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Waltz Round the CycleOnce a jolly pyruvate enters the matrixOf a mitochondrion, so they sayA decarboxylating, complex dehydrogenaseConverts it to acetyl co-enzyme A.

Waltz round the cycleWaltz round the cycleWaltz round the TCA cycle today

A decarboxylating, complex dehydrogenaseTurns pyruvate to acetyl CoA.

Oxaloacetate looking for a partnerThinks active acetate looks OK;Condensing enzyme arranging a mergerMakes a new citrate, and kicks out CoA.

Waltz round the cycleWaltz round the cycleWaltz round the TCA cycle today

Condensing enzyme arranging a mergerMakes a new citrate, and kicks out CoA.

Along comes aconitase, a hydro-dehydratase,Gives isocitrate reversibly.Then its dehydrogenase gives NADH,Carbon dioxide and a-OG.

Waltz round the cycleWaltz round the cycleWaltz round the TCA cycle with me

Then its dehydrogenase gives NADH,Carbon dioxide and a-OG.Off with the CO2. Another oxidationJust like the PDC previously.Succinyl CoA with a thiokinaseYields succinate and GTPWaltz round the cycleWaltz round the cycleWaltz round the TCA cycle with me

Succinyl CoA with a thiokinaseYields succinate and GTPSuccinates oxidized by its dehydrogenaseReducing FAD, fiving fumarate;Fumarase makes malate; another dehydrogenaseGenerates oxaloacetate.Waltz round the cycleWaltz round the cycleWaltz round the TCA cycle today

Fumarase makes malate; another dehydrogenaseGenerates oxaloacetate.