vestibular systems and the eyes: a n overview
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Vestibular systems and the eyes: a n overview. Ken Wu. Disclaimer. This tutorial is a simple and conceptual guide to the vestibular system and the eyes If there are any conflicts between my slides and the lecturers, THE LECTURER IS ALWAYS RIGHT… - PowerPoint PPT PresentationTRANSCRIPT
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Vestibular systems and the eyes: an overview
Ken Wu
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Disclaimer
• This tutorial is a simple and conceptual guide to the vestibular system and the eyes
• If there are any conflicts between my slides and the lecturers, THE LECTURER IS ALWAYS RIGHT…
• …maybe not always but they set your exams so if in doubt, refer back to their teaching
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Eye
• Structure + circulation– Learn from slides/anatomy textbook
• Movement• Light detection• Reflexes
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Intrinsic muscles of the eye
• Superior/inferior oblique– Abduct + depress + internal rotate/adduct +
depress + external rotate eyes• Medial/lateral rectus– Adduct/Abduct eyes
• Superior/inferior rectus– Elevates/Depress eyes
• SO4LR6AO3
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Testing the intrinsic muscles
• Superior oblique– Adduct then depress
• Inferior oblique– Abduct then depress
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Eye movements
• Saccade vs smooth pursuit• Duction– Movement in one eye
• Version– Movement in both eyes in same direction– Innervation to both eyes– Relaxation of antagonist muscles
• Convergence vs Divergence
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Light detection
• ‘Backwards’ retina– Sclera, photoreceptors, bipolar cells, ganglion cells
• Visual acuity– 20/20 means you can read at 20 feet what a
person with normal acuity can read at 20 feet• Colour– 3 cones: Red, Green, Blue
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Primary visual pathway
• Optic nerve• Optic chiasm• Optic tract• Lateral geniculate nucleus• Optic radiation• Primary visual cortex• Know your visual field defects!!!
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Reflexes
• Pupillary light reflex• The near response• Vestibulo-ocular reflex
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Afferent pupillary light reflex
• Rods and cones• Retinal ganglion• Optic nerve• Optic chiasm• Left and right optic tracts• Left and right pretectal nucleus• Edinger-Westphal nucleus
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Efferent pupillary light reflex
• Edinger-Westphal nucleus• Along oculomotor nerves• Ciliary ganglion– Synapse with parasympathetic
• Iris constrictor muscle
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Near response
• Triad– Pupillary miosis– Convergence– Accomodation
• Efferent = oculomotor nerve
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Reflex defects
• Optic (afferent) damage– Loss of ipsilateral direct and contralateral consensual
• Oculomotor (efferent) damage– Loss of ipsilateral direct and consensual
• Relative Afferent Pupillary Defect (Marcus Gunn pupil)– Partial optic nerve lesion– Pupil in affected eye appears to dilate in swinging-torch test
• Argyll-Robertson pupil– Can accommodate but cannot react
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The Vestibular System
• Located in the inner ear• Semicircular canals– Anterior vertical– Posterior vertical– Horizontal
• Otolith organs– Utricule– Saccule
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Semicircular Canals
• Detect angular acceleration• 3 sets covering rotation in the 3 planes– Anterior vertical = coronal (head – shoulder) – Posterior vertical = sagittal (head nodding)– Horizontal = transverse (head shaking)
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Mechanism - Demo
• Cilia of hair cells within endolymph• Inertia movement of endolymph causes hair
cells to deform• Displacement of hair cells causes
depolarisation
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Angular acceleration
• Bilateral stimulation• Rotation to one side stimulates the same side
AND inhibits the opposite side• There is a tonic firing rate – normally the left
and right balance out
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Otolith organs
• Detects gravity and linear acceleration• Saccule– Arranged in vertical plane– Hair cells are horizontal– Therefore detects vertical movement
• Utricule– Arranged in horizontal plane– Hair cells are vertical– Therefore detects horizontal movement
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Mechanism - Demo
• Cilia of hair cells covered by otoliths – a gelatinous matrix containing calcium carbonate crystals
• Inertia of otoliths cause hair cells to deform• Displacement of hair cells cause
depolarisation
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Gravity and Linear acceleration
• Once hair cells are displaced, they stay displaced– Therefore tonic firing exists in the saccule due to
the presence of gravity– It also means head tilt and lying down are also
detected even after several hours (e.g. sleep)• Inertia of the otoliths in linear acceleration
temporarily causes displacement of the utricule hair cells
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Vestibular pathways
• Vestibular nerve ganglion (Scarpa’s ganglion)• Vestibular nerve• Vestibulocochlear nerve• Vestibular nuclei– In the brainstem, at the floor of the 4th ventricle
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Vestibulo-ocular
• Vestibular nucleus stimulates contralateral VI nucleus
• VI nucleus– Abduct eye– Stimulates contralateral III nucleus – adducts
opposite eye• Causes vestibulo-ocular reflex– Head rotate left, eyes moves right to maintain gaze– Function is to maintain gaze
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Vestibulo-spinal
• Lateral vestibulo spinal tract– Ipsilateral– Influence limb muscles
• Medial vestibulo spinal tract– Bilateral– Influence neck and back muscles
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Vestibular disorders
• Vestibular nystagmus– Unopposed tonus of intact canal– Eyes driven to lesioned side– Fast saccade beat to intact side
• Vestibular ataxia– Unopposed tonus of intact canal– Body/head fall towards lesioned side
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Any questions?
• Email me at [email protected] or [email protected]
• Visit the ICSM Year 1+2 past paper bank Facebook group
• Good luck!