c h a n g i n g t h e c o u r s e o f

research, discovery and hope.

David and Carol Van Andel

Jason Dunn and Brooke

Dr. Lena Brundin

Dr. Nathan Lanning and Duncan Lake Middle School

Dr. Matt Steensma and Nathaniel

A N N u A L r e p o r t 2 0 1 3

Dr. Jeff MacKeigan

Through biomedical research and science education,

Van Andel Institute is committed to improving the health

and enhancing the lives of current and future generations.

o u r m i s s i o n

3 A Letter from David Van Andel

5 Changing the Course of Research

7 Center for Neurodegenerative Science

9 Center for Cancer and Cell Biology

11 Center for Skeletal Disease and Tumor Metastasis

13 Center for Translational Medicine

15 Changing the Course of Discovery

17 Science Academy

19 Van Andel Institute Graduate School

21 Changing the Course of Hope

23 Purple Community®

27 Signature Special Events

31 Donor Recognition

35 Tributes

37 Memorials

41 Purple Community Events

42 Signature Special Event Sponsors

43 Leadership Team

44 Board and Council Members

t a b l e o f c o n t e n t s

v a n a n d e l i n s t i t u t e 2

In a word, grateful.

That’s the best way to express how my wife Carol and I – and everyone else affiliated with Van Andel Institute – feel. And it’s because of generous people just like you.

Our dedicated scientists and educators work long and difficult hours to unravel the mysteries behind catastrophic illness and disease. But none of it would be possible without the gracious support of friends and supporters who share our vision, our mission… our hearts.

The good news is that with your help, we can stop diseases like cancer and Parkinson’s.

a l e t t e r f r o m d a v i d v a n a n d e l

It’s been nearly 20 years since my late parents, Jay and Betty Van Andel, undertook the ambitious mission to create a world-class biomedical research and science education organization in Grand Rapids. It not only succeeded, but it is flourishing, thanks in large part to you – a community of people committed to improving the health and enhancing the lives of current and future generations.

There is no time to wait. Cancer alone kills some 570,000 Americans annually – the equivalent of a mid-sized city. The good news is that with your help, we can stop diseases like cancer and Parkinson’s.

We are not patient in our quest to change the very course of humanity. We are geared to perform faster and more efficiently. And we are eager to collaborate with other specialists all over the globe to make it happen sooner.

G I V e t o D A Y A t V A I . o r G / G I V e3

Van Andel Institute is moving quickly, accelerating our efforts in a complex pursuit to improve patient outcomes. Our research is not always easy to understand, and we invite you to come spend time with us and learn more about the important progress happening here.

When supporters like you talk with our people, they walk away inspired about the possibilities, optimistic about the future, and energized about partnering with us to save lives. They embrace Van Andel Institute as a transforming beacon of hope, and they are motivated to go to new lengths to help us win the war on disease.

We know we cannot fight this fight alone – it is too big and too important. My parents understood that when they established an endowment to cover Van Andel Institute’s facility costs, operating expenses, and a large percentage of our research in perpetuity. Fully 100 percent of your donation goes directly to the research labs and science education classrooms where we’re shaping the future of disease treatment and therapies.

In these pages, I invite you to read some of my favorite stories of Institute advocates who have adopted our mission of research, discovery and hope and made it

their own. Some are complex initiatives brought about by corporations or established institutions. Others are simple but powerful efforts by gracious, everyday people who feel compelled to make a difference.

Every partner – every one of you – matters. Thank you for believing in us, and for partnering with us to provide hope to a world hungry for answers.

Warmly,

David Van Andel, Chairman and CEO

Discovery p.15

Fostering a love of science.We are lighting the way with new science education standards and fostering a love of science in students and teachers.

hope p.21

Collaborating across the globe. We are able to make progress faster and take our breakthroughs further by collaborating with partners across the globe.

Improving the lives of those living with disease.We are leading the charge to speed the transition of research from bench-to-bedside and make discoveries focused on improving the lives of those living with cancer and neurodegenerative diseases.

research p.5

Fully 100 percent of your donation goes directly to the research labs and science education classrooms where we’re shaping the future of disease treatment and therapies.

v a n a n d e l i n s t i t u t e 4

Changing the course of research, discovery and hope.

Every discovery in our laboratories is another

important step in our quest to improve the

health and enhance the lives of current and

future generations. Thanks to generous donors

like you, biomedical research at Van Andel

Institute is leading to innovative therapies and

treatments that will change the course

of human health.

Changing the course of research, discovery and hope.

V A N A N D e L r e S e A r C h I N S t I t u t e 6

Time, Treasure anD TalenT

George Sharpe Sr. is a self-made man. Growing up in Detroit, George understood the value of hard work and the importance of community. Starting as a car porter, he washed cars for a local dealership. His determination and sales ability served him well, and in 1982 he moved to West Michigan with his wife Linda, daughter Nicole and sons, Blair and George Jr., and purchased his first dealership. George’s two sons soon began working alongside their father, learning the business and the tools of the trade.

Blair and George Jr. now run a number of successful luxury car dealerships. “We learned early about the business and grew to love it,” said George Jr. “My dad made sure we knew what it meant to earn a dollar and the value of hard work,” said Blair.

When George Sr. was diagnosed with Parkinson’s disease, the brothers decided it was their responsibility, as businessmen and community leaders, to support research that would improve the lives of those living with the disease. Giving back and leveraging time, treasure and talent in the service of community is the Sharpe family credo.

“We believe in what we’re doing, and one of our corporate philosophies is that you are only as strong as your community,” said Blair. “Community and business are a symbiotic relationship.”

The Sharpe family has partnered with Van Andel Institute, collecting funds and chairing special events to benefit Parkinson’s disease research. The family was chosen by Van Andel Institute Board of Governors member Tony Asselta to chair the popular

Winterfest event that he led for more than eight years. “The Sharpes are dedicated individuals in the community and everything they do comes from the heart,” said Asselta. “Like the Sharpes, my father also had Parkinson’s, so I know how important it is to support Van Andel Institute’s research into this disease.” The Sharpes had the opportunity to meet researchers like Dr. Patrik Brundin, Head of the Laboratory of Translational Parkinson’s Disease Research at Van Andel Institute, who share their passion for what research can do to benefit the greater good. Blair believes that their family partnership with the Institute can have a lasting impact on the future of Parkinson’s disease.

“My father says, ‘We might not find a cure for Parkinson’s disease in my time, but hopefully my children and grandchildren won’t have to deal with this disease.’”

a personal connecTion

Parkinson’s disease affects more than 1 million people in the United States. The neurodegenerative disease impacts an individual’s motor functions, cognitive abilities and quality of life and often goes undetected until the physical symptoms become apparent in the patient. Currently, there is no cure for Parkinson’s disease.

“I saw my father battle Parkinson’s disease for 22 years, and I know how the disease can impact patients,” said Brundin. “I also know that Van Andel Institute is completely devoted to researching and solving the many issues presented by Parkinson’s disease, and we’re going to stay with it until we’re done.”

Your support of Van Andel Institute allows for extraordinary and quick advances in the treatment of Parkinson’s and neurodegenerative diseases. Every gift plays an important role in the goal to diagnose the disease earlier and discover treatments to slow disease progression and restore brain function, providing hope to patients and their families. Donate to the Center for Neurodegenerative Science to continue this exciting work at vai.org/give.

$800,000Van Andel Institute’s annual Winterfest event has raised $800,000 to benefit Parkinson’s disease research

c e n t e r f o r n e u r o d e g e n e r a t i v e s c i e n c e

G I V E T O D A Y A T V A I . O R G / G I V E7

key Discoveries

Parkinson’s Disease Treatment Van Andel Institute participates in the Linked Clinical

Trials initiative designed by The Cure Parkinson’s Trust

to identify new treatments for Parkinson’s disease

by repurposing medications approved to treat other

conditions. Repositioning drugs that have already passed

Phase I safety studies substantially cuts the time and

costs associated with traditional drug development and

brings new hope to people with Parkinson’s disease.

Slowing Parkinson’s Disease The discoveries by Van Andel Institute’s Center for

Neurodegenerative Science Director Dr. Patrik Brundin

and colleagues in Europe may lead to new therapies

that slow progression of Parkinson’s disease. For the

first time, the team showed that a misfolded protein

associated with Parkinson’s disease can travel from

neurons in the olfactory bulb – one of the areas first

impacted by the disease – to other regions of the brain.

center for neurodegenerative sc ience

“We believe in what we’re doing, and one of our corporate philosophies is that you are only as strong as your community. Community and business is a symbiotic relationship.”–Blair Sharpe

george sharpe Jr., dr. Patrik brundin and blair sharpe

c e n t e r f o r n e u r o d e g e n e r a t i v e s c i e n c e

v a n a n d e l r e s e a r c h i n s t i t u t e 8

“Because of our size, and the way we do things, we can ensure that all donors have a direct impact on the work we do here.”–Dr. Jeff MacKeigan

dr. Jeff macKeiganG I V E T O D A Y A T V A I . O R G / G I V E9

c e n t e r f o r c a n c e r a n d c e l l b i o l o g y

an unlikely Team

Dolly Konwinski and Dr. Jeff MacKeigan are an unlikely team. Dolly is retired and in her early 80s, and MacKeigan is Associate Professor and Head of the Laboratory of Systems Biology at Van Andel Institute, but together they are a powerful force in the fight against cancer.

In grade school, Dolly played sandlot baseball pick-up games with the boys in her West Side Chicago neighborhood, and at the age of 15, Dolly went on to play for the post-war Women’s League in the 1940s and 1950s. Being one of the first women in professional sports was difficult, but the experience strengthened her character and resolve.

This resolve was tested years later when her husband Bob was diagnosed with cancer. After her husband’s battle with cancer, surgery and recovery, Dolly became increasingly aware of the prevalence of cancer. One day while watching her beloved Detroit Tigers, Dolly noticed something that would set her on an unforeseen path.

“I sat down at the beginning of a game and one player has a pink bat, and another guy in the on-deck circle has a pink bat… and I thought I’d get some pink baseball bats and get champion athletes to sign them, then I’d sell them and give the money to cancer research,” said Konwinski.

Dolly decided to leverage her recognition as a ballplayer to collect more than 40 professional athletes’ signatures on four bright pink bats. Sports luminaries such as Jack Nicklaus, Gale Sayers and Pete Rose all signed Dolly’s bats. Dolly reached out to Dr. Jeff MacKeigan, Associate Professor and Head, Laboratory of Systems Biology, and told him of her plans. MacKeigan invited Dolly to the Institute for a tour

and was struck by her passionate support of the work he was doing. “She had that personality where she wanted to see directly where her funds were going,” MacKeigan said.

“She got to visit the laboratory and wanted to help us buy a piece of equipment or support an experiment… she emphatically wanted to help.”

After Dolly’s visit with MacKeigan, she committed to donate all of the funds from her pink bats to the Institute in support of cancer research. In Dolly’s words, her efforts were a “labor of love.”

small DonaTions, Big impacT

It has been said that there is no such thing as a small donation, and that is especially true at Van Andel Institute. Because of the generous

endowment left by founders Jay and Betty Van Andel, 100% of every donation goes directly into the labs. At the Institute, there is a direct, personal connection between donors and Institute researchers.

Gifts of any size have a significant role to play in forwarding Van Andel Institute’s mission. MacKeigan and his team began the TSC (tuberous sclerosis complex) Pathway of Hope initiative in 2013 that hopes to develop improved treatments for the rare tumor disorder. This initiative was funded by private donors as well as the Michigan Strategic Fund through the Michigan Economic Development Corporation.

“All funds, no matter how large or small, are going to an important experiment or piece of equipment that helps push our research forward,” MacKeigan said.

“Because of our size, and the way we do things, we can ensure that all donors have a direct impact on the work we do here.”

Your gift makes a difference in the work of Van Andel Institute scientists. Support Van Andel Research Institute by giving today at vai.org/give.

key Discoveries

Breast Cancer Van Andel Institute scientists have shown the

interaction between MET and HER2 (ERBB2+) receptors

(two important genes related to cancer) is linked to

tumors resistant to targeted therapies. The discovery and

understanding of this relationship not only shed light

on some of the mechanisms behind breast cancer but

also may aid in the development of novel treatments.

Anxiety, Depression and Migraines Van Andel Institute scientists, along with colleagues in

China, discovered the structural blueprint that will aid

in the design of more selective activators of serotonin

receptors. Serotonin is a neurotransmitter, and its

receptors are important drug targets for conditions

such as anxiety, depression and migraines.

