Benign and malignant disease of the vulva

Khalid Sait ( FRCSC)

Gynecological Oncology Professor

Faculty of Medicine King Abdulaziz University

Symptoms of Vulvar Disease

•  Itching •  Burning •  Dyspareunia •  Discharge •  Bleeding

General Pathology Term. •  Epidermis •  Acanthosis •  Parakeratosis •  Hyperkeratosis

Vestibular Micropapillomatosis

General Guide to Diagnosis

•  White Lesions •  Red Lesions •  Brown/Bluish Lesions

White Lesions •  Vitilligo •  Nonneoplastic epithelial disorders

Nonneoplastic Epithelial Disorders - Vulva

•  Squamous cell hyperplasia •  Lichen Sclerosis •  Other dermatosis

ISSVD 1987

Lichen Sclerosis •  Steroid •  Testesterone •  Progesterone

Squamous cell hyperplasia

•  Steroid

Red Lesions •  Infective •  Dermatitis •  Psoriasis •  Pagets •  VIN/Ca

HPV - Treatment •  Observation •  Podophyllin •  Trichloroacetic acid •  Interferon •  Imiquimod ( Aldara) •  Excision /Laser

Brownish/Bluish Lesions •  VIN •  Naevi/Melanoma •  Carcinoma

Key Points •  Inspection/ Palpation •  Biopsy prior to treatment •  Medical therapy for majority of

benign lesions