wei z. wang, m.d. · 2020-07-11 · 1 wei z. wang, m.d. tenured professor department of surgery,...

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Wei Z. Wang, M.D. Tenured Professor Department of Surgery, Division of Plastic Surgery University of Nevada School of Medicine Las Vegas

Contact Information 2040 W. Charleston Blvd., Suite 302, Las Vegas, NV 89102 Office Phone: 702-671-2282 Office Fax: 702-671-2245 E-Mail Address: [email protected]

[email protected] Citizenship USA Certificate 1993----- Vice-Director Surgeon (Chief), Orthopaedic Department, Ren Ji

Hospital, Shanghai Jiao Tong University, Shanghai, China Education 1985-1988: Jiao Tong University, Shanghai, China, Master Degree of Medicine (Major: Orthopaedic Surgery) 1971-1975: Jiao Tong University, Shanghai, China, Bachelor Degree of

Medicine and equivalent to MD (Major: Medicine) Research Interest Ischemia Reperfusion Injury Adipose Stem Cell Post-Graduate Training 1994-1997: Postdoctoral Research Associate. Center for Applied Microcirculatory

Research, University of Louisville, Louisville

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1990-1993: Clinical Fellow. Christine M. Kleinert Institute for Hand and

Microsurgery, Louisville 1980-1985: Orthopaedic Residency, Ren Ji Hospital, Affiliated with Jiao Tong

University, Shanghai 1975-1980: Surgical Residency, Ren Ji Hospital, Affiliated with Jiao Tong

University, Shanghai Work History 2013-------- Tenured Professor. Department of Surgery, Division of

Plastic Surgery, University of Nevada School of Medicine, Las Vegas

2007---2013: Associate Professor with Tenured. Department of Surgery,

Division of Plastic Surgery, University of Nevada School of Medicine, Las Vegas

2000---2006: Associate Professor. Department of Surgery, Division of

Plastic Surgery, University of Nevada School of Medicine, Las Vegas

1997-2000: Assistant Professor. Center for Applied Microcirculatory

Research, University of Louisville, Louisville 1994-1997: Postdoctoral Research Associate. Center for Applied

Microcirculatory Research, University of Louisville, Louisville 1993-1994: Vice-Director Surgeon (Chief) and Associate Professor in

Orthopaedic Surgery, Ren Ji Hospital, Jiao Tong University, Shanghai

1990-1993: Clinic Fellow. Christine M. Kleinert Institute for Hand and

Microsurgery, Louisville 1988-1990: Attending Surgeon, Orthopaedic Surgery, Ren Ji Hospital, Jiao

Tong University, Shanghai 1980-1985: Resident in Orthopaedic Surgery, Ren Ji Hospital, Jiao Tong

University, Shanghai 1975-1980: Resident in General Surgery, Ren Ji Hospital, Jiao Tong

University, Shanghai

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Selected Peer-Reviewed Publications (* the correspondent author) 1. Siemionow M, Wang WZ, Anderson GL and Firrell JC*. Leukocyte-

endothelial interaction capillary perfusion in ischemia/reperfusion of the rat cremaster muscle. Microcirc. Endoth. Lymphatics, Vol. 7:187-197, 1991

2. Tsai TM and Wang WZ. Invited Chapter. Vascular Joint Transfers. Hand Clinics. Vol. 8(3), 525-536, 1992.

3. Wang WZ*, Anderson GL and Firrell J. Arteriole constriction following ischemia in denervated skeletal muscle. J Reconstruc Microsurg Vol. 11 (2): 99-106, 1995

4. Wang WZ*, Anderson GL, Maldonado C, and Barker J. Attenuation of vasospasm and capillary no-reflow by ischemic preconditioning in skeletal muscle. Microsurgery. Vol. 17, No. 6, 324-329, 1996

5. Peter FW*, Franken RJRM, Wang WZ, et al. Tissue and anastomotic protection in microvascular surgery: the effect of low dose aspirin. Surg. Forum 47: 744-746, 1996

6. Franken RJRM*, Peter FW, Wang WZ, et al. The anatomy of the feeding blood vessels of the cremaster muscle in the rat. Microsurgery. Vol. 17, No. 7, 402-408, 1996

7. Wang WZ* and Tsai TM. Outcome of digital nerve injuries in adults. J Hand Surg 21A, 138-143, 1996

8. Peter FW*, Franken RJRM, Wang WZ, et al. The effect of low dose aspirin on thrombus formation at arterial and venous microanastomoses ans on the tissue micrcirculation. Plast Reconstruc Surg, Vol. 99, No. 4, 1112-1121, 1997

