weekly afp and vpd update for week 09, 2013 data as of 04 march 2013

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SEARO, New Delhi, 2013 Immunization and Vaccine Development (IVD) SEARO Protecting People from Vaccine Preventable Diseases Weekly AFP and VPD Update for Week 09, 2013 Data as of 04 March 2013

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Weekly AFP and VPD Update for Week 09, 2013 Data as of 04 March 2013. = Most recent P1 Wild polio case. Districts with cases in 2011. Districts with cases in current week. Wild Polio Virus India, 2011. *Dots are randomly placed within blocks (Sub-districts). Data as of 04 Mar 2013. - PowerPoint PPT Presentation

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Page 1: Weekly AFP and VPD Update for Week 09, 2013 Data as of 04 March 2013

SEARO, New Delhi, 2013

Immunization and VaccineDevelopment (IVD) SEARO

Protecting People from Vaccine Preventable

Diseases

Weekly AFP and VPD Update for Week 09, 2013Data as of 04 March 2013

Page 2: Weekly AFP and VPD Update for Week 09, 2013 Data as of 04 March 2013

SEARO, New Delhi, 2013

Wild Polio VirusIndia, 2011

*Dots are randomly placed within blocks (Sub-districts)

= Most recent P1 Wild polio case

101

1

P1 Wild13-Jan-2011; District Howra, West Bengal

P3 Wild -

Date and location of most recent case

Wild Polio Cases, 2011Total P1 Wild cases

Total polio cases

Total districts with wild cases

Total P3 Wild cases

Districts with cases in 2011

Districts with cases in current week

Data as of 04 Mar 2013

Page 3: Weekly AFP and VPD Update for Week 09, 2013 Data as of 04 March 2013

SEARO, New Delhi, 2013

Wild Polio Cases by Type (P1, P3) and Month of OnsetIndia, 2007-2013

Data as of 04 Mar 2013

P1 P3 P1 P3 P1 P3 P1 P3 P1 P3 P1 P3 P1 P3Jan 15 9 1 111 7 7 2 14 1 0 0 0 0 0Feb 6 8 2 51 2 3 1 2 0 0 0 0 0 0Mar 8 6 1 39 3 13 0 0 0 0 0 0Apr 3 11 0 40 4 9 1 1 0 0 0 0May 7 25 1 33 4 19 2 0 0 0 0 0Jun 1 29 3 35 8 71 1 1 0 0 0 0Jul 10 54 7 46 6 83 3 2 0 0 0 0Aug 10 67 21 46 11 108 4 3 0 0 0 0Sep 4 77 17 32 19 126 3 0 0 0 0 0Oct 3 95 5 27 11 118 0 1 0 0 0 0Nov 8 194 8 16 3 57 0 0 0 0 0 0Dec 5 216 9 8 1 47 1 0 0 0 0 0

Sub-Total 80 791 75 484 79 661 18 24 1 0 0 0 0 0Total*

2012

0

2011

1

2007 2013

0

20102009

740871 559 42

Month2008

Page 4: Weekly AFP and VPD Update for Week 09, 2013 Data as of 04 March 2013

SEARO, New Delhi, 2013

Monthly Distribution of AFP CasesSEAR, 2012 – 2013

Data as of 04 Mar 2013

Bangladesh 1566 195 122 112 135 168 140 145 146 114 153 128 119 84 152 43 04-Mar-13

Bhutan 10 1 1 1 1 2 0 1 0 1 0 3 0 0 1 0 04-Mar-13

DPR Korea 127 10 8 8 12 7 14 22 10 15 7 8 9 7 10 0 18-Feb-13

India 61007 6168 4606 4119 4172 4268 5008 4994 5459 7135 7391 5313 4485 4057 4065 2103 01-Mar-13

Indonesia 1939 184 164 160 174 200 203 163 200 127 139 146 113 150 149 35 01-Mar-13

