of Tennessee College of Dentistry has appeared in publications ranging from the Dental Products Reports to texts like “Cancer Metastasis – Biology and Treatment.” We are poised to become a leader in dental research with new industry support and multiple new research grants, covering areas from sealants to stem cells.

For this, I would like to thank those who have supported faculty and student research efforts to advance the dental profession – with a special thanks to our alumni.

Timothy L. Hottel, D.D.S., M.S., M.B.A.

Dean, College of Dentistry

PREFACE Dean Hottel

The purpose of this compendium of current research efforts in the College of Dentistry at the University of Tennessee Health Science Center is to facilitate communication and collaboration in research among faculty; to assist students in selecting areas of research and mentors for their student research projects; and, to inform the alumni and other health professionals in the Mid-South and the dental industry of the expertise and assistance that is available to prospective researchers in the UT College of Dentistry.

Franklin Garcia-Godoy, D.D.S., M.S.

Senior Executive Associate Dean for Research Chair, Department of Bioscience Research

Director, Bioscience Research Center Professor, Department of Physiology

INTRODUCTION Senior Executive Associate Dean for Research

ADMINISTRATION DEAN

Timothy L.Hottel, D.D.S., M.S., M.B.A. (901) 448-6200 ASSOCIATE DEANS Academic and Institutional Affairs Mark R. Patters, D.D.S., Ph.D. (901) 448-7886

Admissions & Student Affairs (Interim Associate Dean)

John S. Covington, III, D.D.S., M.S., F.R.S.M. (901) 448-6268 Clinical Affairs Lloyd A. George, D.D.S., M.Ed., J.D. (901) 448-6413 Research Franklin Garcia-Godoy, D.D.S., M.S. (901) 448-6333

DEPARTMENT CHAIRS BIOLOGIC & DIAGNOSTIC SCIENCES John S. Covington, D.D.S. M.S. F.R.S.M. (901) 448-8609 BIOSCIENCE RESEARCH Franklin Garcia-Godoy, D.D.S., M.S. (901) 448-6333 ENDODONTICS Peter DiFiore, D.D.S., M.S. (Interim Chair) (901) 448-6618 ORAL & MAXILLOFACIAL SURGERY Lawrence W. Weeda, Jr., D.D.S. (901) 448-6236 ORTHODONTICS Terry M. Trojan, D.D.S., M.S. (Interim Chair) (901) 448-6214 PEDIATRIC DENTISTRY & COMMUNITY ORAL HEALTH Bill W McCann, D.D.S., M.S. (Interim Chair) (901) 448-6206 PERIODONTOLOGY Paul S. Bland, D.D.S. (901) 448-6242 PROSTHODONTICS Russell A. Wicks, D.D.S. (901) 448-6380 RESTORATIVE Janet Harrison, D.D.S. (901) 448-6692

DEPARTMENT Contacts

Dental research is being conducted at a variety of laboratories and clinics across the University of Tennessee Health Science Center campus, as well as at regional medical and public health centers in Tennessee and Arkansas. However, the designated campus dental research centers are listed below.

BIOMATERIALS RESEARCH CENTER 138 Nash Research Building 894 Union Avenue

BIOSCIENCE RESEARCH CENTER

N102 Dunn Dental Building 875 Union Avenue

CANCER RESEARCH CENTER

119 Cancer Research Building 19 S. Manassas Street

CLINICAL RESEARCH CENTER

Dunn Dental Building, 3rd Floor 875 Union Avenue

CRANIOFACIAL RESEARCH CENTER

429/B12 Boling Center 711 Jefferson Avenue

TMD/SLEEP DISORDER CLINIC Dunn Dental Building, 3rd Floor 875 Union Avenue

CENTERS FOR Dental Research

Listed below is a summary of the different types of research currently being conducted by faculty in the COLLEGE of DENTISTRY at THE UNIVERSITY of TENNESSEE HEALTH SCIENCE CENTER. This list is not exhaustive. BIOMATERIALS RESEARCH Biomaterials Development

• Microtensile fracture strength testing • Profilometer fracture mode testing • Fatigue, thermocycling and load testing • Scanning electron microscope evaluation • Confocal electron microscope evaluation • Leakage testing • Hybrid layer evaluation • Remineralization and demineralization studies • Color and gloss analysis • Implant coatings

Clinical Testing

• Whitening kits • Restorative materials • Endodontic materials • Periodontal therapies • Prosthodontic devices • Toothpaste • Mouthwash • Adhesives • Disinfectants • Analgesics • Drugs • Lasers • Dental instruments and devices • Toothbrushes (manual or power) • Ortho appliances/devices • Dental floss • Implants • Plaque and gingivitis

DENTAL RESEARCH at UTHSC

Toothbrushing

• Dentifrice testing • Abrasion testing • Wear testing • Clinical testing • Biofilm

Biocompatibility Testing

• Drugs and biomaterials • In vitro cytotoxicity • In vivo biocompatibility • Histological assessment • Genotoxicity assessment

Molecular Assays

• Protein/Gene activation • PCR • Gene silencing • Gene isolation • Molecular pathway elucidation • Stem cells

CRANIOFACIAL RESEARCH Inflammation Research

• Tissue alterations in periodontal diseases • Cellular response to anti-inflammatory drugs (i.e., COX inhibitors, transcription

factor inhibitors), natural products (i.e., myrrh oil, tea tree oil, cranberry components), and oral rinses

• Levels of arachidonic acid metabolites in gingival crevicular fluid in gingivitis/periodontitis

• Role of fibroblast production of matrix metalloproteinases and inflammatory mediators in periodontal diseases and inflammatory TMJ destruction

• Effects of methamphetamine on gingival fibroblasts and neutrophils in periodontitis

Innate Immunity • Role of peroxidase enzymes of leukocytes and saliva in producing antimicrobial

oxidizing agents that protect tissues against microbial infection and inflammation • Antibiotic peptides produced by human leukocytes, oral epithelial cells, and the

salivary glands. Mechanisms of antimicrobial activity and the molecular basis for microbial resistance

Oral Cancer

• Analysis of tumor cell invasion and metastatic potential • Testing therapeutic potential of anti-tumor agents • Immunolocalization of specific tumor antigens in cells and tissue

Proteomic Analysis and Protein Expression Patterns

• Proteomic analysis of cells and tissues • Tumor marker identification, characterization, and prognostic value

Bone Metabolism

• Effects of drugs (i.e., bisphosphonates and statins) and natural products (i.e., cranberry components) on soft tissue cell (gingival fibroblast and epithelial cell) production of mediators of bone metabolism (i.e., IL-6, RANKL, OPG)

Gingival Fibroses • Gingival fibroblast production/regulation of extracellular matrix molecules and

matrix metalloproteinases in gingival fibroses (hereditary/idiopathic, drug-induced)

Molecular Assays • PCR • Bacterial gene isolation and gene product identification • Protein expression from isolated gene • DNA analysis

Clinical Testing

• Assay for efficacy of mouthwash and toothpaste, using in vitro analysis • Evaluation of periodontal therapy products • Effects of natural products such as cannabidiol • Testing for biofilm in dental waterline (screening and enumeration of microbial

populations in dental waterlines; culturing anaerobic bacteria)

Biomaterials Testing • Cellular and tissue response to implant materials and other biomaterials • Cytotoxicity of implant and other biomaterials • Genotoxicity testing • Biofilm formation

Craniofacial Pain

• Therapy and treatment of neck and facial pain that is associated with temporomandibular joint disorders (TMD)

• Treatment of sleep apnea and other sleep disordered breathing conditions through development and use of oral appliances

SECTION I: Faculty in Research

The Department of Bioscience Research houses the College of Dentistry’s Research Faculty, or faculty whose majority effort is dedicated to conducting dental research.

