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The 20th International Taurine Meeting

Taurine and Brain Health

PROGRAM and ABSTRACTS

May 23-27, 2016The Plaza HotelSeoul, KOREA

By the Organizing Committee of the 20th International Taurine Meetingwww.taurine2016.org

THE 20TH INTERNATIONAL TAURINE MEETING MAY 23-27, 2016, SEOUL, KOREA

SPONSORS

Dear Taurine Scientists:

We are pleased to host the 20th International Taurine Meeting (INTAM20) in May 23-27, 2016 at the Plaza Hotel in Seoul, Korea. Since the 1st International Taurine Meeting in Tucson, Arizona, USA in 1975, we have held meetings all over the world, including the United States, Japan, Finland, Italy, Mexico, Spain, Germany, Morocco, and Poland. Each meeting has enriched our understanding of the physiological role of taurine, as well as helped to build our wonderful international taurine family.

Although the Seoul meeting will cover many areas of taurine research, our main focus will be on the topic of “Taurine and Brain Health”, which is one of the major areas of taurine research. It is our hope that the taurine research presented during this meeting will contribute to the pathogenesis, prevention and treatment of various CNS disorders. Taurine scientists from 15 countries will participate actively in 11 different scientific sessions and experience Korean culture by watching musical performances and visiting historical sites. More information is available at the INTAM20 website, www.taurine2016.org.

I am greatly appreciative of all the participating taurine scientists and the scientific committee members, as well as Seoul Metropolitan Government and Dong-A Pharmaceutical Company for their generous financial supports.

Sincerely,

Ha Won Kim, Ph. D.Chairman, the 20th International Taurine Meeting

The 20th International Taurine Meeting May 23-27, 2016, Seoul, KOREA

Advisory Committee

Byong Kak Kim (Seoul National University, Korea)

Eun Bang Lee (Seoul National University, Korea)

International Scientific Committee

Stephen Schaffer (University of South Alabama, USA)

Simo S. Oja (University of Tampere, Finland)

Shigeru Murakami (Fukui Prefectural University, Japan)

John Wu (Florida Atlantic University, USA)

Abdeslem El Idrissi (City University of New York, USA)

Janusz Marcinkiewicz (Jagiellonian University, Poland)

Eunkyue Park (Institute for Basic Research in Developmental Disabilities, USA)

Young Soo Kim (KIST, Korea)

Ha Won Kim (University of Seoul, Korea)

Organizing Committee

Chairman: Ha Won Kim (University of Seoul, Korea)

Secretary General: Kyoung Soo Kim (Kyung Hee University Hospital, Korea) and Young Soo Kim (Korea Institute

of Science and Technology, Korea)

Treasure & Travel: Young Sook Kang (Sookmyung Women’s University, Korea) and JungSill Lee (Kyungdong

University, Korea)

Registration: Chaekyun Kim (Inha University, Korea) and Mi Ja Choi (Keimyung University, Korea)

Academy: Kyung Ja Chang (Inha University, Korea) and Sung Hoon Kim (Konkuk University, Korea)

Publication: Dong Hee Lee (University of Seoul, Korea) and Kyung Soon Choi (Sahmyook University,

Korea)

Liaison Officer: Jin Seok Jung (Dong-A Pharmaceutical, Korea)

Organized by

The Organizing Committee of the 20th International Taurine Meeting

Table of Contents

1. Program ---------------------------------------------------------------------

2. Oral Presentation -------------------------------------------------------------

Plenary lecture ---------------------------------------------------------

Session I: Taurine Deficiency in KO mice of Taurine Metabolic Genes

Session II Taurine and Brain Health I ------------------------

Session III Effects of Taurine on Various Organs -----------------

Session IV Biology and Chemistry of Taurine Derivatives I --------

Session V Biology and Chemistry of Taurine Derivatives II -----

Session VI Taurine and Brain Health II --------------------------

Session VII Taurine and Brain Health III ---------------------------

Session VIII Effects of Taurine on Obesity, Diabetes and Nutrition------

Session IX Taurine for Energy Production and Muscle --------------

Session X Taurine and Brain Health IV -----------------------------

Session XI Taurine and Brain Health V ------------------------------

3. Poster Presentation

Session I -----------------------------------------------------------------

Session II ----------------------------------------------------------------

4. Abstracts ------------------------------------------------------------------

Oral Abstracts ----------------------------------------------------------------

Poster Abstracts --------------------------------------------------------------

5. Guidelines for “Full Paper” submission --------------------------------

6. Author Index--------------------------------------------------------------

Program

May 23

(Mon)

May 24

(Tue)

May 25

(Wed)

May 26

(Thu)

May 27

(Fri)

May 28

(Sat)

09:00~12:00

Opening ceremony,Session I

(22F Ruby H)

Session IV,Session V(22F Ruby

H)

Session VIII,Session IX,

(22F Ruby H)

Session X,Session XI(4F Maple

H)

Optional Tour

Palaces DMZ Castles

12:00~14:00 Lunch Buffet

(Seoul Tower)

Lunch Buffet

(2F Seven Square)

Lunch Buffet (4F Maple H) Lunch

Buffet(4F Maple

H)Poster Standing Dong-A Socio

Holdings Research Institute

&Suwon

Hwaseong(UNESCO)

14:00~18:00

Session II,Session III

(22F Ruby H)Session VI,Session VII(22F Ruby

H)Seoul

CityTourPoster

Standing

18:00~21:00

Registration/ Cocktail

party with light meal

(22F Opal R)

Palace Tour/ Welcome

Dinner(22F Ruby H)

20th

Anniversary(22F

Diamond H)

Farewell Party(Chavit Cuisine)

09:00~18:00

Poster I(22F Opal R)

Standing: 17:15~18:00

Poster II(22F Opal

R)

Standing: 13:10~13:5

0

*Special free tour (Tong-Tong Tour, am 10:30 – 11:30, May 25, Wed.) to new Seoul City Hall with English guide for accompanying persons in Taurine Meeting. No reservation is required and tour starts at am 10:15 at 1st floor of Plaza Hotel.

Monday, May 23

18:00 - 21:00 Registration (Opal Room, 22F, Plaza Hotel)

18:00 - 21:00 Cocktail Reception at Opal Room

Tuesday, May 24

9:00 - 12:00/15:00 - 18:00 Registration

9:00 - 9:20 Opening Ceremony

9:20 - 11:15 Session I

Taurine Deficiency in Knockout Mice of Taurine Metabolic Genes

Chairperson: Eunkyue Park (NYS Institute for Basic Research in DD, USA) & Byong Kak Kim (Seoul National University, Korea)

9:20 - 10:10 Plenary Lecture

Regulation of hepatic gene expression in response to taurine depletion: observations in the Cdo1-null mouse

Martha H. Stipanuk, Halina Jurkowska, Julie Niewiadomski, Lawrence L. Hirschberger, Heather B. Roman, and Martha H. Stipanuk

Division of Nutritional Sciences, Cornell University, Ithaca, NY, 14853, USA

10:10 - 10:50 Lecture 1

A novel cysteine sulfinic acid decarboxylase knock-out mouse: Taurine distribution in various tissues with and without taurine supplementation

Eunkyue Park 1 , Seung Yong Park2, In Soo Cho3, Bo Sook Kim4 and Georgia Schuller-Levis1

1Department of Developmental Neurobiology, NYS Institute for Basic Research in Developmental Disabilities, Staten Island, NY, United States

2School of Veterinary Medicine, Konkuk University, Seoul, Korea, 3Department of Virology,

National Veterinary Research and Quarantine Service, Anyang, Korea, 4Grand Seoul Zoo, Guachun, Korea.

10:50 - 11:15 Oral Presentation 1

Glucose homeostasis and retinal histopathology in CSAD KO mice

Francoise Sidime 1 , Greg Phillips2, Nicole Lamassa1, Eunkyue Park2,Dinali Obeysekera1 and Abdeslem El Idrissi1

1College of Staten Island of the City University of New York, United States; 2New York State Institute for Basic ResearchResearch in Developmental Disabilities, Staten Island, NY, United States

11:30 – 14:00 Lunch at Seoul Tower Restaurant

14:30 - 15:30 Session II

Taurine and Brain Health I

Chairperson: Abdeslem El Idrissi (The College of Staten Island CUNY, USA) & Young Sook Kang (Sookmyung Women’s University, Korea)

14:30 – 15:05 Lecture 2

Neuroprotection through ER stress inhibition by taurine and taurine combination therapies in a rodent model of stroke

Jang-Yen Wu, Payam M. Gharibani, Rui Tao, Zhiyuan Ma, Anamaria Alexandrescu, Rafaella Genova, Po-Chih Chen, Jigar Modi, Janet Menzie, Chunliu Pan and Howard Prentice

Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL 33431, United States

15:05 – 15:30 Oral Presentation 2

Analysis of neuroprotection by taurine and taurine combinations in primary neuronal cultures and in neuronal cell lines exposed to glutamate excitotoxicity and to hypoxia /re-oxygenation

Howard Prentice, Chunliu Pan, Payam M. Gharibani, Rui Tao, Zhiyuan Ma, Allison L. Price, Grace S. Giraldo, Howard M. Retz, Amit Gupta, Po-Chih Chen, Jigar Modi, Janet Menzie and Jang-Yen Wu.

Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL 33431, United States

15:30 – 15:50 Coffee Break

15:50 - 17:15 Session III

Effects of Taurine on Various Organs

Chairperson: Howard Prentice (Florida Atlantic University, USA) & Dong Hee Lee (University of Seoul, Korea)

15:50 – 16:25 Lecture 3

Crucial role of taurine to preserve retinal structure and function

Nicolas Froger 1 , Wahiba Hadj-Saïd1, José-Alain Sahel1, Serge Picaud1

INSERM, U968, Sorbonne Universités, Université Pierre et Marie Curie (Paris-6) and CNRS, UMR 7210, Institut de la Vision, Paris, France


Taurine supplementation ameliorates the adverse effects of perinatal taurine depletion and/or high sugar intake on myocardium and arterial pressure control after cardiac ischemia/reperfusion in adult female rats

Supaporn Kulthinee1,2, Sasipa Rakmanee1, and Sanya Roysommuti1

1Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand 2Department of Community Public Health, Faculty of Science and Technology, Rajabhat Mahasarakham University, Mahasarakham 44000, Thailand


Perinatal taurine exposure alters renal excretory function via estrogen activity in adult female rats

Sanya Roysommuti1 and Wichaporn Lerdweeraphon1,2

1Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.2Faculty of Veterinary Medicine, Mahasarakham University, Mahasarakham 44000, Thailand.

17:15 – 18:00 Poster Session I Standing Time (45 min)

18:00 – 19:00 Taking a walk and pictures at DEOKSUGUNG

19:00 – 21:00 Welcome Dinner at Ruby Hall

Wednesday, May 25

9:00 – 10:25 Session IV

Biology and Chemistry of Taurine Derivatives I

Chairperson: Simo S. Oja (University of Tampere, Finland) & Chaekyun Kim (Inha University, Korea)

9:00 - 9:35 Lecture 4

Opposing effects of taurine and taurine chloramine on the fate of neutrophils in inflammation

Janusz Marcinkiewicz

Chair of Immunology Jagiellonian University Medical College, Kraków, Poland


Effect of N-(D-Ribopyranosyl)taurinesodium salt on differentiation of human preadipocytes and the expression of adipokines through inhibition of the STAT-3 signaling pathway in differentiated human adipocytes

Kyoung Soo Kim¹, Hyung-In Yang², Sung Hoon Kim³

¹East-West Bone and Joint Disease Research Institute, KyoungHee University, Seoul, Korea²Department of Chemistry, Kunkook University, Seoul, Korea


The interaction of hypotaurine and other sulfinates with reactive oxygen and nitrogen species: a survey of scavenger action and mechanisms of reaction

Alessia Baseggio Conrado¹,², Mila D’Angelantonio³, Laura Pecci¹, Mario Fontana¹

¹Dipartimento di Scienze Biochimiche, Sapienza Università di Roma – Roma, Italia²Photobiology Unit, University of Dundee, Ninewells Hospital & Medical School – Dundee, UK³ISOF, CNR, Area della Ricerca di Bologna - Bologna, Italy

10:25 - 10:45 Coffee Break

10:30 – 11:30 Special free tour (Tong-Tong Tour) to new Seoul City Hall with English guide for accompanying persons in Taurine Meeting (Tour stars at 10:15)

10:45 - 12:10 Session V

Biology and Chemistry of Taurine Derivatives II

Chairperson: Janusz Marcinkiewicz (Jagiellonian University, Poland) & Young Nam Cha (Inha University, Korea)

10:45 - 11:20 Lecture 5

Taurine chloramine exerts proresolving effects through Nrf2-mediated heme oxygenase-1 upregulation

Seung Hyeon Kim1,2, Wonki Kim1, Xiancai Zhong1, Ha-Na Lee1, Kyeojin Kim1, Young-Ger Suh1, Chaekyun Kim3, Young-Nam Cha3, Young-Joon Surh1,2

1Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National University, Seoul 151-742 Republic of Korea; 2Cancer Research Institute, Seoul National University, Seoul 110-799, Republic of Korea; 3Department of Pharmacology and Toxicology, College of Medicine, Inha University, Incheon 400-712, Republic of Korea


Taurine chloramine prevents oxidative stress-induced neuronal cell death through Nrf2-mediated heme oxygenase-1 expression in mouse hippocampal HT22 cell line

Sun Hee Cheong¹, Dong-Sung Lee²

¹Department of Marine Bio Food Science, College of Fisheries and Ocean Science, Chonnam National University, Yeosu 550-749, Republic of Korea and ²College of Pharmacy, Chosun University, Dong-gu, Gwangju, 61452, Republic of Korea


A Study of the effect of Taurine on cell proliferation and apoptosis in the human lung cancer cell line A549

Xiali Zhang¹, Shuo Tu², Huifang Wan³, Yanqin Xia², Zhuoqi Liu², Xiaohong Yang², Fusheng Wan²*

¹Department of Laboratory Animal Science and ²Biochemistry and Molecular Biology and ³Medical Experimental Teaching Center, Nanchang University, Nanchang, China

12:10 – 14:00 Lunch at Seven Square (2nd Floor)

13:10 –13:50 Poster Session II Standing Time (40 min)

14:00 - 15:35 Session VI

Taurine and Brain Health II

Chairperson: Werner Kilb (University Medical Center Mainz, Germany) & Eun Bang Lee (Seoul National University, Korea)

14:00 - 14:35 Lecture 6

Properties of taurine transport in slices from the adult and developing mouse brain

Simo S. Oja¹, O. Sakari Oja², Pirjo Saransaari¹

¹Tampere University Medical School,²Evince Ldt, Tampere, Finland

14:35 - 15:10 Lecture 7

Effects of taurine supplementation on brain excitability and glucose homeostasis

Abdeslem El Idrissi and Francoise Sidime

College of Staten Island of the City University of New York, United States


Protection of taurine against impairment in learning and memory in mice exposed to arsenic

Huai Guan 1 , Shuangyue Li2, Cong Zhang3, Shang Zhou4, Fengyuan Piao2*

1Department of Health Administration, Dalian Medical University, Dalian, Liaoning 116044, P. R. China2Department of Occupational and Environmental Health, Dalian Medical University, Dalian, Liaoning 116044, P. R. China;

3Department of Nutritionand Food Safety, Dalian Medical University, Dalian, Liaoning 116044, China


15:55 - 17:30 Session VII

Taurine and Brain Health III

Chairperson Nicolas Froger (INSERM, France) & Mi Ja Choi (Keimyung University, Korea)

15:55 – 16:30 Lecture 8

Possible role of taurine as excitatory neurotransmitter during perinatal cortical development

Werner Kilb

Institute of Physiology, University Medical Center Mainz, Duesbergweg 6, D-55128 Mainz, Germany


Taurine and its derivative reverse pathology and symptoms of Alzheimer's disease

Young Soo Kim¹·²·*, Hye Yun Kim¹·³, Kyo Seon Hwang¹, Hyunjin Vincent Kim¹·², Seon Young Choi¹, C. Justin Lee¹, Sejin Lee¹·², Ji Yoon Kim¹·², Hochung Jang¹·²

¹Brain Science Institute, Korea Institute of Science and Technology, Seoul, Korea; ²Biological Chemistry Program, Korea University of Science and Technology, Daejeon, Korea; ³Research Institute, GoshenBiotech Inc., Namyangju-si, Gyeonggi-do, Korea

16:55 – 17:30 Lecture 9

Obesity and taurine

Shigeru Murakami

Department of Bioscience, Fukui Prefectural University, Fukui, Japan

18:00 – 21:00 Banquet for Celebrating the 20th Anniversary of International Taurine Meeting

(Diamond Hall, 22F)

Thursday, May 26

9:00 - 10:15 Session VIII

Effects of Taurine on Obesity, Diabetes and Nutrition

Chairperson: Stephen Schaffer (University of South Alabama, USA) & Kyung Ja Chang (Inha University, Korea)


Is the lower taurine levels in the white adipose tissue of the obese mice ameliorated by endurance training?