OsteoarthritisResearch initiated in Van Andel Institute’s Center for

Cancer and Cell Biology and continued with colleagues

in the Center for Skeletal Disease and Tumor Metastasis

has linked a deficiency of Mig-6, a gene associated with

joint stability, to osteoarthritis development and the

regulation of cartilage cells. This work could lead to

disease-modifying treatments for osteoarthritis, which

is the most common form of joint disease in humans.

center for cancer and cell b iology

100%100% of any philanthropic contribution to Van Andel Institute goes directly to research, discovery and hope.

v a n a n d e l r e s e a r c h i n s t i t u t e 1 0

50%

50% of people with aneurysmal bone cysts

are children.

dr. matt steensma and nathaniel

G I V e t o D A Y A t V A I . o r G / G I V e1 1

coming TogeTher for naThaniel

Nathaniel is a spirited five-year-old who was referred to Dr. Matt Steensma, an Assistant Professor at Van Andel Institute’s Center for Skeletal Disease Research, who over-sees the Institute’s Laboratory of Musculoskeletal Oncology. Steensma is also an orthopedic oncological surgeon with Spectrum Health Medical Group who practices at Helen DeVos Children’s Hospital and maintains a position at Michigan State University College of Human Medicine. Following an MRI and biopsy, Steensma discovered Nathaniel had an aneurysmal bone cyst – an aggressive, bone-eating tumor. Although not cancerous, the tumor was damaging bone, causing pain and making it difficult for Nathaniel to walk. Because of the tumor’s location, surgery was not an option.

“This was one of the most severe cases of an aneurysmal bone cyst in a child,” Steensma said. “When these tumors occur on the spine, they can be very difficult to treat because of the anatomy that’s around them.”

Steensma scoured literature trying to find an effective treatment and discovered an FDA approved treatment for a related tumor. This therapy targets a protein called RANK ligand (RANKL), and he found significant evidence that aneurysmal bone cysts also contain the protein RANKL. He decided repurposing this therapy might benefit his patient.

With oversight by Dr. Deanna Mitchell, a pediatric oncologist at Helen DeVos Children’s Hospital, Nathaniel was placed on a monthly regimen that entailed a simple injection beneath the skin. In two months, his pain was almost completely gone, and he was able to walk without difficulty.

“Nathaniel has had a dramatic response with this drug, and it’s been sustained more than a year with minimal side effects,” Steensma said. “We are delighted. It was a much better treatment than surgery.”

In order to determine if this therapy would benefit other patients with similar tumors, Steensma had to return to his lab at Van Andel Institute.

“I was able to look at VAI’s banked samples of aneurysmal bone cysts and demonstrate that RANKL is expressed highly in these specific tumors, which suggests that other bone cysts like Nathaniel’s can be treated similarly,” Steensma said.

Steensma is proud that his clinical team at Helen DeVos Children’s Hospital and the research team at Van Andel Institute played a significant role in changing Nathaniel’s life, with the potential to benefit others around the world.

a shareD purpose

A collaborative research environment, such as the one found at Van Andel Institute, accelerates the speed at which discoveries can benefit patients. This focus allows researchers and clinicians to work in bold, innovative ways.

Van Andel Institute researchers have the potential to impact more patients around the world with your help. Your gift significantly aids the fight against disease by funding special projects and purchasing state-of-the-art equipment to help individuals like Nathaniel. Every donation speeds the rate scientists are able to put innovative new treatments into patients’ hands. Support the innovative work at Van Andel Research Institute by giving today at vai.org/give.

“It’s incredibly engaging and stimulating work,” Steensma said. “I can see firsthand our clinical research results, and that’s really what I love about my job.”

center for sKeletal d isease and tumor metastasis

Van Andel Institute researchers like Dr. Matt Steensma have the potential to impact more patients around the world with your help.

c e n t e r f o r s K e l e t a l d i s e a s e a n d t u m o r m e t a s t a s i s

key Discoveries

Prostate Cancer Van Andel Institute scientists are working to further

understand a key signaling pathway that may provide

more effective treatments for patients whose prostate

cancer has spread to their bones. Currently, there is

no curative treatment and few dependable palliative

options once the cancer moves to the skeleton.

Osteoarthritis Scientists in Van Andel Institute’s Center for Skeletal

Disease and Tumor Metastasis have shown that

a mutation of the Lrp6 gene can lead to severe

osteoarthritis and further clarifies the roles of the Lrp6

and Lrp5 genes in bone stability. By using a genetic

model, Van Andel Institute scientists were able to

ascertain a clear link between the genes and the cells

responsible for the formation of bone.

Osteoarthritis Research initiated in Van Andel Institute’s Center for

Cancer and Cell Biology and continued with colleagues

in the Center for Skeletal Disease and Tumor Metastasis

has linked a deficiency of Mig-6, a gene associated with

joint stability, to osteoarthritis development and the

regulation of cartilage cells. This work could lead to

disease-modifying treatments for osteoarthritis, which

is the most common form of joint disease in humans.

v a n a n d e l r e s e a r c h i n s t i t u t e 1 2

rewarDing research

Focusing on the patient is an everyday reality for Dr. Lena Brundin, Associate Professor in Van Andel Research Institute’s Center for Translational Medicine and Associate Professor at Michigan State University College of Human Medicine. Dr. Brundin was a practicing clinical psychiatrist in Sweden for almost 10 years, and this direct clinical work with patients inspired her to search for answers regarding mental health in her laboratory at Van Andel Institute.

“It’s an extremely rewarding way of working,” said Brundin. “I think it’s really fundamental to start with patients and build on that in the laboratory in order to have progress in science and develop good treatments.”

Brundin, who focuses on depression and suicidality, uses basic research and clinical practice to develop new therapies for psychiatric patients with a focus on depression and suicidality. She collects data from patients and uses that information to conduct tests in her Van Andel Institute laboratory in collaboration with Spectrum Health and Pine Rest Christian Mental Health Services.

Her team made exciting discoveries in 2013 that may lead to more effective treatments for patients living with severe mental health issues. Brundin also engaged in a study measuring inflammatory markers in cerebrospinal fluid, the fluid that surrounds the brain and spinal cord, of patients with Parkinson’s disease. The study found a significant association between inflammation and non-motor symptoms of Parkinson’s disease such as fatigue, depression and anxiety, which dramatically affect a patient’s quality of life.

“If inflammation is really the cause of some severe psychiatric symptoms, there are plenty of anti-inflammatory medications that are already approved for clinical use. We’re a couple steps ahead compared to inventing something completely new,” said Brundin.

Repurposing drugs that have already been approved by the FDA is a practice common in translational medicine that gives patients access to new, more effective treatments faster than developing new therapies. More than 14.8 million adults are affected by depression in the United States,

and the need for improved treatments has never been greater. Brundin’s collaborative research is at the forefront of translational medicine, and her focus remains on how discoveries can benefit patients.

“We’re trying hard to find new treatments against

depression,” said Brundin. “We are excited about the progress we are making so far.”

perfecT parTners

Creating affiliations with research institutions and universities has been a core value of Van Andel Institute since its inception. So when Michigan State University built its College of Human Medicine in Grand Rapids, collaboration was a priority.

Donor partnerships are just as important as institutional partnerships. Working with you, researchers like Brundin are able to acquire state-of-the-art equipment, support additional staff and conduct promising projects. Your support is crucial to their success. Give today at vai.org/give.

“We’re trying hard to find new treatments against depression. We are excited about the progress we’re making so far.” –Dr. Lena Brundin

c e n t e r f o r t r a n s l a t i o n a l m e d i c i n e

With your help, translational medicine gives patients access to new, more effective treatments faster than developing new therapies. 14.8

millionMore than 14.8 million adults

are affected by depression in

the United States.

G I V E T O D A Y A T V A I . O R G / G I V E1 3

key Discoveries

Exciting discoveries in translational medicine, made possible through institutional collaborations, may provide more effective treatments for millions of mental health patients.

Malignant Melanoma Using melanoma-based avatar models that mirror

human tumor progression, Van Andel Institute scientists

identified several acquired drug resistance mechanisms

for targeted cancer therapies. The group also identified

a combination drug approach that led to sustained

remissions in a validated pre-clinical system.

Pancreatic Cancer Van Andel Institute scientists have developed a new

method that will aid in the diagnosis of precancerous

cysts in the pancreas, which can develop into an

aggressive form of cancer. In two studies, the new

method demonstrated 93% and 91% accuracy, making

the test more reliable than current diagnostic methods.

Pancreatic cancer is the fourth leading cause of cancer

death in the U.S. and can spread quickly, making early

diagnosis vital for treatment.

center for translational medic ine

dr. lena brundin v a n a n d e l r e s e a r c h i n s t i t u t e 1 4

Changing the course of research, discovery and hope.

Changing the course of research, discovery and hope.

A young student inspired by scientific

inquiry today has the potential to become a

groundbreaking research scientist tomorrow.

With your support, Van Andel Education

Institute is reimagining the power of science

education, igniting excitement among young

people, and helping teachers learn to light

the fire of discovery.

V A N A N D e L e D u C A t I o N I N S t I t u t e 1 6

Jason dunn and brookeG I V e t o D A Y A t V A I . o r G / G I V e1 7

“Science is really fun in his class because you get to do a lot of different experiments. At first I thought I wouldn’t like science, but now it’s fun!”

In a world where science and technology are pushing innovation at an exponential rate, children are part of the next generation of students who need critical thinking and problem-solving skills to succeed. Teachers who are using the teaching model created by Van Andel Education Institute’s Science Academy develop their students’ practical science skills and knowledge at an early age.

eXpanDing influence

The Science Academy is changing the lives of every teacher and student it touches and is thrilled at the success of its programs. But there’s more to be done. Plans include expanding middle and high school student and professional development programming, but additional resources are required to make that vision a reality.

Van Andel Education Institute depends on your support to help teach more teachers and students to engage with

science in new ways. Your gift expands program access, acquires new equipment and inspires students who might become the scientists to make the discoveries that change the course of cancer and disease treatment. Change the life of a student today at vai.org/give.

milesTones

14 Van Andel Education Institute’s inquiry-

based instructional process QPOE2®

(Question, Prediction, Observation, Evaluation,

Explanation) impacted 14 school districts

and three intermediate school districts.

500+ More than 500 teachers were trained

in Van Andel Education Institute’s

QPOE2® instructional process.

500+ More than 500 students attended

Van Andel Education Institute’s

Science Academy.

Van Andel Education Institute depends on your

support to help students, like Brooke, engage in

science in new ways.

“The Science Academy’s goal is to get students to think and act like scientists.”–Jason Dunn

“I thought science was just reading books and writing stuff down on paper…at first I thought I wouldn’t like science, but now it’s fun!”–Brooke

science academy

innovaTion in The cl assrooms

When Jason Dunn, a fifth-grade teacher, first became involved with Van Andel Education Institute five years ago, he had no idea just how much it would influence his career and his classroom. Dunn, along with other West Michigan teachers, was invited to the Science Academy to hear about the program’s mission and learn how educators can play an instrumental role in inquiry-based science education, a model that encourages critical thinking, problem solving and collaboration.

“The Science Academy’s goal is to get students to think and act like scientists, and through this process you actually see them applying those skills, as opposed to other students who skim a textbook in search of an answer,” said Dunn.

Having successfully completed the three-year training program, Dunn now implements the model on a daily basis. Much like the work conducted by biomedical researchers at Van Andel Research Institute, the students in Dunn’s class address questions through a number of investigations that allow them to ask scientific questions, hypothesize answers and make their own discoveries.

Student Brooke is living proof. “I thought science was just reading books and writing stuff down on paper,” said Brooke, one of Dunn’s current fifth-grade students.

s c i e n c e a c a d e m y

v a n a n d e l e d u c a t i o n i n s t i t u t e 1 8

a scienTisT of Tomorrow in The making

When Eric Nollet attended the annual West Michigan Regional Undergraduate Science Research Conference at Van Andel Institute, he was delighted to find a number of college students who shared his recently discovered passion for medical research. He listened to presentations and discussed findings with a number of peers throughout the day, but for Nollet, the most important presentation didn’t come until the end of the conference. It was a presentation that would fundamentally change the course of Nollet’s life.

Dr. Nick Duesbery, Associate Professor, Center for Cancer and Cell Biology, Head, Laboratory of Cancer and Developmental Cell Biology, spoke about using basic research to develop and test a type of protein-based drug that could kill blood vessels in a specific type of tumor. Although Duesbery did not think his presentation would alter someone’s life path, what he said that day had a profound impact on Nollet’s future.

