KLES University’s College of Pharmacy, Belagavi-10Multiple Choice Questions (MCQs)

COURSE: Pharmacy Class: B.Pharm VI Semester

SUBJECT: Advanced Pharmacognosy

Q. No Content AnswerUnit 1- Natural Products used as Color Pigments, Biopolymers,

Photosensitizing Agents and Flavors1 The colouring chemical (Curcumin) present in Turmeric is a

A) Terpenes B) AlkaloidsC) Steroids D)Glycosides

2 The colouring chemical (Crocin) present in saffron is aA) Terpene B) AlkaloidC) Steroid D) Glycoside

3 The colouring chemical (Bixin) present in Annato seeds is aA) Carotenoid B) AlkaloidC) Steroid D) Glycoside

4 The colouring chemical (Lycopene) present in Tomato is aA) Carotenoid B) AlkaloidC) Steroid D) Glycoside

5 The colouring chemical (Betalain) present in Beet root is a A) Carotenoid B) Alkaloid C) Flavonoid D) Glycoside

6 The colouring chemical (Capsanthin) present in Capsicum is a A) Glycoside B) Alkaloid C) Flavonoid D) Carotenoid

7 The colouring chemical (Lawsone) present in Henna is a A) Glycoside B) Alkaloid C) Phenol D) Carotenoid

8 The flavouring chemical present in Fennel is A) Menthol B) EugenolC) Anethole D) Pulegone

9 The flavouring chemical present in Ajowan is A) Citral B) EugenolC) Thymol D) Pulegone

10 The flavouring chemical present in Lemon is A) Citral B) LimoneneC) Borneol D) Pulegone

11 The flavouring chemical present in Cinnamon is A) Citral B) EugenolC) Borneol D) Pulegone

12 The flavouring chemical present in Cinnamon is A) Citral B) EugenolC) Borneol D) Pulegone

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13 Lactic acid polymers are used in the manufacture ofA) Liquid oral preparations B) ImplantsC) Tablets D) Capsules

14 Source of Lactic acid polymer A) Potatoes B) WheatC) Maize D) All

15 Natural photosensitizing agents are used in the treatment ofA) Typhoid B) PsoriasisC) Syphilis D) Hepatitis

16 Select the photosensitizing crude drugA) Bacopamonnieri B) PsoraleacorylifoliaC) Premnacordifolia D) Moringaoleifera

Unit 2- Adulteration of crude drugs and their types. Evaluation of crude drugs: Morphological, Microscopical, Physical, Chemical and Biological Methods with examples.

17 An example of crude drug adulterated with exhaustive drugA) Senna B) CorianderC) Datura D) Ephedra

18 Substitution of a genuine crude drug with substandard one is called as, A) Substitution B) MixingC) Adulteration D) Allied Drug

19 Cardamom is usually adulterated withA) Stalks of Cardamom B) Limestones C) Rodent faecal matter D) Mustard seeds

20 Harmful adulterant isA) Presence of vegetative matter B) Soil in grains C) Stones in drug D) Lead shot in Opium

21 Example of substitution with substandard drug isA) Capsicum minimum is replaced by Capsicum annum B) Clove is mixed with Mother Cloves C) Stramonium leaf is mixed with Stem D) Colored glass pieces mixed with Colophony

22 Example of substitution with exhausted drug isA) Senna B) Clove C) Opium D) Saffron

23 Saffron is admixed with dried flowers of, A) Carthamus tinctorius B) Exhausted saffron C) Scented bdellium D) Clove flower bud

24 Adulteration by exhausted ginger is detected from ginger byA) Shape B) Size C) Colour D) Water soluble ash

25 The quantitative evaluation of powdered crude drug without chemical and other methods is carried out byA) Lycopodium spore method B) Moisture determination method C) Powder microscopy D) None of the above

26 Lignified bulbous base trichomes are seen in A) Nux vomica B) CorrianderC) Ephedra D) Ginger

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27 An example of crude drug adulterated with exhaustive drugA) Senna B) CorianderC) Datura D) Ephedra

28 For tracing a magnified image of an object under a microscope we make use of A) Occular micrometer B) Camera lucidaC) Stage micrometer D) Polarimeter