PART A: Department of Bioscience Research

Associate Professor, Department of Bioscience Research Education:

Ph.D., 1981, Michigan State University M.S., 1974, West Virginia University M.Sc., 1971, Osmania University, India

Office Phone: (901) 448-4342 Email: [email protected] Research Interests:

• Bacterial pathogenesis • Biofilm • Genomics of oral pathogens • Monocyte interactions with LPS of periodontal pathogens

Research Funding:

• Private Industry • University of Tennessee College of Dentistry Alumni Endowment Fund

Selected Publications:

• Babu JP, Ofek I. Cranberry high molecular weight constituent affect selectively metabolic activity of Streptococcus sanguis in biofilm. Microbios. 2010 (accepted for publication).

• Babu JP, Saha BK. Identification and characterization of Fusobacterium nucleatum surface components that mediate its interaction with salivary molecules. FEMS Microb Lett. 1997;117:32-38.

• Babu JP, Dean JW, Pabst MJ. Attachment of Fusobacterium nucleatum to fibronectin immobilized on a solid phase. J Periodontal. 1995;666:285-290.

• Babu JP, Dabbous MKh, Abraham SN. Isolation and characterization of a 180-kiloDalton salivary glycoprotein which mediates the attachment of Actinomyces naeslundii to human buccal epithelial cells. J Periodontal Res. 1991 Mar;26(2):97-106

• Babu JP, Abraham SN, Dabbous MKh, Beachey EH. Interaction of a 60-kiloDalton D-mannose-containing salivary glycoprotein with type 1 fimbriae of Escherichia coli. Infect Immun. 1986 Oct;54(1):104-108.

• Babu JP, Beachey EH, Hasty DL, Simpson WA. Isolation and characterization of a 60-kilodalton salivary glycoprotein with agglutinating activity against strains of Streptococcus mutans. Infect Immun. 1986 Aug;51:405-413.

• Babu JP, Simpson WA, Courtney HS, Beachey EH. Interaction of human plasma fibronectin with cariogenic and non-cariogenic oral streptococci. Infect Immun. 1983;41:162-167.

JEGDISH P. BABU, M.SC., M.S., PH.D.

mailto:[email protected]�

Assistant Professor, Department of Bioscience Research Director, TMD/Sleep Disorder Clinic Diplomate, Academy of Clinical Sleep Disorders Dentistry Fellow, Academy of Craniofacial Pain Education:

D.D.S., 1992, University of Tennessee College of Dentistry B.S., 1982, University of Arkansas Office Phone: (901)448-1285 Email: [email protected] Research Interests:

• Craniofacial pain • Temporomandibular joint dysfunction (TMD) therapy and treatment • Sleep disorders (sleep disordered breathing and obstructive sleep apnea) and their

relationships to craniofacial pain

Research Funding: • None at present


N/A

MELODY BARRON, D.D.S.


Adjunct Professor, Department of Bioscience Research Associate Professor, Joint Biomedical Engineering Program (UTHSC and University of Memphis) Education: Fullbright Fellowship, 1993-1994, Umeå University, Umeå, Sweden

Ph.D., 1988, University of Alabama at Birmingham M.S., 1988, University of Alabama at Birmingham B.S., 1988, University of Alabama at Birmingham B.S., 1984, Florida State University Office Phone: (901) 678-5243 Email: [email protected] / [email protected] Research Interests:

• Bone tissue engineering/Guided bone regeneration • Biomaterials development; corrosion/degradation of biomaterials. • Drug delivery • Dental implants and restorative alloys • Cell biomechanics

Research Funding:

• National Institutes of Health • National Science Foundation • Private Industry and Research Foundations


• Chesnutt BM, Viano AM, Yuan Y, Yang Y, Guda T, Appleford MR, Ong JL, Haggard WO, Bumgardner JD. Design and characterization of a noval chitosan/nanocrystalline calcium phosphate composite scaffold for bone regeneration. J Biomed Mat Res. 2009;88A(2):491-502

• Norowski PA, Bumgardner JD. Biomaterial and antibiotic strategies for perio-implantitis: A review. J Biomed Mat Res. 2009;88B(2):530-543

• Bumgardner JD, Chesnutt BM, Yuan Y, Yang Y, Appleford M, Oh S, McLaughlin R, Elder S, Ong JL. The integration of chitosan-coated titanium in bone: An in vivo study in rabbits. Implant Dent. 2007;16(1):66-79

• Martin HJ, Schultz KH, Bumgardner JD, Walters KB. XPS study on the use of 3-Aminopropyltriethoxysilane to bond chitosan to a titanium surface. Lanmuir. 2007;23(12):6645-6651

• Lin HY, Bumgardner JD. Changes in the surface oxide composition of Co-Cr-Mo implant alloy by macrophage cells and their released reactive chemical species. Biomat. 2004;25(7-8):1233-1238

• Bumgardner JD, Wiser R, Gerard PD, Bergin P, Chestnutt B, Marini M, Ramsey V, Elder SH, Gilbert JA. Chitosan: Potential use as a bioactive coating for orthopaedic and craniofacial/dental implants. J Biomat Sci. 2003;14(5):423-4238

• Roach MD, Wolan JT, Parsell DE, Bumgardner JD. Use of x-ray photoelectron spectroscopy and cyclic polarization to evaluate the corrosion behavior of six nickel-chromium alloys before and after porcelain-fused-to-metal firing. J Prosth Dent. 2000;84(6):623-634

JOEL D. BUMGARDNER, PH.D.