“It was really inspiring to see someone who was doing basic research suddenly translate that to medicine,” said Nollet. “This presentation helped me realize how important basic research really was to discovering new types of treatments or therapies.” Nollet was overjoyed in 2010 when he was accepted into the exclusive Van Andel Institute Graduate School. “I loved the small class size,” says Nollet. “It’s more hands-on, and the lessons are driven by what you need to know.”

Van Andel Institute Graduate School teaches students how to conduct themselves in research laboratories with a focus on discussion and hands-on training led by world-renowned researchers in classes containing a maximum of four students. When students aren’t studying, they can be found in the research labs working alongside their mentors and peers.

Nollet has spent his time working in the lab run by Dr. Cindy Miranti, Associate Professor, Center for Cancer and Cell Biology, Head, Laboratory of Integrin Signaling and Tumorigenesis, for nearly four years, working on a single project revolving around prostate cancer that is resistant to standard treatment.

“I’m more of a critical thinker now because of the way classes are conducted, and we are held accountable for our work just like the researchers are. Although I look forward to continuing my career, it will be difficult to leave. I like it here,” said Nollet, reflecting on the past three years.

parTnerships for The fuTure

Van Andel Institute Graduate School believes in the power of partnerships, which is why the school works with a number of universities to host an annual research conference for undergraduate students.

“A critical mission for Van Andel Institute is to help develop the scientists of the future,” said Dr. Steven Triezenberg, Director of Van Andel Education Institute, and President and Dean of Van Andel Institute Graduate School. “We want to encourage students of all ages to pursue fulfilling science careers.”

When you support Van Andel Institute Graduate School, you provide students an invaluable learning opportunity. Your gift covers travel grants, professional development and fellowships that facilitate the transition from graduate student to professional scientist. You can ensure students receive the necessary training to become scientific leaders of tomorrow by giving at vai.org/give.

“ It was really inspiring to see someone who was doing basic research suddenly translate that into medicine.”–Eric Nollet

v a n a n d e l i n s t i t u t e g r a d u a t e s c h o o l

G I V E T O D A Y A T V A I . O R G / G I V E1 9

milesTones

graduate school

224 4 graduates to date

22 graduate students

1:1 student-faculty ratio

“ A critical mission for Van Andel Institute is to help develop the scientists of the future.” –Dr. Steven Triezenberg

eric nollet and dr. cindy miranti

v a n a n d e l i n s t i t u t e g r a d u a t e s c h o o l

You make a difference in the future of scientific research when you support the students attending Van Andel Institute Graduate School.

Accredited by North Central Association’s Higher Learning Commission

v a n a n d e l e d u c a t i o n i n s t i t u t e 2 0

Changing the course of research, discovery and hope.

Changing the course of research, discovery and hope.

V A N A N D e L I N S t I t u t e 2 2

®

A community that cares is filled with the

power to make an impact. Van Andel

Institute is supported by a diverse group

of committed people and organizations

connected by a shared passion to advance

research, discovery and hope. Thank you for

joining us in the fight against cancer and

neurodegenerative diseases.

40,000 sTeps, $40,000 raiseD To fighT cancer

When a family member of an eighth-grade student at Duncan Lake Middle School was diagnosed with cancer in 2009, she presented the idea for a cancer walk – and the entire school

rallied behind her. The school decided to support cancer research at Van Andel Institute because of its 100% Hope® promise.

“We know that 100% of what we raise goes to research,” said Ryan Graham, Principal at Duncan Lake Middle School. “For our students, seeing items in the lab that Duncan Lake helped purchase and hearing

a researcher talk about his work is powerful.”

Duncan Lake’s Cancer Walk was planned by a leadership team of six students and implemented by an army of 60 student council volunteers. The entire school participated in a fundraising competition for six weeks leading up to the event, and the students managed all the fundraising activities. The students held bake sales, raffled off five-pound gummy bears and sold tickets to throw wet sponges at teachers.

The school currently has three students battling cancer, and most students have been touched by the disease through a friend or family member. “My grandpa had cancer,” explained eighth-grade organizer Jason Blunt. “Knowing that there are people who are working hard to try to cure cancer makes me feel good.”

For these students, fighting cancer is an expression of their support for cancer research and the joyful feeling of school spirit. “We take joy in fighting cancer; celebrate with us!” said Graham.

The power of purple

Purple Community, Van Andel Institute’s grassroots fundraising program, connects individuals who want to make a difference with the resources needed for action. Working together, individuals, businesses, schools and communities have the ability to influence the future of human health.

Duncan Lake Middle School students have changed the course of research at Van Andel Institute by raising more than $40,000, supporting the research of Dr. Nate Lanning, Postdoctoral Fellow in the Lab of Systems Biology.

One focus of Lanning’s research is to understand the metabolism of glioblastoma multiforme (GBM), the most common and aggressive malignant primary brain tumor found in humans. Thanks to the donations from Duncan Lake Middle School, a new piece of equipment was purchased in 2013. This equipment allows him to take more accurate measurements in his experiments and provides critical insights into the metabolism of GBM.

“I cannot tell you how fast the equipment has accelerated my research,” said Lanning. “It has supported not only my research but also the work of others researching breast cancer, melanoma and more at Van Andel Institute.”

$40,000Funds raised by Duncan Lake Middle School students to purchase new lab equipment:

100%100% of every gift to Van Andel Institute goes directly to the laboratories and classrooms.

P u r P l e c o m m u n i t y ®

G I V E T O D A Y A T V A I . O R G / G I V E2 3

200+ More than 200 students and community members attended the inaugural Purple Community Leadership Academy.

$900,000

More than $900,000 has been raised for cancer and neurodegenerative disease research since 2009.

302,595

More than 300,000 people have participated in Purple Community events since 2009.

255

Purple Community has hosted 255 events since 2009.

“Knowing that there are people who are working hard to try to cure cancer makes me feel good.”–Jason Blunt

PurPle community

Willie Weninger, dr. nate lanning, Joelle henry, Jason blunt, trenton beemer, Joey shuster, ryan graham, liz alexander and callie delaney

milesTones

v a n a n d e l i n s t i t u t e 2 4

a Tale of Two ciTies

More than 1.6 million people are diagnosed with cancer in the United States each year, but for those living with cancer, hope knows no geographical boundaries. The need for improved treatments and diagnostics is shared by everyone affected by this devastating illness. The goal of any cancer awareness campaign is to give a feeling of connectivity and community to patients, caregivers and their families. The campaign can also highlight those who are working to better understand cancer and develop improved therapies.

When Van Andel Institute partnered with the Detroit Red Wings to bring about Hockey Fights Cancer Night, a powerful message of hope was sent across the state. The event involved more than 20,000 people in support of cancer and disease research at Van Andel Institute and earned more than four million impressions. The famed Joe Louis Arena was enveloped with purple rally towels and Purple Community signage. Fans in attendance also had the opportunity to participate in awareness initiatives in remembrance of friends or loved ones who had been affected by cancer.

This night gave hope not only to the thousands of people at the game but also to the millions watching in the far-flung neighborhoods of Motor City, towns in Michigan and regions across the United States. This night let people know that when it comes to fighting cancer, Van Andel Institute and the Red Wings believe in the power of community, no matter where you call home. Tom Wilson, President and CEO of Olympia Entertainment, the organization in charge of all Red Wings operations, feels this connection to community is inherent in the Red Wings’ philosophy.

“Connecting with the community has always been a high priority for the Red Wings, especially when it comes to battling cancer and disease,” said Wilson. “We are honored to be able to team up with Van Andel Institute, a leader in biomedical research and education, and Purple Community

is a great way to engage our fans and raise funds for an outstanding cause.”

This idea of community connection is woven throughout Van Andel Institute’s philosophy of engagement, and each year organizations like the Detroit Red Wings decide to partner with the Institute and Purple Community to proactively support dynamic biomedical research and empower their communities in the fight against cancer and disease.

Business fighTs cancer

Purple Community partners with businesses and organizations, like the Detroit Red Wings, to increase awareness and funding for cancer and disease research and science education at Van Andel Institute. In addition to hosting company events, businesses support Purple Community through special products and offers.

Purple Community currently has twelve corporate cause marketing partners and is regularly adding new ones. Restaurants like Brann’s Steakhouse and Grill donate a percentage of sales to Purple Community; Lake Michigan Credit Union sells purple tribute badges in its branch locations; and AOL promotes Van Andel Institute on its homepage to help spread its mission.

Thanks to corporate partners like you, Purple Community is amplifying its message of hope across the country.

20,000+Hockey Fights Cancer Night involved more than 20,000 people to support cancer and disease research at Van Andel Institute.

P u r P l e c o m m u n i t y ®

G I V E T O D A Y A T V A I . O R G / G I V E2 5

Purple community members and detroit red Wings defenseman Jakub Kindl

evenTs

Purple Community members host a variety of events to support Van Andel Institute: from children’s lemonade stands to corporate jeans days to school sporting events and everything in between.

Corporations, businesses and organizations can also join Purple Community through cause marketing partnerships. Current Purple Community cause marketing partnerships include:

Great Lakes Scrip Grand Rapids Griffins

Brann’s Steakhouse West Michigan and Grille Whitecaps

AOL

For more information on how you and your organization can join Purple Community, visit purplecommunity.org

PurPle community

v a n a n d e l i n s t i t u t e 2 6

“It’s great to have such strong support for the Institute’s mission, and every year we ask ourselves, ‘How can we make this event better? How can we make a greater impact?’”–Rebecca Wierda

$557,000+Since 2006, Couture for a Cure has raised more than $557,000.

rebecca WierdaG I V E T O D A Y A T V A I . O R G / G I V E2 7

a runway To Discovery

Rebecca Wierda is an entrepreneurial fashionista, a woman with strong business acumen, drive and a passion for fine women’s clothing. When she took ownership of Leigh’s, a women’s specialty store and a 30-year-old retail institution in Grand Rapids, she didn’t just fill the racks; she built a new store. Today, Leigh’s is a thriving small business and one of the few locations in West Michigan where women can purchase high-end designer collections.

For eight years, Wierda and her team have been partnering with Van Andel Institute to organize Couture for a Cure, a fundraising event benefiting the Institute’s research and education initiatives. The event, first conceived by Carol Van Andel and Wierda, started small with only a few dozen guests gathering at Leigh’s. The event has since grown to host more than 500 guests at Van Andel Institute and has raised hundreds of thousands of dollars for the Institute’s programs.

“It’s a great showcase for the work being done at Van Andel Institute and a great opportunity for my business to partner with the Institute in support of cancer and disease research as well as science education,” said Wierda.

The dynamic businesswoman is proud that Leigh’s can play a role in supporting life-changing cancer and disease research.

“My husband lost his father to cancer and my mother is a cancer survivor, so I think it’s really special that we have this world-class research institute in our community and I love that we can bring this important work into focus,” said Wierda.

“I love that we can bring this important work into focus.”

– Rebecca Wierda

signature sPecial events

Wierda views Couture for a Cure as an event on par with New York’s famed Fashion Week and has made a point of bringing top designers to Van Andel Institute to showcase their seasonal collections.

“After doing the event for so many years, we now have designers coming to us and asking to be part of it,” said Wierda. “It’s great to have such strong support for the Institute’s mission, and every year we ask ourselves, ‘How can we make this event better. How can we make a greater impact?’”

a communiTy of evenTs

Couture for a Cure was one of more than 50 signature special events hosted by Van Andel Institute in 2013. Signature special events invite people to develop a connection with the Institute and become active participants in its mission.

Events are an important aspect of Van Andel Institute’s fundraising and community engagement strategy, and they create lasting philanthropic partnerships, as well as provide critical funds for the Institute’s biomedical research and education initiatives.

van anDel insTiTuTe naTional iniTiaTive

David and Carol Van Andel, as well as representatives from the Institute, hosted events in cities across the United States with the aim of bringing forth the mission of research, discovery and hope. These events, built on the foundation of community-minded philanthropists and business leaders, helped usher in a new era of nationwide exposure for the Institute.

s i g n a t u r e s P e c i a l e v e n t s

2 8 v a n a n d e l i n s t i t u t e

51Total Events

191 EventSponsorsDonors engaged through special events

Where events took place

2013

3,000+ Holland, MI | Grand Rapids, MI | Troy, MI | Chicago, ILNew York, NY | Menlo Park, CA | Santa Barbara, CA

Compared to 44 events in 2012

VAINIPhilanthropic PartnershipsVan Andel Institute National Initiative's cross-country events created new philanthropic partnerships, increasing awareness of the Institute's mission.

