vegf and the fab fragment of a humanized neutralizing antibody: crystal structure of the complex at...

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VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface Yves A Muller, Yvonne Chen, Hans W Christinger, Bing Li, Brian C Cunningham, Henry B Lowman, Abraham M de Vos Structure Volume 6, Issue 9, Pages 1153-1167 (September 1998) DOI: 10.1016/S0969-2126(98)00116-6

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Page 1: VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface

VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface 

Yves A Muller, Yvonne Chen, Hans W Christinger, Bing Li, Brian C Cunningham, Henry B Lowman, Abraham M de Vos  

Structure Volume 6, Issue 9, Pages 1153-1167 (September 1998)

DOI: 10.1016/S0969-2126(98)00116-6

Page 2: VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface

Figure 1

Structure 1998 6, 1153-1167DOI: (10.1016/S0969-2126(98)00116-6)

Page 3: VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface

Figure 2

Structure 1998 6, 1153-1167DOI: (10.1016/S0969-2126(98)00116-6)

Page 4: VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface

Figure 3

Structure 1998 6, 1153-1167DOI: (10.1016/S0969-2126(98)00116-6)

Page 5: VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface

Figure 4

Structure 1998 6, 1153-1167DOI: (10.1016/S0969-2126(98)00116-6)

Page 6: VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface

Figure 5

Structure 1998 6, 1153-1167DOI: (10.1016/S0969-2126(98)00116-6)

Page 7: VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface

Figure 6

Structure 1998 6, 1153-1167DOI: (10.1016/S0969-2126(98)00116-6)

Page 8: VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface

Figure 7

Structure 1998 6, 1153-1167DOI: (10.1016/S0969-2126(98)00116-6)