Maldives 4 0 1 0 0 1 0 0 2 0 0 0 0 0 0 0 19-Nov-12

Myanmar 457 37 18 9 11 22 36 42 44 58 96 64 33 24 30 7 01-Mar-13

Nepal 641 49 50 51 47 52 61 69 70 92 69 38 21 21 29 20 01-Mar-13

Sri Lanka 75 9 8 5 10 5 12 5 5 6 7 3 5 4 8 1 01-Mar-13

Thailand 289 27 22 24 25 7 20 15 30 30 30 37 27 22 17 10 01-Mar-13

Timor-Leste 5 1 1 0 1 2 0 0 0 0 1 0 0 0 1 0 15-Feb-13

TOTAL 66120 6681 5001 4489 4588 4734 5494 5456 5966 7578 7893 5740 4812 4369 4462 2219

Jan

-13

Feb

-12

No

v-12

Jul-

12

Mar

-12

Jun

-122012

total AFP Ja

n-1

2

Au

g-1

2

Ap

r-12

AFP cases by month of paralysis onset, last 14 months (data from weekly case-based reports)

Oct

-12

Sep

-12

May

-12 Date of

last reportD

ec-1

2

Feb

-13

Country2013

AFP to date

Page 5: Weekly AFP and VPD Update for Week 09, 2013 Data as of 04 March 2013

SEARO, New Delhi, 2013

Primary Culture Results from AFP Cases, 2012

Data as of 04 Mar 2013

<=14 days

>14 days

Vac

cin

e

Wil

d

Bangladesh IPH, Dhaka 1552 47 1 263 1241 0 0 3097 87.5 13.8 315 8 0

Bhutan NIH, Bangkok 9 0 0 0 9 0 0 21 100 0 0 0 0

DPRK NPL, Pyongyang 116 0 0 13 94 0 9 277 93 10.6 0 0 0

BJMC, Ahmedabad 6511 297 29 1294 4890 1 0 13032 99.6 16.2 143 12 0

NIV, Bangalore 5486 249 50 1474 3713 0 0 10985 95.1 22.8 19 1 0

IoS, Kolkatta 8873 253 18 873 7729 0 0 17715 97.8 7.3 26 3 0

KIPM, Chennai 8369 278 44 1732 6315 0 0 16747 99.2 17.2 20 2 0

NCDC, Delhi 10398 482 26 1219 8669 2 0 20713 98.9 9.4 32 2 0

CRI, Kasauli 2414 85 7 392 1930 0 0 4851 99.8 13.6 21 1 0

SGPGI, Lucknow 14609 591 141 4419 9458 0 0 29249 98.9 21.4 60 2 0

ERC, Mumbai 2867 95 18 749 2005 0 0 5770 91.3 22.8 101 4 0

India Sub Total 59527 2330 333 12152 44709 3 0 119062 98.2 16.0 422 27 0

Biofarma, Bandung 568 3 0 51 513 0 1 1129 97 8.2 0 0 0

NIHRD, Jakarta 729 6 0 78 645 0 0 1453 100 9.4 5 0 0

PHL, Surabaya 613 11 1 64 537 0 0 1216 100 9.0 0 0 0

Indonesia Sub Total 1910 20 1 193 1695 0 1 3798 99.0 8.9 5 0 0

Maldives MRI, Colombo 3 0 0 0 3 0 0 6 100 0 0 0 0

Myanmar NHL, Yangon 457 2 0 68 387 0 0 916 93 13.6 0 0 0

Nepal NIH, Bangkok 619 16 2 145 455 0 1 1237 100 19.6 129 2 0

Sri Lanka MRI, Colombo 46 2 0 2 42 0 0 101 97 3.0 299 9 0

Thailand NIH, Bangkok 272 11 0 13 248 0 0 557 99.8 3.6 0 0 0

Timor-Leste PHL, Surabaya 3 0 0 0 3 0 0 5 100.0 0 0 0 0

64514 2428 337 12849 48886 3 11 129077 97.9 15.6 1170 46 01 Calculation based on date specimen received in laboratory subtracted from date data received in SEARO as shown in Table 1.2 Stool samples collected from contact and healthy children survey.