29 Adulterants of Rauwolfiaserpentina are distinguished on the basis of A) Presence of sclerenchyma B) Absence of sclerenchyma C) Presence of parenchyma D) Absence of parenchyma

30 Lignified trichomes is characteristic of A) Catharanthuroseus B) Cassia angustifoliaC) Strychnousnux vomica D) Digitalis purpurea

31 A saturated picric acid solution in cold water used for the detection of alkaloids is known as A) Wagner’s reagent B) Hager’s reagent C) Dragendorff’s reagent D) Mayer’s reagent

32 Confirmation of drugs identity, determination of purity & quality & detection of nature of adulterant is known as A) Identification B) Confirmation C) Evaluation D) Determination

33 Organoleptic evaluation includes,A) Impressions on organs of senses B) Histological charactersC) Chemical nature D) Pharmacological uses

34 The following is the test for AlkaloidsA) Molischs test B) Dragendroff’s testC) Libermann – Burchard test D) Benedicts test

35 Qantiative microscopy is also known as A) Lycopodium spore method B) Stomatal methodC) Phytochemical method D) Water determination method

36 Karl fischer method is used in the determination of A) Moisture content B) Ash contentC) Bitterness content D) Chemical content

37 Parquetary arrangement of cells is the diagnostic character of A) Ginger B) Nux vomica C) Coriander D) Rauwolfia

38 Vittae is the diagnostic character of A) Ginger B) Nux vomica C) Coriander D) Rauwolfia

39 Stratified cork is the diagnostic character of A) Ginger B) Nux vomica C) Coriander D) Rauwolfia

40 Ash values of the crude determines the A) Organic constituents B) Inorganic constituents C) Cell constituents D) Chemical constituents

41 Acid insoluble ash values of the crude determines the A) Physiological ash B) ) Non Physiological ash

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C) Cell constituents D) Chemical constituents42 Aerenchyma is the diagnostic character of

A) Ginger B) Nux vomica C) Clove D) Rauwolfia

43 Adulteration by exhausted ginger is detected from ginger byA) Water insoluble ash B) Size C) Colour D) Water soluble ash

44 Heating a drug at 1050C in an oven to a constant weight is known asA) Volatile oil determination B) Moisture content determinationC) Melting point determination D) Ash value determination

45 The residue remaining after incineration is called asA) Ash B) ExtractC) Waste material D) Foreign matter

46 Swelling Index is used to determine amount of the following in the crude drugsA) Moisture B) Volatile oilsC) Crude fibres D) Mucilage

Unit 3 - Plant Bitters and Sweeteners Natural Sweeteners and Their Role in Health Care

47 Stevia is used asA) Bitter B) SweetnerC) Binder D) Disintegrant

48 Liquorice is used as A) Bitter B) SweetnerC) Antidiabetic D) Anticancer

49 Kalmegh is used as A) Bitter B) SweetnerC) Antidiabetic D) Anticancer

50 Gentian is used as A) Bitter B) SweetnerC) Antidiabetic D) Anticancer

51 The bitter principle of gentian is A) Gentisin B) AmarogentinC) Quassin D) Andrographolide

52 The bitter principle of Kalmegh is A) Gentiopicrin B) AmarogentinC) Quassin D) Andrographolide

53 The bitter principle of Quassia is A) Gentiopicrin B) AmarogentinC) Quassin D) Andrographolide

54 Example of Coumarone bitter principle isA) Humulon B) PicrotoxininC) Visnagin D) Rotenone

55 Example of phenolic bitter principle isA) Humulon B) Picrotoxinin

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C) Visnagin D) Rotenone56 Example of lactone bitter principle is

A) Humulon B) PicrotoxininC) Visnagin D) Rotenone

57 Example of Chromone bitter principle isA) Humulon B) PicrotoxininC) Visnagin D) Rotenone

58 Stevioside is a naturally occurring A) Bitter B) SweetnerC) Binder D) Disintegrant

59 Glycyrrhizin the natural sweetener is obtained from A) Liquorice B) SteviaC) Citrus D) Honey

60 Sucralose is an example of A) Natural sweetener B) Synthetic sweetener C) Semisynthetic sweetener D) None of the above