MUSTAFA KH.DABBOUS, PH.D. Professor, Department of Bioscience Research Professor, Department of Microbiology and Immunology, College of Medicine Professor (Hon.), College of Medicine, University of Tanta, Egypt Education: Ph.D., 1967, University of Tennessee Medical Units, Memphis, TN M.Sc., 1965, Massachusetts Institute of Technology (MIT) Office Phone: (901) 448-6167 Email: [email protected] Research Interests:

• Connective tissue alterations in periodontal disease (the matrix collagens and matrix metalloproteinases)

• Tumor invasion and metastasis; the role of matrix metalloproteinases in metastatic spread • Tumor-specific cytokines in cell motility and their correlation with metastatic potential • Tumor markers and metastatic potential of tumor cells

Research Funding:

• National Institutes of Health • Private Industry • Private Foundations


• Dabbous MKh, Jefferson MM, Haney J, Thomas EL. Biomarkers of metastatic potential in cultured adenocarcinoma clones. Clin Exper Metastasis. Accepted (2010).

• Tipton DA, Seshul B, Dabbous MKh. Effect of bisphosphonates on human gingival fibroblast production of mediators of osteoclastogenesis: RANKL, OPG, and IL-6. Periodontal Res. Accepted (2010).

• Tipton DA, Legan ZT, Dabbous MKh. Methamphetamine cytotoxicity and effect on LPS-stimulated IL-1beta production by human monocytes. Toxicol In Vitro. 2010 Apr; 24(3):921-7.

• Adlam DJ, Dabbous MKh, Woolley DE. Electrochemical monitoring of rat mammary adenoarcinoma cells: An in vitro assay for anticancer drug selection. Assay Drug Dev Technol. 2008;6:795-802.

• Tipton DA, Hamman NR, Dabbous MKh. Effect of myrrh oil on IL-1beta stimulation of NG-kappaB activation and PEG(2) production in human gingival fibroblasts and epithelial cells. Toxicol In Vitro. 2006 Mar; 20(2):248-55.

• Tipton DA, Woodard ES 3rd, Baber MA, Dabbous MKh. Role of c-myc proto-oncogene in the proliferation of hereditary gingival fibromatosis fibroblasts. J Periodontol. 2004 Mar; 75(3):360-9.

• Tipton DA, Flynn JC, Stein SH, Dabbous MKh. Cycloozygenase-2 inhibitors decrease interleukin-1beta-stimulated prostaglandin E2 and IL-6 production by human gingival fibroblasts. J Periodontol. 2003 Dec; 74(12):1754-63.

• Tipton DA, Lyle B, Babich H, Dabbous MKh. In vitro cytotoxic and anti-inflammatory effects of myrrh oil on human gingival fibroblasts and epithelial cells. Toxicol In Vitro. 2003 Jun; 17(3):301-10.


FRANKLIN GARCIA-GODOY, D.D.S., M.S. Senior Executive Associate Dean of Research Chair, Department of Bioscience Research Director, Bioscience Research Center Professor, Department of Physiology, UTHSC Adjunct Professor, Department of Biomedical Engineering, University of Memphis Adjunct Professor, Department of Biomedical Engineering, Florida International University Senior Clinical Investigator, The Forsyth Institute, Boston, Massachusetts Adjunct Professor, Department of Conservative Dentistry and Periodontology, University of Munich Education:

M.S., 1979, University of Illinois, Chicago D.D.S. 1976, Autonomous University of Santo Domingo (Dominican Republic)


• Stem cell and tissue engineering • Biomaterials development and biocompatibility testing methods • Demineralization and remineralization • Dental erosion • Biofilm virulence

Research Funding:

• National Institutes of Health • Private Industry


• Feilzer AH, Frankenberg R, Garcia-Godoy F, Kramer N. Long-term degradation of enamel and dentine bonds:6-year results in vitro vs. un vivo. Dent Mat. 2010 Sept; 26(11).

• Garcia F, Murray PE, Garcia-Godoy F, Namerow KN. Effect of aquatine endodontic cleanser on smear layer removal in the root canals of ex vivo human teeth. J App Oral Sci. 2010 Aug;18(4):403-8.

• Ayad M, Maghrabi AA, Garcia-Godoy F. Resin composite polyethylene fiber reinforcement: Effect on fracture resistance of weakended marginal ridges. Am J Dent. 2010 Jun; 23(3):133-136

• Garcia-Godoy F, Kim HI, Kim YO, Ko CC, Kwon YH, Park SB, Son WS. Diode-pumped solid-state laser for bonding orthodontic brackets: effect of light intensity and light curing-time. Lasers Med Sci. 2010 Jun 8 [Epub ahead of print].

• Bahuleyan B, Chadipiralla K, Garcia-Godoy F, Huang CY, Murray PE, Stelnicki EJ, Yochim JM. Osteogenic differentiation of stem cells derived from human periodontal ligaments and pulp of human exfoliated deciduous teeth. Cell Tissue Res. 2010 May; 340(2):323-333.

• Alvarez-Serrano S, Garcia-Godoy F, Pameijer CH, Zmener O. Sealing Properties of a calcium alumniate agent. Am J Dent. 2010 Apr; 23(2): 121-124.


EDWARD F. HARRIS, PH.D. Professor, Department of Bioscience Research Professor, Department of Orthodontics Professor, Department of Pediatric Dentistry Education: NIH Postdoctoral Fellow, 1977-1980, University of Connecticut

Ph.D., 1977, Arizona State University, Tempe Office Phone: (901) 448-6265 Email: [email protected] Research Interests:

• Effects of age, sex, race, and environment on growth of the cranial complexes • Tooth mineralization • Tooth size, odontometrics • External apical root resorption

Research Funding:

• University of Tennessee College of Dentistry Alumni Endowment Fund Selected Publications:

• Harris EF, Mincer HH, Anderson KM, Senn DR. Age estimation from oral and dental structures. In: Senn DR, Stimson PG, editors. Forensic dentistry, 2nd ed. Boca Raton, FL: CRC Press, 2010, p. 263-303.

• Townsend GC, Harris EF, Lesot H, Clauss F, Brook AH. Morphogenetic fields within the human dentition: a new, clinically-relevant synthesis of an old concept. Arch Oral Biol. 2009;54(1):S34-S44.

• Harris EF. Interpreting heritability estimates in the orthodontic literature. Sem Ortho. 2008;14:125-134.

• Harris EF, Bodford K. Bilateral asymmetry in the tooth relationships of orthodontic patients. Angle Ortho. 2007;77:779-786.

• Harris EF. Carabelli’s trait and tooth size of human maxillary first molars. Am J Phys Anthro. 2007;132:238-246.

• Harris EF. Mineralization of the mandibular third molar: a study of American blacks and whites. Am J Phys Anthro. 2007;132:98-109.

• Harris EF. Dental Development and anomalies in craniosynostosis and facial clefting. In: Mooney MP, Siegel MI, editors. Understanding Craniofacial Anomalies: The Etiopathogenesis of Craniosynostosis and Facial Clefting. New York: John Wiley-Liss, 2002, p. 425-467.

