what ms - drug therapy
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About Multiple Sclerosis
Multiple Sclerosis (MS) is a disease of the central nervous
system (CNS: the brain and spinal cord) that most commonly
affects young adults. Sclerosis means hardening; multiple
sclerosis means that there are multiple area of hardened tissue
in the brain and spinal cord due to scarring. Get more detail on
our blog site .
Drug Therapy in MS
In the treatment of MS, medication is only a part of the management with many supportive
measures that are equally important. The management of MS falls into three broad categories
Drugs to treat attacks (immediate treatment for a relapse):
l Corticosteroids are mainly used to reduce the inflammation during a relapse.3 Not all relapses
require hospitalisation. Some may be treated with oral corticosteroid therapy while more
severe attacks may need injectable corticosteroids.
l Plasma exchange (plasmapheresis) is a procedure that removes some blood from your body
and mechanically separates your blood cells from your plasma. The blood cells are then mixed
with a replacement solution and return the blood to the body. Plasma exchange in rare
situations may be used to help combat severe symptoms of multiple sclerosis relapses in
people who arent responding to intravenous steroids.4,5
Starting treatment early and staying on treatment can make a real difference in managing your
MS symptoms and slowing the progression of your disease. In fact, many MS treatments have
been shown to reduce the risk of having a relapse and slow the progression of disability. MS
therapy has several goals:
l Reducing the number of relapses
l Slowing down disability progression
l Reducing the number of brain lesions
l Reducing the rate of brain shrinkage
There are numerous therapy options available to you in India which may help you manage MS
more effectively:
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l Beta interferons.
l Glatiramer acetate.
l Natalizumab.
l Mitoxantrone.
Be sure to work with your doctor to choose a treatment plan that works best for your lifestyle and
the specific type of MS you have. The success of your MS treatment can depend on your
commitment to taking your treatment consistently as prescribed. Choosing the option thats right
for you may help.
Drugs to treat MS symptoms
l Medications to reduce fatigue.
l Muscle relaxants for spasticity
l Other medications. Medications also may be prescribed for depression, pain, and bladder or
bowel control problems that may be associated with multiple sclerosis.
Please consult your doctor to choose the medications that works best for your symptoms.
References
Ontaneda D, Rae-Grant AD. Management of acute exacerbations in multiple sclerosis. Ann Indian
Acad Neurol. 2009 Oct-Dec; 12(4): 264272.
Meca-Lallana JE, Hernndez-Clares R, Len-Hernndez A, Genovs, et al. Plasma exchange for
steroid-refractory relapses in multiple sclerosis: an observational, MRI pilot study. Clin Ther. 2013
Apr;35(4):474-85.
Habek M, Barun B, Pureti Z, et al. Treatment of steroid unresponsive relapse with plasma
exchange in aggressive multiple sclerosis. Ther Apher Dial. 2010 Jun;14(3):298-302.
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