61 Santonin is a bitter principle obtained fromA) Artemisia maritima B) HumuluslupulusC) Anamirtacocculus D) Ammi visnaga

62 Khellin is a bitter principle obtained fromA) Artemisia maritima B) HumuluslupulusC) Anamirtacocculus D) Ammi visnaga

63 Picrotoxinin is a bitter principle obtained fromA) Artemisia maritima B) HumuluslupulusC) Anamirtacocculus D) Ammi visnaga

64 Lupulon is a bitter principle obtained fromA) Artemisia maritima B) HumuluslupulusC) Anamirtacocculus D) Ammi visnaga

Unit 4- Plant Hormones65 The following is an auxin that occurs naturally in plants

A) Napthylacetic acid B) Indolacetic acid C) Indole butyric acid D) Indole-3-acetonitrite

66 Endogenous plant growth regulator hormone is A) Indole B) Indene C) Gibberellins D) Glucose

67 The followings is a synthetic auxinA) IAA B) NAA C) IBA D) GA

68 Precursor of indole acetic acid isA) Glycine B) Methionine C) Isopentylpyrophosphate D) Tryptophan

69 All the following hormones are growth inhibiters exceptA) Absicic acid B) DorminC) Ethylene D) IAA

70 The following is the gaseous hormoneA) Absicic acid B) NAA C) IBA D) Ethylene

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71 All are synthetic hormone exceptA) IAA B) NAA C) 2,4-D D) 2,4,5-T

72 The following is not the function of auxinA) Inducing dormancy B) Enhancing cell division C) Inducing callus formation D) Maintaining apical dominance

73 The first kinetin isolated by miller was fromA) Coconut endosperm B) Maize grainsC) Herring sperm DNA D) Wheat grains

74 Cytokinins are predominately present in A) Permanent tissue B) Apical meristem C) Endodermis D) Cortical region

75 Cytokinin treatment enhancesA) Chlorophyl synthesis B) Chlorophyl degradation C) Protein degradation D) Water uptake

76 Gibberillins was named after a fungus calledA) Gibberellafujikuroi B) GibberellagaditijirriC) Gibberellaaccuminata D) Gibberellaafricana

77 High concentration of ethylene is present in A) Young leaves B) Meristematic regionsC) Buds D) Ripening fruits

Unit 5 - Introduction to alternative systems of medicines.a) Basic principles of Ayurveda, Siddha, Unani, Traditional Chinese Medicine and

Homoeopathy.b) Introduction to Ayurvedic preparations and method of preparation of Asava,

Arista, Gutika, Taila, Churna, Lehya and Bhasma78 Asavas are medicinal preparations made by

A) Soaking the drug in powder form B) Soaking the drug in decoction formC) Soaking the drug in paste form D)Soaking the drug in emulsion form

79 Asavas and Aristas are fermentedA) For removal of alcohol B) For liberation of alcoholC) For removal of water D) For liberation of water

80 PrekshepakaDravya areA) Fermentation destroyer B) Fermentation intiatersC) Fermentation terminaters D) None of the above

81 At the completion of fermentation in the preparation of Asava and AristaA) Effervescence is seen B) No effervescence is seen C) Turbidity is observed D) None of the above

82 Lehas are A) Solid preparations B) Liquid preparationC) Semisolid preparations D) Emulsified preparations

83 Gutikas areA) Solid preparations B) Liquid preparationsC) Semisolid preparations D) Emulsified preparations

84 Churna is defined asA) Fine powder of a drug B) Coarse powder of a drugC) Fine paste of a drug D) None of the above

85 Bhasma can be defined as6

A) Powder obtained by calcinations B) Liquid obtained by calcinationsC) Semisolid obtained by calcinations D) Emulsion obtained by calcinations

86 Sodhana in preparation of Bhasma is aA) Purification process B) Healing processC) Packing process D) None of the above

87 Tailas areA) Solid preparations B) Liquid preparationsC) Semisolid preparations D) Powdered preparations

88 Panchakarma in Ayurveda is adopted forA) Cleaning of the body B) Warming of the bodyC) Smoothening of the body D) None of the above

