vitamin journal report

8/18/2019 Vitamin Journal Report

1/10

Hepatoprotective Efect o Vitamin C(Ascorbic Acid)

Prepared by: Maria AthennaMallari


2/10

Sorces

!eerence: (Stan"eland #$%&''


3/10

• Male ( and above):*+ m"

• ,emale ( andabove): *' m"

!eerence: (Cora-on .arba%&'')

!ecommended /aily Vitamin C

!e0irement


4/10

Hepatoprotective Efect

!eported sho1ed that Vitamin C and its

antio2idative property attenate hepatic dama"eindced by some chemical a"ents especially inanimals$ (.ashandy S$ A$% &')


5/10

,nction o Vitamin C

• #hey reported Vitamin C normali-ed

levels o alanine aminotranserase%aspartate aminotranserase% al3alinephosphatase% blood hydropero2ide

and malondialdehyde in liver ocarbontetrachloride into2icated rats$(Ademyi1a% 445) (6atao3a% &'&)


6/10

Ho1 it 7or3s

• Ascorbic acid redced 8Cypermethrin9

indced Cytoto2icity in rat hepatocytes byrecoverin" ;'< o "ltathione and +5<decrease in "amma "ltamyltranspeptidase$

• Ascorbic acid 1as also able to preserved''< o cell inte"rity and modlatedalanine aminotranserase and aspartateaminotranserase$ (6atao3a% &'&)


7/10

• Some metals andheavy metals li3e

copper% lead%chromim andcadmim are3no1n to indce

hepatic dama"e inanimals andhmans$ (!a=amanic3am%&'') (El9#ohany% &'')


8/10

• /r"s are chemical a"ents sed orthe treatment o ailments$ Somedr"s are 3no1n to have hepatoto2ic

efects in hman and animals$Vitamin C has sho1n tremendosprotective efect a"ainst dr"s and

chemical a"ents indcedhepatoto2icity$ (Al9shathly% &'&)


9/10

Conclsion

>t 1as observed that vitamin Ce2hibited a reptable hepatoprotective

efect in hmans and animals by

inhibited hepatoto2icity indced bydr"s% heavy metals% or"anophosphate

insecticides and some chemical

a"ents$


10/10

Ademyi1a% ?$ (445)$ Vitamin C in CC5 Hepatoto2icity9A Preliminary!eport$ Human Experimental Toxicology % '*9'4$Al9shathly% M$ !$ (&'&)$ #he preventive Efect o Vitamin C pon AddedMethyl #ertiary .tyl Ether (M#.E) in /rin3in" 7ater on the @iver oAlbino Mice$ International Journal of research in Chemistry andEnvironment % &59&&$.ashandy S$ A$% A$ S$ (&')$ Carbon #etrachloride9>ndced Hepatoto2icityand ephroto2icity in !ats: protective !ole o Vitamin C$ Journal ofPharmacology and Toxicology % &B9&4&$Cora-on .arba% M$ >$ (&'')$ !ecommended ener"y and ntrient inta3esor ,ilipinos &''&$ Asia Pacic Journal Clinical Nutrition% B4495'5$Elias Adi31% ?$ /$ (&'B)$ Hepatoprotective Efect o Vitamin C (AscorbicAcid)$ Pharmacology Pharmacy % 594&$El9#ohany% M$ M$ (&'')$ Efects o Anti9o2idant on @ead9>ndced ?2idative

/ama"e and !eprodctive /ysnction in Male !abbits$ Journal of American !cience% ;B9 ;&&$6atao3a% #$ (&'&)$ Comparative Stdy on the >nhibitory efects oAntio2idant Vitamin and !adon on Carbon #etrachloride9>ndcedHepatopathy$ Journal of "adiation "esearch% 9'$Marissa Selner% E$ .$ (&';% anary &*)$ Car#on Tetrachloride Poisoning$ !etrieved rom Healthline 7ebsite:http:DD111$healthline$comDhealthDcarbon9tetrachloride9

poisonin"?vervie1!a=amanic3am% V$ (&'')$ Efect o Heavy Metals >ndced #o2icity onMetabolic .iomar3ers in Common Carp$ %ae&o International Journal of!cience and Technology % 4&9&''$Stan"eland #$% !$ S$ (&'')$ Total Antioxidant Activity in '( )gandan *ruitsand +egeta#les$ Elsevier$
http://www.healthline.com/health/carbon-tetrachloride-http://www.healthline.com/health/carbon-tetrachloride-

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