ventricular system lecture

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    VENTRICULARVENTRICULAR

    SYSTEMSYSTEMBy

    Dr. Bernadett Pua Velasco

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    QUESTIONQUESTION

    Name the ventricles of theName the ventricles of the

    brain (4)brain (4)

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    Ventricles of the brainVentricles of the brain

    Lateral ventriclesLateral ventricles

    Third ventricleThird ventricle

    Fourth ventricleFourth ventricle

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    VentricleVentricle

    Derived from the cavity of theDerived from the cavity of the

    neural tubeneural tube

    Lined by ependymaLined by ependyma

    Filled with CSFFilled with CSF

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    EpendymaEpendyma

    Single layer of cuboidal/columnarSingle layer of cuboidal/columnar

    cell that has microvilli and ciliacell that has microvilli and cilia

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    QUESTIONQUESTION

    Name the three groups ofName the three groups of

    ependymal cells. Give theependymal cells. Give theimportance of eachimportance of each

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    EpendymaEpendyma

    Single layer of cuboidal/columnarSingle layer of cuboidal/columnar

    cell that has microvilli and ciliacell that has microvilli and cilia

    3 groups:3 groups: EpendymocytesEpendymocytes

    TanycytesTanycytes

    Choroidal epithelial cellsChoroidal epithelial cells

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    Cerebrospinal FluidCerebrospinal Fluid

    Clear, colorless fluidClear, colorless fluid

    Found in the ventricles and in theFound in the ventricles and in the

    subarachnoid space around thesubarachnoid space around the

    brain and spinal cordbrain and spinal cord

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    Cerebrospinal FluidCerebrospinal Fluid

    Volume: 130mlVolume: 130ml

    Rate of production: 0.5ml/minRate of production: 0.5ml/min

    Composition:Composition:

    15-45mg/100ml= CHON15-45mg/100ml= CHON

    50-85mg/100ml= glucose50-85mg/100ml= glucose

    # of cells: 0-3 lymphocytes/mm# of cells: 0-3 lymphocytes/mm33

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    QUESTIONQUESTION

    What is the Normal CSFWhat is the Normal CSF

    PressurePressure

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    Cerebrospinal FluidCerebrospinal Fluid

    Pressure: 60-150 mmHPressure: 60-150 mmH22OO

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    QUESTIONQUESTION

    Give some instances whenGive some instances when

    CSF pressure is increasedCSF pressure is increased

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    Cerebrospinal FluidCerebrospinal Fluid

    Pressure: 60-150 mmHPressure: 60-150 mmH22OO

    Increased by:Increased by: CoughingCoughing

    StrainingStraining

    Compressing IJVCompressing IJV

    Space occupying lesionsSpace occupying lesions inflammationinflammation

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    QUESTIONQUESTION

    Give some of the functionsGive some of the functions

    of CSFof CSF

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    Cerebrospinal FluidCerebrospinal Fluid

    Functions:Functions:

    Bathes the surfaces of the brain andBathes the surfaces of the brain and

    SCSC Serves as a cushionServes as a cushion

    assist in the regulation of contentsassist in the regulation of contents

    of the skullof the skull Provides nourishment in the CNSProvides nourishment in the CNS

    Removal of neural metabolismRemoval of neural metabolism

    productsproducts

    Endocrine influencesEndocrine influences

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    QUESTIONQUESTION

    What structure forms CSFWhat structure forms CSF

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    Cerebrospinal FluidCerebrospinal Fluid

    Formed by choroid plexuses ofFormed by choroid plexuses of

    the lateral, third and fourththe lateral, third and fourth

    ventriclesventricles

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    Choroid plexusesChoroid plexuses

    Core of folded connective tissuesCore of folded connective tissues

    that are covered with cuboidalthat are covered with cuboidal

    epithelium of the ependymaepithelium of the ependyma Free surfaces are covered withFree surfaces are covered with

    microvillimicrovilli

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    Cerebrospinal FluidCerebrospinal Fluid

    CirculationCirculation

    Choroid plexusesChoroid plexuses

    Lateral ventriclesLateral ventricles

    Third ventricleThird ventricle

    Fourth ventricleFourth ventricle

    Subarachnoid spaceSubarachnoid space

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    QUESTIONQUESTION

    What structure absorbsWhat structure absorbs

    CSF in the brainCSF in the brain

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    Cerebrospinal FluidCerebrospinal Fluid

    AbsorptionAbsorption

    Arachnoid villiArachnoid villi

    Diverticulum of the subarachnoid spaceDiverticulum of the subarachnoid spacethat pierces the dura materthat pierces the dura mater