• Harris EF. External apical root resorption resulting from orthodontic tooth movement. Sem Ortho. 2000;6:183-194.

• Harris EF. Dental maturation. In: Ulijaszek SJ, Johnston FE, Preece MA, editors. The Cambridge Encyclopedia of Human Growth. Cambridge: Cambridge University Press, 1998, p.45-48.


CHRISTOPHER NOSRAT, D.D.S., PH.D. Professor, Department of Bioscience Research Director of Oral Cancer, Center for Cancer Research (UTHSC) Professor, Department of Anatomy and Neurobiology, College of Medicine (UTHSC) Education:

Ph.D., 1997, Karolinska Institutet (Stockholm, Sweden) D.D.S., 1994, Karolinska Institutet (Stockholm, Sweden)


• Oral cancer and inflammation • Oral cancer stem cells • Dental pulp stem cells and biological tissue engineering • Oral neurobiology • Chemosensation • Genetics and genomics • Transgenic technology • Translational research

Research Funding:

• National Institutes of Health (NIH) • U.S. Department of Defense


• Rao SK, Pavicevic Z, Du Z, Kim JG, Fan M, Jiao Y, Rosebush M, Samant S, Gu W, Pfeffer LM, Nosrat CA. Pro-inflammatory genes as biomarkers and therapeutic targets in oral squamous cell carcinoma. J Biol Chem. 2010;285(42):32512-21.

• Ito A. Nosrat CA. Gustatory papillae and taste bud development and maintenance in the absence of TrkB ligands BDNF and NT-4. Cell Tissue Res. 2009;337:349-359.

• Wong DY, Hollister SH, Krebsbach PH, Nosrat CA. Poly (epsilon-Caprolactone) and Poly (L-Lactic-Co-Glycolic Acid) degradable polymer sponges attenuate astrocyte response and lesion growth in acute traumatic brain injury. Tissue Eng. 2007;13:2515-23.

• Nosrat IV, Smith CA, Mullally P, Olson L, Nosrat CA. Dental pulp cells provide neurotrophic support for dopaminergic neurons and differentiate into neurons in vitro; implications for tissue engineering and repair in the nervous system. Euro J Neurosci. 2004;19:2388-2398.

• Agerman K, Hjerling-Leffler J, Blanchard MP, Scarfone E, Canlon B, Nosrat CA, Ernfores P. BDNF gene replacement reveals multiple mechanisms for establishing neurotrophin specificity during sensory nervous system development. Development. 2003;130:1479-1491.

• Nosrat IV, Widenfalk J, Olson L, Nosrat CA. Dental pulp stem cells produce neurotrophic factors, interact with trigeminal neurons in vitro and rescue motoneurons after spinal cord injury. Develop Biol. 2001;238:120-132.

•


MARK SCARBECZ, M.A., PH.D. Director, Planning and Assessment Professor, Department of Bioscience Research Faculty (Dental Science), College of Graduate Health Sciences Education: Ph.D., 1991, University of Arizona, Tucson M.A., 1983, University of Arizona, Tucson B.A., 1981, University of New York at Buffalo Office Phone: (901) 448-1211 Email: [email protected] Research Interests:

• Demographic trends in the dental profession • Women in the dental profession • Dentist-patient relations • Relationship between subjective general health and subjective oral health • Scholarship of Teaching and Learning (SoTL)

Research Funding:

• None at present Selected Publications:

• Bland PS, Patters MR, Scarbecz M, Shiloah J, Stein SH, Tipton DA. The effect of long-term aspirin intake on the outcome of non-surgical periodontal therapy in smokers. J Dent Res. 2010 Special Issue.

• Brescica W, Hofmann P, Robinson MM, Russell CK, Scarbecz M, Sheid C, Scwab C, Shreve R. Assessing teaching activities on an academic health science center campus. Trans Dialog: Teaching and elearning. 2010 Mar;3(3).

• Redmond DC, Scarbecz M. Dental practice transition: A practical guide to management (Book Review). J Dent Edu. 2009 Dec; 73:1423-1424.

• Chaudhry J, Chaudhry S, Scarbecz M, Thomas R. Efficacy of high-resolution digital bitewings in diagnosing incipient proximal caries. J Dent Res. 2009; 88(Spec Iss A): 3346.

• Donaldson ME, Gala A, Scarbecz M. Caries risk assessment in restorative pediatric dentistry. J Dent Res. 2009;89(Spec Iss A): 2524.

• Scarbecz M. Critical Thinking, Understanding, and Evaluating Dental Research, 2nd ed. (Book Review). J Dent Edu. 2008 Oct;72(10): 1209-1210.

• Gilpatrick RO, Harrison JA, Scarbecz M, Simon JF, Welk A, Wicks RA. Evaluation of the optimized integration of computer-assisted learning and simulation with 40 DentSim units into existing curriculum. Intl J Comput Dent. 2008;11:17-40.

• Scarbecz M. Evidence-based dentistry resources for dental practitioners. J Tenn Dent Assoc. 2008 Spring;88(2):9-13.

• Gilpatrick RO, Harrison JA, Maggio MP, Scarbecz M, Simon JF, Welk A, Wicks RA. Computer-assisted learning and simulation lab with 40 DentSim units. J Comput Den. 2008;11(1):17-40.

• Chaudhry J, Mincer HH, Scarbecz M. Cone-beam computed tomography analysis of alveolar canal location. J Dent Res. 2008;87(Spec Iss A): 0867.


EDWIN L. THOMAS, M.S., PH.D. Professor, Department of Bioscience Research Professor, Department of Microbiology, Immunology, and Biochemistry Education: Ph.D., 1970, University of Michigan, Ann Arbor M.S., 1966, University of Michigan, Ann Arbor Office Phone: (901) 448-4879 Email: [email protected] Research Interests:

• Innate immunity • Antimicrobial peptides of saliva, leukocytes, and epithelial cells • Peroxidase enzymes of leukocytes and saliva • Proteomics and biomarkers of human disease • Calcium-binding molecules and resistance of the teeth to damage by acid

Research Funding:

• University of Tennessee College of Dentistry Alumni Endowment Fund Selected Publications:

• Dabbous MK, Jefferson MM, Haney L, Thomas EL. Biomarkers of metastatic potential in cultured adenocarcinoma clones. Clin Exp Metastasis. 2010 [In Press].

• Tipton DA, Pabst MJ, Thomas EL, Babu JP, Stein SH, Fry H. Association of high plaque levels of Prevotella intermedia with aggressive periodontitis in a 16-year-old female. Perio. 2006;3:115-122.

• Thomas EL, Jefferson MM, Learn DB, King CC, Dabbous MK. Myeloperoxidase-catalyzed chlorination of histamine by stimulated neutrophils. Redox Reports. 2000;5:191-194.