9. Wang WZ*, Anderson GL, Acland RD and Barker J. Endothelin-1 does not contribute to ischemia/reperfusion-induced vasoconstriction in skeletal muscle. J Reconstruc Microsurg, Vol. 13, No. 6, 439-447, 1997

10. Wang WZ*, Anderson GL, Fleming JT, Peter FW, Franken RJ, Acland RD and Barker J. Lack of nitric oxide contributes to vasospasm during ischemia/reperfusion injury. Plast Reconstruc Surg, Vol. 99, No. 4, 1099-1108, 1997

11. Wang WZ*, Anderson GL. Firrell J and Tsai TM. Ischemic preconditioning vs. intermittent reperfusion to improve blood flow to a vascular isolated skeletal muscle flap of rats. J Trauma. 45 (5): 953-959, 1998

12. Peter FW*, Schuschke DA, Wang WZ, et al. Do leukocytes contribute to impaired microcircular tissue perfusion after arterial repair? Microsurgery. 18:23-28, 1998

13. Franken RJPM, Werker PMN, Peter FW, Overgoor MLE, Wang WZ, Anderson Gl, Schuschke DA, Banis JC, Kon M, and Barker JH*. Microcirculatory changes following different temperature washouts in a free flap model. Microsurgery 19: 214-222, 1999

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14. Wang WZ*, Tsai TM and Anderson GL. Late preconditioning protection is evident in the microcirculation of skeletal muscle. J Orthop Res, 17(4):571-577, 1999

15. Wang WZ*, Guo SZ, Tsai TM, Anderson GL and Miller FN. Platelet-activating factor contributes to postischemic vasospasm. J Surg Res, 89, 139-146, 2000

16. Wang WZ*, Guo SZ, Tsai TM, Anderson GL and Miller FN. The initiation of microvascular protection by nitric oxide in the late preconditioning. J Reconstruc Microsurg 16(8): 621-628, 2000

17. Wang WZ*, Guo SZ, Tsai TM, Anderson GL and Miller FN. The initiating factors of late preconditioning in the microcirculation of skeletal muscle. J Surg Res. 99, 92-99, 2001

18. Wang WZ* and Anderson GL. Invited Chapter. Intervention Approaches against I/R-induced arterial insufficiency in reconstructive microsurgery. Hand Clinics 17(3): 357-369, 2001

19. Wang WZ*, Fang XH, Stephenson LL, Anderson GL, Miller FN, Khiabani KT and Zamboni WA. Role of PKC in microvascular protection induced by late preconditioning. J Surg Res. 106(1): 166-172, 2002

20. Wang WZ*, Jones S, Stephenson LL, Khiabani KT and Zamboni WA. Microvascular protection induced by late preconditioning abolished in STZ-Induced diabetic rats. J Reconstruc Microsurg, 18(8):389-396, 2002

21. Wang WZ*, Fang XH, Stephenson LL, Khiabani KT and Zamboni WA. NOSs upregulation attenuates vascular endothelial dysfunction in the late phase of ischemic preconditioning in skeletal muscle. J Orthop Res, 22(3): 578-585, 2004.

22. Wang WZ*, Fang XH, Stephenson LL, Khiabani KT and Zamboni WA. Ischemic preconditioning-induced microvascular protection at a distance. J Reconstruc Microsurg, 20(2): 61-67, 2004.

23. Khiabani KT, Stephenson LL, Gabriel A, Nataraj C, Wang WZ and Zamboni WA*. A Quantitative Method for Determining Polarization of

Neutrophil Adhesion Molecules Associated with Ischemia Reperfusion. Plast Reconstruc Surg, 114(7): 1846-1850, 2004.

24. Wang WZ*, Fang XH, Stephenson LL, Khiabani KT and Zamboni WA. Acute microvascular action of vascular endothelial growth factor in skeletal muscle ischemia/reperfusion injury. Plast Reconstruc Surg. 115:1355-1365, 2005.

25. Wang WZ*, Fang XH, Stephenson LL, Baynosa RC, Khiabani KT and Zamboni WA. Microcirculatory effects of melatonin in rat skeletal muscle after prolonged ischemia. J Pineal Res, 39:57-65, 2005.

