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RESPIRATORY VIRUS SURVEILLANCE REPORT Week Ending May 5, 2018 Wisconsin Department of Health Services | Division of Public Health Bureau of Communicable Diseases | Communicable Diseases Epidemiology Secon hps://www.dhs.wisconsin.gov/dph/bcd.htm | [email protected]

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Page 1: Weekly Respiratory Report Respiratory Report Description Predominant Virus of the Week: Influenza A/H3N2 CURRENT ALERTS: Influenza activity has peaked, although high activity can be

RESPIRATORY VIRUS SURVEILLANCE REPORT

Week Ending May 5, 2018

Wisconsin Department of Health Services | Division of Public Health

Bureau of Communicable Diseases | Communicable Diseases Epidemiology Section

https://www.dhs.wisconsin.gov/dph/bcd.htm | [email protected]

Page 2: Weekly Respiratory Report Respiratory Report Description Predominant Virus of the Week: Influenza A/H3N2 CURRENT ALERTS: Influenza activity has peaked, although high activity can be

Page 2

WISCONSIN DIVISION OF PUBLIC HEALTH RESPIRATORY VIRUS SURVEILLANCE REPORT WEEK ENDING MAY 5, 2018

STATE OF WISCONSIN REGION V OF US

(WI, MN, IL, MI, OH, IN)

UNITED STATES

ILI: BELOW BASELINE ILI: HIGH LEVELS ILI: MODERATE LEVELS

INFLUENZA-ASSOCIATED

PEDIATRIC DEATHS REPORTED:

INFLUENZA LIKE ILLNESS (ILI) ACTIVITY

For National US influenza surveillance statistics visit: http://www.cdc.gov/flu/weekly/

Week 18,

October 1, 2017

to present

Wisconsin 1 3

Nationwide 2 165

ILI: INSUFFICIENT DATA

AT-A-GLANCE:

Weekly Respiratory Report Description

Predominant Virus of the Week: Influenza B, followed by human

metapneumovirus and rhinovirus

CURRENT ALERTS:

Influenza B activity continues to be predominant

statewide and nationally. Influenza activity and the

number of reported outbreaks opf flu increased this

past week.

Page 3: Weekly Respiratory Report Respiratory Report Description Predominant Virus of the Week: Influenza A/H3N2 CURRENT ALERTS: Influenza activity has peaked, although high activity can be

Page 3

WISCONSIN DIVISION OF PUBLIC HEALTH RESPIRATORY VIRUS SURVEILLANCE REPORT WEEK ENDING MAY 5, 2018

Wisconsin positive influenza results and subtypes by PCR

Cumulative number of positive influenza PCR tests by subtype September 3, 2017 to present

WISCONSIN LABORATORY SURVEILLANCE

FOR RESPIRATORY VIRUSES BY PCR

0%

10%

20%

30%

40%

50%

60%

0

200

400

600

800

1,000

1,200

1,400

1,600

1,800

2,000

2,200

9/2 9/30 10/28 11/25 12/23 1/20 2/17 3/17 4/14 5/12 6/9 7/7 8/4 9/1 9/29

% P

osi

tive

by

PC

R

Nu

mb

er

of

po

siti

ve d

ete

ctio

ns

Week ending

A (unknown subtype) A (H3N2 seasonal) A (H1N1) A (H3N2v)

B (unknown subtype) B (Victoria) B (Yamagata) Influenza % positive

73% 27%

A (2009 H1N1) A (H3N2) A (Unknown) B (Victoria) B (Yamagata) B (Unknown)

Total positive (n) 194 1873 12618 12 338 5015 20050

% of total positive 1% 9% 63% 0% 2% 25% 100%

Influenza A: Influenza B:Total

Page 4: Weekly Respiratory Report Respiratory Report Description Predominant Virus of the Week: Influenza A/H3N2 CURRENT ALERTS: Influenza activity has peaked, although high activity can be

Page 4

WISCONSIN DIVISION OF PUBLIC HEALTH RESPIRATORY VIRUS SURVEILLANCE REPORT WEEK ENDING MAY 5, 2018

Trends in respiratory virus activity by PCR

WISCONSIN LABORATORY SURVEILLANCE FOR

RESPIRATORY VIRUSES BY PCR

Respiratory virus Tested Positive

(n)