89 Siddha system of medicine is based on principles ofA) biguna B) RigvedaC) Triguna D) Atharveda

90 Unani system of medicine is based on principles ofA) 4 humours B) 5 humoursC) 4 Gunas D) 5 Gunas

91 The traditional Chinese system of medicine is based on the Chinese cosmology ofA) Yin and Yang B) Kin and KangC) bin and bang D) Yin and Zing

92 Tridosha exists inA) Chinese system of medicine B) Ayurveda C) Unani system of medicine D) Siddha system of medicine

93 Homeopathic system of medicine is based on doctrine ofA) Similiasimilibuscurantier B) DisimiliasimilibuscurantierC) Dismiliadismilibuscurantier D) None of the above

94 Hypothesis of ayurvedaA) Composed of 5 basic elements B) Composed of 3 basic elementsC) Composed of 7 basic elements D) Composed of 6 basic elements

95 Tridoshas areA) Vata, pitta, kapha B) Vata, rasa, raktaC) Pitta, meda, majja D) Mamsa, rasa, rakta

96 Ayurveda is an, A) Chinese system of medicine B) Siddha system of medicine C) Unani system of medicine D) Indian system of medicine

97 Hippocratic theory is composed of, A) 4 humours B) 3 humoursC) 5 humours D) 6 humours

98 Unani system of medicine is based on,A) Hippocratic theory B) Three basic elemental theoryC)Yin & yang theory D) Five basic elemental theory

99 Yin & yang meansA) Day & night B) Pitta &KaphaC) Rasa &Rakta D) Vata & pitta

100 Aim of Unani system is7

A)Treating the cause of disease B) Treating the symptoms of diseaseC) Diagnosing the symptoms of disease D) Diagnosing and treating the Symptoms of disease

101 Pythagorian theory is composed ofA) 5 proximate qualities B) 4 proximate qualities C) 3 proximate qualities D) 2 proximate qualities

102 Madar&Fufal areA) Siddha medicines B) Unani medicinesC) Homeopathic medicine D) Ayurvedic medicines

103 Abini&Haikalli areA) Unani medicines B) Homeopathic medicinesC) Ayurvedic medicines D) Siddha medicines

104 Homeopathic system of medicine was developed byA) Aristotle B) GalenC) Samuel Hahnemann D) Hippocrates

105 The Organon of medicine book is used in A) Unani system of medicine B) Siddha system of medicineC) Homeopathy system of medicine D) Chinese system of medicine

106 This system of medicine was identified with Dravidian cultureA)Siddha system of medicine B)Unani system of medicineC)Homeopathy system of medicine D)Indian system of medicine

107 The literature of Siddha system is inA)Telugu B) TuluC)Tamil D) SanskritUnit 6 - Stability Studies of Phytopharmaceuticals as per ICH Guidelines

108 ICH was incepted in the year A) 1990 B) 1991C) 1992 D) 1993

109 The inception of ICH took place at a meeting, hosted by EFPIA in A) Geneva B) BrugesC) Luxembourg D) Brussels

110 India registers under which region according to ICH guidelines for stability testing A) Hot and dry B) Hot and humidC) Moderate D) Mediterranean

111 The topics included under ICH are A) Quality B) EfficacyC) Safety D) All

112 The Countries included under ICH are A) European Union B) JapanC) USA D) All

113 As per ICH guidelines the sub-section Q1A (R2) deals with A) Photo stability testing B) Stability testing of new dosage formsC) Evaluation of stability data D) Stability testing of new drugs & products

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114 As per ICH guidelines the sub-section Q1B deals with A) Photo stability testing B) Stability testing of new dosage formsC) Evaluation of stability data D) Stability testing of new drugs & products

115 As per ICH guidelines the sub-section Q1E deals with A) Photo stability testing B) Stability testing of new dosage formsC) Evaluation of stability data D) Stability testing of new drugs & products

116 As per ICH guidelines the sub-section Q2A deals with A) Methodology B) Definitions and terminologyC) Impurity testing of new drugs D) Stability testing of new drugs & products