26. Wang WZ*, Fang XH, Stephenson LL, Khiabani KT and Zamboni WA. Melatonin reduces I/R-induced superoxide generation in arterial wall and cell death in skeletal ,muscle. J Pineal Res, 41(3): 255-260, 2006.

27. Wang WZ and Zamboni WA*. Discussion for PDGF gene therapy enhances expression of VEGF and bFGF genes and activates NF-KB gene in signal pathways in ischemic flaps. XT Wang, PY Liu and JB Tang. Plast Reconstruc Surg, 117(1): 138-139, 2006.

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28. Wang WZ*, Fang XH, Stephenson LL, Khiabani KT and Zamboni WA. Microcirculatory effects of BH4 in rat skeletal muscle after prolonged ischemia. Microsurgery, 27: 200-205, 2007.

29. Wang WZ*, Fang XH, Stephenson LL, Khiabani KT and Zamboni WA. Ischemia/reperfusion-induced necrosis and apoptosis in the cells isolated from rat skeletal muscle. J Orthop Res, 26: 351-356, 2008.

30. Khiabani, KT, Bellister SA, Skaggs SS, Stephenson LS, Nataraj C, Wang WZ and Zamboni WA*. Reperfusion induced neutrophil CD18 Polariztion: Effect of hyperbaric oxygen, J Surg Res, 150: 11-16, 2008

31. Wang WZ.* Invited Review Paper. Investigation of Reperfusion Injury and Ischemic Preconditioning in Microsurgry. Microsurgery, 29:72-79, 2009.

32. Wang WZ*, Fang XH, Stephenson LL, Khiabani KT and Zamboni WA. Ischemia-Reperfusion-induced apoptotic endothelial cells isolated from rat skeletal muscle. Plast Reconstruc Surg, 123 (Suppl.): 131s-138s, 2009.

33. Baynosa, RC., Browder, LK., Jones, SR., Oliver, JA., Van der Harten, CA., Stephenson, LL., Wang, WZ., Khiabani, KT., Zamboni*, WA: Evaluation of Artificial Dermis Neovascularization in an Avascular Wound. J Reconstr Microsurg. 25(7): 405-410, 2009.

34. Jones SR, Carpin KM, Woodward, SM, Khiabani KT, Stephenson LL, Wang WZ, Zamboni WA*. Hyperbaric Oxygen Inhibits Ischemia-Reperfusion Induced Neutrophil CD18 Polarization by a Nitric Oxide Mechanism. Plast Reconstr Surg 126(2):403-411, 2010

35. Wang WZ*, Fang XH, Stephenson LL, Khiabani KT and Zamboni WA. Melatonin Attenuates I/R-induced Mitochondrial Dysfunction in Skeletal Muscle. J Surg Res. 171 (1): 108-113. 2011.

36. Wang WZ*, Baynosa, RC., Zamboni WA. Update on I/R Injury for Plastic Surgeon (2011). Plast Reconstruc Surg, 128(6): 685e-92e, 2011.

37. Wang WZ*, Fang XH, Stephenson LL, Zhang X, Williams SJ, Baynosa RC, Khiabani KT and Zamboni WA. Nitrite Attenuates I/R-induced Microcirculatory Alterations and Mitochondrial Dysfunction in the Microvasculature of Skeletal Muscle. Plast Reconstruc Surg, 128(4):279e-87e, 2011.

39. Wang WZ*, Baynosa, RC., Zamboni WA. Therapeutic Interventions against Reperfusion Injury in Skeletal Muscle. J Surg Res. 171: 175-182, 2011.

40. Brosious JP, Tsuda ST, Menezes JM, Baynosa RC, Stephenson LL, Mohsin AG, Wang WZ, Zamboni WA.* Objective Evaluation of Skill Acquisition in Novice Microsurgeons. J Reconstruc Microsurg 8: 539-542, 2012.

41. Wang WZ*, Fang XH, Stephenson LL, Williams SJ, Baynosa RC, Wong N, Khiabani KT and Zamboni WA. Analysis for Apoptosis and Necrosis on Adipocytes, Stromal Vascular Fraction and Adipose-derived Stem Cells in Human Lipoaspirates after Liposuction. Plast Reconstruc Surg, 131 (1): 77e-85e, 2013.

42. Wang WZ*, Fang XH, Stephenson LL, Williams SJ, Baynosa RC, Wong N, Khiabani KT and Zamboni WA. The Effect of Lipoaspirates

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Cryopreservation on Adipose-derived Stem Cells. Aesthetic Surg J, 33(7): 1046-1055, 2013.