Specimens from other

Positive Culture

Positive Culture +

NPEV

% Primary Culture Reports Within 14

days % N

PE

V

Number received

by lab

Number of AFP cases with

specimens received in Lab

Negative

AFP cases AFP specimens

Primary culture results from AFP cases 2012

SEAR

India

Indonesia

Pending1

Country Polio Laboratories NPEV Only

Results

Received by lab

Page 6: Weekly AFP and VPD Update for Week 09, 2013 Data as of 04 March 2013

SEARO, New Delhi, 2013

Primary Culture Results from AFP Cases, 2013

Data as of 04 Mar 2013

<=14 days

>14 days

Vac

cin

e

Wil

d

Bangladesh IPH, Dhaka 194 2 0 14 107 1 70 387 97.6 9.7 70 5 0

Bhutan NIH, Bangkok 1 0 0 0 1 0 0 2 100 0 0 0 0

DPRK NPL, Pyongyang 8 0 0 0 7 1 0 22 100 0.0 0 0 0

BJMC, Ahmedabad 728 103 1 33 456 135 0 1451 99.7 4.4 10 0 0

NIV, Bangalore 378 33 1 20 240 81 3 747 99.5 5.7 0 0 0

IoS, Kolkatta 702 76 0 29 595 2 0 1385 98.6 3.2 0 0 0

KIPM, Chennai 661 58 3 78 521 1 0 1300 98.5 9.8 0 0 0

NCDC, Delhi 1126 105 3 52 797 169 0 2230 99.5 4.2 4 0 0

CRI, Kasauli 234 30 0 14 156 34 0 471 99.8 5.5 5 1 0

SGPGI, Lucknow 1436 169 23 205 830 209 0 2839 97.7 11.7 3 0 0

ERC, Mumbai 251 25 2 27 195 1 1 500 98.6 10.7 5 3 0

India Sub Total 5516 599 33 458 3790 632 4 10923 98.6 6.8 27 4 0

Biofarma, Bandung 69 0 0 8 44 7 10 138 100 10.5 0 0 0

NIHRD, Jakarta 55 0 0 4 35 11 5 108 100 10.4 0 0 0

PHL, Surabaya 54 0 0 3 44 3 4 108 100 4.3 0 0 0

Indonesia Sub Total 178 0 0 15 123 21 19 354 100.0 7.9 0 0 0

Maldives MRI, Colombo 0

Myanmar NHL, Yangon 37 0 0 2 29 6 0 74 97 4.8 0 0 0

Nepal NIH, Bangkok 50 1 0 1 30 18 0 100 100 3.1 10 1 0

Sri Lanka MRI, Colombo 1 0 0 0 1 0 0 2 100 0.0 36 3 0

Thailand NIH, Bangkok 20 0 0 2 14 4 0 40 100.0 13 0 0 0

Timor-Leste PHL, Surabaya 1 0 0 0 1 0 0 2 0.0 0 0 0 0

6006 602 33 492 4103 683 93 11906 98.6 6.9 143 13 01 Calculation based on date specimen received in laboratory subtracted from date data received in SEARO as shown in Table 1.2 Stool samples collected from contact and healthy children survey.