4.26.13

The inaugural Carol Van Andel Angel of Excellence Award honors those individuals who have made a significant contribution toward promoting and enhancing the brand and image of Van Andel Institute through volunteer service and commitment.

G I V E T O D A Y A T V A I . O R G / G I V E2 9

signature sPecial events

carol van andel at couture for a cure 3 0 V A N A N D e L I N S t I t u t e

Because of your generosity, we are accelerating our research and finding innovative ways to translate our laboratory results into patient treatment options faster and more efficiently. Every day in laboratories and classrooms, we see your support making an incredible difference. Thank you for partnering with us.

van anDel insTiTuTe founDers

Jay and Betty Van AndelJohn H. and Nancy L. BattsPeter C. and Pat CookRichard and Helen DeVosRalph and Grace HauensteinSidney and Joanne JansmaFred and Lena Meijer

$500+ Donors

Dave and LeeAnn Abel Acrisure, LLC Ada Attic Self Storage Ada Christian School Nick and Shellie Adamy

Marguerite Aitken Samara Albury Alfresco Landscapes Martin and Sue Allen Attallah and Marie Amash *American Border Collie

Association, Inc. *Amicus Management Jeffrey and Tammy Ammon Amway **Amway Grand Plaza Hotel **Aon Aquinas College *Dr. Dorothy Ciner Armstrong Richard and Patti Ashack Tony and Kathleen Asselta *Audio Advisor, Inc. Avalon Building Concepts Sandra Badini Bill and Sue Baer James and Shirley Balk *Bank of America Merrill Lynch *The Bank of Holland Bar Divani *Barnes & Thornburg LLP Jean Bassett William and Debra Battjes John and Nancy Batts **Dwane and Joyce Baumgardner David Baumgartner and

Patty Norman Jeff and Cathy Bayer

BBG Corporation BDO USA, LLP *Jean Behnke Belwith Products, LLC William and Amy Bennett Berends Hendricks Stuit

Insurance Agency Inc. Scott and Natalie Bernecker William and Sandra Berry Gregory and Rajene Betz *Kenneth and Judy Betz *Betz Industries *David and Jill Bielema Richard and Marcia Bishop *Blue Cross Blue Shield of

Michigan Foundation *Bluewater Technologies *Chuck and Christine Boelkins *Sharon Bogerd Booth-Hilaski Insurance Mary Kay Borisch Bouwkamp Masonry James and Florence Bouwman Grace Bouwman Bradford Company Patrick and Kristine Brady Brann’s Steakhouse and

Sports Grille Alex and Michelle Bratton James Briles The Brooks Family *Richard Brown

Wayne and Theresa Brown Bruce Heys Builders, Inc. James and Ellen Bruinsma Patrik and Lena Brundin Laurie Buettner The Buffett Early Childhood

Fund Buist Electric *James and Martha Bultman The Bunbury Company John H. Busch Carol L. Bylsma *Byron Center Public Schools Calamos Advisors Caledonia Athletic Boosters Jerry and Suzanne Callahan *Calvin College Camp Canine, Inc. Lis Campbell Scott and Heidi Campbell Cancer & Hematology Centers

of Western MI, PC Cancer Prevention

Pharmaceuticals, Inc. John and Marie Canepa **The Family of Carl VanderZee, Sr. Carnevale *Josh and Linda Jo Carron Cascade Rental Center CAZZ Consulting The Center for Physical

Rehabilitation

Century Floor Space Arnie Chance The Chop House *Scott and Sarah Christopher Scott Christopher Homes *Thomas and Maryann Ciccarelli CityVū Bistro CitySēn Lounge Coins for Cole Coldbrook Insurance Group Colliers International *Love and Valeda Collins *The Color Run Steven and Diane Colvin Comerica Bank *Compass Group USA -

Eurest Dining Services *William Conely Peter C. and Emajean

Cook Foundation Cook Holdings Marty and Barbara Coon Cornerstone University *Kiki Courtelis Louise Courtelis Covenant Christian High School Roberta Cramer Bill and Marilyn Crawford Crowe Horwath LLP *The Crown Jewel Spa & Salon Deborah Crum Mimi Cummings

The Currie Foundation *Custer Workplace Interiors *Todd and Dawn Cutler Cynthia Rose Czech Holdings, LLC Davenport University *Jim and Joy DeBoer *Douglas DeCamp Douglas and Sandra Dekock *Deloitte *Elaine Demopoulos Dempsey Ventures, LLC Kevin and Nancy Denhof Detroit Red Wings Robert and Carol DeVilbiss The Daniel and Pamella DeVos

Foundation **The Dick and Betsy DeVos

Foundation **The Douglas and Maria DeVos

Foundation **The Richard and Helen DeVos

Foundation **Dickinson Wright PLLC *Diplomat Specialty Pharmacy Jeffrey and Mary Dixon DK Security *Downers Grove Junior

Woman’s Club Michael Drake Eileen Droscha Patrick and Leslie Drueke

Donors

G I V E T O D A Y A T V A I . O R G / G I V E3 1

Dubric Nick and Susan Duesbery Duncan Lake Middle School *Dykehouse Photography The John Dykema and

Michele Maly-Dykema Family Foundation *

Michael and Mary Dykema Thomas and Lois Dykstra Jeffrey and Monique Eardley East End Plumbing East Grand Rapids

Public Schools East Kentwood High School Jeremy Eaton Eenhoorn, LLC *Eikenhout, Inc. Ellis Parking Company Dr. Kathleen Ellsworth Mark and Anne Elve David and Pamela Emenheiser Encompass Steven and Karen Ender Barbara Erhards Erhardt Construction *Ernst & Young LLP *Marianne Evans Expression Rings of Hope Jim and Gail Fahner Mathew and Jennifer

Fahrenkrug Fairly Painless Advertising

Ferris Coffee & Nut Co.*Fidelity Charitable Gift Fund Fifth Third Bank **First Giving Paul and Charlene Fitzpatrick Flounder and Marty’s Putt Putt

for Purple Walter Fohlbrook John and Melynda Folkert *Margaret Fondren Andrew and Stacey Ford Forest Hills Pediatric

Associates PC Forest Hills Central High School **Forest Hills Northern High School *Forest Hills Public Schools *Foster Swift Bo and Jenn Fowler Bart Franklin David and Judy Frey Friends of Will Cancer

Foundation **Dan and Lou Ann Gaydou *Gazelle Sports Generation Care, PLC Genesis Publisher Services Gerrit’s Appliance Mark and Barbara Gerson Robert and Paula Geyer *Gene and Tubie Gilmore *The Gilmore Collection *Glass Concepts Incorporated

The Good Earth Cafe John and Nancy Gordon *GR Outdoor *Grand Haven Area

Public Schools Grand Rapids African American

Health Institute Grand Rapids Christian

Schools *Grand Rapids Community

College The Grand Rapids Community

Foundation *Grand Rapids Griffins *Grand Valley State University *Nancy Grandys-Jones Gary and Pam Granger Great Lakes Granite Works Great Lakes Paving Great Lakes Scrip Center *Charles and Julie Greenen Martin and Peggy Greydanus *Jefra Groendyk Group One Marketing Inc. Chandra Gruber GUTS Branding The H.T. Hackney Co. Stephen Haarman David and Gloria Haebich Dr. Jana Hall *Jeffrey and Christine Halvorson John and June Hamersma

Thomas Hammer Phyllis Hammond Fred L. Hansen Corporation *Hansen-Balk Steel Treating Co. Art and Betsy Hasse Hastings Manufacturing

Company, LLC *Ralph Hauenstein **Haworth Inc. Steve and Brenda Heacock *Clayton and Cheri Heathcock Hedke Painting Hedrick Associates Ted and Amy Heilman Linda Hellinge Daniel M. Helmholdt Thomas and Mary Helmstetter Mark and Valerie Henderson Teresa Hendricks-Smitley Robert Hensley Herman Miller Foundation *Robert and Barbara Herr John and Gwen Hibbard *Dan and Diane Hickey Philip and Sharon Hoekstra *Dirk and Victoria Hoffius *Matt and Laura Holman Earl and Donnalee Holton *Mark Holtvluwer and Wendy

Parr Holtvluwer Homewatch CareGivers

of West Michigan

David and Debra Hoogendoorn Hope College *Howard Miller Company **Matthew and Sarah Hudson Hudsonville Public Schools J.C. Huizenga *Humana William and Sue Hunt The Allen and Helen Hunting

Family Foundation *Ralph and Melissa Iannelli Ice Sculptures, Ltd. *Bea Idema *Ilitch Charities The ICN Foundation *José and Sue Infante Ingredion Inc. Win and Kyle Irwin *J&H Oil Michael and Sue Jandernoa **Mike Janowiecki Sid and Sharin Jansma *Jessie’s Ride for a Cure Charles and Carole Johnson Johnson Technology, Inc. JRM Holdings Joseph and Elizabeth Junewick Jim and Ginger Jurries *JVA Partners Paul and Linda Kalkman Andrew and Christina Keller John and Nancy Kennedy **

sources of funDing for research anD eDucaTion

* Leadership Society recognizes donors who have given more than $10,000 to the Institute. ** Legacy Society recognizes donors who have given more than $100,000 to the Institute.

4% Private Philanthropy

14% Grant & Contract Revenue (Direct)

82%

Endowment Income

3 2 v a n a n d e l i n s t i t u t e

Kenowa Hills Public Schools Kentwood Public Schools Kerkstra Family Charitable

Foundation Kerkstra Precast, Inc. William B. Kessel Craig and Debra Kinney *Birgit Klohs and Greg Northrup Donald Klopcic *Lawrence and Anne Kloth *Steven and Mary Joe Klotz Diane Kniowski Nathan and Nancy Kooienga Al and Robin Koop Blake and Mary Krueger Bryon and Leanna Krukowski James and Karen LaFleur Lake Michigan Credit Union *Lambert, Edwards &

Associates, Inc. Peter and Laurie Lamberts Ray and Jeannine Lanning Kenneth Larm Laura Mercier Law Weathers Edward and Jennifer Lazowski Olivier and Nathalie Leclercq Lee High School John M. and Mary Leese Leigh’s *Lennon Media Management Leo’s *

Lever Interactive Lighthouse Insurance Group Inc. Michael Litaker Little Caesar’s Pizza John and Pat Littleton Ray Loeschner*Tim and Kimberly Long *Lord, Abbett, & Co. LLC *Lorin Industries Nathaniel and Marcia Love Jane Lovell Lowell/Caledonia/South

Christian Hockey Team *Gary and Vicky Ludema *William and Lynda Luke Lundbeck LLC Michael and Suzanne Lunn William and Amy Mackay Jeffrey and Shannon MacKeigan John and Suzanne MacKeigan Mager Scientific Donald and Kathleen Maine Arthur Male Mancino’s of Greenville Mari J. Meyer Pancreatic

Cancer Trail Run for Hope *Paul and Deborah Marshall Kevin and Lisa McCaffrey Pat and Shirley McCleer Paul McCollum MD Sass Rick and Kathy Mead

Carmen Medina Medtronic, Inc. Mark and Mary Beth Meijer **Meijer *The Meijer Foundation **Karsten and Susanne Melcher Mercantile Bank of Michigan Merrill Lynch *Merrill Lynch - The Veldheer,

Long, Mackay & Bernecker Group **

Metro Health *Michelle Michael Michigan Pain Consultants Michigan State University -

College of Human Medicine *R. George Mickel Miedema Asset Management

Group Mika, Meyers, Beckett & Jones,

PLC Mike the Barber Classic *Milan’s Miracle Fund *Miles for Hope, Inc. Betty R. Miller Eric Miller Lee and Paulette Miller Jack H. Miller Howard J. “Buzz” Miller *Miller Industrial Gases LLC Albert Mitchell MLive Media Group

Modern Day Floral Michael and JoAnn Mooney Louis and Nancy Moran Morgan Stanley Smith Barney

Global Impact Funding Trust, Inc. Richard and Margaret Moritz Michael and Rachel Mraz Larry and Karen Mulder

Foundation Maribeth Mulvey Michael and Martha Munchhof Mark and Elizabeth Murray *Tim and Denise Myers National Football League