43. Baynosa RC, Naig AL, Murphy PS, Fang XH, Stephenson LL, Khiabani KT, Wang WZ and Zamboni WA.* The Effect of Hyperbaric Oxygen on NOS Activity and Expression in IR Injury Journal of Surgical Research. J Surg Res, 2013 Jul;183 (1):355-61, 2013.

44. AG Silver, R Baynosa, R Mahabir, W Wang, W Zamboni, K Khiabani*. Acral myxoinflammatory fibroblastic sarcoma: A case report and literature review. Can J of Plast Surg, 21 (2): 92-94, 2013.

45. Brosious, J.P., Wong, N., Fowler, G., Stephenson, L.L., Wang, W.Z., Zamboni, W.A., and Taghipour-Khiabani, K.* Evaluation of AlloMax Acellular Dermal Matrix for Objective Collagen Deposition. J Reconstr Microsurg 30(1): 31-34, 2014.

46, Wang WZ*, Fang XH, Stephenson LL, Williams SJ, Baynosa RC, Khiabani KT and Zamboni WA. Lidocaine-induced ASC Apoptosis (Tumescent vs. Local Anesthesia Liposuction). Aesthetic Plast Surg, 2014, Epub ahead of print. DOI: 10.1007/s00266-014-0387-2.

47. Wang WZ*, Fang XH, Stephenson LL, Williams SJ, Baynosa RC, Jaeger N, Khiabani KT and Zamboni WA. The impact of short-term refrigeration of lipoaspirate on adipose-derived stem cells and adipocytes. J Plast Reconstruc Aesthetic Surg, 2014; Epub ahead of print. DOI:10.1016/j.bjps.2014.08.070

48. Wang WZ*, Fang XH, Williams SJ, Stephenson LL, Baynosa RC, Khiabani KT and Zamboni WA. Elimination of Reperfusion-induced Microcirculatory Alterations in-vivo by ASC Supernatant without ASC Cell. Plast Reconstruc Surg, In-Press.

Lectures and Presentations (National & International Conferences only)

“The Impact of Cold Storage on Human Lipoaspirates on Adipose-derived Stem Cells and Adipocytes” Wang WZ*, Fang XH, Stephenson LL, Williams SJ, Baynosa RC, Wong N, Khiabani KT and Zamboni WA. 11h Annual Meeting of International Federation for Adipose Therapeutics and Science (IFATS) November 21-24, 2013, New York, NY. “Development of a Standardized Microsurgical Skill Curriculum in Novice Microsurgeons”. N Jaeger, JP Brosious, N Wong, LL Stephenson, AG Mohsin, WZ Wang, JM Menezes, ST Tsuda, WA Zamboni, RC Baynosa. World Society for Reconstructive Microsurgery 2013, Chicago Invited Guest Speaker. “ASC Apoptosis in Human Lipoaspirates”. The Third World Congress for Plastic Surgeons of Chinese Descent. Xi’an, China, Oct 12-14, 2012.