117 As per ICH guidelines the sub-section Q2B deals with A) Methodology B) Definitions and terminologyC) Impurity testing in new drugs D) Stability testing of new drugs & products

118 As per ICH guidelines the sub-section Q3C deals with A) Methodology B) Definitions and terminologyC) Impurity testing in new drugs D) Impurities: Residual solvents

119 As per ICH guidelines the sub-section Q3A deals with A) Methodology B) Definitions and terminologyC) Impurity testing in new drugs D) Impurities: Residual solvents

120 For accelerated stability studies as per ICH guidelines with storage condition as controlled room temperature the testing condition is A) 30oC & 30% RH for 6 months B) 40oC & 75% RH for 6 monthsC) 25oC & 60% RH for 12 months D) 60oC & 75% RH for 2 days

121 For intermediate stability studies as per ICH guidelines with storage condition as controlled room temperature the testing condition is A) 30oC & 60% RH for 6 months B) 40oC & 75% RH for 6 monthsC) 25oC & 60% RH for 12 months D) 60oC & 75% RH for 2 days

122 For long term (Real time) stability studies as per ICH guidelines with storage condition as controlled room temperature the testing condition is A) 30oC & 60% RH for 6 months B) 40oC & 75% RH for 6 monthsC) 25oC & 60% RH for 12 months D) 60oC & 75% RH for 2 days

123 For Stress testing stability studies as per ICH guidelines with storage condition as controlled room temperature the testing condition is A) 30oC & 60% RH for 6 months B) 40oC & 75% RH for 6 monthsC) 25oC & 60% RH for 12 months D) 60oC & 75% RH for 2 days

124 For accelerated stability studies as per ICH guidelines with storage condition as Refrigerated condition the testing condition is A) 10oC & 50% RH for 6 months B) 25oC & 60% RH for 6 monthsC) 5oC for 12 months D) 40oC & 75% RH for 2 days

125 For intermediate stability studies as per ICH guidelines with storage condition as Refrigerated condition the testing condition isA) 10oC & 50% RH for 6 months B) 25oC & 60% RH for 6 monthsC) 5oC for 12 months D) 40oC & 75% RH for 2 days

126 For long term (Real time) stability studies as per ICH guidelines with storage condition as Refrigerated condition the testing condition is A) 10oC & 50% RH for 6 months B) 25oC & 60% RH for 6 monthsC) 5oC for 12 months D) 40oC & 75% RH for 2 days

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127 For Stress testing stability studies as per ICH guidelines with storage condition as Refrigerated condition the testing condition is A) 10oC & 50% RH for 6 months B) 25oC & 60% RH for 6 monthsC) 5oC for 12 months D) 40oC & 75% RH for 2 days

128 For accelerated stability studies as per ICH guidelines with storage condition as Freezer condition the testing condition is A) 10o for 6 months B) 5oC for 6 monthsC) -20oC for 12 months D) 25oC & 60% RH for 2 days

129 For intermediate stability studies as per ICH guidelines with storage condition as Freezer condition the testing condition is A) 10o for 6 months B) 5oC for 6 monthsC) -20oC for 12 months D) 25oC & 60% RH for 2 days

130 For long term (Real time) stability studies as per ICH guidelines with storage condition as Freezer condition the testing condition is A) 10o for 6 months B) 5oC for 6 monthsC) -20oC for 12 months D) 25oC & 60% RH for 2 days

131 For Stress testing stability studies as per ICH guidelines with storage condition as Freezer condition the testing condition isA) 10o for 6 months B) 5oC for 6 monthsC) -20oC for 12 months D) 25oC & 60% RH for 2 days

132 Indicative substance as per ICH guidelines isA) Secondary metabolite B) Primary metaboliteC) Biomarker D) All

Unit 7- Extraction and Analytical Profile of Phytopharmaceuticals133 Aloein present in Aloe can be detected by reversed phased HPLC using the

solvent systemA) Methanol: water B) Acetonitrile: phosphoric acidC) Acetonitrile: Glacial acetic acid D) Methanol: Ammonium phosphate