Refereees Association Neurofibromatosis Michigan *Nextwork Group, LLC Jim and Christine Nicolette Eleanore Nicolette Nobel Concrete, Inc. Norris, Perné and French LLP *North American Machine &

Engineering Co. Northern Trust O’Briens Market Deli ODL, Inc. *Juan and Mary Olivarez *Olympia Entertainment One Trick Pony ORG - West Michigan LLC Orthopedic Associates of

Michigan

Frank Padron Ana Paolo Papa K’s of Ada Tonya Parker Parkinson’s Disease Foundation James and Linda Payne *Robert Pearson and Karen

Kamerschen Thomas and Christine Pfennig Brian Picardat Timothy and Pamela Pietryga Pinewood Middle School Pioneer Construction *Lewis Pitsch and Teresa

Hendricks-Pitsch *Pitsch Companies Plante & Moran, PLLC *Brock and Plumb PNC Bank *Roberta Porter Jill Postma Powell Relocation Group PowerStrength Training

Systems Preusser Jewelers *Edgar and Elsa Prince

Foundation *Progress Chemical, Inc. Pure Barre Grand Rapids Putt for Parkinson’s Golf Outing Quality Air Service, Inc. Ranger Lacrosse Club

Raymond James Charitable Endowment Fund

The Red Geranium Cafe Reeths Puffer Schools *Regal Financial Group LLC Rescom Electric Inc. Margaret Reynolds Rhodesian Ridgeback Club of

the U.S. David and Carol Rice James Richmond Brad and Julie Rick Sue Rickson John Rickson James M. and Judith Ringler James R. and Carolyn Ringler Marcia Ritzenhein Rize Natural Energy Dale and Sonja Robertson *Rockford Construction

Company, Inc. **Rockford High School Boys

Lacrosse Rockwell Republic Eve Rogus and Paul Becker Bill and Mary Romence Root Lowell Manufacturing Co.*Ken Ross Rottman Family Charitable

Foundation John and Therese Rowerdink *Rowerdink, Inc. *

Donors (conTinueD)

G I V E T O D A Y A T V A I . O R G / G I V E3 3

Fred and Kathy Rozema Elizabeth Rushton Ruth’s Chris Steak House Robert and Linnea Rutkowski Alan and Margaret Ryan *S.A. Morman & Co. Chuck and Judith Samfilippo Sanders Foundation Ellie Sarafis Dwight and Jacquolyn Sawyer *Teresa Schaal Larry Schaidt Bill Schoonveld and Jan Laman Scott Mol Drywall, Inc. Peter and Joan Secchia *The Peter F. Secchia Family

Foundation **Ken Selleck Steve and Julie Shafley David and Jennifer Shane Blair and Michelle Sharpe George and Linda Sharpe George and Missy Sharpe The Sharpe Collection *John E. and Barb Shereda Nicholas and Karen Sherman Budge and Marilyn Sherwood *Donald and Ann Sicko The Silhouettes Six.One.Six Sunny Sjaarda Jason and Kimberly Slaikeu

Sarah Slater Brent and Diane Slay *Alexander Sloane Jack and Carol Smith *Special Events Party Rental, Inc. Spectrum Health *Robert and Beth Spica John and Judy Spoelhof

Foundation *Robert and Susan Stafford Frank and Dana Stanek Star Truck Rentals, Inc. Michele Stauffer Steelcase Inc. *Streamline Systems Inc. Thomas and Mary Stuit *Subway Development of

Western Michigan Summit Lawn Care and Snow

Plowing, Inc. Duke and Sue Suwyn *Synergy Marketing Solutions Marian Sytsma Taconic Charitable Foundation Michele Taipalus Roger and Sandra Tanis Team Hannah Team Troll *Tempting Tables *Patricia Ter Haar Teva Pharmaceuticals Elanore Thompson

Anthony Thompson Thousand Oaks Golf Club *Marilyn Titche *Todd Wenzel Buick GMC Julie Towner Townsquare Media * Tre Cugini *Tridelsol Triathlon Steve and Laura Triezenberg *Trinity Senior Living

Communities Julie Turner Twisted Rooster U.S. Bank National Association UCB, Inc. Union High School United Way, Heart of

West Michigan Urologic Consultants, PC Nancy Van Andel David and Carol Van Andel **David and Carol Van Andel

Foundation **Steve Van Andel **Philip and Patricia Van Baren Daniel and Ann Marie

Van Eerden *Donna Van Haren Gordon and Mary Van Harn *Randy and JoAnn Van Hoven Drs. Gordon and Margaret

Van Wylen *

George and Dot Vande Woude **Brian and Lori Vander Baan Stuart and Nelleke

Vander Heide *Allen VanderLaan Varnum LLP *Lawrence and Marsha Veenstra Jared and Morgan Veldheer Jim and Mary Veldheer *Howard and Brenda Veltman Veolia Energy Grand Rapids

LLC Via Design, Inc. Vintage Wine Co. Lonnie Vis Visual Entities Inc. Vivian G. Anderson Trust Phil and Kathy Vogelsang Al Volansky Vredevoogd Heating

and Cooling W.A. Lettinga Investment Waara Dawdy Invitational Alice Walls The Warehouse Ministry Warner Norcross & Judd LLP **Webb Chemical Service Corp. John Weller Wells Fargo N.A. *Richard and Diane Wendt West Michigan Forest Products

West Michigan Hockey Youth Foundation

West Michigan Hockey, Inc. West Michigan Sports

Commission West Ottawa Public Schools *Westfield Capital

Management Company Peter and B.J. Whigham Whitecaps Community

Foundation *David and Anne-Lise

Whitescarver *Sally Wierda Scott and Rebecca Wierda Steven and Juliana Wilkening Paul and Laura Williams Jim and Sue Williams *Keith and Jenna Winn Stephen and Debra Wittenbach Nathaniel and Lisa Wolf Wolverine Worldwide, Inc. *Women’s Lifestyle Magazine John and Kathleen Workman *Eric and Shawna Xu Young & Young Architects,

Inc. P.C. Liam Sullivan and Linda

Zarzecki James and Jane Zwiers David and Beatrice Zylstra

sources of funDing for operaTing anD overheaD eXpenses

* Leadership Society recognizes donors who have given more than $10,000 to the Institute. ** Legacy Society recognizes donors who have given more than $100,000 to the Institute.

16% Grant & Contract Revenue (Indirect)

84% Endowment Income & Other Revenues

3 4 v a n a n d e l i n s t i t u t e

Many of our supporters choose to celebrate an individual or special occasion with a gift to Van Andel Institute. We appreciate your contributions and celebrate with you.

Amani AlnaimiAurora Hair Studio Salon

Bruce ApplebachClinton and Joanne Hop

Tony and Kathleen AsseltaTony and Marjorie Biondi

Harlan BerensVerl and Vicky Bleeker

Traci BotruffWinn Setchfield

Barbara and William BradleyJames and Sheral Bradley

Angie CookThe Sorokin Family

Dick DawdyWaara Dawdy Invitational

Mindi DeSanctisJoseph and Nicole Infante

Vera DougherWilliam and Barbara Bradley Edward DzwonkowskiArline C. Dzwonkowski

Joyce FalkoThe Stephenson Family

Laurie FitzgeraldProgress Chemical, Inc.

Kristianna FlamboeCurtis and Pamela Bosch

Elizabeth A. FosterSands of Elk Rapids Condo Association

Aaron GarrettDianne Garrett

Daniel GarrisonMaryanna Johnson

Diane GeddesPaul and Charlene Fitzpatrick

Diane GohlkeKeith Gohlke

Jim GrimwadeDave and LeeAnn Abel

Roger HaebichDavid and Gloria Haebich

Brooke HesterCarrie BurnettNancy NewmanSarah TaylorMartha Thomases

Irene HoffmanLyle and Amy Karp

Liz HubbardLawrence and Darlyn Merryweather

Robert R. IsraelsClinton and Joanne Hop

Clayton KendallDiane AthertonSara Hop

Rose KarpLyle and Amy Karp

Edward KnowlesGerald Sajewski

John J. LantingJim Lanting

Olivier LeclercqOlivier and Nathalie Leclercq

Gabriella A. LynchLeo Spano

Alex MandarinoDane PaulsenJustin Weissert

Joyce MertensLaura R. Adkins Rebecca ArmstrongAdam ConradMatthew GlynnCatherine GoetgeluckKathy Martin Ted MertensKatie PetersonSarah PetrusakJoshua PriehsMatthew TurnerHolly Vanderlinde Sheryl Vanderlinde

Ian MurilloIan Murillo

Daniel NardiDonna M. Davis

Bill and Sandi NicholsonCarolyn P. Amory

Jeffrey O’HearnTom and Gerry Newby

Ron ParksArthur and Janice Schmude

Stu PostChristopher DeWitt

Denise PrayMichael DeBoer

Kathy RabachLaura R. AdkinsKathy MartinHolly VanderlindeSheryl Vanderlinde

Garrett ReinartzJohn and Amy Reinartz

Katelyn Mai ReynoldsRandall and Anna Reynolds

Ed RoutzahnMargaret Podworski

Fred RozemaTami Sytsma

Frank RutherfordRutherford & Associates

Jerry SeemanGary Arthur

J. Richard SlaytonJames Slayton

Jack and Carol SmithJeffrey and Monique EardleyMark EardleySteve Hutchison

Dan SpringerBrian AndersonMark BonnemaSteve BossenbroekDave BurgessPeter T. CampbellLinda ConnallyKim DamatoTimonthy DaumDerek EmersonJeff GrayMargaret HissPamela HoffmasterEvan HunterSteve HutchisonRichard KillianTim KoenigsknechtPaul KorteBrian RigneyAdam RolinskiMegan SeeberJuanita SharpeJack B. SmithCarol SpringerDan SpringerTrey SpringerPaul Terranova Jill WhalenJohnnie Woods

Lilliana TanisAlaina AnsonPhillip and Nicole DemeterGerald and Maria HomrichKenneth LarmPatrick and Debra LonerganMichael and JoAnn Mooney Brian and Victoria SzubinskiElanore M. Thompson

David and Carol Van AndelMark and Anne ElveDan and Lou Ann GaydouMartin and Peggy GreydanusMichael and Sue JandernoaJohn and Nancy KennedyAl and Robin KoopBrian and Lori Vander Baan

John VaughanDani and Suzanne Kardasz

J. Roger VosMatthew and Shari Berger

Bob and Ola WaaraWaara Dawdy Invitational

Gerald WaldronAustin and Reathel Waldron

Brian WhalenRobert and Betty Congdon

Anne-Lise WhitescarverRoger and Marcia Beutner

Florence ZiehmRamona’s Table

TriBuTesThese gifTs honor a family memBer, frienD or colleague wiTh a conTriBuTion To The insTiTuTe in 2013.

G I V E T O D A Y A T V A I . O R G / G I V E3 5

“100% of your partnership goes directly to research and education to shape the future of disease treatments and therapies.”

–David Van Andel

3 6 v a n a n d e l i n s t i t u t e

For our friends who have lost a loved one, we mourn with you. We appreciate your trust in us to fight disease in memory of your family and friends – with the hope for a healthier tomorrow.