Positive Culture

Positive Culture +

NPEV

Received by lab

% Primary Culture Reports Within 14

days

Number received

by lab

Primary culture results from AFP cases 2013

Country Polio Laboratories

Number of AFP cases with

specimens received in Lab

AFP cases AFP specimens

Results

SEAR

NPEV Only

Negative

Pending1

India

Indonesia

% N

PE

V

Specimens from other

Page 7: Weekly AFP and VPD Update for Week 09, 2013 Data as of 04 March 2013

SEARO, New Delhi, 2013Data (NPSP) as of 01 Mar 2013

Wild Poliovirus Detected in Sewage Samples, 2010-2011

Page 8: Weekly AFP and VPD Update for Week 09, 2013 Data as of 04 March 2013

SEARO, New Delhi, 2013Data (NPSP) as of 01 Mar 2013

Wild Poliovirus Detected in Sewage Samples, 2012

Page 9: Weekly AFP and VPD Update for Week 09, 2013 Data as of 04 March 2013

SEARO, New Delhi, 2013Data (NPSP) as of 01 Mar 2013

Wild Poliovirus Detected in Sewage Samples, 2013

Page 10: Weekly AFP and VPD Update for Week 09, 2013 Data as of 04 March 2013

SEARO, New Delhi, 2013

Vaccine Preventable Diseases, SEAR, 2012-2013

Updated on 25 Feb 2013

2012

2013

Number of Outbreaks

Number of cases

Number of Outbreaks

Number of cases

Number of

Outbreaks

Number of cases

Date of last report

Number of reports expected

% Complete

% Timely

Bangladesh 62 0 62 2 13 1 1 35 0 0 0 0 0 0 0 4 0 0 0 153 14-Feb-13 1 100 100

Bhutan NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 1 0 0

DPR Korea NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 1 0 0

India NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 1 0 0

Indonesia NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 1 0 0

Maldives 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21-Feb-13 1 100 0

Myanmar 34 0 34 24 0 0 0 0 0 0 0 0 0 0 0 4 4 0 0 0 15-Feb-13 1 100 100

Nepal 6 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 31 0 14-Feb-13 1 100 100

Sri Lanka - - - - - - - - - - - - - - - - - - - - 14-Feb-13 1 100 100

Thailand 274 0 105 35 11 1 1 17 0 1 7 0 0 0 0 0 2 6 60 22-Feb-13 1 100 0

Timor-Leste NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 1 0 0

Total 376 0 202 61 24 2 2 52 0 1 7 0 0 0 0 8 6 6 91 1531 At least 5 blood samples should be collected and tested from each outbreak. 2 Adverse Events Following Immunization; Sri Lanka AEFI data do not reflect cases but events. 3 Monthly VPD and AEFI reports due to SEARO/IVD on or before 15th of each month. NR=No Report

* Total suspected outbreaks may not add to total lab confirmed outbreaks because some outbreak samples are in process with results pending and/or outbreak reports are not received from the field (investigation in process).

Number of Cases

of AEFI 2

Lab confirmed Rubella Outbreaks

Lab confirmed Mixed Outbreaks Neonatal

Tetanus(NNT)

Diphtheria PertussisEncephaliti

s

Serology +ve

Rubella

Number of Outbreaks

Number of Outbreaks

Investigated *

Number of Cases

Deaths

Lab confirmed Measles Outbreaks Country

Routine Reporting of clinically suspected measles cases

Suspected measles outbreaks Classification of Outbreaks 1 Number of CasesTimeliness and Completeness of reports

received in SEARO, 2012 3

Cases DeathsTested for serology

Serology +ve

measles

Number of Outbreaks

Number of cases

Number of Outbreaks

Number of cases

Number of

Outbreaks

Number of cases

Date of last report

Number of reports expected

% Complete

% Timely

Bangladesh 62 0 62 2 13 1 1 35 0 0 0 0 0 0 0 4 0 0 0 153 14-Feb-13 1 100 100

Bhutan NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 1 0 0

DPR Korea NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 1 0 0

India NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 1 0 0

Indonesia NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 1 0 0

Maldives 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21-Feb-13 1 100 0

Myanmar 34 0 34 24 0 0 0 0 0 0 0 0 0 0 0 4 4 0 0 0 15-Feb-13 1 100 100

Nepal 6 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 31 0 14-Feb-13 1 100 100