• King CC, Jefferson MM, Thomas EL. Secretion and inactivation of myeloperoxidase by isolated neurophils. J Leukocyte Biol. 1997;61:293-302.


DAVID A. TIPTON, D.D.S., PH.D. Professor, Department of Bioscience Research Professor, Department of Periodontology Education: Ph.D., 1988, University of Memphis D.D.S., 1978, University of Tennessee College of Dentistry B.A., 1975, Vanderbilt University Office Phone: (901) 448-7200 Email: [email protected] Research Interests:

• MMPs and inflammatory mediators in periodontal and TMJ disease • Effects of drugs and natural products on soft tissue cell production of

mediators of bone metabolism • Cellular response to anti-inflammatory drugs and natural products • Gingival fibroblast production/regulation of ECM molecules and MMPs in gingival fibroses • Cellular response to dental biomaterials

Research Funding:

• Private industry • University of Tennessee College of Dentistry Alumni Endowment Fund


• Tipton DA, Seshul BS, Dabbous MKh. Effect of bisphosphonates on the production of mediators of osteoclastogenesis (RANKL, OPG, and IL-6) by human gingival fibroblasts. J Periodont Res 2010; (Article online in advance of print) doi:10.1111/j.1600-0765.2010.01306.x

• Tipton DA, Legan Z, Dabbous MKh. Methamphetamine cytotoxicity and effect on LPS-stimulated IL-1β production by human monocytes. Toxicol In Vitro 2010; 24: 921-927.

• Tipton DA, Pond DM. Effect of NF-κB inhibition on IL-1β-stimulated MMP-3 production by gingival fibroblasts from a patient with aggressive periodontitis. PERIO 2008; 5:187-196.

• Tipton DA, Lewis JL. Effects of a hindered amine light stabilizer (HALS) and a UV light absorber (UVA) used in maxillofacial elastomers on human gingival epithelial cells and fibroblasts. J Prosth Dent 2008; 100:220-231.

• Tipton DA, Gay D, DeCoster V. Effect of a COX-2 inhibitor on IL-1β-stimulated activation of the transcription factor NF-κB in human gingival fibroblasts. J Periodontol 2007; 78:542-549.

• Tipton DA, Pabst MJ, Thomas EL, Babu JP, Stein SH, Fry H. Association of high levels of Prevotella intermedia with aggressive periodontitis in a 16-year-old female. PERIO 2006; 3:115-122.

• Tipton DA, Hamman NR, Dabbous MKh. Effect of myrrh oil on IL-1β stimulation of NF-kB activation and PGE2 production in human gingival fibroblasts and epithelial cells. Toxicol In Vitro 2006; 20:248-255.


ANTHEUNIS VERSLUIS, PH.D. Director, Biomaterials Professor, Department of Bioscience Research Education: Ph.D., 1994, University of Greenwich, London Ingenieur, 1988. Delft University of Technology, Delft, The Netherlands Office Phone: (901) 448-6263 Email: [email protected] Research Interests:

• Biomechanics (stress-strain analysis) applied to dental tissues, such as:

o Restoration techniques o Polymerization shrinkage and hygroscopic expansion o Wear, failure, fracture, and fatigue of teeth, restorations, roots, and instruments o Orthodontic forces and tooth movement o Testing methods used in dental research

Research Funding:

• Private Industry Selected Publication

• dos Santos AFV, Meira JBC, Tanaka CB, Xavier TA, Ballester RY, Lima RG, Pfeifer CS, Versluis A. Can fiber posts increase root stresses and reduce fracture? J Dent Res. 2010;89:587-597.

• Kim HC, Lee MH, Yum J, Versluis A, Lee CJ, Kim BM. Potential relationship between design of NiTi rotary instruments and vertical root fracture. J Endodont. 2010;36:1195-1199.

• Boaro LCC, Gonvalves F, Guimaraes TC, Ferracane JL, Versluis A, Braga RR. Polymerization stress, shrinkage, and elastic modulus of current low-shrink restorative composites. Dent Mater. 2010;26:1144-1150.

• da Silva NR, Raposo LHA, Versluis A, Soares CJ. The effect of post, core, crown type, and ferrule presence on the biomechanical behavior of endodontically treated bovine anterior teeth. J Prosthet Dent. 2010;104:306-3017.

• Kanjanaouthai A, Mahatumarat K, Techalertpaisarn P, Versluis A. The effect of inclination of a maxillary central incisor on the moment to force ratio: finite element method. J Thai Assoc Orthodont. 2010;9:24-32.

• Parco TM, Tantbirojn D, Versluis A, Feigal RJ, Beiraghi S. Microleakage of self-etching sealant on non-contaminated and saliva-contaminated enamel. Pediat Dent. 2010;in press.

• Hur B, Kim HK, Park JK, Versluis A. Characteristics of noncarious cervical lesions – an ex vivo study using micro computed tomography. J Oral Rehab. 2010;in press.

• Versluis A, Tantbirojn D, Lee MS, Tu LS, DeLong R. Can hygroscopic expansion compensate polymerization shrinkage? Part I: Deformation of restored teeth. Dent Mater. 2010;in press.

• Meira JBC, Braga RR, Ballester RY, Tanaka CB, Versluis A. Understanding contradictory data in contraction stress tests. J Dent Res. 2010;in press.

• Tantbirojn D, Chongvisal S, Augustson DG, Versluis A. Hardness and post-gel shrinkage of preheated composites. Quint Intl. 2010;in press.


DENTAL RESEARCH STAFF

ADMINISTRATION Nancy Turner

Administrative Aide [email protected] (901) 448-6333 Laurel Wedel, M.A. Grants & Clinical Research Coordinator [email protected] (901) 448-2210 BIOMATERIALS RESEARCH CENTER Nancy Pecora, B.S.C., B.A., M.B.A. Research Coordinator [email protected] (901) 448-6263 BIOSCIENCE RESEARCH CENTER Yanhui Zhang, Ph.D. Research Associate [email protected]

(901) 448-6333 CANCER RESEARCH CENTER Irina Vukmanovic Nosrat, D.D.S. Research Team Leader [email protected] (901) 448-1254 Shailaja Kishan Rao, Ph.D. Post-Doctoral Research Fellow [email protected] (901) 448-1963 Michelle Sims, B.S. Research Coordinator [email protected] (901) 448-2151

CLINICAL RESEARCH CENTER Kimberly S. DeMonaco, R.D.H. Clinical Research Associate [email protected] (901) 448-2794 CRANIOFACIAL RESEARCH CENTER Margaret Jefferson Sr. Research Assistant [email protected] (901) 448-6058 Iva Pendleton Admin. Service Assistant [email protected] (901) 448-6167 Geraldine Moore Lab Assistant [email protected] (901) 448-6167 TMD/SLEEP DISORDER CLINIC Brandy Clark, CDA, RDA Clinical Dental Assistant [email protected] (901) 448-1285 Linda Vincent Clinic Coordinator [email protected] (901) 448-1285














The following is a list of funded research faculty. The first section lists all faculty who hold federal, industrial, or foundation research grants. The second section lists all faculty who hold Dental

Alumni research grants. Contact information and project titles are provided.