134 Detecting reagent used analysis of Aloe by TLC/HPTLC is A) 5 % Ethanolic KOH B) 5 % Vanillin Sulphuric acidC) 5 % EthanolicPhosphomolybdic acid D) 5 % HCL

135 Aloe barbadensis belongs to the family A) Rubiaceae B) LiliaceaeC) Apiaceae D) Umbelliferae

136 Hydrocotyleasiatica belongs to the familyA) Apiaceae B) RubiaceaeC) Apidae D) Umbelliferae

137 Botanical name of Cape aloe is A) Aloe barbadensis B) Aloe perryiC) Aloe classenii D) Aloe ferox

138 Botanical name of Curacao aloe is A) Aloe barbadensis B) Aloe perryiC) Aloe classenii D) Aloe ferox

139 Botanical name of Socotrine aloe is A) Aloe barbadensis B) Aloe perryiC) Aloe classenii D) Aloe ferox

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140 Botanical name of Zanzibar aloe is A) Aloe barbadensis B) Aloe perryiC) Aloe classenii D) Aloe ferox

141 Chose the appropriate TLC/HPTLC solvent system for identification of GlycyrrhizinA) Toluene: Ethyl acetate : Glacial acetic acid (12.5:7.5:0.5)B) n-butanol: Glacial acetic acid : Water (4:1:5)C) Toluene: Ethyl acetate : Ammonia (12.5:7.5:0.5)D) Methanol: Water (9:1)

142 Chemically glycyrrhizin is a A) Carotenoid B) DitereneC) Sesquiterpene D) Triterpenoid

143 Glycyrrhizin is a mixture of _______and ______salts of glycyrrhizinic acid A) Sodium & Potassium B) Calcium & PotassiumC) Calcium & Sodium D) Calcium & Magnesium

144 Chose the appropriate TLC/HPTLC solvent system for identification of AsiaticosideA) n-butanol: Ethyl acetate : Glacial acetic acid (12.5:7.5:0.5)B) n-butanol: Ethyl acetate : Water (4:1:5)C) Chloroform: Glacial acetic acid: Methanol: Water (60:32:12:8)D) Chloroform: Ammonia: Pet.ether: Hexane (60:32:12:8)

145 Chemically Asiaticoside is a A) Carotenoid B) DitereneC) Sesquiterpene D) Triterpenoid

146 Chose the appropriate TLC/HPTLC solvent system for identification of CurcuminoidsA) n-butanol: Ethyl acetate : Glacial acetic acid (12.5:7.5:0.5)B) n-butanol: Ethyl acetate : Water (4:1:5)C) Chloroform: Methanol (90:10)D) Chloroform: Ethanol: Glacial acetic acid (95:5:1)

147 Berberin is a ________ type of alkaloid A) Indole B) IsoquinolineC) Tropane D) Imidazole

148 Chose the appropriate TLC/HPTLC solvent system for identification of BerberinA) n-butanol: Ethyl acetate : Glacial acetic acid (12.5:7.5:0.5)B) n-butanol: Ethyl acetate : Water (4:1:5)C) n-Propanol: Formic acid: Water (90:1:9)D) Chloroform: Ethanol: Glacial acetic acid (95:5:1)

149 Chose the appropriate TLC/HPTLC solvent system for identification of PiperineA) n-butanol: Ethyl acetate : Glacial acetic acid (12.5:7.5:0.5)B) Benzene: Ethyl acetate : Diethyl Ether (60:30:10)C) n-Propanol: Formic acid: Water (90:1:9)D) Chloroform: Ethanol: Glacial acetic acid (95:5:1)

150 The source of piperine is A) Piper abiaticum B) Piper longumC) Piper indicum D) Piper lingimum

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151 The source of berberin is A) Berberis arista B) BerberisaristataC) Berberisindica D) Berberisasiatica

152 Chose the appropriate HPLC solvent system for identification of Piperine by RP HPLCA) n-butanol: Ethyl acetate : Glacial acetic acid (12.5:7.5:0.5)B) Methanol: Water (69:31)C) n-Propanol: Formic acid (99:1)D) Chloroform: Ethanol: Glacial acetic acid (95:5:1)

Staff In-Charge Head of Department Principal

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