Allison AardemaSteven and Julie Aardema

Will AbernathyKaren Hampton The Warehouse Ministry

Robert and Vivian AndersonDavid and Lynne Robinson

Lois AndersonRobert L. Anderson

Cindy AntonidesRicky and Debbra Yeager

Brooks ApplegateStephen Haarman

Frank L. ArcherBill and Janet AnspaughJonathan and Nancy BakerRandy and Sandi BrownNancy KainGary and Mary HerderBarry and Sharon HutzelMark and Barbara MartinieRaymond and Laura RosadoKen and Candi SchneiderTye and Gretchen StarrTimothy and Marcye Van DykePhilip and Erin Vontom

Wayne BakerCarole Yost

C.J. BarcelowShaun Barcelow

Woodrow and Martha BarclayDaniel and Rene Savage

Nicole BeuschelSportsman’s Fin and Feather Club

Gregory BogertAnnonymous John and Joyce HamlinRichard JankeRichard and Margy RibbensGary and Pat Robinson

Carlos BolivarVirgilio Tavas

Mark M. BoyceJoseph G. Popiel

Ted BrewerMargaret H. Fondren

Shane R. BrickeyDubric

Carolyn BrockLyle and Jackie Irish

Charles A. BrownRichard Brown

Suzanne J. BucheBen and Nora Poquette

Keith BuckMarilyn HotchkissBarbara Swinehart

Braeden “SuperBub” BurgessKevin and Dawn BurgessDiane DalmKatherine Davis

Anna B. BurkeHome Instead Senior Care

Peter G. BylsmaCarol L. Bylsma

Frank CampbellLis CampbellPaul and Lynn Getzin

Margaret CarnesKimmy A. Carnes

Molly A. CaveraSteven and Julie AardemaAcrisure, LLCWilliam and Mary Beth BarkeleyJohn and Mary CarrierDavid CaveraJohn and Jane DeanJeffrey Elder and Karla Kjellin-ElderJames and Evelyn FlynnJeremy Forton and Heather

Hickey-FortonKelly and Elizabeth GrahamGrand Valley ArtistsSharon HamacherReginald and Delores HornStuart and Shannon HuntMary KjellinJames and Patricia KnowlesGregory and Jilleanne LauriaWilliam and Lynda LukeRandy and Marcia MacGeorgeLyle MetzgerDavid and Suzette Lynn MeyerJerome and Debra MontpasJames and Courtney MoskalCathy Oosse

Remember Eric - Fight Childhood Cancer

Stephan and Marilyn RinockJohn and JoAnn Watson

Earl ChristensenKaren J. Christensen

Michael J. ClelandMichael and Margaret AchornDaniel Barry and Kay WilsonGreg BernardoVirginia E. BoniSelma CohenCynthia M. CottenIlio and Leslie DiMascioRobert E. GesellLarry and Linda GrantCarleton and Mary Lou GriffinDick and Nancy GroffJohn HasluckDennis JonesCherryl G. KimberJudith LaPerreGerard L’EsperancePaul and Christine McGuireHugh and Patricia MooreLisa MyersRebecca OlsonTom O’RourkeRobert and Julie OsbourneElaine C. OswaldThomas PlunkettRetirement Income Solutions, Inc.Eric and Carol SerrTheresa A. ShieldsNancy H. StrongSusan ThompsonSusan B. UllrichCharles and Sylvia VellaJody Winkler

Larry CollerTrivalent Group

Betty CongdonRobert A. Congdon

Marian DammonElanore M. Thompson

Verna DanielsMary Scanlan

Jay A. DeBoeMichael J. DeBoe

Clare DeLoyElita J. Wood

Charlotta DenmanElanore M. Thompson

Elmer DeRoosLyle and Roberta Brockway

Westin DietzJanet McCann

Liam A. DiRomaBarbara A. BetorHelen D’AmicoAnthony and Theresa DesoShelley FleischmanRobert and Mary GratzNancy GuptonPeter R. KermaniThomas and Diane KulzerSandra E. LureyKathleen M. O’BrienMary W. SnyderSusan SolomonPatricia VoergWilliam and Kathleen Weir

Bert DocterAl and Joyce Docter

Paul A. DreherStephen Haarman

Kathleen DrennanCharles and Christine BoelkinsScott and Suzanne BosgraafPatrick and Kristine BradyStephen and Mary CohleParker de WaalStephen and Jayne HanauerJanet HarestadBrendan and Nan KellyMark MannNadine ManziDan McKinneyLinda Miller-HeysKimberly MoorheadPatricia Otley NeuhausJohn OlsonJames OtleyBrock PlumbMargaret ReasonBarry SchwartzJill StockiVivian VanDykeWater Tower Dental CareGreg and Laura WinjumRobert and Carole Yerkes

Clifford A. DrewMarlene DeBlasio

Robert H. DykstraTom and Lisa Smith

Oliver EmersonDale Austin and Carol Myers-AustinJacqueline BartleyDianne GlupkerMary L. GrahamDeb NykampDavid and Barbara PaulsonAnthony PerovichAlan and Lisa RettlerWilliam D. Reynolds

memorials

G I V E T O D A Y A T V A I . O R G / G I V E3 7

Peter J. SchakelJack and Carol SmithHubert and Ann Weller

J.F. ErhardsFred and Barbara Erhards

Billie FaberCaryn Tanis

Cathleen FarranKatherine BockheimDenny and Joyce DennisMitchell and Nadine FarranRichard and Bertha GephartGoodwill IndustriesGary and Karen KirkAndrew and Cynthia KozyckiDianne LeysDan and Kathy Uzarski

Maxine FewlessLyle and Jackie Irish

Jean FrickAllan C. and Barbara Lowe

William GeddesPaul and Charlene Fitzpatrick

Robert GezonDirk and Victoria Hoffius

Ethla “Ricky” GilmerCharlene Heeren

Paul J. GislasonSteven and Karen Ender

Susan GlueckertDavid and Cathy Sniegowski

Ray GoodsellMary AndresChristopher and Kelly Bell

Jim and Joanne SchendenEarnest and Kareen ThomasFrances Wiegerink

Ray GrahamPaul and Charlene Fitzpatrick

Ronald Alan Grimwade, Sr.Dave and LeeAnn Abel

Michael GustafsonRonald and Pamela AmatoDavid A. AndersonCheryl AshMitchell and Denise BarachCurtis and Mary Beth BaskinJeff and Cathy BayerJennine M. BeckmannMary S. BeckmannWilliam M. BeckmannMary Claire BerryKristan A. BlouinDave and Julie BosheaMike and Joanne BoylanAlex and Michelle BrattonDavid and Cathy BranerJoel and Karen BregmanEugene and Donna BroggiJulia A. BrongeCathie BucekThe Buffett Early Childhood FundDiana BurnsMichel K. CadeBrenda CalabreseLeslie A. CameliCareer Transitions Center

of ChicagoStephen and Patricia CarlsonBrian and Lori CarrollThomas and Laura CastagnoliKimberly A. CernekChicago Bulls/White Sox

Training AcademyChicago Youth ProgramsThomas and Maryann Ciccarelli

Joseph C. ClaytonDiane M. CollisonJohn and Linda ConwayGregory L. CouchKathleen M. CouchLauryn Taylor CouchThomas and Linda CusackKatherine DeVriesDave DickDowners Grove Junior

Woman’s ClubCathy DrakeMark and Sharon DuffyChristine EaganDavid M. EpsteinRichard and Nancy EulerLaura M. FieldFirst Friday Club of ChicagoJames and Dorothy FoxMike GalwayMargaret D. GamboaRichard and Eula GoffKathleen GoldenPatricia GoldenGina GrahamJoan GrassmanMichael and Suzanne GreeneSandy GregoJohn GuarinoAllen and Patti GustafsonDina HallJeff and Lori HalldowLaurie HargroveKevin and Gina HartlerAnn-Marie F. HartlineWilliam and Cynthia HassettMike and Theresa HawleyMary Jo HazardRussell and Debbie HedrickMary F. HepburnSandy HigginsKatharine A. HolzerClifton and Betty HooksJudd HutchisonHenry and Susan Jacobi

Carol JalaliAnita JenkeMilind and Mrinal JoglekarMonica Kean and Mike RekruciakKennedy Junior High Home

& SchoolTeresa T. KerrPeggy KnottKen and Norma KolbetKristen KrainrathElaine and Alicia KrebsDarlene KrullLever InteractiveJohn and Peggy LeweL. W. and J.V. LewisSteven and Karen LindahlJodi LongMary LothropMark LoweFrances LuehrsGary M. MackDaniel and Beth MaguireGeraldine MahoneyMary E. MartinCharles and Josie MartinezJill MatesicFrank and Beverly MayerBarbara B. McCardellJerome and Amy McKeownSusan E. McLeanKevin and Margaret McNicholasRichard and Cheryl MealleLaura J. Mellencamp-MurphyThe Men’s Club of

St. Margaret Mary ParishMargaret MinickAlbert MitchellRichard and Deborah MitchlerThe Moffa FamilyPatricia A. MolloTom and Sue MurrayBetsy NagodeJohn and Christina NassosJim and Carol NaughtonKaren Noble

Shawn and Jennifer NolanKathryn O’ConnellKathleen OlsonThomas and Susan O’MalleyTina OrosEileen and Mary O’SheaThe O’Sullivan FamilyOunce of Prevention FundJohn C. and Jane Marie ParkerPatricia S. PattonKaren PetroLinda PfeifferPaul Stephen and Anna

Marie PettigrewNaperville North High School

Girls’ GolfPatrick and Alana PlaczkowskiPatricia C. PothKathleen E. PowersAllan and Donna PozdolJames QuaidDeborah RamseyRDG Schutte Wilscam Birge Inc.Robert and Mary Jane ReardonJohn M. RoetterPeggy A. RothMary RungerPaul and Nancy RutkowskiRobert and Linnea RutkowskiThe Ryan FamilyBarbara J. RyanGail P. Ryan-AndersonJames M. RyanElaine S. SabrieSaint Joseph’s UniversitySalvitti FamilyPaul Mary Beth SanchezHarry and Carolyn SheehyCharles and Elizabeth ShutyLaura SikorcinRoy and Joyce SkoogGregory SmithGeorge and Jo SpindlerChris andLori StanicekLynn Stasior

Janet M. StevensonGene SullivanHelen SuntkenSyntrinsic Investment Counsel, LLCTracy and Marsha TuckerEric and Marlene UstianJohn and Ramona VaikutisNancy Van VolkenburgEdward and Dennise VaughnMary Jane VerikThomas and Pamela VincentFox Valley VolkswagenAnthony VolpeThe Vrankin FamilyChris M. WagnerPhilip and Sandra WarnerDaniel and Donna WeaverScott and Jackie WebbPaul and Karen WeinewuthWest Chicago Elementary School

District No. 33Robert and Dee WiedemanFelice WilliamsJohn A. and Mary WilliamsWilliam and Marie YaculloAlbert YaoLaura Young

Carol A. HaarmanStephen Haarman

Patrick L. HammondPhyllis HammondSteve HammondTom PhamRockford Construction

Company, Inc.Randy and Vicki Schild Ronald and Julie Schild

Bruce L. HansenJoette HansenPatricia Ter Haar

3 8 v a n a n d e l i n s t i t u t e

Rosemarie HavilandDenise Fedko

Lynn HawkerDave and Deborah Wurfel

Elwyn HawleyBetten Chevrolet, IncThomas KrupiczewiczSandra SpencerRobert and Margaret Steketee

John HeerenRaymond and Sandra GajtkaJames and Janice Heeren

Steven M. HertelMary BallantineAntoinette HertelDaniel and Barbara KeithCraig K. Kempf Funeral Home, Inc.Kay McKeagueSam and Joanne McKeeverGerald and Deborah Myers

Donald HesselschwerdtJames and Florence Bouwman

Jim HickeyCatherine Amodeo

Ken HoltvluwerJune Holtvluwer

James and Dorothy HorganDavid and Nancy Flower

Carole HubbardCharles and Carole Johnson

Mary Louise HuffmanHedrick Associates

Tom HuizinghDavid and Sallie Brinks

Edward HusseyTed and Kathleen HillaryMark M. HuberDorothy KeyMarcus KeyMargaret KeyElaine RobinsonPatty SchlichtRobert and Katherine VanKlaveren

Patricia HutchingsODL, Inc.