Sri Lanka - - - - - - - - - - - - - - - - - - - - 14-Feb-13 1 100 100

Thailand 274 0 105 35 11 1 1 17 0 1 7 0 0 0 0 0 2 6 60 22-Feb-13 1 100 0

Timor-Leste NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR NR 1 0 0

Total 376 0 202 61 24 2 2 52 0 1 7 0 0 0 0 8 6 6 91 1531 At least 5 blood samples should be collected and tested from each outbreak. 2 Adverse Events Following Immunization; Sri Lanka AEFI data do not reflect cases but events. 3 Monthly VPD and AEFI reports due to SEARO/IVD on or before 15th of each month. NR=No Report

* Total suspected outbreaks may not add to total lab confirmed outbreaks because some outbreak samples are in process with results pending and/or outbreak reports are not received from the field (investigation in process).

Number of Cases

of AEFI 2

Lab confirmed Rubella Outbreaks

Lab confirmed Mixed Outbreaks Neonatal

Tetanus(NNT)

Diphtheria PertussisEncephaliti

s

Serology +ve

Rubella

Number of Outbreaks

Number of Outbreaks

Investigated *

Number of Cases

Deaths

Lab confirmed Measles Outbreaks Country

Routine Reporting of clinically suspected measles cases

Suspected measles outbreaks Classification of Outbreaks 1 Number of CasesTimeliness and Completeness of reports

received in SEARO, 2012 3

Cases DeathsTested for serology

Serology +ve

measles

Page 11: Weekly AFP and VPD Update for Week 09, 2013 Data as of 04 March 2013

SEARO, New Delhi, 2013

Measles and Rubella Serology (IgM) Results- SEAR, 2012-2013

Updated on 18 Feb 2013

2012

2013

# % # %Bangladesh Dhaka 2553 2553 711 27.8 477 18.7 45.8 07-Feb-13Bhutan Thimphu 81 81 1 1.2 2 2.5 86.4 04-Jan-13DPR Korea Pyongyang 72 72 4 5.6 3 4.2 97.2 17-Jan-13

Ahmedabad 116 116 43 37.1 23 19.8 100.0 09-Jan-13Bangalore 168 168 57 33.9 59 35.1 100.0 01-Jan-13Bhopal 88 88 47 53.4 11 12.5 36.4 07-Jan-13Chennai 364 258 88 34.1 26 10.1 62.4 08-Feb-13Hyderabad 19 19 0 0.0 7 36.8 73.7 02-Jan-13Jaipur 67 67 40 59.7 0 0.0 89.6 01-Aug-12Kolkata 142 142 53 37.3 17 12.0 95.1 09-Jan-13Pune 35 35 32 91.4 0 0.0 62.9 14-Jan-13

999 893 360 40.3 143 16.0 79.3BANDUNG 428 428 37 8.6 252 58.9 99.5 06-Feb-13JAKARTA 2116 1672 364 21.8 401 24.0 97.7 06-Feb-13SURABAYA 1397 1315 291 22.1 333 25.3 58.9 06-Feb-13YOGYAKARTA 1885 1871 64 3.4 373 19.9 72.1 06-Feb-13

5826 5286 756 14.3 1359 25.7 79.2Maldives Male 2 573 573 0 0.0 6 1.0 99.8 09-Jan-13Myanmar Yangon 1454 1419 1181 83.2 19 1.3 28.5 08-Feb-13Nepal Kathmandu 978 978 201 20.6 308 31.5 62.2 11-Jan-13Sri Lanka Colombo 84 84 7 8.3 23 27.4 60.7 08-Jan-13Thailand Bangkok 607 590 234 39.7 71 12.0 93.9 08-Feb-13Timor-Leste Dilli - - -

13227 12529 3455 27.6 2411 19.2 67.0

Source: Reported by SEAR Measles Laboratory Network NR=No Report1 Percentages may not add to 100%; Equivocal results not included and some samples are in process with results pending. Some countries test samples for both Measles and Rubella.2 569 samples were received for Rubella testing from the hospital (routine Antenatal cases).