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“Apoptosis and Necrosis of ASC Sub-populations in Fresh Human Lipoaspirates” Wang WZ*, Fang XH, Stephenson LL, Williams SJ, Baynosa RC, Wong N, Khiabani KT and Zamboni WA. 8th Stem Cell Summit April 19-20, 2012, Boston, MA “The Effect of Cryopreservation on Human Adipose-derived Stem Cells” Wang WZ*, Fang XH, Stephenson LL, Williams SJ, Baynosa RC, Wong N, Khiabani KT and Zamboni WA. 8th Stem Cell Summit April 19-20, 2012, Boston, MA “Nitrite Attenuates I/R-induced Microcirculatory Alterations and Mitochondrial Dysfunction in the Microvasculature of Skeletal Muscle” Wang WZ*, Fang XH, Stephenson LL, Zhang X, Williams SJ, Baynosa RC, Khiabani KT and Zamboni WA. Annual Scientific Meeting of ASRM, Las Vegas, Nevada, January 2012. “Objective Evaluation of skill acquisition in novice microsurgeons” JP Brosious, ST Tsuda, JM Menezes, LL Stephenson, MT, RC Baynosa, WZ Wang,WA Zamboni*. Annual Scientific Meeting of ASRM, Las Vegas, Nevada, January 2012. “The Efficacy of Melatonin on I/R-induced Mitochondrial Dysfunction in Skeletal Muscle in-vivo”. Wang WZ*, Fang XH, Stephenson LL, Zhang X, Khiabani KT and Zamboni WA. Presented at the ASRM 2011 Annual Meeting, Cancun, Mexico, January 2011 “Role of Rac Protein in Ischemia-Reperfusion Treated with Hyperbaric Oxygen”. JP Brosious, LL Stephenson, WZ Wang, WA Zamboni*. Presented at the 56th Annual Scientific Meeting of the Plastic Surgery Research Council, Louisville, KY, 2011. “J Role of Rac Protein in Ischemia-Reperfusion Treated with Hyperbaric Oxygen”. P Brosious, LL Stephenson, WZ Wang, WA Zamboni*. Presented at the 5th Annual Resident Research Day, UNSOM, Las Vegas, June 3, 2011 “Gene Expression Analysis in Ischemia Reperfusion Injury Treated with Hyperbaric Oxygen Reveals Retinol Saturase Involvement”. RL Stutman,SJ Williams, LL Stephenson, WZ Wang, WA Zamboni, M.D.2010 Annual Scientific Meeting of ASRM, Boca Raton, Florida, January 2010. “Ischemia/Reperfusion-Induced Apoptosis In Vascular Cells Proceeds Through The Mitochondrial-Dependent Pathway” CJ Allen, XH Fang, LL Stephenson, X Zhang, KT Khiabani, WA Zamboni, WZ Wang. American College of Surgeons, 95th Annual Clinical Congress Medical Student Program, Division of Education, Chicago, IL. October 11-15, 2009 “Melatonin attenuates the depletion of mitochondrial cytochrome c in the cells of rat skeletal muscle after ischemia/reperfusion in vivo” presented at 54th Annual

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Meeting of the Plastic Surgery Research Council, May 27-30, 2009, Pittsburgh, Pennsylvania. “I/R-induced Apoptosis and Necrosis in the Endothelial Cells from Muscle’s Microcirculature” Invited Speaker at First Joint Conference Chinese Society of Microsurgery and American Society for Reconstructive Microsurgery. Oct 20-22, 2008, Shanghai, China. Invited Guest Speaker. “Ischemia/Reperfusion Injuey”. At 1st World Congress for Plastic Surgeons of Chinese Descent. Oct. 10-12, Beijing, China. “I/R-induced Apoptotic Endothelial Cells Isolated from Skeletal Muscle vs. from Peripheral Blood” 53th Annual Meeting of the Plastic Surgery Research Council, May 29-31, 2008, Springfield, Illinois. “Neutrophil Apoptosis in Ischemia Reperfusion Injury and the Effect of Hyperbaric Oxygen” 53th Annual Meeting of the Plastic Surgery Research Council, May 29-31, 2008, Springfield, Illinois. “Ischemia/reperfusion-induced Apoptotic Endothelial Cells Isolated from Rat Skeletal Muscle” Annual Meeting of American Society of Reconstrictive Microsurgery, Jan 11-13, 2008, Los Angle, CA. “Ischemia/reperfusion-induced apoptosis in skeletal muscle”. 52th Annual Meeting of the Plastic Surgery Research Council, June 20-23, 2007, Stanford University, Stanford, CA “The effect of hyperbaric oxygen on eNOS proten expression in ischemia-reperfusion injury”. 52th Annual Meeting of the Plastic Surgery Research Council, June 20-23, 2007, Stanford University, Stanford, CA “Melatonin Reduces Superoxide Generation in the Arterial Wall and Cell Death in the Muscle after Ischemia. 51th Annual Meeting of the Plastic Surgery Research Council, May 17-20, 2006, Dana Point, CA. “VEGF as a molecular signal in the hyperbaric oxygen pathway” 51th Annual Meeting of the Plastic Surgery Research Council, May 17-20, 2006, Dana Point, CA. “Engineering cartilage- and bone-like tissue in vitro using rabbit adipose-derived stromal cells and biodegradable poly-lactic-glycolic acid scaffolds” 51th Annual Meeting of the Plastic Surgery Research Council, May 17-20, 2006, Dana Point, CA.

