ventricular system lecture
TRANSCRIPT
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VENTRICULARVENTRICULAR
SYSTEMSYSTEMBy
Dr. Bernadett Pua Velasco
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QUESTIONQUESTION
Name the ventricles of theName the ventricles of the
brain (4)brain (4)
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Ventricles of the brainVentricles of the brain
Lateral ventriclesLateral ventricles
Third ventricleThird ventricle
Fourth ventricleFourth ventricle
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VentricleVentricle
Derived from the cavity of theDerived from the cavity of the
neural tubeneural tube
Lined by ependymaLined by ependyma
Filled with CSFFilled with CSF
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EpendymaEpendyma
Single layer of cuboidal/columnarSingle layer of cuboidal/columnar
cell that has microvilli and ciliacell that has microvilli and cilia
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QUESTIONQUESTION
Name the three groups ofName the three groups of
ependymal cells. Give theependymal cells. Give theimportance of eachimportance of each
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EpendymaEpendyma
Single layer of cuboidal/columnarSingle layer of cuboidal/columnar
cell that has microvilli and ciliacell that has microvilli and cilia
3 groups:3 groups: EpendymocytesEpendymocytes
TanycytesTanycytes
Choroidal epithelial cellsChoroidal epithelial cells
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Cerebrospinal FluidCerebrospinal Fluid
Clear, colorless fluidClear, colorless fluid
Found in the ventricles and in theFound in the ventricles and in the
subarachnoid space around thesubarachnoid space around the
brain and spinal cordbrain and spinal cord
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Cerebrospinal FluidCerebrospinal Fluid
Volume: 130mlVolume: 130ml
Rate of production: 0.5ml/minRate of production: 0.5ml/min
Composition:Composition:
15-45mg/100ml= CHON15-45mg/100ml= CHON
50-85mg/100ml= glucose50-85mg/100ml= glucose
# of cells: 0-3 lymphocytes/mm# of cells: 0-3 lymphocytes/mm33
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QUESTIONQUESTION
What is the Normal CSFWhat is the Normal CSF
PressurePressure
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Cerebrospinal FluidCerebrospinal Fluid
Pressure: 60-150 mmHPressure: 60-150 mmH22OO
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QUESTIONQUESTION
Give some instances whenGive some instances when
CSF pressure is increasedCSF pressure is increased
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Cerebrospinal FluidCerebrospinal Fluid
Pressure: 60-150 mmHPressure: 60-150 mmH22OO
Increased by:Increased by: CoughingCoughing
StrainingStraining
Compressing IJVCompressing IJV
Space occupying lesionsSpace occupying lesions inflammationinflammation
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QUESTIONQUESTION
Give some of the functionsGive some of the functions
of CSFof CSF
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Cerebrospinal FluidCerebrospinal Fluid
Functions:Functions:
Bathes the surfaces of the brain andBathes the surfaces of the brain and
SCSC Serves as a cushionServes as a cushion
assist in the regulation of contentsassist in the regulation of contents
of the skullof the skull Provides nourishment in the CNSProvides nourishment in the CNS
Removal of neural metabolismRemoval of neural metabolism
productsproducts
Endocrine influencesEndocrine influences
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QUESTIONQUESTION
What structure forms CSFWhat structure forms CSF
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Cerebrospinal FluidCerebrospinal Fluid
Formed by choroid plexuses ofFormed by choroid plexuses of
the lateral, third and fourththe lateral, third and fourth
ventriclesventricles
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Choroid plexusesChoroid plexuses
Core of folded connective tissuesCore of folded connective tissues
that are covered with cuboidalthat are covered with cuboidal
epithelium of the ependymaepithelium of the ependyma Free surfaces are covered withFree surfaces are covered with
microvillimicrovilli
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Cerebrospinal FluidCerebrospinal Fluid
CirculationCirculation
Choroid plexusesChoroid plexuses
Lateral ventriclesLateral ventricles
Third ventricleThird ventricle
Fourth ventricleFourth ventricle
Subarachnoid spaceSubarachnoid space
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QUESTIONQUESTION
What structure absorbsWhat structure absorbs
CSF in the brainCSF in the brain
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Cerebrospinal FluidCerebrospinal Fluid
AbsorptionAbsorption
Arachnoid villiArachnoid villi
Diverticulum of the subarachnoid spaceDiverticulum of the subarachnoid spacethat pierces the dura materthat pierces the dura mater
Venous sinusesVenous sinuses