PART B: Funded Research Faculty

The following is a list of faculty members who are principal investigators on federal, industrial, or foundation research grants. Titles, sponsors, expirations, and abstracts are provided for each grant. Faculty are listed alphabetically by last name.

JEGDISH BABU, B.S., M.S., PH.D. Professor, Department of Bioscience Research

Phone: (901) 448-4342 Email: [email protected]

Influence of cranberry juice components on denture related stomatitis and inflammatory reactions of gingival fibroblasts Sponsor: Cranberry Institute of Wisconsin Until: July 31, 2011 Abstract: This study investigates the role of high molecular weight components

isolated from cranberry juice in the prevention of fungal biofilm formation on denture material. Additionally, the study also focuses on suppression of highly inflammatory cytokines and metalloproteinases by human gingival fibroblasts.

JOEL BUMGARDNER, PH.D. Adjunct Professor, Department of Bioscience Research Associate Professor, Joint Biomedical Engineering Program – UTHSC and University of Memphis Phone: (901) 678-5253 Email: [email protected]

Dual delivery of growth factors and/or antibiotics from chitosan-composites for bone regeneration Sponsor: Department of the Army, US Army Medical Research Program Until: September 30, 2010 Abstract: Development of a chitosan calcium sulfate resorbable dual delivery

vehicle for antibiotics and growth factors to prevent infection and stimulate healing in catastrophic orthopedic injuries.

FEDERAL, INDUSTRIAL, FOUNDATION Grants



FRANKLIN GARCIA-GODOY, D.D.S., M.S. Senior Executive Associate Dean, UTHSC College of Dentistry Chair, Department of Bioscience Research Director, Bioscience Research Center Professor, Department of Physiology, UTHSC Adjunct Professor, Dept. of Biomedical Engineering, University of Memphis Adjunct Professor, Dept. of Biomedical Engineering, Florida International University Senior Clinical Investigator, The Forsyth Institute, Boston Adjunct Professor, Department of Conservative Dentistry and Periodontology, University of Munich Phone: (901) 448-6333 Email: [email protected]

The biocompatibility screening of restorative treatments Sponsor: NIH – NIDCR (R56) Until: August 31, 2011 Abstract: The goal of this study is to screen the biocompatibility of restorative

dental treatments. A study to assess the effects of glycolysis and regrowth activity of three marketed mouth rinses compared to a negative control Sponsor: P&G Until: Spring 2011 Abstract: Validation clinical trial to test three mouth rinses compared to a

negative control.

LIANG HONG, D.D.S., M.S., PH.D. Associate Professor, Department of Pediatric Dentistry and Community Oral Health Director, Community Oral Health Phone: (901) 448-6206 Email: [email protected]

Development of miniature plasma brush for dental clinical applications Sponsor: NIH-NIDCR (R44 – SBIR Phase II) Until: June 30, 2012 Abstract: The main objective of this project is to develop a miniature

atmospheric cold plasma brush (m-ACPB) for dental clinical applications.



ADAM LLOYD, B.D.S., M.S. Assistant Professor, Department of Endodontics


Visualization of sealer movement during single-cone obturation with EndoSequence BC Sealer

Sponsor: Real World Endodontics/Brasseler USA Until: N/A Abstract: Assess movement of a bioceramic sealer into the intricacies of root

canal anatomy during single-cone obturation.

CHRISTOPHER NOSRAT, D.D.S., PH.D. Professor, Department of Bioscience Research


Neurotrophin specificity and function in the taste system Sponsor: NIH-NIDCD (R01) Until: June 30, 2011 Abstract: Investigation of the roles of neurotrophins, and in particular, BDNF

during development and in the adult taste system. Working to generate and analyze novel transgenic mice as part of this study.

Neurotrophin specificity and function in the taste system Sponsor: NIH-NIDCD ARRA Supplement to R01 Until: March 31, 2011 Abstract: Analyzing taste transgenic mice using laser capture micro-dissected

taste tissue, microarray analysis and bioinformatics.



DAVID A. TIPTON, D.D.S., PH.D. Professor, Department of Bioscience Research Professor, Department of Periodontology


Influence of cranberry components on gingival epithelial cell production of bone resorptive mediators and adherence of periodontopathogens Sponsor: The Cranberry Institute of Wisconsin Until : (pending) Abstract: The goals of this study are to determine whether cranberry NDM

interferes with aspects of pathogenesis of periodontitis, namely inhibition of adherence of periodontopathogens to human gingival epithelial cells, and LPS-stimulated gingival epithelial cell production of molecules that degrade, or promote degradation, of periodontal bone


The following is a list of active UT Dental Alumni Endowment Grants. Projects are listed alphabetically by title, with faculty names and email addresses , and project expirations.

A comparison of the effects of occlusal adjustment and splint therapy on symptoms reduction in TMD

Investigator(s):

SWATI AHUJA, B.D.S., M.D.S., D.D.S. Assistant Professor, Department of Prosthodontics


DAVID CAGNA, D.M.D., M.S. Director, Graduate Prosthodontics Professor, Department of Prosthodontics


Project Period Ends: June 2012

UT DENTAL ALUMNI ENDOWMENT FUND Grants



An ultra-structural evaluation of the resin-dentin bond in root canals conditioned with phosphoric acid and ethylenediamine tetra-acetic acid

Investigator(s):

PETER DIFIORE, D.D.S. Chair and Professor, Department of Endodontics Phone: (901) 448-6618 Email: [email protected] JEFF PHEBUS, D.D.S. Assistant Professor, Department of Endodontics Phone: (901) 448-6438 Email: [email protected]

Project Period Ends: April 2011



Can dental students be trained to read dental radiographs for osteoporosis

screening?