Annette JackmanRichard and Patricia Cebelak

Wesley JaegerTodd and Dawn CutlerJeremy EatonSteven and Alyce Marie EmbreeMichelle HussRobert JacksonDuane JaegerLyndsey NelsonMatthew Nelson

Marcia A. JakolatLynda AllenPatricia F. CrowVern and Mary JakolatDianne MaitnerEmil and Yvonne Reinke

Dale JehnzenFloyd and Mary Patrick

Sally JenkinsAnn Jarchow

Kevin JohnsonLyle and Jackie Irish

Sarah D. KaperSteven and Julie AardemaJean Behnke

Dustin and Robyn BestemanDavid and Terri BoomstraAlan and Susan BranderJohn and Mary CarrierMark and Valerie ChulskiRalph and Majiel CostanzoRoger L. and Shara DeVriesThe Elzinga FamilyScott and Linda FolkertGeorgetown Bible ChurchHudsonville Public SchoolsMark HuizingaKathryn A. HutchinsJenison High Class of 1978Tracy KapengaRandy and Marcia MacGeorgeHollis and Carol McCullickJames and June MessinaTerry and Cheryl MeyerJ.L. and Emma MillerRichard and Deborah NykampTom and Pam OosterbroekBradley and Richelle RhowmineRandall and Anna ReynoldsPerry and Nora SellersMatthew and Cherie SielLeonard and Leonora SmitLarry and Virginia VeldinkKevin and Tracey WebergJohn WellerCarole Yost

Brigitte KleinselbeckDavid and Sallie Brinks

Alva J. KloosterDonald Klooster

Elizabeth KlopcicDonald Klopcic

David KostenMichael DeBoer

Chad KowalczykEsther Kowalczyk

Leon J. KowalczykEsther Kowalczyk

Patricia R. KozalCecilia PiusPulmonary Associates at

Mercy Health

Julia KrakerDavid and Sallie Brinks

Cody KruegerJan Ahlstrom

Beatrice R. LockeLyle and Roberta Brockway

Allan C. Lowe, Jr.Allan C. and Barbara Lowe

Michelle Marie LunnMichael and Suzanne Lunn

Dennis and Christine MaatmanJoel and Maybeth Maatman

Nel MakarewiczKaren R. AlgerLarry and Shirley GentherJanice Kenna

Alex MandarinoJames Briles

Robert MarkhamChad and Katie AppoldDeborah GretherEldon and Denise GrubbDick and Sandy G. HansenCarol HolquistGary and Rebecca KnappJeffrey and Diane Olson

Sharon PeaseSharon SanfordWarren SchutDaniel and Jacquelynn VanderlugtLois Veenstra

Johannes C. MarttinMichael and Christina Norris

Robert MartinRyan and Angie Stumpo

James Michael McCoyGeorge and Dot Vande Woude

Judith Mary McKenneyWard and Shirley McKenney

Janet McMainsLori Pospiech

Gary L. MeyeringMichael and Mary Dykema

Ken MiedemaKenneth and Judy BetzAgnes J. BeukemaMary DechowDonald and Ruth DeWinterMarvin and Ruth De WinterEllen J. DoornSue GrassmidGordon and Judith HaanKevin and Karen JohnstonJames and Joan KoetjeRobert and Helen LynemaBetsy Miedema

George MilanMaryAnn Maloley

Ernest MillerJohn and Sandra DoumaSusan HessRuth Tol

John C. MungerJeffrey and Tammy Ammon

Jane NicholsJean Swaney

Theodore A. NicoletteEleanore Nicolette

Bonnie NothoffPaul and Charlene Fitzpatrick

Marilyn ObuchowskiRuth Van Valkenburg

Carol ParkerRobin Kaplan

Diane PauwlChris Allen

Denise PicardatAAAEAmwayRobert and Roseann BensteinKari BlanchettJames and Deborah CookDaryl and Connie DelabbioExperience Grand RapidsPhil and Patricia HillMark and Lisa KarisKent County Board of

Commissioners/AdministratorKent MaurerLight & Breuning, Inc.Ellis and Debra LuchiesNorthern AirBrian PicardatPrein & NewhofRS&HDaniel and Wendy Sheilds

memorials (conTinueD)

G I V E T O D A Y A T V A I . O R G / G I V E3 9

Fiore PintoAna BruniMario and Geraldine ContrerasChris and Andrea SzczygielSteven SzczygielRonald and Lori Anne ThomasGeorge and Dot Vande Woude

Ed PodworskiMargaret Podworski

Bert PurwinPhyllis Purwin

Tony RahmeMaryAnn Maloley

Ryan J. ReganMatthew and Diana Bushman

Annette ReynoldsRaymond BardwellJack and Mary FrickJamie and Gerilyn MayMichael and Jane OlejniczakLiam Sullivan and Linda J. Zarzecki

Louise RiceJacqueline Winquist

Ricky L. RobertsJames and Betty McDonaldMetro Health Cedar SpringsJames and Sandra Perrin

Earl RobinsonDavid and Lynne Robinson

Doris RobinsonDavid and Lynne Robinson

Carrie RoeThe Bestrom Family

David L. RossiAnne M. Rossi

Alan R. RyanJean Swaney

Dennis SanfordSharon Sanford

Elizabeth SarafisLinda Triant

Joanne SauterGeorge and Linda Sharpe

Elizabeth SavickasAnonymousPatricia E. O’BrienProgressive SurfaceGregory and Kathleen ProulxAnna SavickasLoretta A. SavickasTri-County Country 4-H Club

Dwight W. SawyerJacquolyn Sawyer

James & Char SchierbeekJerry Broersma

Chester SchutClinton Hop

Frances ShadowensRobert and Elaine BostelaarJoe and Rose Cramer

Joseph J. SheetsVoyager

Rosetta R. ShipleyJames Richmond

Stephanie SpicerMathew and Jennifer Fahrenkrug

Harold SteeleNorth American Machine &

Engineering Co.

James SteeleWin and Kyle IrwinReg KloosterAl and Mary SmithThomas and Diane Thompson

Ruth E. SteeleFrank and Leslie Vander Hoff

Campbell H. SteketeeElizabeth J. Crosby

Walter StenborgPatrick and Alana Placzkowski

Cole StoddardCoins for ColeJohn and Jacqueline HerroldDavid and Anna Stoddard

Clarence SuelterCarl and Jenifer Nelson

Billy SwaneyClayton and Claire Kelly HardonJean SwaneyJennifer SwaneyTom and Sue Swaney Family

Rusty SwaneyBill and Nancy SwaneyTom and Sue Swaney Family

Bernard SytsmaMarian Sytsma

Lottie SzczepanekStuart and Nelleke Vander Heide

Karen TanisAnn BarrengerDonald and Mary DaviesCarol A. GrahamPaula M. HinelineRichard HorvitzLake Michigan Credit Union

The Langridge FamilySherri L. NitzTracy ReimusGary and Nancy RodgersRandy and Natalie SlujaNelson and Mary Wilner

Daryl Ter HaarPatricia Ter Haar

Clara ThompsonLee and Brenda Thompson

Tru TurkenburgPhilip and Mary Ellen Bloem

Rita UrbanShawn and Gail Quinn

Jay and Betty Van AndelAnonymous Lloyd F. LampellFrank Padron

Cliff Van HovenRandy and JoAnn Van Hoven

Gordy VandenBergKaren VandenBerg

Florence VanderveenNorman and Carolyn BoeveKenneth and Sharon KarstenNational Christian Foundation

West MichiganWilliam and Yvonne Van Ee

Carl VanderZee Sr.The Family of Carl VanderZee

Marjory VeliquettePaul and Charlene Fitzpatrick

John VibertAlexander Sloane

James VintonMary HarrisDonald and Ann Sicko

Marlene VisAnonymousMike and Joanne BoorsmaRon and Pat ButlerFreightliner of Grand RapidsMarvin and Nelvina IlbrinkJoseph KresovskyRuth M. LeyendeckerAlvin and Barbara MasselinkKathleen F. NautaCelia SommerfeldtStar Truck Rentals, Inc. Jeremy TertzakianLonnie Vis

Linda WasyluwskiRoger and Marcia Beutner

Kelsa WatsonJames and Debra Watson

Debbie WentworthDawn Campbell

Marian WestrateGary Westrate

Kay WhalenMichael J. Whalen

Peter WhighamPeter S. and B.J. Whigham

Jeffrey WierengaWill BarresiCrowe Horwath LLPCaroline GottwaldDavid and Judy HopkinsRandall and Marijo KnollGordon and Evelyn OevermanR4 Enterprises, LLCChris Robb

Rockford Construction Company, Inc.

Jane Thelen

Ellen WilderThe Bestrom Family

Nona WirtHoward H. Wirt

Greg WolfDan and Diane HickeySteven and Mary Jo Klotz

Casey WondergemRaymond and Marlene Wondergem

Carol WrightCAZZ Consulting

Virginia WynaldaPeggy CouturierArnold and Margie DeHavenTimothy and Margo DeWittGary and Elizabeth GingrichDavid JasperRick JohnsonSteven and Suanne Shoemaker

Gene YostCarole Yost

Sandy ZakemJohn and Jane Nichols

Herb ZeitterShirley Zeitter

4 0 v a n a n d e l i n s t i t u t e

Purple Community is filled with individuals and organizations joining together in fun ways to offer hope, support, and real action against disease. From sports events to jeans days at work, your events raised more than $250,000 for research and science education in 2013.

Ada Christian School “PurePlay Goes Purple” Basketball Games

Aquinas College Men’s and Women’s Purple Lacrosse Game

Aquinas College Purple Baseball Game

Aquinas College Softball - Christy’s Cause

Aquinas College Purple Volleyball Game

Art on Canvas Purple Night

Battle Creek Blaze Purple Flame Game

Body by OH Purple Challenge

Byron Center High School Volleyball Game

Caledonia High School Girls Cancer Awareness Game

Covenant Christian High School Purple Volleyball Game

Duncan Lake Middle School Cancer Walk

East Kentwood High School Breast Cancer Football Game

Eights for Hope Rowing Event

Fifth Third River Bank Run

Flounder and Marty’s Putt Putt for Purple

Flowerland Purple Community Give Back Month

Forest Hills Central Purple Basketball Game

Forest Hills Northern Purple Basketball Game

Generation Care’s Pedaling for Parkinson’s

Glow Run - Charity Partner

Grand Haven vs. Grand Rapids Catholic Central Purple Hockey Game

Grand Rapids Community College GRCC Cares Purple Week

Grand Rapids Griffins Purple Hockey Game

Grand Rapids Griffins Throw for Dough

Grand Rapids Marathon

Grand Valley State University Pre-SOMA Gail Easter Memorial 5k

Great Lakes Scrip - Team Member Purple Day

Holiday Inn Downtown Purple Pillow Promotion

HT Hackney Annual Golf Outing Benefiting Melanoma Research

Hudsonville High School Cookies for Cancer Fundraiser

J&H Oil Community Kick-Back Program

Jared Veldheer’s PowerStrength Benefit Fitness Class

Jenison vs. Hudsonville Purple Hockey Game

Jessie’s Ride for a Cure

Kenowa Hills Purple Hockey Game

Lee High School Volleyball Purple Tri-Tournament

Lowell/Caledonia/South Christian vs. Grand Rapids Christian Purple Hockey Game

Mancino’s of Greenville Parkinson’s Fundraiser

Mari J. Meyer Pancreatic Cancer Trail Run for Hope

Michigan Blood “One More” Blood Drive

Michigan Intramural Recreational Sports Association Purple Event

Miedema Asset Management Group Charity Auction Night

Mike “The Barber” Classic Golf Outing

Miles for Hope Brain Tumor 5k Walk/Run

Monica’s Cookies Purple Cookie Fundraiser

Oriole Park Elementary School Purple Hat Day

Ottawa County Juvenile Detention Center Charity Event

Pinewood Middle School Purple Basketball Game

Pure Barre Class to benefit Purple Community

Purple Community Leadership Academy

Putt for Parkinson’s Golf Outing

Detroit Red Wings Hockey Fights Cancer Night

Reeths-Puffer Public Schools Roof Off! Game On! Event

Reeths-Puffer Women’s Purple Soccer Game

River City Rascals Soccer Tournament

Rockford and Forest Hills Central RAMGER Lacrosse Purple Game™

Rosa’s Closet Give Back Charity of the Week

Russo’s of Kentwood Give Back Night

Seva Yoga Charity Night

Team Troll - Brann’s Steakhouse & Grille Partnership

Team Troll - Ice Fishing Tournament

Team Troll Cycling Team

The Color Run - Purple Color Zone

Tridelsol Triathlon

Uccello’s Restaurant Give Back Day

Union High School Purple Volleyball Game

Urologic Consultants Prostate Cancer 5K Race

Vytautas Aid Society Golf Outing

Wells Fargo Jeans Days

West Michigan Whitecaps Purple Baseball Game

West Ottawa Purple Power Basketball Game

Whitehall High School Purple Soccer Game

Wyoming High School Softball - Christy’s Cause

Yoga HEAT Purple Nights

PurPle Community evenTs

G I V E T O D A Y A T V A I . O R G / G I V E4 1

Special Events are opportunities to celebrate our success and invest in the future. We are fortunate to have extraordinarily dedicated signature special event sponsors whose generosity provided more than $1 million for research and science education in 2013.