Indonesia Total from four labs

Total

Measles Rubella

India

India Total from six labs

Indonesia

Measles and Rubella Serology (IgM) Results - Monthly Reporting, SEAR, 2012 (data up to Feb 2013)

Country LaboratoriesNumber of

Serum Samples Received

Number Tested for Measles & Rubella

Positive Results 1

% Measles Results Reported with in 7

Days

Date of Last Report Received

in SEARO

# % # %Bangladesh Dhaka 51 41 2 4.9 6 14.6 102.4 07-Feb-13Bhutan Thimphu 2 2 0 0.0 0 0.0 100.0 06-Feb-13DPR Korea Pyongyang 6 6 0 0.0 0 0.0 100.0 13-Feb-13

Ahmedabad 5 5 0 0.0 0 0.0 100.0 08-Feb-13Bangalore 11 10 9 90.0 0 0.0 100.0 04-Feb-13Bhopal 0 0 0 - 0 - - 06-Feb-13Chennai 19 7 2 28.6 2 28.6 14.3 08-Feb-13Hyderabad 5 3 0 0.0 0 0.0 0.0 04-Feb-13Jaipur 0 0 0 - 0 - - 08-Feb-13Kolkata 5 5 0 0.0 0 0.0 100.0 14-Feb-13Pune 11 11 8 72.7 0 0.0 54.5 15-Feb-13

56 41 19 46.3 2 4.9 65.9BANDUNG 26 26 1 3.8 12 46.2 92.3 06-Feb-13JAKARTA 122 25 14 56.0 0 0.0 100.0 06-Feb-13SURABAYA 43 18 5 27.8 0 0.0 27.8 06-Feb-13YOGYAKARTA 147 147 0 0.0 0 0.0 100.0 06-Feb-13

338 216 20 9.3 12 5.6 93.1Maldives Male 2 75 75 0 0.0 1 1.3 100.0 07-Feb-13Myanmar Yangon 26 26 18 69.2 0 0.0 84.6 07-Feb-13Nepal Kathmandu 20 20 1 5.0 6 30.0 100.0 10-Feb-13Sri Lanka Colombo 0 0 0 - 0 - - 00-Jan-00Thailand Bangkok 27 27 7 25.9 6 22.2 100.0 08-Feb-13Timor-Leste Dilli - - -

601 454 67 14.8 33 7.3 93.0

Source: Reported by SEAR Measles Laboratory Network NR=No Report1 Percentages may not add to 100%; Equivocal results not included and some samples are in process with results pending. Some countries test samples for both Measles and Rubella.2 75 samples were received for Rubella testing from the hospital (routine Antenatal cases).

Indonesia Total from four labs

Total

Measles Rubella

India

India Total from six labs

Indonesia

Measles and Rubella Serology (IgM) Results - Monthly Reporting, SEAR, 2013 (data up to Jan 2013)

Country LaboratoriesNumber of

Serum Samples Received

Number Tested for Measles & Rubella

Positive Results 1

% Measles Results Reported with in 7

Days

Date of Last Report Received

in SEARO

Page 12: Weekly AFP and VPD Update for Week 09, 2013 Data as of 04 March 2013

SEARO, New Delhi, 2013

Strain Characteristics of Rotavirus Detected in Indonesia, 2011

Updated on 31 December 2012

Yogyakarta Bandung Denpasar Mataram G1P6 3 1 0 8 12G1P4 0 0 5 11 16G1P[4,8] 0 0 0 1 1G1P8 18 32 48 19 117G2P6 2 8 0 0 10G2P4 1 4 3 9 17G1P[6,8] 3 0 0 1 4G1,2P[4] 0 0 1 2 3G2P[4,8] 0 0 1 0 1G1,2P[6] 1 0 0 0 1G2,P[6,8] 0 0 0 1 1G1,untype 0 0 0 1 1

TOTAL 28 45 58 53 184

Rotavirus Sentinel Sites Total GENO TYPES