Positive

(%)

Influenza A Influenza B

H3N2 2009 H1N1 Unknown Victoria Yamagata Unknown

Influenza 1222 177 14.5% 4 1 22 1 11 138

Respiratory virus Tested Positive

(n)

Positive

(%) Parainfluenza 1 Parainfluenza 2 Parainfluenza 3 Parainfluenza 4

Parainfluenza 503 8 1.6% 0 1 7 0

Respiratory virus Tested Positive

(n)

Positive

(%) CoV 229E CoV OC43 CoV NL63 CoV HKU1

Coronavirus (CoV) 249 5 2.0% 0 4 0 1

Respiratory virus Tested Positive (n) Positive (%)

RSV 708 26 3.7%

Human metapneumovirus 517 37 7.2%

Rhino-enterovirus 501 53 10.6%

Adenovirus 249 2 0.8%

Week ending on May 5, 2018

0%

5%

10%

15%

20%

25%

30%

35%

40%

45%

9/2 9/23 10/14 11/4 11/25 12/16 1/6 1/27 2/17 3/10 3/31 4/21 5/12 6/2

% P

osi

tive

by

PC

R (

3-w

ee

k m

ovi

ng

ave

rage

)

Week ending

― Influenza

― RSV― hMPV

- - Rhino-Entero― Adenovirus― Parainfluenza

- - Coronavirus

Page 5: Weekly Respiratory Report Respiratory Report Description Predominant Virus of the Week: Influenza A/H3N2 CURRENT ALERTS: Influenza activity has peaked, although high activity can be

Page 5

WISCONSIN DIVISION OF PUBLIC HEALTH RESPIRATORY VIRUS SURVEILLANCE REPORT WEEK ENDING MAY 5, 2018

WISCONSIN STATE SUMMARY

ILI activity trend analysis

Influenza and RSV trend analysis

Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI)

Tested Positive (n)

% Positive Tested Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total

473 6 75 81 17.1% 66 6 9.1% 2.1% 2.4% 3.6%

0%

5%

10%

15%

20%

25%

30%

35%

40%

45%

50%

9/2 9/23 10/14 11/4 11/25 12/16 1/6 1/27 2/17 3/10 3/31 4/21 5/12 6/2

% P

osi

tive

by

anti

gen

det

ecti

on

Week ending

RSV Influenza 3 per. Mov. Avg. (RSV) 3 per. Mov. Avg. (Influenza)

0%

1%

2%

3%

4%

5%

6%

7%

8%

9/2 9/23 10/14 11/4 11/25 12/16 1/6 1/27 2/17 3/10 3/31 4/21 5/12 6/2

Ave

rage

% IL

I

Week ending

Average % ILI Baseline Threshold 3 per. Mov. Avg. (Average % ILI)

Page 6: Weekly Respiratory Report Respiratory Report Description Predominant Virus of the Week: Influenza A/H3N2 CURRENT ALERTS: Influenza activity has peaked, although high activity can be

Page 6

WISCONSIN DIVISION OF PUBLIC HEALTH RESPIRATORY VIRUS SURVEILLANCE REPORT WEEK ENDING MAY 5, 2018

WISCONSIN STATE SUMMARY

ILI activity trend analysis by influenza season, Wisconsin

Influenza-associated hospitalizations, Wisconsin Electronic Disease Surveillance System

September 1, 2017 to present

Reported cumulative influenza-associated hospitalizations by influenza season, Wisconsin

0%

1%

2%

3%

4%

5%

6%

7%

40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20

Ave

rage

% IL

I (3

-wee

k m

ovi

ng

aver

age)

Influenza season week

― 2013-14

- - 2014-15― 2015-16

― 2016-17― 2017-18

A (2009

H1N1)

A

(H3N2)

A

(Unknown)B

Not

reported

<1 84 3 5 64 9 3 9 2 0 0

1-4 139 4 2 105 21 7 22 8 0 0

5-17 170 4 9 90 44 23 26 5 0 0

18-49 760 20 60 490 156 34 121 40 49 8

50-64 1420 40 154 798 362 66 223 70 0 0

65+ 4882 50 472 3081 1101 178 562 141 0 0

Total 7455 121 702 4628 1693 311 963 266 49 8

Postpartum

(≤6 weeks)