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“The Deficiency of BH4 is Responsible for Reduced NOS Activity, Tissue Viability and Endothelial Dysfunction in Skeletal Muscle after Ischemia/Reperfusion” 14th Kleinert Society Clinical Reunion, Jun 16-19, 2005, Louisville, KY “Lack of BH4 Contributes to Endothelial Dysfunction and Degradation of cNOS Activity in Skeletal Muscle after Prolonged Ischemia”. 50th Annual Meeting of the Plastic Surgery Research Council, May 18-21, 2005, Toronto, Ontario. “Chondrogenic Potential of Rat Adipose Tissue” 50th Annual Meeting of the Plastic Surgery Research Council, May 18-21, 2005, Toronto, Ontario. “The Effect of Vascular Endothelial Growth Factor on Leukocyte Adhesion in Ischemia-Reperfusion Injury” 50th Annual Meeting of the Plastic Surgery Research Council, May 18-21, 2005, Toronto, Ontario. “The Effect of Hyperbaric Oxygen on Nitric Oxide Synthase and Vascular Endothelial Growth Factor Expression in Ischemia Reperfusion Injury” Aech Surg 199(supl): S65, 2004. The Effect of Vascular Endothelial Growth Factor (VEGF) on Neutrophil CD18/11b Polarization and Adhesion in IR Injury. Undersea and Hyperbaric Medicine 32(supl), 2005. Las Vegas. Hyperbaric Oxygen Upregulates VEGF Through a HIF-1 Pathway. Undersea and Hyperbaric Medicine 32(supl), 2005. Las Vegas. The Effect of Hyperbaric Oxygen on NOS Activity and Transcription in Ischemia Reperfusion Injury. Undersea and Hyperbaric Medicine 32(supl), 2005. Las Vegas. “Microvascular Effects of Melatonin in Skeletal Muscle”. Annual Meeting of American Society of Reconstrictive Microsurgery, Jan 15-18, 2005, Purto Rico. “Acute Microvascular Action of Vascular Endothelial Growth Factor in Skeletal Muscle Ischemia/Reperfusion Injury”. 49th Annual Meeting of the Plastic Surgery Research Council, to be held June 9-12, 2004 in Ann Arbor, Michigan. “The effect of hyperbaric oxygen on nitric oxide synthase and vascular endothelial growth factor expression in ischemia reperfusion injury”. 49th Annual Meeting of the Plastic Surgery Research Council, to be held June 9-12, 2004 in Ann Arbor, Michigan. “Ischemia reperfusion: NOS inhibition reverses the effect of HBO on neutrophil adhesion in vivo “. 49th Annual Meeting of the Plastic Surgery Research Council, to be held June 9-12, 2004 in Ann Arbor, Michigan.

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“The effect of isoform-selective nitric oxide synthase inhibitors on PMN CD18/11b polarization in ischemia-reperfusion injury”. 49th Annual Meeting of the Plastic Surgery Research Council, to be held June 9-12, 2004 in Ann Arbor, Michigan. Invited Guest Speaker. “Ischemia reperfusion injury”. Distinguish Lecture for 9th Congress of Chinese Medical Association for Surgery of the Hand. May 22-27, 2004, Shanghai Invited Guest Speaker. “Ischemia reperfusion injury in Reconstrictive Microsurgery”. At 7th Hand Forum, Apr 9-11, 2004, Las Vegas. “Adenosine is not the initiating factor for remote ischemic preconditioning”. Annual Meeting of American Society of Reconstrictive Microsurgery, Jan 17-20, 2004, Palms Springs, CA. "Nitric Oxide Synthases upregulation in the Late Phase of Ischemic Preconditioning in the Skeletal Muscle", for presentation at the 48th Annual Meeting of the Plastic Surgery Research Council, to be held April 23-26, 2003, Las Vegas. "Microcirculatory Protection of Skeletal Muscle in Remote Preconditioning", for presentation at the 48th Annual Meeting of the Plastic Surgery Research Council, to be held April 23-26, 2003, Las Vegas. “Nitric Oxide Sythases Expression in the Late Phase of Ischemic or Adenosine Preconditioning in the Skeletal Muscle” American Society of Reconstrictive Microsurgery, Hawaii, Jan 12-15, 2003. “HBO Inhibits IR Induced Neutrophil CD 18 Polarization by a Nitric Oxide Mechanism” the 47th Annual Meeting of the Plastic Surgery Research Council, Boston, Massachusetts, April, 2002 “Late preconditioning in the microcirculation of skeletal muscle of STZ-induced diabetic rats” the 47th Annual Meeting of the Plastic Surgery Research Council, Boston, Massachusetts, April, 2002 “Role of PKC in Microvascular Protection in the Late Phase of Ischemic- or Adenosine Preconditioning in Skeletal Muscle” the 47th Annual Meeting of the Plastic Surgery Research Council, Boston, Massachusetts, April, 2002 “PKC Contributes to Microvascular Protection Induced by Delayed Ischemic Preconditioning in Skeletal Muscle” American Society of Reconstrictive Microsurgery, Jan 12-15, 2002, Cancun, Mexico, Jan. 2002.