Ohmori H1, Yamamoto D1, Ebina K1, Ishikura K2, Komine S1, Miyazaki T3, Ono T1, Miyakawa S1

1University of Tsukuba, Japan; 2Sojo University, Japan; 3Tokyo Medical University Ibaraki Medical Center, Japan


Taurine intake with magnesium reduces cardiometabolic risks

Yukio Yamori¹, Miki Sagara², Yoshimi Arai³, Hitomi Kobayashi³, Kazumi Kishimoto³, Ikuko Matsuno³, Hideki Mori¹, Mari Mori¹

¹Institute for World Health Development, Mukogawa Women’s University, Nishinomiya, Japan; ²Laboratory of Preventive Nutritional Medicine, Research Institute for Production and Development, Kyoto, Japan; ³Hyogo Prefecture Health Promotion Association, Kobe, Japan


Comparison of toxicity of taurine and GABA in combination with alcohol in 7-day-old mice

Andrey G. Taranukhin¹, Pirjo Saransaari¹, Kalervo Kiianmaa², Teemu Gunnar³ and Simo S. Oja¹

¹Medical School, University of Tampere, Tampere, Finland, ²Department of Alcohol, Drugs and Addiction, National Institute for Health and Welfare, Helsinki, Finland, ³Alcohol and Drug Analytics Unit, National Institute for Health and Welfare, Helsinki, Finland


10:35 - 12:00 Session IX

Taurine for Energy Production and Muscle

Chairperson Shigeru Murakami (Fukui Prefectural University, Japan) & Kyung Soon Choi (Sahmyook University, Korea)

10:35 - 11:10 Lecture 10

The taurine deficient heart is energy deficient

Stephen Schaffer¹, Kayoko Shimada-Takaura¹, Chian Ju Jong¹, Takashi Ito², Kyoko Takahashi³

¹Department of Pharmacology, University of South Alabama College of Medicine, Mobile, AL, USA²School of Pharmacy, Hyogo University of Health Sciences, Kobe, Japan³Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan


The role of N-acetyltaurine on the normalization of energy metabolism balance in the skeletal muscle after endurance exercise

Teruo Miyazaki 1 , YuhoNakamura2, KeiEbina2, TakakiMizushima2, Song-GyuRa3, KeisukeIshikura4, YasushiMatsuzaki1, HajimeOhmori2, Akira Honda1

1Tokyo Medical University Ibaraki Medical Center, Ibaraki, Japan, 2University of Tsukuba, Tsukuba, Ibaraki, Japan, 3Fukuoka University, Fukuoka, Japan, and 4Sojo University, Kumamoto, Japan.


The effect of maternal taurine supplementation on gestational protein restriction in newborn skeletal muscle in Wistar rats

Lea Hüche Larsen, Sofie Sandø-Pedersen, Laura Kofoed Hvidsten Ørstrup, Niels Grunnet, Bjørn Quistorff and Ole Hartvig Mortensen

Department of Biomedical Sciences, University of Copenhagen, Denmark

12:00 – 13:00 Lunch at Maple Hall

13:00 – 17:30 Dong-A Socio Holdings &Suwon Hwaseong

Visiting Dong-A Socio Holdings Research Institute (1 hr)

Tour in Suwon: Suwon Hwaseong (UNESCO Culture, 40 min)

17:30 – 20:00 Farewell Party at Han River Restaurant (Chavit Cuisine)

Friday, May 27 (Maple Hall, 4F)

9:00 - 10:00 Session X

Taurine and Brain Health IV

Chairperson: Eunkyue Park (NYS Institute for Basic Research in DD, USA) & Sung Hoon Kim (Konkuk University, Korea)

9:00 – 9:35 Lecture 11

Ethanol, taurine and dopamine – a rewarding relationship

Mia Ericson, Lisa Ulenius, Louise Adermark, Bo Söderpalm

Addiction Biology Unit, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy, University of Gothenburg, Sweden


Antenatal taurine improves neural axon development in featl rats with intrauterine growth restriction by inhibiting the activity of Rho-ROCK signaling pathway

Jing Liu, Zu-Lin Lu, Wei Fu

Department of Neonatology & NICU of Bayi Children’s Hospital, Beijing Military General Hospital. Beijing 100700, China


10:20 - 12:25 Session XI

Taurine and Brain Health V

Chairperson: Mia Ericson (University of Gothenburg, Sweden) & KyoungSoo Kim (Kyung Hee University Hospital, Korea)

10:20 – 10:55 Lecture 12

Taurine as a treatment in neurodegenerative diseases and other neurological disorders

Annette K Offringa-Hup

Vitamine B12 Institute NL, Westervoort, The Netherlands


GABAA receptor activation by maternally-derived taurine underlies the temporal regulation of cellular properties of the neural stem cells in the mouse developing cortex

Shiro Tochitani1,2,3,4,5, Tomonori Furukawa6,7, Ryo Bando4,5, Shigeaki Kondo4,5, Takashi Ito8, Yoshitaka Matsushima9, Toshio Kojima10, Hideo Matsuzaki1,2,3, Atsuo Fukuda6

1Division of Development of Mental Functions, Research Center for Child Mental Development, University of Fukui, Fukui 910-1193, Japan; 2Division of Developmental Higher Brain Functions, United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University and University of Fukui, Osaka 565-0871, Japan; 3Research and Education Program for Life Science, University of Fukui, Fukui910-8507, Japan; 4Department of Anatomy and Developmental Neurobiology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima770-8503, Japan; 5Student Lab, The University of Tokushima Faculty of Medicine, Tokushima770-8503, Japan; 6Department of Neurophysiology, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan; 7Department of Neurophysiology, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan; 8SchoolofPharmacy, Hyogo University of Health Sciences, Kobe 650-8530, Japan; 9Department of Applied Biology and Chemistry, Tokyo University of Agriculture, Tokyo156-8502, Japan; 10Health Care Center, Toyohashi University of Technology, Toyohashi 441-8580, Japan


Taurine recovery of learning deficits induced by developmental Pb2+ exposure

Lorenz S. Neuwirth1-6, Nicholas P. Volpe4-5, Chuyon Corwin4-6, Simon Ng3, Navita Madan3, Alyssa M. Ferraro3, Yevgeniy Furman3 and Abdeslem El Idrissi4-6

1Department of Psychology, SUNY Old Westbury, NY, USA2SUNY Neuroscience Research Institute, SUNY Old Westbury, NY, USA3DepartmentofPsychology, The College of Staten Island CUNY, NY, USA4DepartmentofBiology, The College of Staten Island CUNY, NY, USA5The Center for Developmental Neuroscience, The College of Staten Island CUNY, NY, USA6Department of Biology The CUNY Graduate Center, NY, USA

11:45– 12:05 Closing Remarks by Stephen Schaffer (University of South Alabama, USA)

12:05 – 12:25 Announcement for Next International Taurine Meeting

Dr. Fengyuan Piao (Dalian Medical University, China)

Dr. Jianmin Hu (Shenyang Agricultural University, China)

12:25 – 14:00 Lunch at Maple Hall

14:00 – 18:00 Seoul City Tour (Gyeongbokgung, Folklore Museum, Bukchon Hanok Village and Insa-dong street for foreigners)

18:00 – 20:00 Dinner at Korean Restaurant (Kejeol Babsang Restaurant at Insa-dong)

Poster Session IMay 24, Tuesday (09:00-18:00)

*Standing Time: 17:15 – 18:00

P1-1 Taurine protection effort on cisplatin-induced nephrotoxicity by decreasing oxidative DNA

damage and inflammation: an immunocytochemical study

Masahiro Tsunekawa1, Shumin Wang1, Toshihiro Kato2, Takenori Yamashita3, Ning Ma1

1Faculty of Nursing Science, Suzuka University of Medical Science, Suzuka 513-8670, Mie, Japan2Sport Medical Center, Suzukakaisei Hospital, Suzuka 513-0836, Mie, Japan3Faculty of Health Science, Suzuka University of Medical Science, Suzuka 510-0293, Mie, Japan

P1-2 Effects of taurine on Down syndrome model of Caenorhabditis elegans

Youn Jung Ko¹, Dong Hee Lee²

Department of Life Science, University of Seoul, 163 Siripdaegil, Dongdaemun-Gu, Seoul, Korea

P1-3 Perinatal taurine supplementation alters renal function via renin-angiotensin system overactivity

in adult female rats

Sanya Roysommuti¹ and Wichaporn Lerdweeraphon¹,²

¹Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002,

Thailand.

²Faculty of Veterinary Medicine, Mahasarakham University, Mahasarakham 44000, Thailand.