Age group

(years)

Total

reported

(n)

Influenza subtypeAdmitted

to ICU

Required

mechanical

ventilation

Pregnant

0

1500

3000

4500

6000

7500

7 8 9 10 11 12 13 14 15 16 17 18 19

Infl

ue

nza

-ass

oci

ate

d

ho

spit

aliz

ati

on

s, c

um

ula

tive

(n)

Influenza season week

2017-2018

2016-2017

2015-2016

2014-2015

2013-2014

Page 7: Weekly Respiratory Report Respiratory Report Description Predominant Virus of the Week: Influenza A/H3N2 CURRENT ALERTS: Influenza activity has peaked, although high activity can be

Page 7

WISCONSIN DIVISION OF PUBLIC HEALTH RESPIRATORY VIRUS SURVEILLANCE REPORT WEEK ENDING MAY 5, 2018

NORTHEASTERN REGION

ILI activity trend analysis

Influenza and RSV trend analysis

Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI)

Tested Positive (n)

% Positive Tested Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total

150 2 23 25 16.7% 21 4 19.0% 0.7% 2.6% 4.0%

0%

5%

10%

15%

20%

25%

30%

35%

40%

45%

50%

9/2 9/23 10/14 11/4 11/25 12/16 1/6 1/27 2/17 3/10 3/31 4/21 5/12 6/2

% P

osi

tive

by

anti

gen

det

ecti

on

Week ending

RSV Influenza 3 per. Mov. Avg. (RSV) 3 per. Mov. Avg. (Influenza)

0%

1%

2%

3%

4%

5%

6%

7%

8%

9/2 9/23 10/14 11/4 11/25 12/16 1/6 1/27 2/17 3/10 3/31 4/21 5/12 6/2

Ave

rage

% IL

I

Week ending

Average % ILI Baseline Threshold 3 per. Mov. Avg. (Average % ILI)

Page 8: Weekly Respiratory Report Respiratory Report Description Predominant Virus of the Week: Influenza A/H3N2 CURRENT ALERTS: Influenza activity has peaked, although high activity can be

Page 8

WISCONSIN DIVISION OF PUBLIC HEALTH RESPIRATORY VIRUS SURVEILLANCE REPORT WEEK ENDING MAY 5, 2018

NORTHWESTERN REGION

ILI activity trend analysis

Influenza and RSV trend analysis

Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI)

Tested Positive (n)

% Positive Tested Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total

76 3 14 17 22.4% 23 4 17.4% 1.0% 1.9% 3.2%

0%

5%

10%

15%

20%

25%

30%

35%

40%

45%

50%

9/2 9/23 10/14 11/4 11/25 12/16 1/6 1/27 2/17 3/10 3/31 4/21 5/12 6/2

% P

osi

tive

by

anti

gen

det

ecti

on

Week ending

RSV Influenza 3 per. Mov. Avg. (RSV) 3 per. Mov. Avg. (Influenza)

0%

3%

6%

9%

12%

9/2 9/23 10/14 11/4 11/25 12/16 1/6 1/27 2/17 3/10 3/31 4/21 5/12 6/2

Ave

rage

% IL

I

Week ending

Average % ILI Baseline Threshold 3 per. Mov. Avg. (Average % ILI)

Page 9: Weekly Respiratory Report Respiratory Report Description Predominant Virus of the Week: Influenza A/H3N2 CURRENT ALERTS: Influenza activity has peaked, although high activity can be

Page 9

WISCONSIN DIVISION OF PUBLIC HEALTH RESPIRATORY VIRUS SURVEILLANCE REPORT WEEK ENDING MAY 5, 2018

SOUTHEASTERN REGION Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI)

Tested Positive (n)

% Positive Tested Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total

215 0 32 32 14.9% 29 1 3.4% 2.9% 4.0% 6.1%

ILI activity trend analysis

Influenza and RSV trend analysis

0%

5%

10%

15%

20%

25%

30%

35%

40%

45%

50%

9/2 9/23 10/14 11/4 11/25 12/16 1/6 1/27 2/17 3/10 3/31 4/21 5/12 6/2

% P

osi

tive

by

anti

gen

det

ecti

on

Week ending

RSV Influenza 3 per. Mov. Avg. (RSV) 3 per. Mov. Avg. (Influenza)

