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Visualization Of The Insertion Site EXIT SITE INFECTION EXIT SITE INFECTION WHAT IS THE CLINICAL SIGNIFICANCE? The conclusion of the combination of 2 randomized trials involving 1,263 central venous catheter was: WHY? Inflammation at the insertion site is not indicative of infection at the insertion site. Many types of bacteria responsible for CRBSI do not cause visible site reaction (ie, coagulase negative staph bacteria). Safdar/Maki 1 BIOPATCH WITH TRANSPARENT DRESSING References: 1. Safdar N, Maki DG. The pathogenesis of catheter-related bloodstream infection with noncuffed short-term central venous catheters. Intensive Care Med. 2004;30:62-67 2. O'Grady NP, Alexander M, Dellinger EP, et al. Guidelines for the prevention of intravascular catheter-related infections. Centers for Disease Control and Prevention. MMWR Recomm Rep. 2002 Aug 9;51(RR-10):1-29. ETHICON Inc. 2009, BP-078 TRYING TO SEE ERYTHEMA OR REDNESS FOR ASSESSMENT OF EXIT SITE INFECTION? 2002 CDC GUIDELINES FOR THE PREVENTION OF INTRAVASCULAR CATHETER-RELATED INFECTIONS 2 defines the following: “Erythema, or induration within 2 cm from the catheter exit site, in the absence of concomitant bloodstream infection (BSI) and without concomitant purulence” Exit Site Infection “Tenderness, erythema, or site induration >2 cm from the catheter site along the subcutaneous tract of a tunneled (eg, Hickman or Broviac) catheter, in the absence of concomitant BSI” Clinical Exit Site Infection Over the past 15 years BIOPATCH ® Protective Disk with CHG has been evaluated in multiple studies and controlled randomized trials. It is the only device of its kind with an FDA-cleared indication to reduce local infections, catheter-associated bloodstream infections (CRBSI), and skin colonization of microorganisms commonly related to CRBSI, in patients with central venous or arterial catheters. “The sensitivity of local infection for the diagnosis of CVC-related BSI was dismal (0-3%).” Safdar/Maki 1 IF YOU VISUALIZE THE SITE, WHAT ARE YOU LOOKING FOR? EdEma/swElling Touch induraTion/hardEning Touch TEndErnEss Touch hEaT Touch EryThEma/rEdnEss visual LOCAL SIGNS OF INFECTION Please visit www.biopatch.com for Full Prescribing Information BIOPATCH ® Overlaying Erythema BIOPATCH does not interfere with as defined by the CDC ® erythema visualization of clinically relevant

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Page 1: Visualization Of The EXIT SITE INFECTION? Insertion 2 defines the

Visualization Of The Insertion Site

EXIT SITE INFECTIONEXIT SITE INFECTION

WHAT IS THE CLINICALSIGNIFICANCE?

The conclusion of the combination of 2 randomized trials involving 1,263 central venous catheter was:

WHY? Inflammation at the insertion site is not indicative of infection at the insertion site. Many types of bacteria responsible for CRBSI do not cause visible site reaction (ie, coagulase negative staph bacteria).Safdar/Maki 1

BIOPATCH WITH TRANSPARENTDRESSING

References: 1. Safdar N, Maki DG. The pathogenesis of catheter-related bloodstream infection with noncuffed short-term central venous catheters. Intensive Care Med. 2004;30:62-67 2. O'Grady NP, Alexander M, Dellinger EP, et al. Guidelines for the prevention of intravascular catheter-related infections. Centers for Disease Control and Prevention. MMWR Recomm Rep. 2002 Aug 9;51(RR-10):1-29. ETHICON Inc. 2009, BP-078

TRYING TO SEE ERYTHEMA OR REDNESS FOR ASSESSMENT OF EXIT SITE INFECTION?2002 CDC GuIDelIneS FoR The PRevenTIon oF InTRavaSCulaR CaTheTeR-RelaTeD InFeCTIonS2 defines the following:

“erythema, or induration within 2 cm from the catheter exit site, in the absence of concomitant bloodstream infection (BSI) and without concomitant purulence”

Exit Site Infection

“Tenderness, erythema, or site induration >2 cm from the catheter site along the subcutaneous tract of a tunneled (eg, hickman or Broviac) catheter, in the absence of concomitant BSI”

Clinical Exit Site Infection

over the past 15 years BIoPaTCh® Protective Disk with ChG has been evaluated in multiple studies and controlled randomized trials. It is the only device of its kind with an FDa-cleared indication to reduce local infections, catheter-associated bloodstream infections (CRBSI), and skin colonization of microorganisms commonly related to CRBSI, in patients with central venous or arterial catheters.

“The sensitivity of local infection for the diagnosis of CvC-related BSI was dismal (0-3%).” Safdar/Maki 1

IF YOUVISUALIZE THE SITE,WHAT AREYOU LOOKING FOR?

EdEma/swElling Touch

induraTion/hardEning Touch

TEndErnEss Touch

hEaT Touch

EryThEma/rEdnEss visual

LOCAL SIGNS OF INFECTION

Please visit www.biopatch.com for Full Prescribing Information

BIoPaTCh® Overlaying Erythema

BIOPATCH does not interfere with

as defined by the CDC

®

erythemavisualization of clinically relevant

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