P1-4 Taurine supplementation improves sugar-increased renal sympathetic nerve activity related to

renin release in adult male rats

Sasipa Rakmanee¹, Supaporn Kulthinee¹,², and Sanya Roysommuti¹

¹Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002,

Thailand

²Department of Community Public Health, Faculty of Science and Technology, Rajabhat

Mahasarakham University, Mahasarakarm 44000, Thailand

P1-5 Taurine Attenuates Epithelial-Mesenchymal Transition-related Genes in Human Prostate Cancer

Cells

Yujiao Tang¹,², Eun-Ju Choi³, Young Joung Hwang4, Pyo-Jam Park5, Sang-Ho Moon¹,², Eun-Kyung

Kim¹,²,*

¹Division of Food Bio Science and ²Korea Nokyong Research Center, Konkuk University, Chungju,

Korea;

³Division of Sport Science, Konkuk University, Chungju, Korea;4Department of Food Science & Culinary, International University of Korea, Jinju, Korea;5Department of Biotechnology, Konkuk University, Chungju, Korea

P1-6 Inhibitory Effects of Taurine on Migration in Human Lung Cancer Cells

Yujiao Tang¹,², Eun-Ju Choi³, Pyo-Jam Park⁴, Sang-Ho Moon¹,², Eun-Kyung Kim¹,²*


Korea

³Division of Sport Science, Konkuk University, Chungju, Korea4Department of Biotechnology, Konkuk University, Chungju, Korea

P1-7 The Effect of Radiation on the Expression of Taurine Transporter in Mouse

Takenori Yamashita1, Toshihiro Kato1,2, Masahiro Tunekawa1, Yeunhwa Gu3, Ning Ma1

1Faculty of Health Science, Suzuka University of Medical Science, Kishioka, Suzuka, Mie, 510-

0293, Japan.2Sport Medical Center, Suzukakaisei Hospital, Koucho, Suzuka, Mie, 513-0836, Japan.3Faculty of Health Seience, Junshin Gakuen University, Chikushigaoka, Minamiku, Fukuoka, 815-

8510, Japan.

P1-8 Investigation of the role of a supplementation with taurine on the effects of hypoglycemic-

hypotensive therapy against diabetes-induced nephropathy in rats

Kashyap Pandya, Cesar A. Lau-Cam

Department of Pharmaceutical Sciences, St. John’s University, College of Pharmacy and Health

Sciences, Jamaica, New York 11439, USA

P1-9 The effect of metformin and taurine, alone and in combination, on the oxidative stress caused

by diabetes in the brain of rats

George J. Clark, Kashyap Pandya,Cesar A. Lau-Cam

Department of Pharmaceutical Sciences, St. John’s University, College of Pharmacy and Health

Sciences, Jamaica, New York 11439, USA

P1-10 The effect of taurine and its immediate homologs on diabetes-induced oxidative stress in the

brain and spinal cord of rats

Sanket N. Patel, Cesar A. Lau-Cam

Department of Pharmaceutical Sciences, St. John's University, College of Pharmacy and Health

Professions, Jamaica, New York 11439, USA

P1-11 Taurine inhibits the activation of Kupffer cells induced by Lipopolysaccharide in Alcoholic

liver damaged rats

Gaofeng Wu, Riyi Tang, Jiancheng Yang, Yang Yu, Shumei Lin, Qunhui Yang, Qiufeng Lv, Jianmin

Hu*

College of Animal Science & Veterinary, Shenyang Agricultural University, Shenyang, China

P1-12 Taurine inhibits oxidative stress and apoptosis of hepatocytes induced by alcohol in rats

Riyi Tang, Gaofeng Wu , Wenying Jing, Jiancheng Yang, Shumei Lin, Qunhui Yang, Qiufeng Lv,

Jianmin Hu*


P1-13 Effect of taurine supplement on metabolomics profiling of dyslipidemia in high-fat diet

induced-rat model by ¹H-NMR MS spectroscopy

Kyoung Soo Kim¹,Hyung-In Yang¹, Eun Jung Bang²1East-West Bone and Joint Disease research Institute, Kyung Hee University Hospital at Gangdong,

Seoul, Republic of Korea2Integrated Metabolomics Research Group, Western Seoul Center, Korea Basic Science Institute,

Seoul, Republic of Korea.

P1-14 Antioxidant effects of short-neck clam (Tapes philippinarum) water extract containing taurine

against AAPH-induced oxidative stress in zebrafish embryos

Dong-Sung Lee¹, Ki Han Kwon², Sun Hee Cheong³

¹College of Pharmacy, Chosun University, Dong-gu, Gwangju, 61452, Republic of Korea;

²Department of Food Science and Nutrition, College of Health, Welfare, and Education, Gwangju

University, Gwangju 61743, South Korea and ³Department of Marine Bio Food Science, College of

Fisheries and Ocean Science, Chonnam National University, Yeosu 550-749, Republic of Korea

P1-15 Mussel (Mytilus coruscus) water extract containing taurine prevents LPS-induced

inflammatory responses in zebrafish model

Sun Hee Cheong¹, Ki Woong Kim¹, Ki Han Kwon², Dong-Sung Lee³

¹Department of Marine Bio Food Science, College of Fisheries and Ocean Science, Chonnam

National University, Yeosu 550-749, Republic of Korea; ²Department of Food Science and Nutrition,

College of Health, Welfare, and Education, Gwangju University, Gwangju 61743, South Korea and

³College of Pharmacy, Chosun University, Dong-gu, Gwangju, 61452, Republic of Korea

P1-16 Taurine provides neuroprotection against oxidative stress-induced mouse hippocampal HT22

cell damage through the Nrf2 and MAPK pathways

Dong-Sung Lee¹, Sun Hee Cheong²

¹College of Pharmacy, Chosun University, Dong-gu, Gwangju, 61452, Republic of Korea and

²Department of Marine Bio Food Science, College of Fisheries and Ocean Science, Chonnam

National University, Yeosu 550-749, Republic of Korea

P1-17 Taurine chloramine inhibits lipopolysaccharide-induced neuroinflammatory responses through

Nrf2-mediated heme oxygenase-1 expression in mouse BV2 microglia cells

Dong-Sung Lee¹, Ki Woong Kim², Sun Hee Cheong²

¹College of Pharmacy, Chosun University, Dong-gu, Gwangju, 61452, Republic of Korea and

²Department of Marine Bio Food Science, College of Fisheries and Ocean Science, Chonnam

National University, Yeosu 550-749, Republic of Korea

P1-18 Effects of Taurine on Endurance Capacity and Physical Fatigue in Trained Mice

Eun-Kyung Kim¹,², Yujiao Tang¹,², Young-Jin Choi¹, Eun-Ju Choi³


Korea

³Division of Sport Science, Konkuk University, Chungju, Korea

P1-19 Antioxidative Effects of Taurine on Hepatic System and Muscle Fatigue after High Intensity

Workout in Mice

Eun-Kyung Kim¹,², Yujiao Tang¹,², Young-Jin Choi¹, Eun-Ju Choi³


Korea

³Division of Sport Science, Konkuk University, Chungju, Korea

P1-20 Effect of taurine on iNOS-mediated DNA damage in drug-induced renal injury

Toshihiro Kato1, Masahiro Tsunekawa2, Shumin Wang2, Takenori Yamashita3, Ning Ma2

1Sport Medical Center, Suzukakaisei Hospital, Suzuka 513-0836, Mie, Japan2Faculty of Nursing Science, Suzuka University of Medical Science, Suzuka 513-8670, Mie, Japan3Faculty of Health Science, Suzuka University of Medical Science, Suzuka 510-0293, Mie, Japan

P1-21 Effects of taurine on spermioteleosis in rats

Jiancheng Yang, Gaofeng Wu, Shu zhang, Qiufeng Lv, Shumei Lin and Jianmin Hu

College of Animal Science & Veterinary Medicine, University of Shenyang Agricultural University,

Shenyang, Liaoning Province, P.R.China

P1-22 Effects of taurine on hyperuricemic rats with kidney injury

Ying Feng, Jiancheng Yang, Yongchao Gao, Gaofeng Wu, Shumei Lin，Jianmin Hu

College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang

110866, P.R.China

P1-23 Effects of taurine on spermatogenesis in rats

Jiancheng Yang, Gaofeng Wu, Meng zhang, Qiufeng Lv, Shumei Lin and Jianmin Hu

College of Animal Science & Veterinary Medicine, University of Shenyang Agricultural University,

Shenyang, Liaoning Province, P.R.China

P1-24 Is Taurine a Biomarker in Autism?

Eunkyue Park1, Ira Cohen2, Maripaz Gonzalez2, Mario Castellano3, Michael Flory4, Edmund C.