Investigator(s):

JOHN COVINGTON, D.D.S., M.S. Chair and Professor, Department of Biologic & Diagnostic Sciences Phone: (901) 448-8609 Email: [email protected] CESAR MIGLIORATI, D.D.S., M.S., PH.D. Professor, Department of Biologic & Diagnostic Sciences Director, Division of Oral Medicine Phone: (901) 448-2613 Email: [email protected]

Project Period Ends: February 2011



Differences between adults and adolescents in RANKL and osteoprotegerin

levels response to orthodontic force

Investigator(s):

EDWARD HARRIS, PH.D. Professor, Department of Bioscience Research Professor, Department of Orthodontics Phone: (901) 448-6265 Email: [email protected] DAVID TIPTON, D.D.S., PH.D. Professor, Department of Bioscience Research Professor, Department of Periodontology Phone: (901) 448-7220 Email: [email protected]




Distribution and osteogenic potential of mesenchymal stem-like periodontal ligament cells in periodontal health and disease

Investigator(s):

ANASTASIOS KARYDIS, D.D.S., M.S., PH.D. Assistant Professor, Department of Periodontology


SWATI RAWAL, B.D.S., M.D.S., M.S. Director, Graduate Periodontics Assistant Professor, Department of Periodontology


YESHWANT RAWAL, B.D.S., M.D.S., M.S. Assistant Professor, Department of Biologic & Diagnostic Sciences


JACOB SHILOAH, D.D.S., D.M.D. Professor, Department of Periodontology


DAVID A. TIPTON, D.D.S., PH.D. Professor, Department of Bioscience Research Professor, Department of Periodontology


Project Period Ends: August 2011






Evaluation of three-point flexural strength, maximum flexural loading and

flexural modulus, under thermal cycling, of extracted endodontically prepared human teeth using a prefabricated glass fiber reinforced composite post system

Investigator(s):

ADAM DAVIS, D.D.S. Instructor, Department of Endodontics

Phone: N/A Email: N/A

BARRY MARK OWENS, D.D.S. Associate Professor, Department of Restorative Dentistry


JEFF PHEBUS, D.D.S. Assistant Professor, Department of Endodontics


Project Period Ends: October 2011

No

Photo

Available



Geographic Variability in the Tempos of Tooth Formation in the United States

Investigator(s):

EDWARD HARRIS, PH.D. Professor, Department of Bioscience Research Professor, Department of Orthodontics


Project Period Ends: May 2011

Invited Lectureships in Prosthodontics Investigator(s):

DAVID CAGNA, D.M.D., M.S. Director, Graduate Prosthodontics Professor, Department of Prosthodontics





SECTION II: Students in Research

STUDENTS IN Dental Research

The College of Dentistry uses a variety of tools to improve human oral health, two of which are education and research. In recent years, the College has worked to expand its student research opportunities, creating an overlap between education and research, and helping students to better prepare for their future in dentistry. Whereas research is more common in post-doctoral and residency programs, in the pre-doctoral program, there are many opportunities for students to enjoy research training and receive hands-on experience conducting research in one of the dental research laboratories and clinics on campus (for a list of Dental Research Centers, please refer to page 7). For most UT dental students, the first opportunity to get involved in research will be during the summer after the first year of dental school (end of D1). During this summer session, students will have the most time to dedicate to research. However, limited time is also available at the end of the second year (D2) with varying amounts of additional time allotted in the following year to writing abstracts and presenting posters at meetings (such as the Hinman Student Research Symposium and IADR/AADR annual meetings). For students in their third and fourth year (D3 and D4) who are interested in participating in research, individual research electives can also be arranged for the duration of one semester. In regards to funding for research, a modest stipend is available for a limited number of students to participate in the Student Summer Research Program, which is funded by the UT Dental Alumni Research Training Award (see Alumni Research Training Award section for more information about this program). Students are encouraged to apply for private and federal grants and fellowships as well.

FOR STUDENTS in Dental Research

At the University of Tennessee College of Dentistry (CoD), student research is a highly valuable scholarly activity, viewed as an integral component of the academic experience. Therefore, College administrators make it a priority to provide students with a variety of research opportunities, and, starting at new student orientation, faculty stress the important of engaging in research during at least one of the four years on campus. The CoD Student Research Program for pre-doctoral students provides funding for student research projects. This program was initiated in 1974, at which time limited funding was available to two students through the L.G. Noel Foundation. Over the next several years, interest in this program grew and attracted 18-20% o f incoming students each year. To provide more funded research opportunities and promote student participation in research, College administrators established the Summer Research Training Program. This program was supported by an NIH training grant awarded to UT CoD by the National Institute of Dental and Craniofacial Research (NIDCR). This T35 grant continued for ten years before it was phased out in 2005. In the wake of the loss of NIDCR funding, the UT Dental Alumni Association, in recognizing the importance of this student research program, committed funds for the Summer Student Research Training Program, for a period of ten (10) years. This current program for pre-doctoral students has been described by reviewers at NIDCR as a “model program” for other dental schools. This program provides stipends for ten (10) dental students per year. During the summer, students receiving funding will engage in individualized research projects under the guidance and expertise of a faculty investigator who specializes in basic science, clinical science, or translational research. Students will work with their faculty mentor in his/her laboratory or clinic for the duration of eight (8) to ten (10) weeks. After this time, students will be required to present their research data in an oral presentation to their colleagues, faculty, and dental alumni. Student researchers will also be encouraged to present their research at national and international forums (including AADR/IADR meetings and the Hinman Student Research Symposium). All student researchers will be required to present their research as table clinics or posters at the annual Student Research Day held on campus each February.

STUDENT RESEARCH Training Program

DETAILS OF THE PROGRAM:

The Alumni Student Research Training program provides an opportunity for dental students to participate in cutting edge research experiences. The research training which the students receive individually allows the students to have an excellent opportunity for professional and academic growth, and it introduces students to different career opportunities in dental research and academic dentistry. DETAILS ON THE PROGRAM: Stipend: $1,200 per month* Duration: 1-2 months (summer) Eligibility: Any UTHSC dental student in good academic standing Application: Available in the Craniofacial or Bioscience Research Center Deadline: Annually by February 1st FOR MORE INFORMATION, PLEASE CONTACT: Craniofacial Research Center (901) 448-6167 - Or - Bioscience Research Center (901) 448-6333 _________________________________________________________________________________________________________ * A travel allowance will be provided to students for presenting their abstracts at the AADR/IADR annual meetings.

SELECTING A RESEARCH MENTOR:

The first step to engaging in research in the College of Dentistry is to explore research topics and project ideas. It is important to find research that not only has practical value, but also fascinates you. Keep in mind that it is not necessary to narrow your interests to one specific topic – your faculty research mentor can help you further develop the details of your research proposal. In order to find a faculty research mentor whose interests align with your own, use these hints for selecting a research mentor:

1) Review Section I: Faculty in Bioscience Research of this handbook. Faculty who are currently engaged in research are listed alphabetically with a brief synopsis of their research interests. Thoroughly read through each individual’s research interests and use the contact information provided to set a meeting to discuss your interests further. Also, review the list of the previous summer’s mentors for your potential mentor.

2) Set up a consultation with Dr. Franklin Garcia-Godoy, Senior Executive Associate Dean for Research (901-448-6333 or [email protected]), to discuss your research interests and receive feedback from him regarding the feasibility of your research topic and suggestions for which faculty might best serve as your mentor.

3) Talk to a D2, D3, or D4 student and ask for references. Seek out those students who have participated in the program in previous years.

4) Talk to your faculty, particularly those for the classes that you enjoy or in areas where you feel your interests reside.