The Acorn Grille at Thousand Oaks Golf Club

Alfresco LandscapesAmicus ManagementAmway Amway Grand Plaza HotelAonAquinas CollegeArtistryTony and Kathleen AsseltaBank of America

Merrill LynchBar DivaniBarnes & Thornburg LLPBDO USA LLPBella FursBill and Amy BennettBerends Hendricks Stuit

Insurance Agency

Blue Cross Blue Shield of Michigan

Bluewater TechnologiesChuck and Christine

BoelkinsBruce Heys BuildersBrush StudioCalvin CollegeScott and Heidi CampbellCancer and Hematology

Centers of Western Michigan

CARNEVALECascade EngineeringCascade Rental CenterCentury Floor SpaceCertified Tile and Stone

InstallersCityFlats HotelCitySēn LoungeThe Chop HouseColliers International Love and Valeda CollinsColor Me In GRComerica BankCornerstone UniversityCrowe HorwarthThe Crown Jewel Spa

and SalonCumulus MediaCuster, Inc.Cynthia RoseDave Bouwkamp MasonryDavenport University

Jerry and Karen DeBlaayDeloitteDesign 1 SalonDetroit Red WingsDick and Betsy DeVos

Family FoundationDouglas and Maria DeVos

FoundationRichard and Helen DeVos

FoundationDK SecurityEast End Plumbing

CompanyEast Grand Rapids Varsity

Football TeamEenhoorn LLCEikenhout, Inc.Ellis Parking CompanyMark and Jennifer EllisDr. Kathleen EllsworthErhardt ConstructionErnst and YoungEurest ServicesExpression Rings of HopeFairly Painless AdvertisingFerris Coffee and NutsFifth Third Private BankFinlandiaFred L. Hansen

CorporationGenesis Media ServicesGerrit’s Appliance Gilmore Catering Glass Concepts

Incorporated

Dr. Martin and Peggy Greydanus

GR OutdoorGrand Rapids Christian

High Varsity Football Team

Grand Rapids GriffinsThe Grand Rapids PressGrand Valley State

UniversityThe Granger GroupGreat Lakes Granite WorksGreat Lakes PavingGreat Lakes Scrip CenterGuts BrandingDr. Jana HallHansen Balk Steel Treating

CompanyThe Harris BuildingHastings Manufacturing

CompanyPaul and Sheryl HaverkateHedke PaintingHerman Miller FoundationHope CollegeHoward MillerHuizenga GroupThe Allen and Helen

Hunting FoundationIce Sculptures LTDThe ICN FoundationAndrew and Christina KellerJohn and Nancy KennedyKerkstra PrecastCraig and Debra Kinney

Al and Robin Koop Foundation

Korbel California Champagne

Mike and Sue JandernoaLake Michigan Credit

UnionLambert, Edwards &

AssociatesJeannine and Ray LanningLaura MercierLaw WeathersLeigh’sLennon Media

ManagementLeo’s Gary and Vicky LudemaMartha’s VineyardMeijerThe Veldheer, Long,

Mackay & Bernecker Group of Merrill Lynch Wealth Management

Metro CupcakesMetro HealthMichigan State University

College of Human Medicine

Mika Meyers Beckett and Jones

Jamie R. Mills, Mills Benefit Group

Jamie R. Mills, Mills Benefit Group. A Lighthouse Company

Modern Day FloralMike and Rachel Mraz

Brad and Leslie NelsonNorris, Perné and FrenchOlympia EntertainmentOne Trick PonyORG West MichiganOtterBasePapers PlusPeter C. & Emmajean Cook

FoundationPioneer ConstructionPitsch CompaniesPNC BankPreusser JewelersQuality Air ServiceRegal Financial GroupRescom Electric Inc.Rita Girls BakeryRize Natural EnergyRockwell RepublicRomence Gardens and

GreenhousesRoot Lowell ManufacturingRowerdink, Inc.San Chez Bistro and CaféScott Christopher HomesScott Mol Drywall, Inc.The Peter F. Secchia FamilyThe Sharpe Collection of

Premium AutomobilesSix.One.SixSmooch Beauty BoutiqueSpecial Events RentalSpectrum Health

Robert and Susan StaffordState Farm Insurance

Marsha Veenstra AgencySteelcase, Inc.Streamline SystemsStudio K Clothing

CompanyThomas and Mary StuitThousand Oaks Golf ClubTodd Wenzel Buick GMCTownsquare MediaTre CuginiTwisted Rooster Universal Forest ProductsDavid and Carol Van AndelSteve Van AndelVarnumVeolia EnergyVia DesignVisual EntitiesWarner Norcross and

Judd LLPWells FargoWest Michigan LumberDavid and Anne-Lise

WhitescarverJim and Sue WilliamsWolverine WorldwideWomen’s Lifestyle

MagazineAaron and Amanda WongWood TV8Woodford ReserveYoung and Young

Architects, Inc.

signaTure special evenT sponsors

4 2 v a n a n d e l i n s t i t u t e

Left to right:

David Whitescarver Vice President and Chief Legal Officer Love Collins III Vice President of Development, Communications and Marketing Peter Jones, Ph.D, D.Sc. Van Andel Research Institute Research Director and Chief Scientific Officer David Van Andel Chairman and Chief Executive Officer Steven J. Triezenberg, Ph.D. Director of Van Andel Education Institute, President and Dean of Van Andel Institute Graduate SchoolJana Hall Chief Operations Officer

leaDership Team

G I V E T O D A Y A T V A I . O R G / G I V E4 3

David Van AndelChairman and Chief Executive Officer, Van Andel Institute

James B. Fahner, M.D.Chief of Hematology/Oncology, Helen DeVos Children’s Hospital

W. Gary Tarpley, Ph.D.VP, Research & Development, Promega Corporation

George Vande Woude Ph.D. Distinguished Scientific Fellow, Van Andel Research Institute

Ralph Weichselbaum, M.D.Professor & Chairman of the Department of Radiation and Head of the Ludwig Center for Metastasis Research at The University of Chicago

BoarD anD council memBers

Van Andel Research Institute Board of Trustees

David Van AndelChairman and Chief Executive Officer, Van Andel Institute

James E. Bultman, Ed.D.Former President, Hope College (Not pictured)

Donald W. MaineFormer President, Davenport University

Juan R. Olivarez, Ph.D.President, Aquinas College

Gordon L. Van Harn, Ph.D. Emeritus Provost and Professor of Biology, Calvin College

Van Andel Education Institute Board of Trustees

David Van AndelChairman and Chief Executive Officer, Van Andel Institute

Michael JandernoaFormer Chairman of the Board and Chief Executive Officer, Perrigo Company

John KennedyPresident and Chief Executive Officer, Autocam Corporation

Ralph Hauenstein (Emeritus Trustee), President, Hauenstein Enterprises (Not pictured)

Van Andel Institute Board of Trustees

4 4 v a n a n d e l i n s t i t u t e

Chair: John CanepaMartin and Sue AllenRaymond and Alice AndrewsTony and Kathleen AsseltaJames and Shirley BalkJohn and Nancy BattsCharles and Christine BoelkinsJames and Donna BrooksGaylen and Susan BykerGerald and Suzanne CallahanJohn and Marie CanepaPresident Jimmy CarterLove and Valeda CollinsSam and Janene CummingsWilliam and Janice CurrieDavid and Karen CusterDaniel and Pamella DeVosDick and Betsy DeVosDouglas and Maria DeVosRichard and Helen DeVosJim and Gail FahnerJohn and Melynda Folkert

David and Judy FreyJack and Mary FrickDan and Lou Ann GaydouGene and Tubie GilmoreGary GrangerMartin and Margaret

GreydanusJana HallRalph W. HauensteinSteve and Brenda HeacockDavid and Joyce HechtJohn and Gwen HibbardDirk and Victoria HoffiusEarl and Donnalee HoltonRobert and Judith HookerAllen and Helen HuntingJosé and Sue InfanteWin and Kyle IrwinMike and Sue JandernoaSid and Cate JansmaJohn and Nancy KennedyCraig and Debra Kinney

Wilbur and Sharon LettingaRay LoeschnerTimothy and Kimberly LongGary and Vicky LudemaDonald and Kathleen MaineHank and Liesel MeijerLena MeijerMark and Mary Beth MeijerR. George MickelJack H. MillerJamie MillsLouis and Nancy MoranMark and Elizabeth MurrayTimothy and Denise MyersWilliam and Sandi NicholsonJuan and Mary OlivarezDonald and Ann ParfetDale and Sonja RobertsonMargaret RyanPeter and Joan SecchiaBudge and Marilyn SherwoodBrent and Diane Slay

Duke and Sue SuwynMarilyn TitcheSteve and Laura TriezenbergDavid and Carol Van AndelStephen Van AndelMichael and Michelle

Van DykeGordon and Mary Van HarnGordon and Margaret

Van WylenGeorge and Dot

Vande WoudeStuart and Nelleke

Vander HeideTheodore and Joan

VanderveenCheri VanderWeideDavid and Jayne VerLeeDavid and Anne-Lise

WhitescarverScott and Rebecca WierdaLinda Zarzecki and

Dr. Liam Sullivan

Co-Chairs: Heidi Campbell Rachel MrazZeke AlejosLindsay BenedictBrandon BissellScott and Heidi CampbellLinda Jo CarronNatalie ClearyAaron and Afton DeVosLeslie DruekeDawn Fiedorowicz-MacksonBo and Jenn FowlerMark Holtvluwer and

Wendy Parr HoltvluwerDr. Matthew and Sarah HudsonBrandi Jo HuyserPatrick Kane

Andrew and Christina KellerMichael LomonacoAlyssa LudemaJennifer MaxsonCasey McDonaldMichael and Rachel MrazMatt OsterhavenAndrew RobitailleCharles RowerdinkLindsay SlagboomDr. Jason and Kimberly SlaikeuChristopher SpainMegan SpruitJoshua J. StaffordAlison Waske SutterNathaniel WolfMegan Zubrickas

Hope on the Hill Board of GovernorsThank you, BoarD of governors

As members of the Van Andel Institute Hope on the Hill Board of Governors, your support of the Institute helps advance our efforts to improve the health and enhance the lives of current and future generations. Thank you for being our partners, serving as our ambassadors, and contributing significantly to our success.

J-Board AmbassadorsThank you, J-BoarD memBers

As J-Board members, you are leaders who exhibit the power of young professionals to make a difference. We appreciate the energy and dedication you bring to the Institute. Thank you for your vision and your friendship in our efforts to fight disease and advance our mission every day.

BoarD anD council memBers (conTinueD)

G I V E T O D A Y A T V A I . O R G / G I V E4 5

Michael S. Brown, M.D. Paul J. Thomas Professor of Genetics and Director of the Jonsson Center of Molecular Genetics, University of Texas Southwestern Medical Center – Dallas

Richard Axel, M.D.Professor of Neurosciences, Columbia University

Joseph L. Goldstein, M.D.Chairman of the Department of Molecular Genetics, University of Texas Southwestern Medical Center – Dallas

Tony Hunter, Ph.D.American Cancer Society Research Professor; Professor in the Molecular and Cell Biology Laboratory, Salk Institute; Director, Salk Institute Cancer Center

Philip A. Sharp, Ph.D.Professor of Biology, Massachusetts Institute of Technology; Head of the Cancer Center at MIT; Founder of Biogen Corporation

Alan Bernstein, Ph.D.President and Chief Executive Officer, Canadian Institute for Advanced Research

Joan Brugge, Ph.D.Chair, Department of Cell Biology, Harvard Medical School

Webster Cavenee, Ph.D.Director, Ludwig Institute for Cancer Research, University of California, San Diego

Frank McCormick, Ph.D.Director, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco

Board of Scientific Advisors

Scientific Advisory Board

James N. Boelkins, Ph.D.Former Provost of Hope College

Carol Van AndelExecutive Director, David and Carol Van Andel Foundation

Leanne Van Dyk, Ph.D.Dean and Vice President of Academic Affairs and Professor of Reformed Theology, Western Theological Seminary

Yvonne H. Van Ee, Ph.D.Professor Emerita of Education, Calvin College

David D. Baumgartner, M.D.Vice President of Medical Affairs, Saint Mary’s Health Care

Sally Camper, Ph.D.James V. Neel Collegiate Professor and Chair of the Department of Human Genetics, University of Michigan Medical School; Director of the Center for Genetics in Health and Medicine, University of Michigan

James B. Fahner, M.D.Chief of Hematology and Oncology, Helen DeVos Children’s Hospital

Thomas J. Haas, Ph.D.President, Grand Valley State University

Gordon L. Van Harn, Ph.D.Emeritus Provost and Professor of Biology, Calvin College

Van Andel Education Institute Advisory Council

Van Andel Institute Graduate School Directors

4 6 v a n a n d e l i n s t i t u t e

G I V E T O D A Y A T V A I . O R G / G I V E4 7

INSIDE BACK COVER

3 3 3 B o S t w I C K A V e N e G r A N D r A p I D S , M I 4 9 5 0 3

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