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Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University

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Page 1: Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University

Variation of Coronary Artery Anatomy in

Transposition of the Great Arteries

Piya SamankatiwatRamathibodi Hospital

Mahidol University

Page 2: Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University

Introduction

Anatomical variation of coronary artery in TGA is complicated.Literally, classification of coronary artery in TGA is inhomogeneous. The usual type is not that usual, only just slightly more than 60%Correct preoperative recognition is sometimes difficult.Influence on outcome of surgery is still controversial.

Page 3: Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University

Definition of coronary artery

Page 4: Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University
Page 5: Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University

Coronary artery morphology

Page 6: Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University

Patterns in TGA (Leiden Convention)

The “normal” coronary disposition in TGA is: 1LCx 2R (the disposition appears inverted as compared with the disposition in the normal heart). The most frequent anomalies encountered are: 1L 2RCx, 1Cx 2RL, 1R 2LCx, 2LCxR, 2RLCx, 2CxRL,1RLCx.These may pose special surgical problems or even contraindicate the switch at arterial level. in particular single coronary artery and intramural type.

Muresian H. Coronary arterial anomalies and variations Mædica A Journal of Clinical Medicine,

Volume1 No.1 2006

Page 7: Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University

Yacoub MH, Radley-Smith R. Thorax, 1978, 33, 418-424

Page 8: Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University

Wernovsky G and Sanders SP Coron Artery Dis. 1993;4:148–157.

Pasquali et al. Circulation. November 12, 2002

Page 9: Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University

Patients and method

An observational study20 consecutive patients underwent arterial switch operation.Anatomical patterns of coronary arteries were recorded.Special concern on difficult types.

Page 10: Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University

Results

Median age 12 days (3-480 days)Male:Female 3:114 newborns, 5 infants and 1 child One Dextrocardia

Page 11: Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University

Dextrocardia case

Page 12: Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University

Results

1LCx 2R 60% (n=12) 1 usual type with separated orifice of right ventricular branch from sinus 1. 1L 2RCx 25% (n=5) 2RLCX 15% (n=3) 2 cases posterior course of LCA1 case anterior course

Page 13: Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University

Results

1LCx 2R

60 %N=12

0 %1L 2RCx25 %N=5

2RLCx15 %N=3

0 % 0 % 0 %

Page 14: Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University

Conclusion

Coronary artery pattern in TGA was inconsistent.Usual pattern in only 60 %Difficult to determine if higher risk of arterial switch operation was associated with a particular type of coronary artery anatomy. Our series: all single coronary artery cases survive.The value of preoperative recognition of the pattern of coronary artery and outcome of surgery for TGA is still skeptical. Further observation

Page 15: Variation of Coronary Artery Anatomy in Transposition of the Great Arteries Piya Samankatiwat Ramathibodi Hospital Mahidol University

Thank you