Jenkins5, W. Ted Brown5, and Georgia Schuller-Levis1

Departments of Developmental Neurobiology1, Psychology2, Infant Development4, and Human

Genetics5, NY State Institute for Basic Research in Developmental Disabilities, Staten Island NY

10314, United States, 3Division of Hematology/Oncology, Department of Medicine, Staten Island

University Hospital, Staten Island, NY 10305, United States

P1-25 Taurine normalizes the essential trace elements levels in mouse liver and kidney subchronic

exposure to arsenic

Cong Zhang1, Shuangyue Li2, Fengyuan Piao2

1Department of Nutrition and Food Safety, Dalian Medical University, PR China2Department of Occupational and Environmental of Health, Dalian Medical University, PR China

P1-26 Taurine content in Japanese seaweed

Azusa Kawasaki¹, Ayuko Ono¹, Shoshi Mizuta², Mitsunobu Kamiya², Shigeru Murakami¹

¹Department of Bioscience, Fukui Prefectural University, Fukui, Japan

²Department of Marine Bioscience, Fukui Prefectural University, Obama, Japan

P1-27 Taurine reduced the duration of AF induced by CaCl2- Ach in rats through inhibiting the atrial

electrical remodeling

Qunhui Yang , Man Feng, Jiancheng Yang, Gaofeng Wu, Ying Feng, Qiufeng Lu, Shumei Lin,

Jianmin Hu

College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang,

China

P1-28 A Study on Blood Lipid and Leptin Change of a White Rat in a High-fat Diet with Taurine

10%

Kyung-Soon Choi¹, Kyung-Ok Shin²

¹²Dept. of Food and Nutrition, Sahmyook University, Seoul 01795, Korea

P1-29 The effect on blood lipid concentration and liver-function improvement of a white rat in a

high-fat diet with taurine 20%

Kyung-Soon Choi¹, Kyung-Ok Shin1, Ha Won Kim2

¹Dept. of Food and Nutrition, Sahmyook University, Seoul 01795, Korea; ²Dept. of Life Science,

University of Seoul, Seoul 02504, Korea

P1-30 Taurine supplementation in perinatal period on maternal diabetes mellitus prevents

development of diabetes mellitus (DM) and hypertension in the offspring during adulthood.

Punyaphat Teangphuck1, Rungrudee Srisawat1, Sanya Roysommuti2, Atcharaporn Thaeomor1

1School of Preclinic, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima,

30000, Thailand.2Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon

Kaen, 40000, Thailand

P1-31 Sex dependent effects of taurine supplementation in maternal diabetic mellitus on

developments diabetic mellitus and hypertension in adult offspring

Atcharaporn Thaeomor1, Janeyuth Chaisakul2, Suphaket Seanthaweesuk3, Nuntiya Somparn3, Sanya

Roysommutti4


30000, Thailand.2Department of Pharmacology, Phramongkutklao College of Medicine, Bangkok,

10400, Thailand.3Department of Preclinic Science, Faculty of Medicine, Thammasat University,

Rangsit Campus, Khlong Luang, Pathum Thani, 12120, Thailand. 4Department of Physiology,

Faculty of Medicine, Khon Kaen University, Khon Kaen, 40000, Thailand

.

P1-32 Effects of taurine supplementation in perinatal period on maternal obesity prevent

development of metabolic disorder in adult male rats offspring.

Chonticha Tangnoi1, Sajeera Kupittayanant1, Sanya Roysommuti2, Atcharaporn Thaeomor1


30000, Thailand.2Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon

Kaen, 40000, Thailand.

P1-33 Taurine normalizes the levels of Se, Cu, Fe in mouse liver and kidney exposed to arsenic

subchronically

Cong Zhang1 Shuangyue Li2 Fengyuan Piao2

1Department of Nutrition and Food Safety, Dalian Medical University, PR China2Department of Occupational and Environmental of Health, Dalian Medical University, P.R. China

P1-34 Effects of replacement of methionine in diets with different levels of taurine on the growth

performance and Blood index of Broilers

Qiufeng Lv, Ling Sun, Yiqing Cui, Gaofeng Wu, Jiancheng Yang, Shumei Lin, Qunhui Yang, Lin

Mei, Jianmin Hu*


P1-35 Effects of taurine on gene and protein expressions of ACE, ACE2 and HSP70 of hypothalamic

pitutitary adrenal (HPA) of stress-induced hypertensive rats

Qiufeng Lv, Ling Sun, Yiqing Cui, Gaofeng Wu, Jiancheng Yang, Shumei Lin, Feng Ying, Qunhui

Yang, Lin Mei, Jianmin Hu*


P1-36 The effect of taurine on follicle and oocyte development of rats in vitro

Teng Mu1, Jiancheng Yang2, Gaofeng Wu2,Ying Feng2and Jianmin Hu3

1Academy of Life Sciences,Liaoning University, Shenyang, P.R. China2College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang,

P.R. China 3College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang,

P.R. China

P1-37 Comparative analysis of microbicidal and anti-inflammatory properties of novel taurine

bromamine derivatives and bromamine T

Walczewska M¹, Peruń A¹, Białecka A², Sróttek M¹, Jamróz W³ Dorożyński P³, Jachowicz R³.

Kulinowski P⁴, Nagl M5, Gottardi W5. , Marcinkiewicz J¹

¹Department of Immunology, Jagiellonian University Medical College Krakow, Poland

²Center of Microbiological research and Autovaccines Ltd. Krakow, Poland

³Department of Pharmaceutical Technology and Biopharmaceutics, Jagiellonian University, Medical

College, Faculty of Pharmacy, Krakow, Poland4Institute of Technology, The Pedagogical University of Cracow, Kraków, Poland5Department of Hygiene, Microbiology and Social Medicine, Division of Hygiene and Medical

Microbiology, Medical University of Innsbruck, Innsbruck, Austria

P1-38 Distributions of cone and retinal ganglion cell losses in in a mouse model of induced taurine

depletion

Hadj-Said Wahiba1,; García-Ayuso Diego2, Froger Nicolas1; Ivkovic Ivana1 ; Jiménez-López Manuel2

; Dubus Élisabeth1 ; Dégardin-Chicaud Julie1 ; Simonutti Manuel1 ; César Quénol1 ; Neveux

Nathalie3,4 ; Vidal-Sanz Manuel2; Sahel Jose A.1,4; Picaud Serge1

1Centre de recherche Institut de la Vision UMR S 968 INSERM / CHNO des Quinze-Vingts, Paris,

France;² Departamento de Oftalmología, Facultad de Medicina, Universidad de Murcia and Instituto

Murciano de Investigación Biosanitaria- Hospital Virgen de la Arrixaca (IMIB-Arrixaca), Murcia,

Spain;3Service de Biochimie, Groupe Hospitalier Cochin – Hôtel-Dieu, Assistance Publique – Hôpitaux de

Paris, Paris, France;4Centre Hospitalier National d’Ophtalmologie des Quinze-Vingts, Paris, France.

P1-39 A novel cysteine sulfinic acid decarboxylase knockout mouse: Immune function II

Eunkyue Park1, Seung Yong Park2, In Soo Cho3, Bo Sook Kim4 and Georgia Schuller-Levis1 1Department of Developmental Neurobiology, NYS Institute for Basic Research in Developmental

Disabilities, Staten Island, NY, United States, 2School of Veterinary Medicine, Konkuk University,

Seoul, Korea, 3Department of Virology, National Veterinary Research and Quarantine Service,

Anyang, Korea, 4 Grand Seoul Zoo, Guachun, Korea

P1-40 Taurine alleviate hexabromocyclododecane-induced cytotoxicity in PC12 cells via inhibiting

oxidative stress

Lu liu1, Ning fan1, Yan li1, Xiuli zhang2, Yachen Li3

1College of Basic Medical Sciences, Dalian Medical University, Dalian, Liaoning 116044, China.2School of Pharmaceutical Sciences, Binzhou Medical University, Yantai, Shandong 264003, China3Department of Occupational and Environmental Health, Dalian Medical University, Dalian,

Liaoning 116044, China

P1-41 Neuroprotective effect of taurine-rich cuttlefish (Sepia officinalis) extract against hydrogen

peroxide-induced oxidative stress in SH-SY5Y cells

Yon-Suk Kim, Jin-Woo Hwang, Bo-Im Ryu, Nam-Joo Jeon, Jae-Woong Lee, Xin Dong, Sithranga