“Late Preconditioning Attenuates Vascular Endothelium Dysfunction after Prolonged Ischemia/Reperfusion in Skeletal Muscle” Inaugural Congress of the

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World Society for Reconstructive Microsurgery. Taipei, Taiwan, Oct. 2001 “The Initiating Factors of Late Preconditioning in Skeletal Muscle” 46th Annual Meeting of The Plastic Surgery Research Council, Milwaukee, Wisconsin, April, 2001 “The Initiating Factor of Late Preconditioning” Nevada Biomedical Research and Education Conference. Las Vegas, March, 2001 “The Role of PAF on Reperfusion-Induced Endothelium Dysfunction” Nevada Biomedical Research and Education Conference. Las Vegas, March, 2001 “The initiation of microvascular protection by nitric oxide in the late preconditioning” 47th Annual Conference of the Microcirculatory Society, inc. San Diego. 2000 “Platelet-activating factor contributes to postischemic vasospasm” 47th Annual Conference of the Microcirculatory Society, inc. San Diego. 2000 “Late preconditioning protection is evident in the microcirculation of skeletal muscle” 46th Annual Conference of the Microcirculatory Society, inc. Washington, DC. 1999 “ischemic preconditioning vs. intermittent reperfusion to improve flow to a vascular isolated skeletal muscle flap of rats”. 13th annual meeting, American Society of Reconstructive Microsurgery, Scottsdale, Arizona, Jan 3-7, 1998 “ischemic preconditioning vs. intermittent reperfusion to improve flow to a vascular isolated skeletal muscle flap of rats”. Vascular Biology’98, San Francisco, CA. 1998 “Attenuation of vasospasm and capillary no-reflow by ischemic preconditioning in skeletal muscle”. Vascular Biology’97, New Orleans, Louisiana, April 3-6, 1997 “Role of nitric oxide in mediating the delay phenomenon” 42th annual meeting, Plastic Surgery Research Council. Galveston, Texas. Feb. 26-March 1, 1997 “Endothelin-1 does not contricbute to ischemia/reperfusion-induced vasoconstriction in skeletal muscle”. 12 th annual meeting, American Society of Reconstructive Microsurgery. Boca Raton, FL. Jan. 1-15, 1997 “ The effect of low dose aspirin on thrombus formation at arterial and venous microanastomoses ans on the tissue micrcirculation”. 41th annual meeting of Plastic Surgery Research Council. St. Louis, MO, June 1-4, 1996

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“ The effect of low dose aspirin on thrombus formation at arterial and venous microanastomoses ans on the tissue micrcirculation”. 6th World Congress for Microcirculation. Munich, Germany. August 25-30, 1996 “Local infusion of nitricprusside but not acetylcholine attenuates vasospasm and no-reflow associated with prolonged warm ischemia-reperfusion in the vascular isolated cremaster muscle”. 41th Annual Meeting of the Plastic Surgery Research Council. New York, New York. 1995 “Microcirculatory changes following different temperature washouts in free flap muscle” 15th Congress of European Society for Surgical Research, Amsterdam, 1995 “Local infusion of nitrioprusside but not acetylcholine attenuates vasospasm and no-reflow associated with prolonged warm ischemia-reperfusion in the vascular isolated cremaster muscle”. 42th Annual Meeting of the Microcirculatory Society, inc. Atlanta, GA. 1995 “Outcome of digital nerve injuries in adults” Annual Meeting. American Society for Hand Surgery. St Louis, 1993 “Denervation enhances vessel reactivity following ischemia in skeletal muscle” 8th Annual Meeting, American Society for Reconstructive Microsurgery. Scottsdale, Arizona, 1992 “Neutrophil number does not influence capillary perfusion in ischemia reperfusion” 8th Annual Meeting. American Society for Reconstructive Microsurgery. Scottsdale, Arizona, 1992 Teaching: Microsurgery Skill Training Course: for residents in Department Surgery and medical students in UNSOM. Lecturer and Moderator: for Educational Conference for Plastic Surgery Resident Program in UNSOM. Clinical Anatomy for medical students of UNSOM in Reno Grand Round, Department Surgery (I/R injury in skeletal muscle). Grand Round, Department Surgery (Medical Statistical Analysis). Grand Round, Department Surgery (Splinting for Fracture and Dislocation). Lecture and Workshop for Surgery Clerkship (Splinting and Casting).