    Venous sinusesVenous sinuses

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    QUESTIONQUESTION

    Enumerate the flow of CSFEnumerate the flow of CSF

    from choroid plexuses tofrom choroid plexuses to

    arachnoid villiarachnoid villi

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    Cerebrospinal FluidCerebrospinal Fluid

    CirculationCirculation

    Choroid plexusesChoroid plexuses

    Lateral ventriclesLateral ventricles

    Third ventricleThird ventricle

    Fourth ventricleFourth ventricle

    Subarachnoid spaceSubarachnoid space

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    QUESTIONQUESTION

    Name the divisions ofName the divisions of

    lateral ventricle (4)lateral ventricle (4)

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    Lateral VentriclesLateral Ventricles

    C shaped cavityC shaped cavity

    Divided intoDivided into

    Body (parietal lobe)Body (parietal lobe)

    Anterior horn (frontal lobe)Anterior horn (frontal lobe)

    Posterior horn (occipital lobe)Posterior horn (occipital lobe)

    Inferior horn (temporal lobe)Inferior horn (temporal lobe)

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    QUESTIONQUESTION

    Name the communicationName the communication

    between lateral ventriclebetween lateral ventricle

    and third ventricleand third ventricle

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    Lateral VentriclesLateral Ventricles

    Communicates with the thirdCommunicates with the third

    ventricle through theventricle through the

    interventricular foramen (forameninterventricular foramen (foramenof Monroe)of Monroe)

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    QUESTIONQUESTION

    Name the communicationName the communication

    between third ventriclebetween third ventricle

    and fourth ventricleand fourth ventricle

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    Third VentricleThird Ventricle

    Slit like cleft between the 2Slit like cleft between the 2

    thalamithalami

    Communicates with the fourthCommunicates with the fourthventricle through the cerebralventricle through the cerebral

    aqueduct (sylvius)aqueduct (sylvius)

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    Fourth VentricleFourth Ventricle

    Tent shaped cavityTent shaped cavity

    Anterior to the cerebellumAnterior to the cerebellum

    Posterior to the pons and superiorPosterior to the pons and superior

    half of the medulla oblangatahalf of the medulla oblangata

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    QUESTIONQUESTION

    Name the communicationName the communication

    between fourth ventriclebetween fourth ventricle

    and subarachnoid spaceand subarachnoid space

    (3)(3)

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    Fourth VentricleFourth Ventricle

    Communicates with theCommunicates with the

    subarachnoid space throughsubarachnoid space through

    Median: foramen of MagendieMedian: foramen of Magendie Lateral: foramina of LuschkaLateral: foramina of Luschka

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    QUESTIONQUESTION

    What are the 3 layers ofWhat are the 3 layers of

    meninges (outer to innermeninges (outer to inner

    layer)layer)

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    MeningesMeninges

    Pia materPia mater

    Arachnoid materArachnoid mater

    Dura materDura mater

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    QUESTIONQUESTION

    Enumerate the flow of CSFEnumerate the flow of CSF

    from choroid plexuses tofrom choroid plexuses to

    arachnoid villiagainarachnoid villiagain

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    QUESTIONQUESTION

    What is the normal CSFWhat is the normal CSF

    pressurepressure

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    Cerebrospinal FluidCerebrospinal Fluid

    Pressure: 60-150 mmHPressure: 60-150 mmH22OO

    Increased by:Increased by: CoughingCoughing StrainingStraining

    Compressing IJVCompressing IJV

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    QUESTIONQUESTION

    What is hydrocephalusWhat is hydrocephalus

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    HydrocephalusHydrocephalus

    Abnormal increase in the volumeAbnormal increase in the volume

    of CSF within the skullof CSF within the skull

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    QUESTIONQUESTION

    What are the causes ofWhat are the causes of

    hydrocephalushydrocephalus

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    HydrocephalusHydrocephalus

    Abnormal increase in the volumeAbnormal increase in the volume

    of CSF within the skullof CSF within the skull

    CausesCauses Excessive formation of CSFExcessive formation of CSF

    Blockage in the circulationBlockage in the circulation

    Diminished absorption of CSFDiminished absorption of CSF

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    QUESTIONQUESTION

    What are the two types ofWhat are the two types of

    hydrocephalus.hydrocephalus.

    DifferentiateDifferentiate

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    HydrocephalusHydrocephalus

    CommunicatingCommunicating

    Non-communicatingNon-communicating

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    Thank you for listeningThank you for listening