0%

1%

2%

3%

4%

5%

6%

7%

8%

9/2 9/23 10/14 11/4 11/25 12/16 1/6 1/27 2/17 3/10 3/31 4/21 5/12 6/2

Ave

rage

% IL

I

Week ending

Average % ILI Baseline Threshold 3 per. Mov. Avg. (Average % ILI)

Page 10: Weekly Respiratory Report Respiratory Report Description Predominant Virus of the Week: Influenza A/H3N2 CURRENT ALERTS: Influenza activity has peaked, although high activity can be

Page 10

WISCONSIN DIVISION OF PUBLIC HEALTH RESPIRATORY VIRUS SURVEILLANCE REPORT WEEK ENDING MAY 5, 2018

SOUTHERN REGION Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI)

Tested

Positive (n)

% Positive Tested Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total

32 1 6 7 21.9% 1 0 0.0% 1.4% 2.1% 3.2%

ILI activity trend analysis

Influenza and RSV trend analysis

0%

5%

10%

15%

20%

25%

30%

35%

40%

45%

50%

9/2 9/23 10/14 11/4 11/25 12/16 1/6 1/27 2/17 3/10 3/31 4/21 5/12 6/2

% P

osi

tive

by

anti

gen

det

ecti

on

Week ending

RSV Influenza 3 per. Mov. Avg. (RSV) 3 per. Mov. Avg. (Influenza)

0%

1%

2%

3%

4%

5%

6%

7%

8%

9/2 9/23 10/14 11/4 11/25 12/16 1/6 1/27 2/17 3/10 3/31 4/21 5/12 6/2

Ave

rage

% IL

I

Week ending

Average % ILI Baseline Threshold 3 per. Mov. Avg. (Average % ILI)

Page 11: Weekly Respiratory Report Respiratory Report Description Predominant Virus of the Week: Influenza A/H3N2 CURRENT ALERTS: Influenza activity has peaked, although high activity can be

Page 11

WISCONSIN DIVISION OF PUBLIC HEALTH RESPIRATORY VIRUS SURVEILLANCE REPORT WEEK ENDING MAY 5, 2018

Influenza vaccine composition 2017-2018:

The trivalent vaccines for use in the 2017-2018 influenza season contain the following:

A/Michigan/45/2015 (H1N1)pdm09-like virus

A/Hong Kong/4801/2014 (H3N2)-like virus

B/Brisbane/60/2008-like virus (B/Victoria lineage)

It is recommended that quadrivalent vaccines containing two influenza B viruses contain the above three viruses

and:

B/Phuket/3073/2013-like virus (B/Yamagata lineage)

Cumulative percentage of Wisconsin residents who received 1 or more doses of

influenza vaccine, 2017-2018 influenza season

SEASONAL INFLUENZA VACCINATION

Healthy People

2020 Goal: 70%

2016-2017 Total

Vaccinated: 35.29%

This season so

far: 35.74%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Pe

rce

nt

Va

ccin

ate

d Last season, by this week, 35.20% of the WI population was vaccinated against

Influenza.

Data source: All influenza vaccination rates presented were calculated using data from the Wisconsin Immunization Registry

(numerator) and Wisconsin population estimates (denominator).

Page 12: Weekly Respiratory Report Respiratory Report Description Predominant Virus of the Week: Influenza A/H3N2 CURRENT ALERTS: Influenza activity has peaked, although high activity can be

Page 12

WISCONSIN DIVISION OF PUBLIC HEALTH RESPIRATORY VIRUS SURVEILLANCE REPORT WEEK ENDING MAY 5, 2018

Percentage of Wisconsin residents who received one or more doses of influenza

vaccine, by race and ethnicity and region, 2017-2018 influenza season

SEASONAL INFLUENZA VACCINATION

Percentage of Wisconsin residents who received one or more doses of influenza

vaccine, by age group and influenza season

Each season includes doses administered during the same time period (August 1 through May 3).

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Pe

rce

nt

of

resi

de

nts

va

ccin

ate

d

Age group

2014-2015 2015-2016 2016-2017 2017-2018

0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

American Indian

Asian

Black

White

Hispanic

Non-Hispanic

Rac

eE

thn

icit

y

Percent of residents vaccinated

Wisconsin

Northeastern

Southeastern

Southern

Western

Northern