Boopathy Natarajan, Pyo-Jam Park

Department of Biotechnology, Konkuk University, Chungju, Korea

P1-42 Neuroprotection by taurine on HBCD-induced apoptosis in PC12 cells

Xiuli zhang1, Shuangyue li2, Xiaohui Liu2, Jing Shao2, Fengyuan Piao2, Yachen Li2 1School of Pharmaceutical Sciences, Binzhou Medical University, Yantai, Shandong, 264003, China2Department of Occupational and Environmental Health, Dalian Medical University, Dalian,

Liaoning, 116044, China

P1-43 Fermented Asterina pectinifera with Cordyceps militaris mycelia induced apoptosis in B16F10

melanoma cells

Yon-Suk Kim, Jin-Woo Hwang, Bo-Im Ryu, Nam-Joo Jeon, Jae-Woong Lee, Xin Dong, Sithranga

Boopathy Natarajan, Pyo-Jam Park


P1-44 Taurine attenuates doxorubicin-induced toxicity in B16F10 cells

Yon-Suk Kim, Jin-Woo Hwang, Bo-Im Ryu, Nam-Joo Jeon, Xin Dong, Jae-Woong Lee, Weligala

Pahalagedara Amila Srilal Nawarathna, Sithranga Boopathy Natarajan, Pyo-Jam Park


Poster Session IIMay 25, Wednesday (9:00-18:00)

*Standing Time: 13:10-13:50

P2-1 Taurine ameliorates arsenic-induced apoptosis in the hippocampus of mice through intrinsic

pathway

Shuangyue Li1, Lijun Yang2, Yan Zhang1, Cong Zhang1, Jing Shao1, Xiaohui Liu1, Yachen Li1,

Fengyuan Piao 1*1Department of Occupational and Environmental Health, Dalian Medical University, Dalian Liaoning

116044, China2Dalian Center for Disease Control and Prevention, Dalian Liaoning 116044, China

P2-2 Protection of taurine against PFOS-induced neurotoxicity in PC12 cells

Xiaohui Liu1, Chunna Li1, Qi Liu1, Shuangyue Li1, Yachen Li1, Jing Shao1,*, Hong Hu2,*1Department of Environmental Health and Toxicology, School of Public Health, Dalian Medical

University, Dalian 116044, China2Laboratory medicine The Second Affiliated Hospital of Dalian Medical University, Dalian 116027,

China

P2-3 Taurine protects mouse cerebellum against As2O3-induced autophagy

Fengyuan Piao1, Yan Zhang1, Lijun Yang2, Cong Zhang, Jing Shao, Xiaohui Liu, Yachen Li,

Shuangyue Li1*1Department of Occupational and Environmental Health, Dalian Medical University, Dalian Liaoning

116044, China2Dalian Center for Disease Control and Prevention, Dalian Liaoning 116044, China

P2-4 Role of taurine in BDE 209-induced oxidative stress in PC12 cells

Jing Shao1, Qi Liu1, Chunna Li1, Yachen Li1, Shuangyue Li1, Xiaohui Liu1,*, Hong Hu2,*1Department of Environmental Health and Toxicology, School of Public Health, Dalian Medical

University, Dalian 116044, China2Laboratory medicine The Second Affiliated Hospital of Dalian Medical University, Dalian 116027,

China

P2-5 Protection of Taurine against Arsenic-Induced DNA Damage of Mice Kidneys

Donghua Zheng1, Hongxin Qu2, Shuangyue Li2, Cong Zhang3, Fengyuan PIAO2*1Nursing Department, the Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning

116044, China2Department of Occupational and Environmental Health, Dalian Medical University, Dalian,

Liaoning 116044, China3Department of Nutrition and Food Safety, Dalian Medical University, Dalian, Liaoning 116044,

China

P2-6 Taurine improved lipid metabolism and enhanced the sensitivity of liver to insulin.

Shumei Lin1, Jiancheng Yang2, Mei Liu3, Gaofeng Wu4, Qiufeng Lv5, Ying Feng6, Qunhui Yang7, and

Jianmin Hu8

College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang,

China

P2-7 Regional differences in ethanol-induced taurine elevation in the rat nucleus accumbens and

dorsal striatum

Lisa Ulenius1, Louise Adermark1, Bo Söderpalm1,2, Mia Ericson1

1Institute of Neuroscience and Physiology, Section of Psychiatry and Neurochemistry, The

Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden2Beroendekliniken, Sahlgrenska University Hospital, Gothenburg, Sweden

P2-8 Sex dependent effects of taurine supplementation in maternal diabetic mellitus on prevents

development diabetic mellitus and hypertension in adult offspring

Atcharaporn Thaeomor1, Janeyuth Chaisakul2, Suphaket Seanthaweesuk3, Nuntiya Somparn3, Sanya

Roysommutti4


30000, Thailand.2Department of Pharmacology, Phramongkutklao College of Medicine, Bangkok,

10400, Thailand.3Department of Preclinic Science, Faculty of Medicine, Thammasat University,

Rangsit Campus, Khlong Luang, Pathum Thani, 12120, Thailand. 4Department of Physiology,

Faculty of Medicine, Khon Kaen University, Khon Kaen, 40000, Thailand

P2-9 Antioxidant effect of taurine-rich Paroctopus dofleini extracts through inhibiting ROS

production against LPS-induced oxidative stress in vitro and in vivo model

Nam-Joo Jeon, Yon-Suk Kim, Jin-Woo Hwang, Bo-Im Ryu, Jae-Woong Lee, Xin Dong, Weligala

Pahalagedara Amila Srilal Nawarathna, Sithranga Boopathy Natarajan, Pyo-Jam Park


P2-10 Antioxidant Activity of Fenneropenaeus chinensis Heads

Bo-Im Ryu, Dong Xin, Nam-Joo Jeon, Sithranga Boopathy Natarajan, Yon-Suk Kim Pyo-Jam Park

Department of Biotechnology, Konkuk University, Chungju 380-701, Korea

P2-11 Taurine chloramine exerts antifungal effects through upregulation of dectin-1 mediated by

heme oxygenase-1-derived carbon monoxide

Seung Hyeon Kim1,4, Xiancai Zhong1, Wonki Kim1, Kyeojin Kim1, Young-Ger Suh1, Chaekyun

Kim2,Young-Nam Cha2, Young-Joon Surh1,3,4

1Tumor Microenvironment Global Core Research Center, College of Pharmacy, Seoul National

University, Seoul 151-742 Republic of Korea2Department of Pharmacology and Toxicology, College of Medicine, Inha University, Incheon 400-

712, Republic of Korea 3Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of

Convergence Science, Seoul National University, Seoul 151-742, Republic of Korea4Cancer Research Institute, Seoul National University, Seoul 110-799, Republic of Korea

P2-12 Taurine Attenuates Salt-sensitive Blood Pressure Rise in a Korean Population

Yukio Yamori¹, Mari Mori¹, Miki Sagara², Fnshi Xu³, Young Hyo Lim³, Bo Youl Choi⁴, Bee Keun

Kim5, Yong Gu Lee5, Mi Kyung Kim⁴, Jinho Shin³,⁴

¹Institute for World Health Development, Mukogawa Women’s University, Nishinomiya, Japan;

²Laboratory of Preventive Nutritional Medicine, Research Institute for Productive Development,

Kyoto, Japan; ³Department of Internal Medicine, Hanyang University College of Medicine, Seoul,

South Korea; ⁴Department of Preventive Medicine, Hanyang University College of Medicine, Seoul,

South Korea; 5 Division of Cardiology, Department of Internal Medicine, Sung-Ae General Hospital,

Seoul, South Korea

P2-13 A highly sensitive and cheap taurine assay based on E. coli taurine dioxygenase coupled to

papain activation

Ole Hartvig Mortensen¹, Katrine Seide Pedersen¹, Lea Hüche Larsen¹, Ian Henry Lambert², Niels

Grunnet¹, Bjørn Quistorff¹

¹Cellular and Metabolic Research Section, Department of Biomedical Sciences, University of

Copenhagen,Copenhagen, Denmark

²Section of Cellular and Developmental Biology, Department of Biology, University of Copenhagen,

Copenhagen, Denmark

P2-14 Protective effect of taurine on doxorubicin-induced acute kidney injury mice

Eun-Ju Choi¹, Yujiao Tang², Young-Jin Choi², Eun-Kyung Kim²

¹Division of Sport Science, Konkuk University, Chungju, Korea

²Division of Food BioScience, Konkuk University, Chungju, Korea

P2-15 Synthesis of N-chloroamino acids and their effects on NO production in LPS-activated RAW