5) Do a little background research into your topic; read journal articles related to your topic and arm yourself with support for your research.


2010 STUDENT SUMMER RESEARCH MENTORS:

JEGDISH BABU, B.S., M.S., PH.D. Professor, Department of Bioscience Research Phone: (901) 448-4342 Email: [email protected]

BERNARD BLEN, D.D.S. Assistant Professor, Department of Restorative Dentistry Phone: (901) 448-4489 Email: [email protected]

MUSTAFA KH. DABBOUS, PH.D. Professor, Department of Bioscience Research Professor, Department of Molecular Sciences Phone: (901) 448-6167 Email: [email protected]

LAURA DARNELL, D.M.D., PH.D. Assistant Professor, Department of Restorative Dentistry Phone: (901) 448-6271 Email: [email protected]





FRANKLIN GARCIA-GODOY, D.D.S., M.S. Senior Executive Associate Dean for Research Phone: (901) 448-6333 Email: [email protected]

JANET HARRISON, D.D.S.

Chair and Professor, Department of Restorative Dentistry Phone: (901) 448-6692 Email: [email protected]

ROBERT HATCH, D.D.S. Assistant Professor, Department of Restorative Dentistry Phone: (901) 448-4489 Email: [email protected]

WAINSCOTT HOLLIS, D.D.S. Assistant Professor, Department of Prosthodontics Phone: (901) 448-6288 Email: [email protected]





SWATI RAWAL, B.D.S., M.D.S., M.S.

Assistant Professor, Department of Periodontology Director, Graduate Periodontics Phone: (901) 448-1963 Email: [email protected]

JAMES SIMON, D.D.S. Professor, Department of Restorative Dentistry Director, Esthetic Dentistry Phone: (901) 448-6641 Email: [email protected]

EDWIN L. THOMAS, B.A., M.S., PH.D. Professor, Department of Bioscience Research Phone: (901) 448-4879 Email: [email protected]

DAVID A. TIPTON, D.D.S., PH.D. Professor, Department of Bioscience Research Professor, Department of Periodontology Phone: (901) 448-7220 Email: [email protected]





WALETHA WASSON, D.D.S.

Associate Professor, Department of Restorative Dentistry Phone: (901) 448-6910 Email: [email protected]


STEPS TO FOLLOW:

Now that you know that you want to participate in research, follow the steps listed below to begin the process:

1) Make an appointment with the Senior Executive Associate Dean for Research, Dr. Franklin Garcia-Godoy, to discuss research interests and possible faculty mentors.

2) Contact the Grants & Clinical Research Manager (448-2210) or the Craniofacial Research Center (448-6167) to pick up the application guidelines.

3) Call your prospective mentor to arrange for a meeting to discuss your interest in research and ask him/her for input on research topics. This should be completed between September and January before the summer in which you want to do research.

4) Work with your mentor to develop a simple proposal.

5) Submit your application by February 1st (annually).

6) An ad hoc committee will review all applications and will choose the ten (10) grant recipients according to the follow criteria:

• Scientific merit • Feasibility of project completion during project period • Clarity and conciseness

7) Award notifications will be sent by March 15th (annually).

8) For those who receive an award: You will be responsible for arranging the start date with your mentor and the schedule for your summer research – make sure to build flexibility into that schedule and keep in consideration major holidays and/or vacations.

The College of Dentistry hosts an annual Student Research Day, which provides dental students, who are engaged in research projects, with an opportunity to present their work on a local platform. Classes are canceled and the clinics are closed in the afternoon to encourage all students and faculty to attend the event and benefit from a rich, educational experience.

The annual event is held in mid-February, in the Schreir Auditorium, located in the Students Activity Center (SAC) on Madison Avenue.

The program includes a key note lecture by a world-class speaker in Oral Translational Research. The lecture is followed by an afternoon of presentations. Students may choose to present their work in table clinic or poster form.

Presentations are judged by a panel of faculty and alumni representatives. Students compete for several honors to be awarded.

Honors include:

• The Student Clinician Award for the Most Outstanding Presentation (sponsored by Dentsply/ADA)

The student who receives this honor will be awarded a trip to the ADA annual meeting to present his/her research project

• The Harold Cloogman Award for the Best Summer Research Program project • The James C. Ragain Awards for Student Summer Research Program projects in 2nd,

3rd, 4th, and 5th places.

Also presenting at the Student Research Day are Graduate Medical Education Students. These advanced students will compete for the Graduate Program Research Award.

STUDENT Research Day

The Hinman Student Research Symposium was established in 1995 to highlight student achievements in research. The Hinman is co-sponsored by the Thomas P. Hinman Dental Society and the University of Tennessee College of Dentistry, with participation of the National Institute of Dental and Craniofacial Research, the ADEAGies Foundation, the Procter & Gamble Company, Colgate, and the Tennessee Dental Association Foundation. The Hinman Student Research Symposium is held every year at the Historic Peabody Hotel in Memphis, which is centrally located in the Mid-South, right along the Mississippi. The Symposium consists of competitive, scientific sessions with awards for the best presentations, a banquet with a nationally acclaimed key-note speaker, exhibits, and numerous networking opportunities as well as touring the “beautiful Bluff City.” The Hinman begins on a Friday at noon, consisting of registration and poster set-up. This is followed by a reception and welcome banquet. The Symposium continues on Saturday with both morning and afternoon scientific sessions and many opportunities for fun and more networking. But the Hinman isn’t all academia. Following a tour of Elvis Presley’s Graceland Mansion, you’ll be on your own for the evening on Beale Street, “Home of the Blues.” On Sunday, the scientific sessions will continue in the morning and close with the presentation of awards. Outside of the Hinman Student Research Symposium, and the activities listed above, Memphis offers many more opportunities for exploration – from the Pyramid to Sun Studios to boat tours on the Mississippi to the lesser known but worthwhile National Civil Rights Museum, Pink Palace Museum, Brooks Art Gallery, Dixon Gardens, and the unique Ornamental Metal Museum. Tree-shaded parks and neighborhoods, good food, and warm Southern hospitality await you. For further information, please visit the Hinman Symposium online at: www.uthsc.edu/dentistry/admission/hinman

HINMAN STUDENT Research Symposium

http://www.uthsc.edu/dentistry/admission/hinman�

THE HISTORIC PEABODY HOTEL MEMPHIS, TN

PRESENTATIONS at the Hinman

HINMAN STUDENT RESEARCH SYMPOSIUM OCTOBER 29-31, 2010

January 2011

THE UNIVERSITY of TENNESSEE

HEALTH SCIENCE CENTER

College of Dentistry

875 Union Avenue

Memphis, TN 38163-0001

(901) 448-6200

Edited by Laurel Wedel, M.A. Communications Specialist Grants & Clinical Research Coordinator

uthsc dental research handbook

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