w: supported by research capacity strengthening among young african scientists : from gmp to mcdc...
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w: www.mcdconsortium.org
Supported by
Research Capacity Strengthening among young African Scientists :
from GMP to MCDC
Dr. Evelyn Korkor Ansah (Ghana)
STRENGTHENING RESEARCH
CAPACITY
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Academic progression
Qualified in Medicine in
GhanaMPH PhD award -
GMP in 2002
Re-entry Grant -GMP in 2006
Additional Funds from ACT
Consortium
Senior Fellowship
Award - MCDC in 2010
Fellow of the Ghana College of
Physicians
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Currently Deputy Director, Research & Development Division of GHS since 2011 Adjunct Lecturer in Epidemiology, MSc Clinical Trials Course at SPH,
University of Ghana Adjunct Lecturer at the Ghana Institute of Management and Public
Administration Member of Steering Committee, ACT Consortium, LSHTM Chairperson of the Institutional Review Board (IRB) of the Dodowa
Health Research Centre, Ghana MCDC Investigator Currently supervising two PhD and an MSc student, advisor to
another PhD student
STRENGTHENING RESEARCH
CAPACITY
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Role of GMP/MCDC in my progression• A twelve-year period of linkage with GMP/MCDC
including:Capacity strengthening (PhD)Support for researchSupport for Personal Development Programme (PDP)Mentoring and Leadership Development Programme (LDP)
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Passing on the legacy of RCS • Setting up a new department in the Research Division of GHS
with a mandate that includes providing RCS for health staff at all levels
• Developing a Handbook for Operational Research for use by Regional/District health teams in Ghana
• Providing short courses on OR (Research Ethics, Data Management using EPI Data, Scientific Writing, Dissemination of research findings) – accepted for CPD of Doctors
• Awarded WHO/TDR short term grant for RCS to train 5 teams • Adjunct lecturer in OR and Epidemiology in two Institutions
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RCS among different categories of health teams
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An individually randomized controlled trial of RDTs in two
types of Health Facility settings in rural Ghana
The impact of introducing mRDTs for the management of fever in the private
retail sector in Ghana: a cluster RCT
Clinician and patients percept- -ions of the use of mRDTs for
diagnosis of malaria
The cost-effectiveness of malaria diagnostics in public health facilities in rural Ghana
PATIENT
Research Work: A compendium of studies each filling an information niche (diagnostics)
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Impact of work on Local Policy
• Member of the Task Team on Malaria Laboratory Policy
• Contributed to the development of National Guidelines for Laboratory Diagnosis of Malaria
• • Malaria Rapid Diagnostic Tests
introduced into health facilities with great input from results of study
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Current Research Question
• Can we trust chemical sellers in drug retail shops to safely and effectively carry out rapid diagnostic testing for malaria prior to dispensing antimalarials in order to reduce the abuse and overuse of ACTs and subsequent development of resistance?
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The Intervention2 trial arms• Intervention arm carried out a test using
RDT prior to dispensing medication• The control arm dispensed medication to
clients without testing as was standard practice
• RDTs were provided by the study team on a monthly basis free of charge to chemical sellers and clients
• Chemical sellers in the 2 trial arms received separate 3-dy/4dy training
MCDC_ASTMH 2014
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Preparatory Activities and formative research
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Filming followed by community sensitization
13
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Supporting logistics• Bin for disposal of sharps• Bin for disposal of other waste• Storage box for test items i.e gloves, test kits etc (adapted from
the TACT study, Tanzania)• Posters on treatment schedule for first line ACTs for adults and
children• Training certificate for display• Job Aids
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Summary• RDTs to guide dispensing practice of chemical sellers has a significant
impact on the dispensing of AMs and also ACTs in this setting• There was no change in prescribing ACTs to true malaria cases, but a
significant reduction in AMs of all types and ACTs to non malaria cases observed
• A more rapid change in behavior observed among shopkeepers than that found when RDTs were first introduced to health staff in the same setting
• No safety concerns were identified as a result of introducing RDTs• RDTs were acceptable to both clients and chemical sellers• A number of operational issues need to be considered
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In conclusion
• My training has maximized my potential as a scientist and enabled me to contribute both locally and internationally to capacity building of other scientists and evidence-based decision making for health
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Acknowledgements• Prof. Brian Greenwood who believed that building capacity in
young African scientists will yield great dividends • Prof. Chris Whitty, my PhD Supervisor and mentor• Director and Secretariat, Gates Malaria Partnership, LSHTM• Director and Secretariat, Malaria Capacity Development
Consortium, LSHTM• Director and Secretariat, ACT Consortium, LSHTM• My very supportive husband and children• Co-Investigators and colleagues
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Thanks for listening