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Workshop of Suture Methods of Surgery for Surgery Clerkship

Consultant for Plastic Surgery Resident’s Research Projects

Mentor for UNR Medical Student Summer Research Project

Professional Service: Formal Member of Editorial Board of Annals of Plastic Surgery Formal Member of Editorial Board of Journal of Reconstructive Microsurgery Guest Reviewer: American Journal of Physiology Journal of Biomechanics

Plastic and Reconstructive Surgery Committees: Member of Program Committee for (2010-2011) American Society Reconstructive Microsurgery. Member of Search Committee (2010-2011) for Associate Dean for Graduate Medical Education, University of Nevada School of Medicine Member of Search Committee (2011) for UMC Clinical Librarian, University of Nevada School of Medicine Member of curriculum reform for 1st year medical students, block 4 musculoskeletal and integument (2011) RIB Application: Approved (Feb, 2011). “The Adipose-derived Stem Cell in Human Lipoaspirate for Fat Grafting”. Research Grants:

Agency: National Institutes of Health (NIH, RO1) Grant Title: "The Effect of ASCs on the Angiogenesis and I/R-induced

Endothelial Apoptosis in Muscle’s Microcirculation” Position: Principal Investigator Status: Rejected: (10/13)

Agency: Department of Surgery, UNSOM Grant Title: "The effect of fresh SVF vs. cultured ASCs on the

Angiogenesis and I/R-induced Endothelial Apoptosis in Muscle’s Microcirculation”

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Position: Principal Investigator Status: Funded: (6/13 - 5/14)

Agency: DHS/UNSOM Faculty Development Support Grant Title: “Impact of Liposuction Techniques on ASC Survival"


Agency: Department of Surgery, UNSOM Grant Title: "Investigation of adipose-derived stem cells in human

lipoaspirate” Position: Principal Investigator Status: Funded: (6/12 - 5/13)

Agency: Department of Surgery, UNSOM Grant Title: "Nitrite Intervention in the Ischemic Microcirculation of

Skeletal Muscle” Position: Principal Investigator Status: Funded: (6/11 - 5/12)

Agency: Department of the Army Grant Title: "Nitrite Intervention in the Microcirculation of Ischemic

Muscle” Position: Principal Investigator

Status: Rejected: (10/09) Agency: National Institutes of Health (NIH, RO1) Grant Title: "Nitrite Intervention in the ischemic microcirculation”

Position: Principal Investigator Status: Rejected: (10/08)

Agency: National Institutes of Health (NIH, RO1) Grant Title: "Melatonin-induced Endothelial Protection in muscle’s

microvasculature" Position: Principal Investigator Status: Rejected: (10/07)

Agency: American Heart Association (AHA) Grant Title: "The Mechanism of Melatonin-induced Protection Against

I/R" Position: Principal Investigator Status: Rejected: (7/06)

Agency: Aircast Foundation Grant Title: "VEGF-induced Microvascular Protection"

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Agency: American Heart Association (AHA) Grant Title: "The Mechanism of Remote Preconditioning"


Agency: National Institutes of Health (NIH, RO1) Grant Title: "Remote Preconditioning"


Agency: National Institutes of Health (NIH, RO1) Grant Title: "Microcirculatory protection in late preconditioning"


Agency: American Heart Association (AHA) Grant Title: "Late Preconditioning in Microcirculation"

Position: Principal Investigator Status: Funded: (7/00-6/02) Agency: Orthopaedic Research Education Foundation (OREF)

Grant Title: "The role of platelet-activating factor in ischemia/reperfusion injury of skeletal muscle"


Agency: Christine M. Kleinert Institute for Hand and Microsurgery Grant Title: "I/R injury in skeletal muscle"


Agency: Jewish Hospital Foundation Grant Title: "The role of NO in replantation and free flap failure”

Position: Co-Investigator to Robert D. Acland, M.D. Status: Founded: (3/95 - 2/97)

wei z. wang, m.d. · 2020-07-11 · 1 wei z. wang, m.d. tenured professor department of surgery,...

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