264.7 cells

Yeong Min Kwon*, Rang Ie Kim, In Soon Kang, Chaekyun Kim

Laboratory of Leukocyte Signaling Research, Department of Pharmacology, Inha University School

of Medicine, Incheon 22212, Korea

P2-16 Taurine chloramine, a taurine metabolite produced from activated neutrophils, inhibits

receptor activator of NFκB ligand-induced osteoclastogenesis through NFATc1

In Soon Kang, Chaekyun Kim

Laboratory of Leukocyte Signaling Research, Department of Pharmacology, Inha University School

of Medicine, Incheon 22212, Korea

P2-17 The effect of taurine supplementation on beta-oxidation in skeletal muscle during prolonged

exercise ~examination using serum acetyl-carnitine~

Mizushima T1, Miyazaki T2, Ebina K1, Ishikura K3, Ono T1; Komine S1, Nakamura Y1, Tokinoya K1,

Yamamoto D1, Honda A2, Matsuzaki S2, Miyakawa S1, Ohmori H1

1University of Tsukuba, Japan, 2Tokyo Medical University Ibaraki Medical Center, Japan, 3Sojo

University, Japan

P2-18 Neuroprotective effect of a taurine-rich seafood, Octopus ocellatus, against LPS-induced

inflammation in neuron cells

Seung Hong Lee¹, Eun A Kim², WonWoo Lee², Soo Yeon Park³, Eui Jeong Han³, Ju Hyung Um³,Sun

Hee Cheong 3,4, Youngheun Jee5, You-Jin Jeon², Ginnae Ahn3,4,*

¹Division of Food Bioscience and Korea Nokyong Research Center, Konkuk University,

Chungju,Republic of Korea

²Department of Marine Life Science, Jeju National University, Jeju, Republic of Korea

³Department of Food Technology and Nutrition, Chonnam National University, Yeosu, Republic of

Korea4Department of Marine Bio-Food Sciences, Chonnam National University, Yeosu, Republic of Korea5College of Veterinary Medicine and Applied Radiological Science Institute, Jeju National

University, Jeju 6, Republic of Korea

P2-19 Hepatoprotective effects of Xylose-Taurine reduced against hydrogen peroxide-induced

oxidative stress in cultured hepatocytes

Soo Yeon Park¹, Kyung Ja Chang², Sung Hoon Kim³, Won Woo Lee4, You-Jin Jeon4, Chang-Bum

Ahn1,5, Sun Hee Cheong1,6,*, and Ginnae Ahn1,6,*

¹Department of Food Technology and Nutrition, Chonnam National University, Yeosu, Korea

²Department of Food and Nutrition, Inha University, Incheon, Korea

³Department of Chemistry, Konkuk University, Seoul, Korea4Department of Marine Life Science, Jeju National University, Jeju, Korea5Division of Food and Nutrition, Chonnam National University, Gwang ju, Korea6Department of Marine Bio-Food Sciences, Chonnam National University, Yeosu, Korea

P2-20 Anti-inflammatory effects of Galactose-Taurine sodium salt in LPS-activated RAW 264.7 cells

Soo Yeon Park¹, Kyung Ja Chang², Sung Hoon Kim³, WonWoo Lee⁴, You-Jin Jeon⁴, Chang-Bum

Ahn1,5, Sun Hee Cheong1,6,*, and Ginnae Ahn1,6,*


²Department of Food and Nutrition, Inha University, Incheon, Korea ³Department of Chemistry,

Konkuk University, Seoul, Korea 4Department of Marine Life Science, Jeju National University,

Jeju, Korea 5Division of Food and Nutrition, Chonnam National University, Gwang ju, Korea 6Department of Marine Bio-Food Sciences, Chonnam National University, Yeosu, Korea

P2-21 Xylose-Taurine reduced suppresses the inflammatory responses in lipopolysaccharide-

stimulated RAW 264.7 macrophages

Chang-Bum Ahn1,2,a, WonWoo Lee3,a, Sun Hee Cheong1,4, Soo Yeon Park¹, Kyung Ja Chang5, Sung

Hoon Kim6, You-Jin Jeon³*, and Ginnae Ahn1,4,*


²Division of Food and Nutrition, Chonnam National University, Gwang ju, Korea

³Department of Marine Life Science, Jeju National University, Jeju, Korea4Department of Marine Bio-Food Sciences, Chonnam National University, Yeosu, Korea5Department of Food and Nutrition, Inha University, Incheon, Korea6Department of Chemistry, Konkuk University, Seoul, Korea

P2-22 Anti-inflammatory effects of Galactose-Taurine sodium salt, a taurine derivate in zebrafish

embryos in vivo model

Eun A Kim1,a, WonWoo Lee1,a, Sun Hee Cheong2,3, Soo Yeon Park³, Kyung Ja Chang4, Sung Hoon

Kim5, You-Jin Jeon1,*, and Ginnae Ahn2,3,*

aThese authors contributed equally to this study.

¹Department of Marine Life Science, Jeju National University, Jeju, Korea

²Department of Marine Bio-Food Sciences, Chonnam National University, Yeosu, Korea

³Department of Food Technology and Nutrition, Chonnam National University, Yeosu, Korea4Department of Food and Nutrition, Inha University, Incheon, Korea5Department of Chemistry, Konkuk University, Seoul, Korea

P2-23 Role of a potential antioxidant, Octopus ocellatus consisted of a plentiful taurine against

damages caused by oxidative stress

WonWoo Lee¹, Changyong Choi², Eun A Kim¹, Eui Jeong Han3,4, Ju Hyung Um3,4, Youngheun Jee5,

You-Jin Jeon¹, Jae-Woon Nah², Seung Hong Lee6, You-Jin Jeon¹* and Ginnae Ahn³,⁴

¹Department of Marine Life Science, Jeju National University, Jeju, Korea

²Department of Polymer Science and Engineering, Sunchon National University

³Department of Marine Bio-Food Sciences and 4Department of Food Technology and Nutrition,

Chonnam National University, Yeosu, Korea5College of Veterinary Medicine and Applied Radiological Science Institute, Jeju National

University, Jeju 690-756, Republic of Korea 6Division of Food Bioscience and Korea Nokyong Research Center, Konkuk University, Chungju,

27478, Republic of Korea

P2-24 Protective effects of Xylose-Taurine reduced against damages caused by oxidative stress in

zebrafish embryos in vivo model

Sun Hee Cheong1,2,a,WonWoo Lee3,a,Eun A Kim³, Kyung Ja Chang4, Sung Hoon Kim5, Soo Yeon

Park², Chang-Bum Ahn2,6, You-Jin Jeonc,*, and Ginnae Ahn 1,2,*

aThese authors contributed equally to this study.

¹Department of Marine Bio-Food Sciences, Chonnam National University, Yeosu, Korea

²Department of Food Technology and Nutrition, Chonnam National University, Yeosu, Korea

³Department of Marine Life Science, Jeju National University, Jeju, Korea4Department of Food and Nutrition, Inha University, Incheon, Korea5Department of Chemistry, Konkuk University, Seoul, Korea6Division of Food and Nutrition, Chonnam National University, Gwang ju, Korea

P2-25 Protective effects of Loliolus beka Gray meet against H2O2-induced oxidative stress in Chang

liver cells and Zebrafish embryo model

Seung Hong Lee1,#, Eui Jeong Han2,#, Eun A Kim4, WonWoo Lee4, Soo Yeon Park²,c, Ju Hyung Um²,³,

Youngheun Jee5, You-Jin Jeon4, Chang-Bum Ahn6, and Ginnae Ahn²,3*

1Division of Food Bioscience and Korea Nokyong Research Center, Konkuk University, Chungju,

27478, Republic of Korea2Department of Food Technology and Nutrition, Chonnam National University, Yeosu, Korea3Department of Marine Bio-Food Sciences, Chonnam National University, Yeosu,Korea4Department of Marine Life Science, Jeju National University, Jeju, Korea5College of Veterinary Medicine and Applied Radiological Science Institute, Jeju National

University, Jeju 690-756, Republic of Korea 6Division of Food and Nutrition, Chonnam National University, Gwang ju, Korea

P2-26 Protective effects of an enzymatic hydrolysate from Octopus ocellatus Gray meet against

H2O2-induced oxidative stress in Chang liver cells and Zebrafish embryo model

Seung Hong Lee1,a, Ju Hyung Um2,3,a, Eun A Kim4, WonWoo Lee4, Soo Yeon Park², Eui Jeong

Han2,3,Youngheun Jee 5, You-Jin Jeon⁴,Chang-Bum Ahn 6, and Ginnae Ahnb,c,*

¹Division of Food Bioscience and Korea Nokyong Research Center, Konkuk University, Chungju,

Korea

²Department of Food Technology and Nutrition, Chonnam National University, Yeosu, Korea

³Department of Marine Bio-Food Sciences, Chonnam National University, Yeosu, Korea4Department of Marine Life Science, Jeju National University, Jeju, Korea5College of Veterinary Medicine and Applied Radiological Science Institute, Jeju National

University, Jeju, Korea6Division of Food and Nutrition, Chonnam National University, Gwang ju, Korea

P2-27 “Supplementation with taurine and low fat chocolate milk post exercise does not improve

body composition but prevents protein catabolism in triathletes”

Flávia Giolo De Carvalho1, Bryan Steve Martinez Galan1, Priscila Carvalho Santos1, Kelly Pritchett2,

Karina Pfrimer3, Eduardo Ferriolli3, Julio Sergio Marchini3, Ellen Cristini de Freitas4

1Department of Food and Nutrition.School of Pharmaceutical Sciences of Araraquara.State

University of São Paulo – FCFAR/ UNESP.Araraquara-Highway, km 1, Araraquara, SP- Brazil.