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QUESTIONQUESTION
Enumerate the flow of CSFEnumerate the flow of CSF
from choroid plexuses tofrom choroid plexuses to
arachnoid villiarachnoid villi
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Cerebrospinal FluidCerebrospinal Fluid
CirculationCirculation
Choroid plexusesChoroid plexuses
Lateral ventriclesLateral ventricles
Third ventricleThird ventricle
Fourth ventricleFourth ventricle
Subarachnoid spaceSubarachnoid space
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QUESTIONQUESTION
Name the divisions ofName the divisions of
lateral ventricle (4)lateral ventricle (4)
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Lateral VentriclesLateral Ventricles
C shaped cavityC shaped cavity
Divided intoDivided into
Body (parietal lobe)Body (parietal lobe)
Anterior horn (frontal lobe)Anterior horn (frontal lobe)
Posterior horn (occipital lobe)Posterior horn (occipital lobe)
Inferior horn (temporal lobe)Inferior horn (temporal lobe)
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QUESTIONQUESTION
Name the communicationName the communication
between lateral ventriclebetween lateral ventricle
and third ventricleand third ventricle
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Lateral VentriclesLateral Ventricles
Communicates with the thirdCommunicates with the third
ventricle through theventricle through the
interventricular foramen (forameninterventricular foramen (foramenof Monroe)of Monroe)
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QUESTIONQUESTION
Name the communicationName the communication
between third ventriclebetween third ventricle
and fourth ventricleand fourth ventricle
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Third VentricleThird Ventricle
Slit like cleft between the 2Slit like cleft between the 2
thalamithalami
Communicates with the fourthCommunicates with the fourthventricle through the cerebralventricle through the cerebral
aqueduct (sylvius)aqueduct (sylvius)
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Fourth VentricleFourth Ventricle
Tent shaped cavityTent shaped cavity
Anterior to the cerebellumAnterior to the cerebellum
Posterior to the pons and superiorPosterior to the pons and superior
half of the medulla oblangatahalf of the medulla oblangata
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QUESTIONQUESTION
Name the communicationName the communication
between fourth ventriclebetween fourth ventricle
and subarachnoid spaceand subarachnoid space
(3)(3)
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Fourth VentricleFourth Ventricle
Communicates with theCommunicates with the
subarachnoid space throughsubarachnoid space through
Median: foramen of MagendieMedian: foramen of Magendie Lateral: foramina of LuschkaLateral: foramina of Luschka
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QUESTIONQUESTION
What are the 3 layers ofWhat are the 3 layers of
meninges (outer to innermeninges (outer to inner
layer)layer)
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MeningesMeninges
Pia materPia mater
Arachnoid materArachnoid mater
Dura materDura mater
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QUESTIONQUESTION
Enumerate the flow of CSFEnumerate the flow of CSF
from choroid plexuses tofrom choroid plexuses to
arachnoid villiagainarachnoid villiagain
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QUESTIONQUESTION
What is the normal CSFWhat is the normal CSF
pressurepressure
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Cerebrospinal FluidCerebrospinal Fluid
Pressure: 60-150 mmHPressure: 60-150 mmH22OO
Increased by:Increased by: CoughingCoughing StrainingStraining
Compressing IJVCompressing IJV
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QUESTIONQUESTION
What is hydrocephalusWhat is hydrocephalus
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HydrocephalusHydrocephalus
Abnormal increase in the volumeAbnormal increase in the volume
of CSF within the skullof CSF within the skull
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QUESTIONQUESTION
What are the causes ofWhat are the causes of
hydrocephalushydrocephalus
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HydrocephalusHydrocephalus
Abnormal increase in the volumeAbnormal increase in the volume
of CSF within the skullof CSF within the skull
CausesCauses Excessive formation of CSFExcessive formation of CSF
Blockage in the circulationBlockage in the circulation
Diminished absorption of CSFDiminished absorption of CSF
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QUESTIONQUESTION
What are the two types ofWhat are the two types of
hydrocephalus.hydrocephalus.
DifferentiateDifferentiate
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HydrocephalusHydrocephalus
CommunicatingCommunicating
Non-communicatingNon-communicating
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Thank you for listeningThank you for listening