utilizing topolyzer vario & oculyzer ii for accurate refractive

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ROC Science to Innovation AG echnoparkstrasse 1 005 Zürich el: +41 43 500 0850 We focus your ideas Utilizing TopolyzerVario & Oculyzer II for accurate refractive outcomes Michael Mrochen, PhD

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Topography guided LASIK, PRK, Pentacam, Oculyzer, Topolyzer, WaveLight, alcon

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Page 1: Utilizing topolyzer vario & oculyzer ii for accurate refractive

IROC Science to Innovation AG Technoparkstrasse 18005 ZürichTel: +41 43 500 0850

We focus your ideas

Utilizing TopolyzerVario & Oculyzer II for accurate refractive outcomes

Michael Mrochen, PhD

Page 2: Utilizing topolyzer vario & oculyzer ii for accurate refractive

VISION - OPTICS - LIGHTVISION - OPTICS - LIGHT

Content

• What essential data are required by your ex500?• What is different between WFO and T-CAT?• A limiting factor: the subjective refraction• Accuracy of the TopolyzerVario• Accuracy of the Oculyzer II• A small pocket guide on: What to use when?

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Page 3: Utilizing topolyzer vario & oculyzer ii for accurate refractive

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What essential data are required by your ex500?

• Ablation profile– A map of required tissue removal at each point of the

cornea – It’s based on difference between the pre- and to post-

operative cornea anterior surface– Derived from either modelled or measured anterior

cornea data

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Page 4: Utilizing topolyzer vario & oculyzer ii for accurate refractive

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What essential data are required by your ex500?

• How to calculate an ablation profile?– Assume a preoperative cornea shape (R,Q, Cyl,…)– Calculate the postoperative corneal shape based on the

attempted refractive power change– Define to optical zone– Calculate the change in corneal height maps within the

optical zone– Define a transition zone

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Preoperative

Postoperative

Optical zone

Page 5: Utilizing topolyzer vario & oculyzer ii for accurate refractive

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What is different between WFO and T-CAT?

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Ex500Algorithm

WFO Wavefront Optimized for sphere and cylinder

Manifest Refraction

Optical zone

WFOAblation profile

- Refractive predictability- Maintain visual performance

Ex500Algorithm

T-CAT Topography guided for sphere, cylinder and corneal irregularities

Manifest Refraction

Optical zoneT-CAT

Ablation profile

- Refractive predictability- Improve visual performanceHeight maps from

Topolyzer / Oculyzer

Page 6: Utilizing topolyzer vario & oculyzer ii for accurate refractive

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A limiting factor: the subjective refraction

Thomas W. Raasch1, Kenneth B. Schechtman2, Larry J. Davis3, Karla Zadnik1 Repeatability of subjective refraction in myopic and keratoconic subjects: results ofvector analysis. Ophthal. Physiol. Opt. Vol. 21, No. 5, pp. 376±383, 2001

Error of refraction (normal eyes)

60% [43% to 75%] ±0.2592% [80% to 98%] ±0.5100% [91% to 100%] ±1.0

Error of refraction (irregular cornea)

25% [18% to 33%] ±0.2550% [41% to 58%] ±0.580% [72% to 86%] ±1.0

Page 7: Utilizing topolyzer vario & oculyzer ii for accurate refractive

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Accuracy of the TopolyzerVario

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44Edges

Edge Detection

Page 8: Utilizing topolyzer vario & oculyzer ii for accurate refractive

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Accuracy of the TopolyzerVario

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Eye lashes, lid & nose Corneal irregularities

Pupil detection Corneal surface / tear film

Page 9: Utilizing topolyzer vario & oculyzer ii for accurate refractive

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Degree of light scattering is of clinical relevance

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Accuracy of the Oculyzer II

Page 10: Utilizing topolyzer vario & oculyzer ii for accurate refractive

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Accuracy of the Oculyzer II

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Segmented measurement Motion compensation

Light scattering

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Consequences of accuracy

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Uncertainty of topography ~ 2 - 5 microns @ 8 mm

2 micrometer will result in an uncertainty of approximately 0.14 D for an optical zone of 6.5 mm

2 micrometer will result in an uncertainty of approximately 0.98 D for an optical zone of 2.5 mm

Page 12: Utilizing topolyzer vario & oculyzer ii for accurate refractive

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A small pocket guide on: What to use when?

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Manifest Refraction

How much can I trust the Rx?

TopolyzerVarioMeasurement

Oculyzer IIMeasurement

Mires of rings well detected?

Scheimpflug images well detected?

Yes

Successful Topolyzer or

Oculyzer measurement?

Noex500

Yes

NoOther treatment

options

Page 13: Utilizing topolyzer vario & oculyzer ii for accurate refractive

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Summary

• TopolyzerVario and Oculyzer II are accurate measurement devices as demonstrated by experimental measurements and clinical studies.

• Measurements of each device can be affected differently by the condition of the patient’s eye.

• Raw data checks are required to assure accurate measurements.

• Consequences can be irregular ablations or poor refractive predictability

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