14801-902. E-mail: [email protected]; [email protected],

[email protected] of Nutrition, Exercise and Health Sciences.Central Washington University-

CWU/WA.400 East University Way. Ellensburg, WA, US, 98926. E-mail: [email protected] of Internal Medicine.School of Medicine of Ribeirão Preto University of São Paulo –

FMRP/USP. Bandeirantes avenue, 3900. Ribeirão Preto, SP, Brazil, 14040-907. E-mail:

[email protected]; [email protected]; [email protected] of Physical Education and Sports of Ribeirão Preto University of São Paulo – EEFERP/USP.

Bandeirantes avenue, 3900. Ribeirão Preto, SP, Brazil, 14040-907. E-mail: [email protected].¹4

P2-28 Effect of supplementation with taurine-rich foods on school attitude assessment in Korean

high school students

So Hyun Park¹,Su Ji Park²,Kyung Ja Chang¹

¹Department of Food and Nutrition, Inha University,Incheon, Korea;

²Majors in Nutrition Education, Graduate School of Education,

P2-29 Consumption, awareness and preference of taurine-containing drinks in Korean female high

school students

So Hyun Park¹, Seon Hwa Lee², Kyung Ja Chang¹

¹Department of Food and Nutrition, Inha University, Incheon, Korea;

²Majors in Nutrition Education, Graduate School of Education, Inha University

P2-30 Positive correlations between frequency score of past taurine intake and total score of

cognitive function in the elderly with dementia and normal elderdy

Mi Ae Bae¹, Ranran GAO¹, Sung Hoon Kim², Kyung Ja Chang¹§

¹§Department of Food & Nutrition, Inha University, Incheon, Korea

²Department of Chemistry, Konkuk University, Seoul, Korea

P2-31 Significant difference in urinary excretion of taurine between the elderly with dementia and

normal elderdy

Mi Ae Bae¹, Ranran GAO¹, Kyung Ja Chang¹, Sung Hoon Kim²§

¹Department of Food & Nutrition, Inha University, Incheon, Korea

²§Department of Chemistry, Konkuk University, Seoul, Korea

P2-32 HPLC method for the determination of sulfur-containing biogenic amines in biological

specimens

Antonio Francioso1, Sergio Fanelli1, Daniele Vigli1,2, Rosaria Cavallaro3, Laura Ricceri2, Giorgia

Napoletani 1, Mario Fontana 1, Alessia Baseggio Conrado 4, Maria D’Erme 1 and Luciana Mosca 1

1Department of Biochemical Sciences “A.Rossi Fanelli”, Sapienza University of Rome, Italy2Department of Cell Biology and Neuroscience, Istituto Superiore di Sanità, Roma, Italy3Department of Surgery “P. Valdoni”, Sapienza University of Rome4Photobiology Unit, University of Dundee, Ninewells Hospital & Medical School, Dundee DD1 9S,

UK

P2-33 Effect of thiotaurine on human neutrophil activation explored by proteomic analysis

Elisabetta Capuozzo¹, Alessandra Giorgi¹, Alessia Baseggio Conrado¹², Sonia Canterini³, Mario

Fontana¹

¹Dipartimento di Scienze Biochimiche, Sapienza Università di Roma, Piazzale Aldo Moro 5 – 00185

Roma, Italia

²Photobiology Unit, University of Dundee, Ninewells Hospital & Medical School, Dundee DD1

9SY, UK

³Dipartimento di Psicologia, Sezione di Neuroscienze, Centro di Ricerca in Neurobiologia “Daniel

Bovet”, Sapienza Università di Roma, Via dei Sardi 70 – 00185 Roma, Italia

P2-34 Carbonate anion radical generated by the peroxidase activity of copper, zinc superoxide

dismutase: scavenging of radical and protection of enzyme by hypotaurine and cysteine sulfinic acid

Alessia Baseggio Conrado¹², Simonetta Maina¹, Harry Moseley², Antonio Francioso¹, Luciana

Mosca¹, Laura Pecci¹, Elisabetta Capuozzo¹, Mario Fontana¹

¹Dipartimento di Scienze Biochimiche, Sapienza Università di Roma, Piazzale Aldo Moro 5 00185 –

Roma, Italia

²Photobiology Unit, University of Dundee, Ninewells Hospital & Medical School, Dundee DD1

9SY, UK

P2-35 Effects of N-(D-Ribopyranosyl)Taurine sodium salt on the expression of pro inflammatory

cytokines in IL-1beta stimulated human endothelial cells

Kyoung-Soo Kim¹, Su Bin Na², Sung Hoon Kim³ Kyung Ja Chang²

¹East-West Bone & Joint Disease Research Institute, Kyung Hee University Hospital at Gangdong ,

149 Sangil-dong, Gangdong-gu , Seoul 134-727 , Korea

²Department of Food and Nutrition, Inha University, Incheon 402-751, Korea

³Department of Chemistry, Konkuk University, Seoul, Korea

P2-36 Supplemental Dietary taurine may ameliorate to Bone in OVX rats fed a high cholesterol diet

Choi, Mi-Ja

Department ofFood and Nutrition, Keimyung University, Daegu, Korea

P2-37 Effect of taurine and vitamin D on bone markers in Growing Female Rats Fed Calcium

Deficiency Diet

Choi, Mi-Ja

Department of Food and Nutrition, Keimyung University, Daegu, Korea

P2-38 Effects of Taurine and Vitamin D Supplementation on Serum Lipids and Antioxidant Enzymes

Activity

in Rats Fed Calcium Deficient Diet

Choi, Mi-Ja

Department of Food and Nutrition, Keimyung University, Daegu, Korea

P2-39 Taurine in drinking water recovers learning and memory in the mouse model of Alzheimer's

disease

HoChung Jang¹·², Hye Yun Kim¹·³, Ji Yoon Kim¹·², Hyunjin Vincent Kim¹·², Sejin Lee¹·², YoungSoo

Kim¹·²·*

¹Brain Science Institute, Korea Institute of Science and Technology, Seoul, Korea; ²Biological

Chemistry Program, Korea University of Science and Technology, Daejeon, Korea; ³Research

Institute, GoshenBiotech Inc., Namyangju-si, Gyeonggi-do, Korea

P2-40 EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation

of amyloid-β oligomers and plaques

Hye Yun Kim¹·³, Hyunjin Vincent Kim¹·², Seon Young Choi¹, C. Justin Lee¹, YoungSoo Kim¹·²·*

¹Brain Science Institute, Korea Institute of Science and Technology, Seoul, Korea; ²Biological

Chemistry Program, Korea University of Science and Technology, Daejeon, Korea; ³Research

Institute, GoshenBiotech Inc., Namyangju-si, Gyeonggi-do, Korea

P2-41 Motor neuronal protection by taurine in amyotrophic lateral sclerosis (ALS) model cell line

Na-Young Lee1 and Young-Sook Kang1,2

1College of Pharmacy and Research Center for Cell Fate Control, Sookmyung Women’s University,

Seoul, Korea;2Research Institute of Pharmaceutical Science (RIPS), Sookmyung Women’s University, Seoul,

Korea

P2-42 Taurine attenuates non-alcoholic fatty liver disease (NAFLD) through the inhibition of

oxidative stress

Ayuko Ono, Azusa Kawasaki, Masakazu Takahashi, Shigeru Murakami

Department of Bioscience, Fukui Prefectural University, Fukui, Japan

P2-43 Effect of Regular Exercise on Urinary Taurine Excretion after Taurine Drink Intake in High

school Girls

Sayami Yamamoto¹, Ami Yokoyama¹, Hideki Mori², Yukio Yamori²,Mari Mori²

Mukogawa Women's University Senior High School¹; Mukogawa Women's Univ Institute for World

Health Development. All rights reserved²

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